Background:Understanding the neurophysiological mechanisms of Amblyopia,a neurodevelopmental disorder of the visual cortex,will bring us closer to full recovery.Past findings have been contradictory.Results have shown...Background:Understanding the neurophysiological mechanisms of Amblyopia,a neurodevelopmental disorder of the visual cortex,will bring us closer to full recovery.Past findings have been contradictory.Results have shown that despite having severe acuity impairment,amblyopes can nonetheless perceive sharp edges.In this study,we explore the representation of blur through a series of image blur-discrimination and matching tasks,to understand more about the amblyopes’visual system.Methods:Monocular image blur-discrimination thresholds were measured in a spatial two-alternative forced-choice procedure whereby subjects had to decide which image was the blurriest.Subjects also had to interocularly match pictures that were identical to those used for the image blur discrimination task.Ten amblyopes,as well as a group of ten controls were under study.Results:Data on amblyopes and controls will be presented for both experiments.According to previous research that was done on blur-edge discrimination and matching,we predict that subjects’performance will follow a dipper function,that is,all observers will be better at discriminating between both images when a small amount of blur is applied rather than when the image is either sharp or very blurry.We also predict that amblyopes’blur discrimination will be noisier,but that they will paradoxically be able to match the sharpness of the images presented in the matching task.Conclusions:This would confirm our hypothesis about amblyopes’visual system,that they can represent blur levels defined by spatial frequencies that are beyond their resolution limit,and would also raise interesting questions about the visual system in general regarding the different perceptions driven by images versus edges.展开更多
Proton radiography has provided a potential development direction for advanced hydrotesting, and its image blur is a crucial point that needs to be deeply studied. In this article, numerical simulation by using the Mo...Proton radiography has provided a potential development direction for advanced hydrotesting, and its image blur is a crucial point that needs to be deeply studied. In this article, numerical simulation by using the Monte Carlo code Geant4 has been implemented to investigate the entire physics mechanism of high energy proton beam travelling through the object and beamline and arriving at the image plane. This article will mainly discuss the various factors which cause the image blur, including the chromatic aberration of the imaging beamline, the insumcient modulation of an incident particle's transverse displacement and angle deviation, the longitudinal length of an object, the influence of containment vessel and otherwise.展开更多
Proton radiography is a new tool for advanced hydrotesting. This article will discuss the basic concept of proton radiography first, especially the magnetic lens system. Then a scenario of 50 GeV imaging beamline will...Proton radiography is a new tool for advanced hydrotesting. This article will discuss the basic concept of proton radiography first, especially the magnetic lens system. Then a scenario of 50 GeV imaging beamline will be described in every particular, including the matching section, Zumbro lens system and imaging system. The simulation result shows that the scenario of imaging beamline performs well, and the influence of secondary particles can be neglected.展开更多
文摘Background:Understanding the neurophysiological mechanisms of Amblyopia,a neurodevelopmental disorder of the visual cortex,will bring us closer to full recovery.Past findings have been contradictory.Results have shown that despite having severe acuity impairment,amblyopes can nonetheless perceive sharp edges.In this study,we explore the representation of blur through a series of image blur-discrimination and matching tasks,to understand more about the amblyopes’visual system.Methods:Monocular image blur-discrimination thresholds were measured in a spatial two-alternative forced-choice procedure whereby subjects had to decide which image was the blurriest.Subjects also had to interocularly match pictures that were identical to those used for the image blur discrimination task.Ten amblyopes,as well as a group of ten controls were under study.Results:Data on amblyopes and controls will be presented for both experiments.According to previous research that was done on blur-edge discrimination and matching,we predict that subjects’performance will follow a dipper function,that is,all observers will be better at discriminating between both images when a small amount of blur is applied rather than when the image is either sharp or very blurry.We also predict that amblyopes’blur discrimination will be noisier,but that they will paradoxically be able to match the sharpness of the images presented in the matching task.Conclusions:This would confirm our hypothesis about amblyopes’visual system,that they can represent blur levels defined by spatial frequencies that are beyond their resolution limit,and would also raise interesting questions about the visual system in general regarding the different perceptions driven by images versus edges.
基金Supported by National Natural Science Foundation of China(11205144).National Natural Science Foundation of China(11176001)Science and Technology Development Program of China Academy of Engineering Physics(2010A042016)
文摘Proton radiography has provided a potential development direction for advanced hydrotesting, and its image blur is a crucial point that needs to be deeply studied. In this article, numerical simulation by using the Monte Carlo code Geant4 has been implemented to investigate the entire physics mechanism of high energy proton beam travelling through the object and beamline and arriving at the image plane. This article will mainly discuss the various factors which cause the image blur, including the chromatic aberration of the imaging beamline, the insumcient modulation of an incident particle's transverse displacement and angle deviation, the longitudinal length of an object, the influence of containment vessel and otherwise.
基金Supported by Science and Technology Research Development Program of CAEP(2010A042016)
文摘Proton radiography is a new tool for advanced hydrotesting. This article will discuss the basic concept of proton radiography first, especially the magnetic lens system. Then a scenario of 50 GeV imaging beamline will be described in every particular, including the matching section, Zumbro lens system and imaging system. The simulation result shows that the scenario of imaging beamline performs well, and the influence of secondary particles can be neglected.