Impact of 222-nm ultraviolet disinfection combined with psychological care on the emotional and hospital infection of critical patients

BACKGROUND Empathetic psychological care improves mood and enhances the quality of life in critically ill patients.AIM To study the impact of combining 222-nm ultraviolet(UV)disinfection with empathetic psychological care on emotional states,nosocomial infection rates,and quality of life in critically ill patients.METHODS A total of 202 critically ill patients admitted to Beijing Ditan Hospital(December 2023 to May 2024)were randomly assigned to control(Ctrl,n=101)or observation groups(Obs,n=101).The Ctrl group received 222-nm UV disinfection and routine care,while the Obs group received 222-nm UV disinfection with empathetic psychological care.Emotional states[Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS)],hospital infection rates,quality of life(36-Item Short Form Health Survey),and patient satisfaction were evaluated.RESULTS At baseline,there were no significant differences in SAS and SDS scores between the groups(P>0.05).Following care,both groups demonstrated reductions in SAS and SDS scores,with the Obs group exhibiting a significantly greater reduction(P<0.05).The Obs group also experienced a significantly lower overall hospital infection rate(P<0.05).Similarly,while baseline 36-Item Short Form Health Survey scores did not differ significantly between the groups(P>0.05),post-care scores improved in both groups,with a greater improvement observed in the Obs group(P<0.05).Additionally,the Obs group reported higher patient satisfaction ratings(P<0.05).CONCLUSION The combination of 222-nm UV disinfection and empathetic psychological care improves emotional states,reduces hospital infection rates,enhances the quality of life,and increases patient satisfaction among critically ill patients.

Improving gastrointestinal scoring systems for predicting short-term mortality in critically ill patients

Shen et al’s retrospective study aims to compare the utility of two separate scoring systems for predicting mortality attributable to gastrointestinal(GI)injury in critically ill patients[the GI Dysfunction Score(GIDS)and the Acute Gastroin-testinal Injury(AGI)grade].The authors note that this study is the first proposal that suggests an equivalence between the ability of both scores to predict mor-tality at 28 days from intensive care unit(ICU)admission.Shen et al retrospec-tively analysed an ICU cohort of patients utilising two physicians administering both the AGI grade and GIDS score,using electronic healthcare records and ICU flowsheets.Where these physicians disagreed about the scores,the final decision as to the scores was made by an associate chief physician,or chief physician.We note that the primary reason for the development of GIDS was to create a clear score for GI dysfunction,with minimal subjectivity or inter-operator variability.The subjectivity inherent to the older AGI grading system is what ultimately led to the development of GIDS in 2021.By ensuring consensus between physicians administering the AGI,Shen et al have controlled for one of this grading systems biggest issues.We have concerns,however,that this does not represent the real-world challenges associated with applying the AGI compared to the newer GIDS,and wonder if this arbitration process had not been instituted,would the two scoring systems remain equivalent in terms of predicted mortality?

Identification of patients with advanced pancreatic cancer who might benefit from third-line chemotherapy

BACKGROUND Survival rates of patients with advanced pancreatic cancer(APC)have been improved with palliative chemotherapy series.The current preferred first-line regimen consists of combination therapy of 5-fluorouracil(5-FU)/leucovorin(LV),irinotecan,and oxaliplatin(FOLFIRINOX)or gemcitabine plus albumin-bound paclitaxel(GNP).After failure of first-line chemotherapy,there are a few options for subsequent therapy including switch to the unused first-line regimen or nanoliposomal irinotecan and 5-FU/LV.However,there are limited studies on the efficacy of third-line chemotherapy after failure of second-line chemotherapy.AIM To identify patients with APC who might benefit from third-line chemotherapy.METHODS Medical records from a single tertiary hospital were retrospectively reviewed between 2012 and 2021.The study included patients with histologically or cytologically confirmed metastatic or locally APC who underwent first-line FOLFIRINOX or GNP and subsequently received third-line chemotherapy.Overall survival(OS)after diagnosis and OS after third-line chemotherapy(OS3)were defined as the interval from the diagnosis to all-cause death and the time between the initiation of the third-line chemotherapy to all-cause death,respectively.RESULTS A total of 141 patients were enrolled.The median patient age at diagnosis was 61.8 years(36.0-86.0),and 54.9%were male.The first-line regimen was FOLFIRINOX(67.4%)or GNP(32.6%).The second-line regimen was FOLFIRINOX(27.0%),GNP(52.5%),or other(20.6%).The median OS was 19.0 months,and the median OS3 and progression-free survival after third-line treatment were 15.3 and 7.3 weeks,respectively.With regard to the best tumor response during third-line chemotherapy,1.4%had partial response,24.8%had stable disease,and 59.6%had progressive disease.The following clinical factors before third-line chemotherapy affected OS3:Good performance status(PS),serum carbohydrate antigen 19-9(CA19-9)level<1000 U/mL,duration of second-line chemotherapy≥19 weeks,and no peritoneal seeding.CONCLUSION This study identified that patients with good PS,CA19-9<1000 U/mL,second-line chemotherapy≥19 weeks,and no peritoneal seeding before starting third-line treatment may benefit more from third-line chemotherapy.

基于顶空-固相微萃取-气相色谱-质谱和顶空-气相色谱-离子迁移谱技术结合化学计量法分析芜菁冻干片挥发性成分

为探究不同品种芜菁冻干片中挥发性有机物(volatile organic compounds,VOCs)的差异,采用顶空-固相微萃取-气相色谱-质谱(headspace solid phase microextraction gas chromatography-mass spectrometry,HS-SPME-GC-MS)和顶空-气相色谱-离子迁移谱(headspace gas chromatography-ion mobility spectrometry,HS-GC-IMS)对紫色、黄色和白色3种芜菁冻干片的VOCs进行分析,并结合主成分分析(principal component analysis,PCA)和偏最小二乘判别法(partial least squares-discriminant analysis,PLS-DA)等化学计量法探究不同品种芜菁冻干片挥发性成分的差异。结果表明,通过HS-SPME-GC-MS共解析出96种VOCs,包括醛类、醇类、酮类、含硫化合物、酯类、酸类等化合物,其中含硫化合物和酯类为芜菁冻干片中相对含量最高的化合物种类;HS-GC-IMS共解析出94种VOCs,包括醛类、酯类、酮类及含硫化合物等挥发性成分。HS-SPME-GC-MS和HS-GC-IMS检出的挥发性物质种类和含量存在差异,共有VOCs有15种,二者结果互为补充,结合使用可以较全面系统地表征芜菁冻干片的挥发性成分。PCA和PLS-DA结果表明,2种方法均能够有效区分3种芜菁冻干片。通过变量投影重要度分别筛选了59种和23种差异VOCs,该结果可为芜菁冻干片VOCs的差异分析提供参考方法。

医疗纠纷发生原因分析及对策研究——基于某医院2018-2023年医疗纠纷处理的实践

目的 探讨2018—2023年西安市某三甲综合医院医疗纠纷的现状和原因及对策。方法 收集2018年1月至2023年12月西安市某三甲医院已处理完结的804例医疗纠纷案例,回顾性分析医疗纠纷发生情况、现状特点和原因分布。结果医疗纠纷累计发生率为4.408/10万,赔付率为31.59%(254/804),2018—2023年医疗纠纷发生率和赔付率整体呈逐年增长的趋势(P<0.05);6年纠纷案例中死亡患者占比呈逐年增加的趋势(χ^(2)=30.396,P=0.011),医疗纠纷案例主要来源于住院患者(65.17%)和接受手术治疗的患者(55.35%),发生医疗纠纷案例排名前五位的科室依次为肝胆外科、心血管内科、妇产科、急诊科和消化内科;2018—2023年院内调解逐年降低,而人民调解呈逐年增加趋势(χ^(2)=34.523,P<0.001);该医院医疗纠纷案例的发生原因前五位为:手术/操作并发症(29.10%)、病情评估/疾病诊断(10.45%)、诊疗方案(9.45%)、诊疗效果(8.83%)以及医保报销(7.59%)。结论 综合医院医疗纠纷和赔付案件逐年增加,对于手术科室、急诊科等高风险科室需高度关注;医疗纠纷处理方式展现为多元化,人民调解逐渐占据主导地位;医疗纠纷发生原因主要集中在诊疗技术、医患沟通、医疗保险等方面,需不断提升临床诊疗技术水平,加强医患沟通,完善医疗保障体系,强化医院内涵管理,缓解医患矛盾,构建和谐医患关系。

见光诱导催化合成3,4-二氢异喹啉-1(2H)-酮及其衍生物

建立了一种在温和条件下,用可见光催化合成一系列3,4-二氢异喹啉-1(2H)-酮及其衍生物的方法。该方法在室温条件下,以2-烯丙基-N-甲氧基苯甲酰胺为模板底物,以碘化钾作为光催化剂,25 W 460 nm的蓝色LED灯照射下,合成一系列3,4-二氢异喹啉-1(2H)-酮衍生物,最高产率可达到83%。该合成路径具有底物适用范围广、经济实用等特点,为3,4-二氢异喹啉-1(2H)-酮衍生物合成提供了一种经济简便的方法。

“五闭-五到-心力”教学路径改革探索——以汽车类材料科学基础课程为例

针对学生学情与教材传统内容兼容度低、“五闭”与学习效率低、脆弱知识多与学科思维少的三大教学难点,通过“一体两翼与思政”螯合提出重组教学内容,三大教学理念引领课堂升级,三大教学目标重在因材施教等创新举措;通过信息技术与传统教学深度融合,强化师生互动,优化教学活动,完善考核机制,获得教学目标达成度良好、学生发展态势凸显、教学模式辐射、跟踪学生学习的教改效果。课程构建并实施了打开学生“五闭”,达成“五到-心力”转变,实现沉浸式教学模式,这不仅提升了教学广度与深度,还展示出良好的教学效果,同时还具有迁移应用。

基于CNCSCOLOR的色相-色调感性模型构建

中国应用色彩体系(CNCSCOLOR)基于中国人眼视觉实验所开发,但在国外色彩体系的早期市场占有下没有得到广泛应用。本研究尝试开发一套易于学习推广的模型,以促进其普及和应用。首先通过对三维色彩体系的研究分析,借鉴日本PCCS色彩体系,构建了简化的二维色相-色调基本模型,其中色调融合了色彩属性明度和彩度。模型用直角坐标定位,水平轴为彩度,垂直轴为明度,5种无彩色将明度轴分为四段,12个20色色相环即12种有彩色色调,按照明度与彩度的大小有序分布于平面内。确定构成基本模型的240种有彩色和5种无彩色的选色规则,选出色彩,组合完善基本模型。其次,研究确定12种有彩色色调的感性,得到色相-色调感性模型。通过主观调查初步分析得到有彩色色调的感性,再实施客观眼动实验进一步验证调查结果,最终确定12个有彩色色调的感性分别是鲜明的、明快的、强烈的、浑厚的、清新的、淡雅的、浑浊的、厚重的、浅淡的、暗淡的、灰暗的、黑暗的。研究得到的色相-色调模型包含的色彩数量少,采用二维的平面布局,使初学者易懂易记,便于普及应用;且色调命名符合中国人的情感特征,将用于后续的感性配色模型构建,便于设计师和消费者快速进行精准的产品色彩搭配,对中国本土色彩体系的发展和色彩设计水平的提升具有实际的应用价值。

现代医院管理制度下激励-协调-监督机制应用于医护人员培训管理中的效果分析

目的研究现代医院管理制度下激励-协调-监督机制应用于医护人员培训管理中的效果并进行分析。方法选取2022年2月—2024年2月于医院工作的84例医护人员开展研究。将其按照时间点分作参考组(n=42,2022年2月—2023年2月)及研究组(n=42,2023年3月—2024年2月)。参考组开展常规管理,研究组则开展基于激励-协调-监督机制的管理。对比两组管理质量,不良事件发生情况,管理满意度,核心能力。结果研究组文化建设、奖惩机制、上报制度及沟通协调机制评分均高于参考组(均P<0.05)。研究组不良事件发生率低于参考组(7.14%vs 23.81%)(P<0.05)。研究组管理方式、管理内容、管理形式及沟通技巧满意度分别为95.24%、92.86%、97.62%、95.24%,均高于参考组的78.57%、73.81%、76.19%、73.81%(均P<0.05)。研究组各项核心能力评分均高于参考组(均P<0.05)。结论激励-协调-监督机制应用于医护人员培训管理中的效果较佳,可提高管理质量、管理满意度及核心能力,且能减少不良事件的发生。

Association of cardiometabolic multimorbidity with all-cause and cardiovascular disease mortality among Chinese hypertensive patients

BACKGROUND Hypertension usually clusters with multiple comorbidities.However,the association between cardiometabolic multimorbidity(CMM)and mortality in hypertensive patients is unclear.This study aimed to investigate the association between CMM and all-cause and cardiovascular disease(CVD)mortality in Chinese patients with hypertension.METHODS The data used in this study were from the China National Survey for Determinants of Detection and Treatment Status of Hypertensive Patients with Multiple Risk Factors(CONSIDER),which comprised 5006 participants aged 19–91 years.CMM was defined as the presence of one or more of the following morbidities:diabetes mellitus,dyslipidemia,chronic kidney disease,coronary heart disease,and stroke.Cox proportional hazard models were used to calculate the hazard ratios(HR)with 95%CI to determine the association between the number of CMMs and both all-cause and CVD mortality.RESULTS Among 5006 participants[mean age:58.6±10.4 years,50%women(2509 participants)],76.4%of participants had at least one comorbidity.The mortality rate was 4.57,4.76,8.48,and 16.04 deaths per 1000 person-years in hypertensive patients without any comorbidity and with one,two,and three or more morbidities,respectively.In the fully adjusted model,hypertensive participants with two cardiometabolic diseases(HR=1.52,95%CI:1.09–2.13)and those with three or more cardiometabolic diseases(HR=2.44,95%CI:1.71–3.48)had a significantly elevated risk of all-cause mortality.The findings were similar for CVD mortality but with a greater increase in risk magnitude.CONCLUSIONS In this study,three-fourths of hypertensive patients had CMM.Clustering with two or more comorbidities was associated with a significant increase in the risk of all-cause and cardiovascular mortality among hypertensive patients,suggesting more intensive treatment and control in this high-risk patient group.

The association between C-reactive protein to albumin ratio and 6-month neurological outcome in patients with in-hospital cardiac arrest

The global incidence rates of in-hospital cardiac arrest(IHCA)range from1.2 to 9.0 per1,000 hospitalized patients,as per the National Cardiac Arrest Database.[1] While IHCAs tend to exhibit superior 30-day survival rates relative to out-of-hospital cardiac arrests (OHCA) due to situational advantages,such as immediate access to medical personnel and treatments.

Risk factors for early death in severe non-brain- injured trauma patients

Severe trauma is one of the main causes of premature death,posing a significant challenge to public health systems.[1]At present,there is a lack of universally accepted guidelines for rapid detection of life-threatening severe trauma,[2]and the accuracy of existing prognostic models in predicting early death is limited.[3,4]Severe non-brain-injured trauma(SNT)patients account for approximately 70%of all trauma-related deaths.Moreover,there is a lack of studies on early death in SNT patients.[5]This study aims to identify risk factors associated with early death(≤72 h post-admission)in SNT patients.

Association of prealbumin with short-term and long-term outcomes in patients with acute ST-segment elevation myocardial infarction

BACKGROUND Prealbumin is considered to be a useful indicator of nutritional status. Furthermore, it has been found to be associated with severities and prognosis of a range of diseases. However, limited data on the association of baseline prealbumin level with outcomes of patients with acute ST-segment elevation myocardial infarction(STEMI) are available.METHODS We analyzed 2313 patients admitted for acute STEMI between October 2013 and December 2020. In-hospital outcomes and mortality during the 49 months(interquartile range: 26–73 months) follow-up period were compared between patients with the low prealbumin level(< 170 mg/L) and those with the high prealbumin level(≥ 170 mg/L).RESULTS A total of 114 patients(4.9%) died during hospitalization. After propensity score matching, patients with the low prealbumin level than those with the high prealbumin level experienced higher incidences of heart failure with Killip class Ⅲ(9.9%vs. 4.4%, P = 0.034), cardiovascular death(8.4% vs. 3.4%, P = 0.035) and the composite of major adverse cardiovascular events(19.2%vs. 10.3%, P = 0.012). Multivariate logistic regression analysis identified that the low prealbumin level(< 170 mg/L) was an independent predictor of in-hospital major adverse cardiovascular events(odds ratio = 1.918, 95% CI: 1.250–2.942, P = 0.003). The cutoff value of prealbumin level for predicting in-hospital death was 170 mg/L(area under the curve = 0.703, 95% CI: 0.651–0.754, P< 0.001;sensitivity = 0.544, specificity = 0.794). However, after multivariate adjustment of possible confounders, baseline prealbumin level(170 mg/L) was no longer independently associated with 49-month cardiovascular death. After propensity score matching, Kaplan-Meier survival curves revealed consistent results.CONCLUSIONS Decreased prealbumin level closely related to unfavorable short-term outcomes. However, after multivariate adjustment and controlling for baseline differences, baseline prealbumin level was not independently associated with an increased risk of long-term cardiovascular mortality in STEMI patients.

Refining safety considerations for intradialytic blood flow restriction exercise. Commentary on “Concerns on the application of blood-flow restriction resistance exercise and thrombosis risk in hemodialysis patients”

I read with great interest the article“Concerns on the application of blood flow restriction resistance exercise and thrombosis risk in hemodialysis patients”by Correa et al.1 The study presents complementary data from a previous randomized controlled trial,2 exploring the application of intradialytic blood flow restriction exercise for hemodialysis patients.

ε-聚赖氨酸对苹果灰霉病菌的抑菌机制

为研究ε-聚赖氨酸(ε-PL)对苹果灰霉病菌Botrytis cinerea的抑制效果及其机制。用不同浓度的ε-PL处理B.cinerea,研究其对B.cinerea的菌落直径、孢子萌发、菌丝生长及对苹果灰霉病防治效果的影响,同时考察B.cinerea细胞通透性、抗氧化酶活性、细胞可溶性蛋白与核酸的泄漏、丙二醛含量及活性氧的变化规律。结果表明:ε-PL对B.cinerea的最小抑菌浓度为400 mg/L,该浓度的ε-PL能有效控制苹果灰霉病;100 mg/L以上的ε-PL能显著抑制B.cinerea孢子萌发和菌丝生长(P<0.05),破坏孢子膜结构,增大孢子细胞的通透性,造成可溶性蛋白与核酸发生泄漏,使孢子形态呈现萎缩干瘪、甚至溶解现象;此外,100 mg/L以上的ε-PL能显著降低B.cinerea的超氧化物歧化酶、多酚氧化酶和过氧化氢酶的活性,升高丙二醛含量(P<0.05)。综上,ε-PL能通过破坏B.cinerea孢子细胞膜结构、增大细胞通透性、抑制抗氧化酶活性、促进活性氧的积累,进而增大孢子膜的脂质过氧化程度,损伤孢子结构,最终抑制苹果灰霉病菌的生长。此项研究可为ε-PL在苹果采后病害防治中的应用打下基础,具有较高的应用价值。

基于KY3H中医体质辨识-评估-干预系统辨证治疗先兆流产临床研究

目的:观察在常规治疗基础上基于KY3H中医体质辨识-评估-干预系统辨证治疗先兆流产的临床疗效。方法:选取2022年7月—2023年6月在浙江中医药大学附属温州市中医院治疗的600例先兆流产患者,以随机数字表法分为对照组与观察组各300例。对照组予以常规治疗,观察组在对照组基础上根据体质类型针对性给予中药汤剂治疗。2组均治疗2周。比较2组临床疗效、性激素水平及保胎成功率。结果:治疗2周后,总有效率观察组93.00%(279/300),高于对照组87.67%(263/300),差异有统计学意义(P<0.05)。2组血清孕酮(P)、雌二醇(E2)、人绒毛膜促性腺激素(HCG)水平均较治疗前升高,观察组血清P、E2、HCG水平均高于对照组,差异均有统计学意义(P<0.05)。保胎成功率观察组90.67%(272/300),高于对照组83.67%(251/300),差异有统计学意义(P<0.05)。结论:在常规治疗基础上基于KY3H中医体质辨识-评估-干预系统辨证治疗先兆流产能提高P、E2、HCG水平,改善妊娠结局。

Sleep quality in middle-aged and elderly hemodialysis patients:Impact of a structured nursing intervention program

BACKGROUND Poor sleep quality is common among hemodialysis patients and can significantly impact their well-being.This study aimed to evaluate the effectiveness of a structured nursing intervention program in improving sleep quality in middleaged and elderly hemodialysis patients.AIM To evaluate the impact of nursing intervention on sleep quality in hemodialysis patients.METHODS This cross-sectional study was conducted in a tertiary hospital,the First Affiliated Hospital of Nanchang University,in 2023.This study included 105 middle-aged and elderly hemodialysis patients aged≥45 years who underwent maintenance hemodialysis for at least 3 mo,utilizing the Pittsburgh Sleep Quality Index(PSQI)to identify poor sleepers.Those identified underwent a 12-wk nursing intervention program focusing on education,relaxation techniques,and counseling.Post-intervention,sleep quality was reassessed using the PSQI.RESULTS The study found that 68.6%of hemodialysis patients were poor sleepers.Following the 12-wk nursing intervention program,there was a significant decrease in the mean global PSQI score from 8.9±3.2 to 5.1±2.7(P<0.001),indicating improved sleep quality.This demonstrated the effectiveness of the structured nursing intervention in enhancing sleep quality for middle-aged and elderly hemodialysis patients.CONCLUSION The structured nursing intervention program focusing on sleep hygiene education,relaxation techniques,and counseling effectively improved sleep quality among middle-aged and elderly hemodialysis patients.The significant decrease in the mean global PSQI score post-intervention indicates the positive impact of tailored nursing interventions in addressing poor sleep quality in this patient population.These findings emphasize the importance of implementing targeted nursing interventions to enhance the quality of life for hemodialysis patients by addressing the prevalent issue of poor sleep quality.

基于船舶-流场运动耦合的内河航道设计方法

航道一般指江河及运河内可供船舶通航的水域,目前大多采用流场演化规律分析结合工程人员经验的方法开展规划设计,对通行船舶这一因素考虑不够全面.拟从河道中船舶与流场直接作用的角度提出一种内河航道设计方法.首先,基于Fluent二次开发,突破了船舶-流场相互作用的水动力响应解耦算法,对内河航段中船舶自由漂流运动进行模拟,其中,流场使用有限体积法进行求解,船舶运动控制方程通过用户自定义模块(UDF)输入并采用四阶Runge-Kutta法求解,动网格技术用于更新计算域;然后,考虑航行频率,给予通行船型不同权重,使用加权最小二乘法对漂流轨迹进行曲线拟合,得到航道边界线.选取了长江东流(从天生洲起)这一具有典型碍航结构物(弯道、分汊)航段开展航道设计验证.研究结果表明:设计的航道与现行规划航道趋势一致;同时,结合流场细节云图对船舶运动响应过程进行分析,发现设计的航道可使船舶有效规避风险急流、斜流,合理利用水流动能,提升航行安全性和经济性.

Patient satisfaction and follow-up adherence to glaucoma case management clinic in China

AIM:To assess glaucoma patient satisfaction and follow-up adherence in case management and identify associated predictors to improve healthcare quality and patient outcomes.METHODS:In this cross-sectional study,a total of 119 patients completed a Patient Satisfaction Questionnaire-18 and a sociodemographic questionnaire.Clinical data was obtained from the case management system.Follow-up adherence was defined as completing each follow-up within±30d of the scheduled time set by ophthalmologists during the study period.RESULTS:Average satisfaction scored 78.65±7,with an average of 4.39±0.58 across the seven dimensions.Age negatively correlated with satisfaction(P=0.008),whilst patients with follow-up duration of 2 or more years reported higher satisfaction(P=0.045).Multivariate logistics regression analysis revealed that longer follow-up durations were associated with lower follow-up adherence(OR=0.97,95%CI,0.95-1.00,P=0.044).Additionally,patients with suspected glaucoma(OR=2.72,95%CI,1.03-7.20,P=0.044)and those with an annual income over 100000 Chinese yuan demonstrated higher adherence(OR=5.57,95%CI,1.00-30.89,P=0.049).CONCLUSION:The case management model proves effective for glaucoma patients,with positive adherence rates.The implementation of this model can be optimized in the future based on the identified factors and extended to glaucoma patients in more hospitals.

四川盆地南缘二叠系茅口组构造-沉积分异及控储效应

四川盆地作为中国海相碳酸盐岩油气的主力产区,在盆地震旦系、寒武系和二叠系发现多个大型油气聚集带。与蕴含巨量油气的二叠系长兴组礁滩相储层相比,二叠系茅口组碳酸盐岩储层以往一直被认为是裂缝、缝洞型储层,油气勘探未取得重大突破。最近,在川中地区茅口组台缘相带显示具有良好白云岩储层,其形成背景与基底断裂活化导致构造-沉积分异密切相关。川南地区在茅口期亦发生基底断裂活动,但对于该地区是否发育类似的台缘相带仍不明确。通过开展详细的野外露头和钻井资料分析,开展了构造-沉积分异和岩相古地理重建研究。结果表明,川南地区茅口组发育碳酸盐开阔台地、台地边缘和深水陆棚相,具有由浅水台缘滩向深水陆棚转换形成的构造-沉积分异结构。岩相古地理重建结果显示中二叠世茅口组沉积期碳酸盐台地发育优质滩相储层,并受白云石化和溶蚀作用改造。在此基础上,建立了川南地区的构造-沉积分异控储模式,揭示了台缘相带的“宽边缘、薄滩体、间断加积”特性。