The purpose of this research is to determine the anti-wear capability of new advanced low viscosity engine oil to meet the Sequence IVB requirement of ILSAC GF-6 specification, which envisages that the first certifica...The purpose of this research is to determine the anti-wear capability of new advanced low viscosity engine oil to meet the Sequence IVB requirement of ILSAC GF-6 specification, which envisages that the first certification will be realized in 2020. The anti-wear performance of the aged candidate GF-6 engine oils was evaluated using the laboratory bench test rigs such as the Falex Pin & Vee Block test machine and the high frequency reciprocating rig (HFRR). The worn surfaces were analyzed by X-ray photoelectron spectroscopy (XPS). The remarkable anti-wear performance of the developed GF-6 engine oil was also confirmed in the Sequence IVB test. The results indicate that by appropriately selecting and balancing the calcium detergent additives the wear loss of cam and tappet determined in the Sequence IVB test at low temperature could be significantly reduced. The time for occurrence of the intersection of the base and acid values corresponds well with the increase of wear of cam tappet of the IVB engine test.展开更多
This work deals with the interaction of neutrino with the nucleon considering data taken from different experiments. It is assumed that the interaction of neutrino with nucleons go through the intermediate vector boso...This work deals with the interaction of neutrino with the nucleon considering data taken from different experiments. It is assumed that the interaction of neutrino with nucleons go through the intermediate vector boson (IVB) which may be the W or Z with effective mass of the order of 80 GeV. The neutrino wave function is obtained via perturbation technique to calculate the weak leptonic current. On the other hand, the quark current is estimated using the measured experimental data of deep inelastic scattering of neutrino-nucleon interaction. Eventually the total interaction transition matrix is calculated as a function of momentum transfer square, q2 and qualitatively compared with the available experimental data. Besides, a comparative study is also done to explore the influence of the target composition during the neutrino weak interactions. In this context an investigation of neutrino-proton and neutrino-neutron interactions are carried out to calculate the deep inelastic cross section in both cases.展开更多
Background:Previous studies have shown that pegylated liposomal doxorubicin(LD)is effective in the treatment of relapsing or recalcitrant cutaneous T-cell lymphoma. Objectives:To evaluate the activity and toxicity of ...Background:Previous studies have shown that pegylated liposomal doxorubicin(LD)is effective in the treatment of relapsing or recalcitrant cutaneous T-cell lymphoma. Objectives:To evaluate the activity and toxicity of LD in patients with stage IVB mycosis fungoides (MF). Methods:In this retrospective study, we evaluated outcomes and recorded adverse effects in 10 patients with MF (seven men and three women) with extracutaneous involvement. Patients were treated with LD 20 mg m-2 administered intravenously every 4 weeks. Results:All patients received at least two cycles of LD, three patients received four cycles and one patient received six cycles. Three patients (30%) had a partial response and two patients had stable disease. Grade 1-2 leucopenia occurred in three of the 10 patients, and grade 4 leucopenia in one. Three patients had grade 2 palmoplantar erythrodysaesthesia. Conclusions:This study demonstrates that LD is beneficial in terms of activity and toxicity in stage IVB MF. These observations should be verified in larger studies.展开更多
The fascinating chemical structure and broad application prospect of Keggin-type polyoxometalates(POMs)have attracted many chemists to explore and discover continuously.Unlike the traditional Keggin,larger metal atomi...The fascinating chemical structure and broad application prospect of Keggin-type polyoxometalates(POMs)have attracted many chemists to explore and discover continuously.Unlike the traditional Keggin,larger metal atomic radius,higher metal coordinated numbers,lower metal valence states and other features allow the group IVB metal-based Keggin(IVB-Keggin)more space and unknown in terms of structure and performance.Herein,density functional theory(DFT)calculations were performed to explore the influences including cores,shells,caps,and terminal ligands,et al.on IVB-Keggin,and analyze the possibility of novel structure synthesis.From the perspective of multi-layer onion-like clusters,molecular energy level,host-guest interaction energy,surface charge and covalent bond polarity can be further adjusted to achieve the oriented design of functional IVB-Keggin.These insights are expected to provide theoretical support for experimental synthesis,opening a new perspective to understand the growth of Keggin.展开更多
1,3-二氯四甲基二硅氧烷相继与环戊二烯基钠、钠砂及 MCl_4反应,制得标题化合物:O(SiMe_2)_2(C_5H_4)_2MCl_2(1,M=Ti;2,M=Zr;3,M=Hf).考察了1的卤素置换反应:1与(NH_4)_2SiF_6作用生成相应的二氟化物4,4与氢溴酸作用生成相应的二溴化物5...1,3-二氯四甲基二硅氧烷相继与环戊二烯基钠、钠砂及 MCl_4反应,制得标题化合物:O(SiMe_2)_2(C_5H_4)_2MCl_2(1,M=Ti;2,M=Zr;3,M=Hf).考察了1的卤素置换反应:1与(NH_4)_2SiF_6作用生成相应的二氟化物4,4与氢溴酸作用生成相应的二溴化物5.经元素分析,UV,~1H(^(13)C)NMR 和 MS 表征了它们的结构,并利用 X 射线衍射法测定了2和3的晶体和分子结构.化合物1,2和3的有关结构数据比较表明,由于中心金属的不同而引起其键长和键角的差异与其碳桥类似物(CH_2)_3(C_5H_4)_2MCl_2的情况相似.展开更多
A pair of novel geometrically isomeric triterpenoid saponins named escins IVa and IVb, together with known escins Ia and Ib. were isolated from the seeds of Aesculus chinensis. Their structures were determined on the ...A pair of novel geometrically isomeric triterpenoid saponins named escins IVa and IVb, together with known escins Ia and Ib. were isolated from the seeds of Aesculus chinensis. Their structures were determined on the basis of spectroscopic evidences and comparison.展开更多
基金supported by the Research Project of China Petrochemical Corporation (SINOPEC 114005)
文摘The purpose of this research is to determine the anti-wear capability of new advanced low viscosity engine oil to meet the Sequence IVB requirement of ILSAC GF-6 specification, which envisages that the first certification will be realized in 2020. The anti-wear performance of the aged candidate GF-6 engine oils was evaluated using the laboratory bench test rigs such as the Falex Pin & Vee Block test machine and the high frequency reciprocating rig (HFRR). The worn surfaces were analyzed by X-ray photoelectron spectroscopy (XPS). The remarkable anti-wear performance of the developed GF-6 engine oil was also confirmed in the Sequence IVB test. The results indicate that by appropriately selecting and balancing the calcium detergent additives the wear loss of cam and tappet determined in the Sequence IVB test at low temperature could be significantly reduced. The time for occurrence of the intersection of the base and acid values corresponds well with the increase of wear of cam tappet of the IVB engine test.
文摘This work deals with the interaction of neutrino with the nucleon considering data taken from different experiments. It is assumed that the interaction of neutrino with nucleons go through the intermediate vector boson (IVB) which may be the W or Z with effective mass of the order of 80 GeV. The neutrino wave function is obtained via perturbation technique to calculate the weak leptonic current. On the other hand, the quark current is estimated using the measured experimental data of deep inelastic scattering of neutrino-nucleon interaction. Eventually the total interaction transition matrix is calculated as a function of momentum transfer square, q2 and qualitatively compared with the available experimental data. Besides, a comparative study is also done to explore the influence of the target composition during the neutrino weak interactions. In this context an investigation of neutrino-proton and neutrino-neutron interactions are carried out to calculate the deep inelastic cross section in both cases.
文摘Background:Previous studies have shown that pegylated liposomal doxorubicin(LD)is effective in the treatment of relapsing or recalcitrant cutaneous T-cell lymphoma. Objectives:To evaluate the activity and toxicity of LD in patients with stage IVB mycosis fungoides (MF). Methods:In this retrospective study, we evaluated outcomes and recorded adverse effects in 10 patients with MF (seven men and three women) with extracutaneous involvement. Patients were treated with LD 20 mg m-2 administered intravenously every 4 weeks. Results:All patients received at least two cycles of LD, three patients received four cycles and one patient received six cycles. Three patients (30%) had a partial response and two patients had stable disease. Grade 1-2 leucopenia occurred in three of the 10 patients, and grade 4 leucopenia in one. Three patients had grade 2 palmoplantar erythrodysaesthesia. Conclusions:This study demonstrates that LD is beneficial in terms of activity and toxicity in stage IVB MF. These observations should be verified in larger studies.
基金financially supported by the National Natural Science Foundation of China(NSFC,Nos.22225109,22071109,92061101,22173016 and 22301084)the China Postdoctoral Science Foundation(No.2023M741232)。
文摘The fascinating chemical structure and broad application prospect of Keggin-type polyoxometalates(POMs)have attracted many chemists to explore and discover continuously.Unlike the traditional Keggin,larger metal atomic radius,higher metal coordinated numbers,lower metal valence states and other features allow the group IVB metal-based Keggin(IVB-Keggin)more space and unknown in terms of structure and performance.Herein,density functional theory(DFT)calculations were performed to explore the influences including cores,shells,caps,and terminal ligands,et al.on IVB-Keggin,and analyze the possibility of novel structure synthesis.From the perspective of multi-layer onion-like clusters,molecular energy level,host-guest interaction energy,surface charge and covalent bond polarity can be further adjusted to achieve the oriented design of functional IVB-Keggin.These insights are expected to provide theoretical support for experimental synthesis,opening a new perspective to understand the growth of Keggin.
文摘1,3-二氯四甲基二硅氧烷相继与环戊二烯基钠、钠砂及 MCl_4反应,制得标题化合物:O(SiMe_2)_2(C_5H_4)_2MCl_2(1,M=Ti;2,M=Zr;3,M=Hf).考察了1的卤素置换反应:1与(NH_4)_2SiF_6作用生成相应的二氟化物4,4与氢溴酸作用生成相应的二溴化物5.经元素分析,UV,~1H(^(13)C)NMR 和 MS 表征了它们的结构,并利用 X 射线衍射法测定了2和3的晶体和分子结构.化合物1,2和3的有关结构数据比较表明,由于中心金属的不同而引起其键长和键角的差异与其碳桥类似物(CH_2)_3(C_5H_4)_2MCl_2的情况相似.
文摘A pair of novel geometrically isomeric triterpenoid saponins named escins IVa and IVb, together with known escins Ia and Ib. were isolated from the seeds of Aesculus chinensis. Their structures were determined on the basis of spectroscopic evidences and comparison.
