Marginal bone loss during bone healing exists around non-submerged dental implants. The aim of this study was to identify the relationship between different degrees of marginal bone loss during bone healing and the sa...Marginal bone loss during bone healing exists around non-submerged dental implants. The aim of this study was to identify the relationship between different degrees of marginal bone loss during bone healing and the salivary microbiome. One hundred patients were recruited, and marginal bone loss around their implants was measured using cone beam computed tomography during a 3-month healing period. The patients were divided into three groups according to the severity of marginal bone loss.Saliva samples were collected from all subjected and were analysed using 16 SMiSeq sequencing. Although the overall structure of the microbial community was not dramatically altered, the relative abundance of several taxonomic groups noticeably changed. The abundance of species in the phyla Spirochaeta and Synergistetes increased significantly as the bone loss became more severe. Species within the genus Treponema also exhibited increased abundance, whereas Veillonella, Haemophilus and Leptotrichia exhibited reduced abundances, in groups with more bone loss. Porphyromonasgingivalis, Treponemadenticola and Streptococcus intermedius were significantly more abundant in the moderate group and/or severe group. The severity of marginal bone loss around the non-submerged implant was associated with dissimilar taxonomic compositions. An increased severity of marginal bone loss was related to increased proportions of periodontal pathogenic species. These data suggest a potential role of microbes in the progression of marginal bone loss during bone healing.展开更多
Objectives: To calculate the incidence of ectopic pregnancy in cases with recurrent early pregnancy loss and cases of recurrent implantation failure. Methods and materials: This is a retrospective cohort study. 200 wo...Objectives: To calculate the incidence of ectopic pregnancy in cases with recurrent early pregnancy loss and cases of recurrent implantation failure. Methods and materials: This is a retrospective cohort study. 200 women were recruited from the infertility clinic at shat by maternity university hospital seeking fertility. 100 of them were with history of recurrent implantation failure (RIF) and 100 with history of recurrent pregnancy loss (RPL). Revisiting their hospital files for the history of ectopic pregnancy was done. Results: 8% of cases of RPL had history of ectopic pregnancy while only 6% of cases of RIF had the history. There was no significant difference between the two groups (p = 0.579). There was significantly higher incidence of ectopic pregnancy in both groups if compared with the general population (p = 0.0001 and 0.043) in RPL and RIF consecutively. Conclusions: RPL and RIF may be considered as a risk factor for ectopic pregnancy.展开更多
<b><span>Background:</span></b><span> The objective of this meta-analysis was to assess whether mini-</span><span>implants </span><span>have</span><span&g...<b><span>Background:</span></b><span> The objective of this meta-analysis was to assess whether mini-</span><span>implants </span><span>have</span><span> added benefit in terms of implants success rate and average bone loss over conventional-sized implants after one year of follow-up.</span><span> </span><b><span>Methods: </span></b><span>An electronic search of randomized clinical trials was conducted in MEDLINE (via PubMed), Cochrane Central Register of Clinical Trials (CENTRAL) and Web of Science for studies including complete or partial edentulous patients requiring two or four mini-implants or conventional/</span><span> </span><span>standard-sized implants in the maxilla or mandible for implant-supported removable prostheses who completed 12 months of follow-up. </span><b><span>Results:</span></b><span> The search provided 194 unique articles which were screened for title and abstract. Screening generated 12 articles which went through full-text analysis using eligibility criteria, and 4 articles were included for meta-analysis. Meta-analysis of these studies indicated a non-significant difference in the success rate between the two interventions (OR = 1.69 [0.74, 3.85;p = 0.21]). Bone loss estimates resulted in a significant bone reduction (Mean Difference = </span><span>-</span><span>0.74 [</span><span>-</span><span>0.95, </span><span>-</span><span>0.53;p < 0.05]) in favor of two mini-implants when compared with two conventional-sized implants, but when compared four mini</span><span>- </span><span> </span><span>with two conventional-sized implants</span><span>,</span><span> the estimates were non-significant </span><span>(Mean Difference = </span><span>-</span><span>0.24 [</span><span>-</span><span>0.69, 0.20;p = 0.29]). </span><b><span>Conclusion: </span></b><span>The current evidence does not provide solid evidence of the benefits of one intervention over the other. More studies with follow-up times of 10 and more years are needed as current studies have described the short-term outcomes.</span>展开更多
目的探讨肝移植术后植入人工耳蜗的感音神经性耳聋老年患者临床处治特点和注意事项。方法肝移植术后老年患者1例,62岁女性,双耳感音神经性耳聋(全聋)超过10年,肝移植术后长期服用抗排异、激素药物,移植后8年行人工耳蜗植入术。针对患者...目的探讨肝移植术后植入人工耳蜗的感音神经性耳聋老年患者临床处治特点和注意事项。方法肝移植术后老年患者1例,62岁女性,双耳感音神经性耳聋(全聋)超过10年,肝移植术后长期服用抗排异、激素药物,移植后8年行人工耳蜗植入术。针对患者的特殊病史和身体条件,人工耳蜗植入术后除进行常规开机外,给予肝功能保护、监测他克莫司浓度、感染、心理护理等处治措施。结果肝移植老年患者开机1年8个月后助听听阈≤35 dB HL,单音节识别率70.67%,双音节识别率85%,言语空间音质听力量表(the speech,spatial and qualities of hearing scale,SSQ)得分19分。未见与肝移植相关并发症,术后心理状态明显改善,生活质量显著提高。结论人工耳蜗植入术对肝移植后接受免疫抑制治疗的老年患者是一种安全有效的干预手段。突出抗感染、提升免疫力对确保手术安全性、有效性至关重要。展开更多
基金supported by grants from the National Natural Science Foundation of China(NSFC8137117381571001)+2 种基金State Key Laboratory of Oral Diseases(SKLOD201704)International Team for Implantology(Grant No.975_2014,Basel,Switzerland)to Quan Yuanthe National Key R&D Program of China during the 13th Five-Year Plan(2016YFC1102700)to Xue-Dong Zhou
文摘Marginal bone loss during bone healing exists around non-submerged dental implants. The aim of this study was to identify the relationship between different degrees of marginal bone loss during bone healing and the salivary microbiome. One hundred patients were recruited, and marginal bone loss around their implants was measured using cone beam computed tomography during a 3-month healing period. The patients were divided into three groups according to the severity of marginal bone loss.Saliva samples were collected from all subjected and were analysed using 16 SMiSeq sequencing. Although the overall structure of the microbial community was not dramatically altered, the relative abundance of several taxonomic groups noticeably changed. The abundance of species in the phyla Spirochaeta and Synergistetes increased significantly as the bone loss became more severe. Species within the genus Treponema also exhibited increased abundance, whereas Veillonella, Haemophilus and Leptotrichia exhibited reduced abundances, in groups with more bone loss. Porphyromonasgingivalis, Treponemadenticola and Streptococcus intermedius were significantly more abundant in the moderate group and/or severe group. The severity of marginal bone loss around the non-submerged implant was associated with dissimilar taxonomic compositions. An increased severity of marginal bone loss was related to increased proportions of periodontal pathogenic species. These data suggest a potential role of microbes in the progression of marginal bone loss during bone healing.
文摘Objectives: To calculate the incidence of ectopic pregnancy in cases with recurrent early pregnancy loss and cases of recurrent implantation failure. Methods and materials: This is a retrospective cohort study. 200 women were recruited from the infertility clinic at shat by maternity university hospital seeking fertility. 100 of them were with history of recurrent implantation failure (RIF) and 100 with history of recurrent pregnancy loss (RPL). Revisiting their hospital files for the history of ectopic pregnancy was done. Results: 8% of cases of RPL had history of ectopic pregnancy while only 6% of cases of RIF had the history. There was no significant difference between the two groups (p = 0.579). There was significantly higher incidence of ectopic pregnancy in both groups if compared with the general population (p = 0.0001 and 0.043) in RPL and RIF consecutively. Conclusions: RPL and RIF may be considered as a risk factor for ectopic pregnancy.
文摘<b><span>Background:</span></b><span> The objective of this meta-analysis was to assess whether mini-</span><span>implants </span><span>have</span><span> added benefit in terms of implants success rate and average bone loss over conventional-sized implants after one year of follow-up.</span><span> </span><b><span>Methods: </span></b><span>An electronic search of randomized clinical trials was conducted in MEDLINE (via PubMed), Cochrane Central Register of Clinical Trials (CENTRAL) and Web of Science for studies including complete or partial edentulous patients requiring two or four mini-implants or conventional/</span><span> </span><span>standard-sized implants in the maxilla or mandible for implant-supported removable prostheses who completed 12 months of follow-up. </span><b><span>Results:</span></b><span> The search provided 194 unique articles which were screened for title and abstract. Screening generated 12 articles which went through full-text analysis using eligibility criteria, and 4 articles were included for meta-analysis. Meta-analysis of these studies indicated a non-significant difference in the success rate between the two interventions (OR = 1.69 [0.74, 3.85;p = 0.21]). Bone loss estimates resulted in a significant bone reduction (Mean Difference = </span><span>-</span><span>0.74 [</span><span>-</span><span>0.95, </span><span>-</span><span>0.53;p < 0.05]) in favor of two mini-implants when compared with two conventional-sized implants, but when compared four mini</span><span>- </span><span> </span><span>with two conventional-sized implants</span><span>,</span><span> the estimates were non-significant </span><span>(Mean Difference = </span><span>-</span><span>0.24 [</span><span>-</span><span>0.69, 0.20;p = 0.29]). </span><b><span>Conclusion: </span></b><span>The current evidence does not provide solid evidence of the benefits of one intervention over the other. More studies with follow-up times of 10 and more years are needed as current studies have described the short-term outcomes.</span>
文摘目的探讨肝移植术后植入人工耳蜗的感音神经性耳聋老年患者临床处治特点和注意事项。方法肝移植术后老年患者1例,62岁女性,双耳感音神经性耳聋(全聋)超过10年,肝移植术后长期服用抗排异、激素药物,移植后8年行人工耳蜗植入术。针对患者的特殊病史和身体条件,人工耳蜗植入术后除进行常规开机外,给予肝功能保护、监测他克莫司浓度、感染、心理护理等处治措施。结果肝移植老年患者开机1年8个月后助听听阈≤35 dB HL,单音节识别率70.67%,双音节识别率85%,言语空间音质听力量表(the speech,spatial and qualities of hearing scale,SSQ)得分19分。未见与肝移植相关并发症,术后心理状态明显改善,生活质量显著提高。结论人工耳蜗植入术对肝移植后接受免疫抑制治疗的老年患者是一种安全有效的干预手段。突出抗感染、提升免疫力对确保手术安全性、有效性至关重要。
