Better understanding of the immunological mechanisms implying the insemination and the infertility of some menand women is needed and crucial to the development of an effective immunocontraceptive method. To provide g...Better understanding of the immunological mechanisms implying the insemination and the infertility of some menand women is needed and crucial to the development of an effective immunocontraceptive method. To provide goodprotection against conception or infection, and avoid any possible and unexpected comlications which immunocontra-ceptive 'vaccine' may arise of , it seems the right time for scientists to create a virtually new thinking for this extremelyurgent and important issue. This conceptual article describes our original thoughts of the future development of im-munocntraceptives, preferably, based on immunoglobulins rather than vaccines, against human sperm specific antigensand seminal plasma immunosuppressive factors. Its general correctness, advantages and feasibility for fertility regula-tion and prevention of infection are discussed. (Asian J Androl 1999 Sep; 1: 87-93)展开更多
文摘Better understanding of the immunological mechanisms implying the insemination and the infertility of some menand women is needed and crucial to the development of an effective immunocontraceptive method. To provide goodprotection against conception or infection, and avoid any possible and unexpected comlications which immunocontra-ceptive 'vaccine' may arise of , it seems the right time for scientists to create a virtually new thinking for this extremelyurgent and important issue. This conceptual article describes our original thoughts of the future development of im-munocntraceptives, preferably, based on immunoglobulins rather than vaccines, against human sperm specific antigensand seminal plasma immunosuppressive factors. Its general correctness, advantages and feasibility for fertility regula-tion and prevention of infection are discussed. (Asian J Androl 1999 Sep; 1: 87-93)
