A new method of 3D transient eddy current field calculation is proposed. The Maxwell equations with time component elimination （METCE） are derived under the assumption of magnetic quasi static approximation, especia...A new method of 3D transient eddy current field calculation is proposed. The Maxwell equations with time component elimination （METCE） are derived under the assumption of magnetic quasi static approximation, especially for the sample of low conductivity. Based on METCE, we deduce a more efficient reconstruction algorithm of a 3D transient eddy current field. The computational burden is greatly reduced through the new algorithm, and the computational efficiency is improved. This new algorithm decompounds the space-time variables into two individual variables. The idea is to solve the spatial vector component firstly, and then multiply it by the corresponded time component. The iterative methods based on METCE are introduced to recover the distribution of conductivity in magneto-acoustic tomography. The reconstructed images of conductivity are consistent with the original distribution, which validate the new method.展开更多
We present an efficient three-dimensional coupled-mode model based on the Fourier synthesis technique. In principle, this model is a one-way model, and hence provides satisfactory accuracy for problems where the forwa...We present an efficient three-dimensional coupled-mode model based on the Fourier synthesis technique. In principle, this model is a one-way model, and hence provides satisfactory accuracy for problems where the forward scattering dominates. At the same time, this model provides an efficiency gain of an order of magnitude or more over two-way coupled-mode models. This model can be applied to three-dimensional range-dependent problems with a slowly varying bathymetry or internal waves. A numerical example of the latter is demonstrated in this work. Comparisons of both accuracy and efficiency between the present model and a benchmark model are also provided.展开更多
In this paper our studies about the sequential testing program for predicting and identificating carcinogens, sequential discriminant method and cost- effectiveness analysis are summarized. The analysis of our databas...In this paper our studies about the sequential testing program for predicting and identificating carcinogens, sequential discriminant method and cost- effectiveness analysis are summarized. The analysis of our database of carcinogeniclty and genotoxicity of chemicals demonstrates the uncertainty . of short- term tests ( STTs ) to predict carcinogens and the results of most routine STTs are statistically dependent. We recommend the sequential testing program combining STTs and carclnogenicity assay, the optimal STT batteries, the rules of the sequential discrimination and the preferal choices of STTs tor specific chemical class. For illustrative pmposes the carclnogenicity prediction of several sample chamicals is presented. The results of cost-effectiveness analysis suggest that this program has vast social-economic effectiveness.展开更多
4,4'-Oxybis(benzoic acid)(Ⅰ)is an important monomer for making synthetic resin,heat resistant film and liquid crystal fiber,etc.It has been synthesized either by the oxidation of 4,4'-dimethyl diphenyl ether,...4,4'-Oxybis(benzoic acid)(Ⅰ)is an important monomer for making synthetic resin,heat resistant film and liquid crystal fiber,etc.It has been synthesized either by the oxidation of 4,4'-dimethyl diphenyl ether,or by the electrophilic substitution of diphenyl ether,these substituents introduced into the benzene ring can be further transformed into carboxylic groups.Diphenyl ethers are usually prepared from phenols and halobenzenes through Ullmann resction.Due to the high reaction temerature(usually above 200℃),long time heating and the formation of isomers,it is difficult to obtain pure products in high yields.展开更多
The possibility of co-deposition of Li(Ⅰ)and RE(Ⅲ)has been estimated by both theoretical analysis and experimental study on the influences of temperature and concen- tration of chloride on the deposition potential.B...The possibility of co-deposition of Li(Ⅰ)and RE(Ⅲ)has been estimated by both theoretical analysis and experimental study on the influences of temperature and concen- tration of chloride on the deposition potential.Both the electrochemical and electrolytic results clearly show that Li(Ⅰ)and RE(Ⅲ)can co-deposit on the Al-Cu electrode under selected conditions.展开更多
In this paper, a whole field solution to finite internally cracked plates is derived by complex variable method, where the equations of equilibrium and compatibility, the single value condition of displacements and th...In this paper, a whole field solution to finite internally cracked plates is derived by complex variable method, where the equations of equilibrium and compatibility, the single value condition of displacements and the traction-free condition on crack surfaces are satisfied exactly. The stress intensity factors of finite plates with central crack or eccentric crack or cracks emanating from a hole are calculated by using minimum potential energy principle to treat the boundary conditions excluding those on crack surfaces. As an application of the method to engineering problems, the computation about a finite rivet joint stiffened plate with cracks emanating from a hole is also performed. The numerical results show that the method presented in this paper gives rapid convergence and is much time-saving in computations.展开更多
In this paper, the eigen function expansions of displacements and stresses of bi-metal laminates with interface cracks are obtained. Furthermore, the stress intensity factors are determined by the variational method t...In this paper, the eigen function expansions of displacements and stresses of bi-metal laminates with interface cracks are obtained. Furthermore, the stress intensity factors are determined by the variational method to satisfy the boundary conditions and there are only line integrals in the variational equations due to the previous satisfaction of all basic equations. The computations show that this method of solution has the advantages of rapid convergency and time-saving. The results obtained by this method for homogeneous material agree with the known ones very well.展开更多
This paper reports a new chemiluminescence system i.e.luminol- H_2O_2-IO_4^- catalyzed by sulphide ion(S^(2-)).Based on this catalysis,a new chemiluminescence(CL)method for the determination of trace S^(2-)is pro- pos...This paper reports a new chemiluminescence system i.e.luminol- H_2O_2-IO_4^- catalyzed by sulphide ion(S^(2-)).Based on this catalysis,a new chemiluminescence(CL)method for the determination of trace S^(2-)is pro- posed.The detection limit is 0.2μg/LS^(2-),the linear dynamic range is 5μg to 100βμg/L S^(2-)and the variation coefficient at an sulphide concentration of 100μg/L S^(2-)is 4.5%(n=10).The method has been satisfactory applied to the determination of trace sulphide ion in water.展开更多
An automatic heat flux-temperature measuring system can be used to measure local body heat flux, local skin temperature, body core temperature, and ambient temperature, as well as mean body heat flux, mean skin temper...An automatic heat flux-temperature measuring system can be used to measure local body heat flux, local skin temperature, body core temperature, and ambient temperature, as well as mean body heat flux, mean skin temperature, physiological shell thermal insulation and suit thermal insulation. This paper describes the measuring principle, hardware construction, software program and the application in thermal measurements on divers.展开更多
A self-consistent-field—configuration interaction(SCF-CI)procedure of studying highly excited vibrational states of bent triatomic molecules is suggested and its application to O_3 is investigated.
GST-π was purified from human placenta and its antiserum was raised in rabbits. The antibody IgC was purified and degraded into Fab' fragment which was conjugated with horseradish peroxidase (HRP) using N-succini...GST-π was purified from human placenta and its antiserum was raised in rabbits. The antibody IgC was purified and degraded into Fab' fragment which was conjugated with horseradish peroxidase (HRP) using N-succinimidyl-4-(N-maleimido-methyl) cyclo-hexane-1-carboxylate (SMCC) as crosslinking reagent to produce Fab'-HRP conjugate. A sandwich ELISA was established for the microquantitative determination of GST-π. The sensitivity was 11 pg/tube, which was far more sensitive than the radioimmunoassay so far reported. Using this method, the serum GST-π of 41 cases normal adult was found to be 1.06±0.94 ng/ml. The upper limit of the normal value was 2.6 ng/ml. In 30 cases of primary hepatocarcinoma, the level of serum GST-π was 24.4± 17.4 ng/ml, which was 23 times higher than the normal average value (P<0.01). The positive rate was 90%. In contrast, serum GST-π in 25 cases of chronic hepatitis was determined to be 1.74±1.16 ng/ml, which was not significantly different from the normal value (P>0.05). The pseudo-positive rate was 12.0%.展开更多
The number of therapeutic monoclonal antibodies used in clinical trials has recently increased dramatically, leading to the development of optimized downstream purification processes[1]. Staphylococcal protein A （SPA...The number of therapeutic monoclonal antibodies used in clinical trials has recently increased dramatically, leading to the development of optimized downstream purification processes[1]. Staphylococcal protein A （SPA）, a cell-wall protein of Staphylococcus aureus, has been developed as a universal ligand for immunoglobulin G （IgG） purification because it binds specifically to the Fc portion of the IgG molecule of many mammals[2]. However, certain characteristics of SPA severely restrict the advancement of the antibody industry.展开更多
Inductively-coupled plasma mass spectrometry (ICP-MS) has made much progress since its birth in the late 1990s. This paper will give a rather systematic overview on the use of this technique in new devices and technol...Inductively-coupled plasma mass spectrometry (ICP-MS) has made much progress since its birth in the late 1990s. This paper will give a rather systematic overview on the use of this technique in new devices and technologies related to plasma source, sample-introducing device and detecting spectrometer etc. In this overview, an emphasis will be put on the evaluation of the ICP- MS technique in combination with a series of physical, chemical and biological techniques, such as laser ablation (LA), capillary electrophoresis (CE) and high performance liquid chromatograph (HPLC), along with their representative high accuracy and high sensitivity. Finally, comprehensive and fruitful applications of the ICP-MS and its combinative techniques in the detection of trace metallic elements and isotopes in complex biological and environmental samples will be revealed.展开更多
This paper discusses the Rb-Sr geochemical behaviour of illites in the sedimentary process, and points out that illites of the lmd and lm types could reach Sr-isotopic equilibrium with its environmental medium during ...This paper discusses the Rb-Sr geochemical behaviour of illites in the sedimentary process, and points out that illites of the lmd and lm types could reach Sr-isotopic equilibrium with its environmental medium during the sedimentary process and initial stage of diagenesis, and illite grains of different sizes have various Rb contents. A new dating method for sedimentary rocks----a dating model of illite grain Rb-Sr isochron----is established, in consideration of the geochemical process of Sr-isotopic homogenization and differentiation in the course of their formation and evolution. In addition, the paper concerns the application of the dating model to the Precambrian unmetamorphosed sedimentary rocks in western Henan Province, which gives satisfactory results coincident with the geological facts.展开更多
The penalty and hybrid methods are being much used in dealing with the general incompatible element, With the penalty method convergence can always be assured, but comparatively speaking its accuracy is lower, and the...The penalty and hybrid methods are being much used in dealing with the general incompatible element, With the penalty method convergence can always be assured, but comparatively speaking its accuracy is lower, and the condition number and sparsity are not so good. With the hybrid method, convergence can be assured only when the rank condition is satisfied. So the construction of the element is extremely limited. This paper presents the mixed hybrid penalty element method, which combines the two methods together. And it is proved theoretically that this new method is convergent, and it has the same accuracy, condition number and sparsity as the compatible element. That is to say, they are optimal to each other.Finally, a new triangle element for plate bending with nine freedom degrees is constructed with this method (three degreesof freedom are given on each corner -- one displacement and tworotations), the calculating formula of the element stiffness matrix is almost the same as that of the old triangle element for plate bending with nine degrees of freedom But it is converged to true solution with arbitrary irregrlar triangle subdivision. If the true solution u?H3 with this method the linear and quadratic rates of convergence are obtianed for three bending moments and for the displacement and two rotations respectively.展开更多
This paper presents an analytical solution for the production function and pressure distribution function of flow in infinite stratified oil reservoir with crosflow under the condition of constant wellbore pressure (C...This paper presents an analytical solution for the production function and pressure distribution function of flow in infinite stratified oil reservoir with crosflow under the condition of constant wellbore pressure (CWP condition) by Weber's integral transformation. The calculation results are shown in the form of curves and these results can be used to analyse unsteady flow test of production with CWP condition.展开更多
Prior to formation of the micelles of cationic surfactant (CSF), bromopyrogallol red (BPR) could exist in the forms of both monomer and oligomer After that, however, only BPR monomer existed. Nonionic surfactant OP-10...Prior to formation of the micelles of cationic surfactant (CSF), bromopyrogallol red (BPR) could exist in the forms of both monomer and oligomer After that, however, only BPR monomer existed. Nonionic surfactant OP-10 favoured the oligomerization of BPR monomer. The mixed micellar media prepared by mixing CSF and OP-10 in an appropriate ratio could be used for the sensitive and selective determination of Mo in Mo/W binary mixtures.展开更多
The electroanalytical behaviour of xanthophyll was studied by differential pulse polarography and cyclic voltammetry.The reduction wave of xanthophyll at -0.92V(v.s.Ag/AgCl)in 1.25% tetrabutyl ammonium chloride soluti...The electroanalytical behaviour of xanthophyll was studied by differential pulse polarography and cyclic voltammetry.The reduction wave of xanthophyll at -0.92V(v.s.Ag/AgCl)in 1.25% tetrabutyl ammonium chloride solution(TBAC)was found for the first time.The optimum conditions for the determination of xanthophyll by DPP were established. The results from the application of cyclic voltammetry to study electrode process behaviour showed that the electrode reaction of xanthophyll at a hanging mercury electrode is quasi-reversible reaction.展开更多
The microwave radiactivproperty of snow is studied using self-developed three band microwave radiometers. Experiments were carried out repeatedly from 1986 to 1989 in Northeast China The relation between brightness te...The microwave radiactivproperty of snow is studied using self-developed three band microwave radiometers. Experiments were carried out repeatedly from 1986 to 1989 in Northeast China The relation between brightness temperature and observation angle was obtained with both vertical and horizontal polarizations. The curves corresponding brightness temperature and snow depth were also drawn out for different frequency bands. The results demonstrate the application potential of the multifrequency microwave radiometer in this area.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos 51137004,61427806 and 51577184the Equipment Development Project of Chinese Academy of Sciences under Grant No YZ201507
文摘A new method of 3D transient eddy current field calculation is proposed. The Maxwell equations with time component elimination （METCE） are derived under the assumption of magnetic quasi static approximation, especially for the sample of low conductivity. Based on METCE, we deduce a more efficient reconstruction algorithm of a 3D transient eddy current field. The computational burden is greatly reduced through the new algorithm, and the computational efficiency is improved. This new algorithm decompounds the space-time variables into two individual variables. The idea is to solve the spatial vector component firstly, and then multiply it by the corresponded time component. The iterative methods based on METCE are introduced to recover the distribution of conductivity in magneto-acoustic tomography. The reconstructed images of conductivity are consistent with the original distribution, which validate the new method.
基金Supported by the National Natural Science Foundation of China under Grant No 11774374the Natural Science Foundation of Shandong Province of China under Grant No ZR2016AL10
文摘We present an efficient three-dimensional coupled-mode model based on the Fourier synthesis technique. In principle, this model is a one-way model, and hence provides satisfactory accuracy for problems where the forward scattering dominates. At the same time, this model provides an efficiency gain of an order of magnitude or more over two-way coupled-mode models. This model can be applied to three-dimensional range-dependent problems with a slowly varying bathymetry or internal waves. A numerical example of the latter is demonstrated in this work. Comparisons of both accuracy and efficiency between the present model and a benchmark model are also provided.
文摘In this paper our studies about the sequential testing program for predicting and identificating carcinogens, sequential discriminant method and cost- effectiveness analysis are summarized. The analysis of our database of carcinogeniclty and genotoxicity of chemicals demonstrates the uncertainty . of short- term tests ( STTs ) to predict carcinogens and the results of most routine STTs are statistically dependent. We recommend the sequential testing program combining STTs and carclnogenicity assay, the optimal STT batteries, the rules of the sequential discrimination and the preferal choices of STTs tor specific chemical class. For illustrative pmposes the carclnogenicity prediction of several sample chamicals is presented. The results of cost-effectiveness analysis suggest that this program has vast social-economic effectiveness.
文摘4,4'-Oxybis(benzoic acid)(Ⅰ)is an important monomer for making synthetic resin,heat resistant film and liquid crystal fiber,etc.It has been synthesized either by the oxidation of 4,4'-dimethyl diphenyl ether,or by the electrophilic substitution of diphenyl ether,these substituents introduced into the benzene ring can be further transformed into carboxylic groups.Diphenyl ethers are usually prepared from phenols and halobenzenes through Ullmann resction.Due to the high reaction temerature(usually above 200℃),long time heating and the formation of isomers,it is difficult to obtain pure products in high yields.
文摘The possibility of co-deposition of Li(Ⅰ)and RE(Ⅲ)has been estimated by both theoretical analysis and experimental study on the influences of temperature and concen- tration of chloride on the deposition potential.Both the electrochemical and electrolytic results clearly show that Li(Ⅰ)and RE(Ⅲ)can co-deposit on the Al-Cu electrode under selected conditions.
文摘In this paper, a whole field solution to finite internally cracked plates is derived by complex variable method, where the equations of equilibrium and compatibility, the single value condition of displacements and the traction-free condition on crack surfaces are satisfied exactly. The stress intensity factors of finite plates with central crack or eccentric crack or cracks emanating from a hole are calculated by using minimum potential energy principle to treat the boundary conditions excluding those on crack surfaces. As an application of the method to engineering problems, the computation about a finite rivet joint stiffened plate with cracks emanating from a hole is also performed. The numerical results show that the method presented in this paper gives rapid convergence and is much time-saving in computations.
文摘In this paper, the eigen function expansions of displacements and stresses of bi-metal laminates with interface cracks are obtained. Furthermore, the stress intensity factors are determined by the variational method to satisfy the boundary conditions and there are only line integrals in the variational equations due to the previous satisfaction of all basic equations. The computations show that this method of solution has the advantages of rapid convergency and time-saving. The results obtained by this method for homogeneous material agree with the known ones very well.
文摘This paper reports a new chemiluminescence system i.e.luminol- H_2O_2-IO_4^- catalyzed by sulphide ion(S^(2-)).Based on this catalysis,a new chemiluminescence(CL)method for the determination of trace S^(2-)is pro- posed.The detection limit is 0.2μg/LS^(2-),the linear dynamic range is 5μg to 100βμg/L S^(2-)and the variation coefficient at an sulphide concentration of 100μg/L S^(2-)is 4.5%(n=10).The method has been satisfactory applied to the determination of trace sulphide ion in water.
文摘An automatic heat flux-temperature measuring system can be used to measure local body heat flux, local skin temperature, body core temperature, and ambient temperature, as well as mean body heat flux, mean skin temperature, physiological shell thermal insulation and suit thermal insulation. This paper describes the measuring principle, hardware construction, software program and the application in thermal measurements on divers.
文摘A self-consistent-field—configuration interaction(SCF-CI)procedure of studying highly excited vibrational states of bent triatomic molecules is suggested and its application to O_3 is investigated.
文摘GST-π was purified from human placenta and its antiserum was raised in rabbits. The antibody IgC was purified and degraded into Fab' fragment which was conjugated with horseradish peroxidase (HRP) using N-succinimidyl-4-(N-maleimido-methyl) cyclo-hexane-1-carboxylate (SMCC) as crosslinking reagent to produce Fab'-HRP conjugate. A sandwich ELISA was established for the microquantitative determination of GST-π. The sensitivity was 11 pg/tube, which was far more sensitive than the radioimmunoassay so far reported. Using this method, the serum GST-π of 41 cases normal adult was found to be 1.06±0.94 ng/ml. The upper limit of the normal value was 2.6 ng/ml. In 30 cases of primary hepatocarcinoma, the level of serum GST-π was 24.4± 17.4 ng/ml, which was 23 times higher than the normal average value (P<0.01). The positive rate was 90%. In contrast, serum GST-π in 25 cases of chronic hepatitis was determined to be 1.74±1.16 ng/ml, which was not significantly different from the normal value (P>0.05). The pseudo-positive rate was 12.0%.
基金supported by grants from the National High Technology Research and Development Program of China(863 Program)(No.2012AA020304)the National Natural Science Foundation of China(Grant No.31300643)the Innovation Fund for Postgraduate Students from the Simcere Pharmaceutical Company(No.02704051)
文摘The number of therapeutic monoclonal antibodies used in clinical trials has recently increased dramatically, leading to the development of optimized downstream purification processes[1]. Staphylococcal protein A （SPA）, a cell-wall protein of Staphylococcus aureus, has been developed as a universal ligand for immunoglobulin G （IgG） purification because it binds specifically to the Fc portion of the IgG molecule of many mammals[2]. However, certain characteristics of SPA severely restrict the advancement of the antibody industry.
文摘Inductively-coupled plasma mass spectrometry (ICP-MS) has made much progress since its birth in the late 1990s. This paper will give a rather systematic overview on the use of this technique in new devices and technologies related to plasma source, sample-introducing device and detecting spectrometer etc. In this overview, an emphasis will be put on the evaluation of the ICP- MS technique in combination with a series of physical, chemical and biological techniques, such as laser ablation (LA), capillary electrophoresis (CE) and high performance liquid chromatograph (HPLC), along with their representative high accuracy and high sensitivity. Finally, comprehensive and fruitful applications of the ICP-MS and its combinative techniques in the detection of trace metallic elements and isotopes in complex biological and environmental samples will be revealed.
基金This research was financially supported by the Academia Sinica Foundation
文摘This paper discusses the Rb-Sr geochemical behaviour of illites in the sedimentary process, and points out that illites of the lmd and lm types could reach Sr-isotopic equilibrium with its environmental medium during the sedimentary process and initial stage of diagenesis, and illite grains of different sizes have various Rb contents. A new dating method for sedimentary rocks----a dating model of illite grain Rb-Sr isochron----is established, in consideration of the geochemical process of Sr-isotopic homogenization and differentiation in the course of their formation and evolution. In addition, the paper concerns the application of the dating model to the Precambrian unmetamorphosed sedimentary rocks in western Henan Province, which gives satisfactory results coincident with the geological facts.
文摘The penalty and hybrid methods are being much used in dealing with the general incompatible element, With the penalty method convergence can always be assured, but comparatively speaking its accuracy is lower, and the condition number and sparsity are not so good. With the hybrid method, convergence can be assured only when the rank condition is satisfied. So the construction of the element is extremely limited. This paper presents the mixed hybrid penalty element method, which combines the two methods together. And it is proved theoretically that this new method is convergent, and it has the same accuracy, condition number and sparsity as the compatible element. That is to say, they are optimal to each other.Finally, a new triangle element for plate bending with nine freedom degrees is constructed with this method (three degreesof freedom are given on each corner -- one displacement and tworotations), the calculating formula of the element stiffness matrix is almost the same as that of the old triangle element for plate bending with nine degrees of freedom But it is converged to true solution with arbitrary irregrlar triangle subdivision. If the true solution u?H3 with this method the linear and quadratic rates of convergence are obtianed for three bending moments and for the displacement and two rotations respectively.
文摘This paper presents an analytical solution for the production function and pressure distribution function of flow in infinite stratified oil reservoir with crosflow under the condition of constant wellbore pressure (CWP condition) by Weber's integral transformation. The calculation results are shown in the form of curves and these results can be used to analyse unsteady flow test of production with CWP condition.
文摘Prior to formation of the micelles of cationic surfactant (CSF), bromopyrogallol red (BPR) could exist in the forms of both monomer and oligomer After that, however, only BPR monomer existed. Nonionic surfactant OP-10 favoured the oligomerization of BPR monomer. The mixed micellar media prepared by mixing CSF and OP-10 in an appropriate ratio could be used for the sensitive and selective determination of Mo in Mo/W binary mixtures.
文摘The electroanalytical behaviour of xanthophyll was studied by differential pulse polarography and cyclic voltammetry.The reduction wave of xanthophyll at -0.92V(v.s.Ag/AgCl)in 1.25% tetrabutyl ammonium chloride solution(TBAC)was found for the first time.The optimum conditions for the determination of xanthophyll by DPP were established. The results from the application of cyclic voltammetry to study electrode process behaviour showed that the electrode reaction of xanthophyll at a hanging mercury electrode is quasi-reversible reaction.
基金The Project supported by National National Science Foundation
文摘The microwave radiactivproperty of snow is studied using self-developed three band microwave radiometers. Experiments were carried out repeatedly from 1986 to 1989 in Northeast China The relation between brightness temperature and observation angle was obtained with both vertical and horizontal polarizations. The curves corresponding brightness temperature and snow depth were also drawn out for different frequency bands. The results demonstrate the application potential of the multifrequency microwave radiometer in this area.
