Recently,some severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants represented by B.1.7(Alpha),B.1.351(Beta),P1(Gamma),B.1.617(Delta)and B.1.529(Omicron)have higher transmission and pathogenicity.Especi...Recently,some severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants represented by B.1.7(Alpha),B.1.351(Beta),P1(Gamma),B.1.617(Delta)and B.1.529(Omicron)have higher transmission and pathogenicity.Especially,Omicron causes global panic because of its high mutation in infectivity and vaccine escape,and their emergence makes the epidemic more difficult to control.The latest research reports indicate that these new corona mutants may first be mutated in the special population of immunosuppressive patients,and long-term infection and artificial immunotherapy may promote the variation of SARS-CoV-2.Not only that,there are a large number of congenital or acquired immunosuppressive patients worldwide,and immunosuppressive patients infected with SARS-CoV-2 will also have different impacts on social public health security.Therefore,we should pay more attention to the immunosuppressive population.This paper will briefly analyze the correlation between immunosuppressive population and SARS-CoV-2 variation in the form of review.展开更多
基金General Project of Huoshenshan Hospital Scientific Research(No.HSS-217)COVID-19 Fund Project of No.940 Hospital(No.20yjky020)。
文摘Recently,some severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)variants represented by B.1.7(Alpha),B.1.351(Beta),P1(Gamma),B.1.617(Delta)and B.1.529(Omicron)have higher transmission and pathogenicity.Especially,Omicron causes global panic because of its high mutation in infectivity and vaccine escape,and their emergence makes the epidemic more difficult to control.The latest research reports indicate that these new corona mutants may first be mutated in the special population of immunosuppressive patients,and long-term infection and artificial immunotherapy may promote the variation of SARS-CoV-2.Not only that,there are a large number of congenital or acquired immunosuppressive patients worldwide,and immunosuppressive patients infected with SARS-CoV-2 will also have different impacts on social public health security.Therefore,we should pay more attention to the immunosuppressive population.This paper will briefly analyze the correlation between immunosuppressive population and SARS-CoV-2 variation in the form of review.