A total of 103 surface sediment samples collected from the water depth range of 15-3300 m along Vijaydurg-Karwar stretch of central west coast of India were analyzed for foraminiferal content. Relict benthic foraminif...A total of 103 surface sediment samples collected from the water depth range of 15-3300 m along Vijaydurg-Karwar stretch of central west coast of India were analyzed for foraminiferal content. Relict benthic foraminiferal assemblage was noted within 50--135 m water depth. The relict benthic foraminiferal assemblage that includes Amphistegina, Operculina and Alveolinella in sediment samples within the water depth of 85-- 135 m indicates presence of coral reef at this depth during Early Holocene. The presence of barnacle fouling on Relict foraminifera at 60--90 m confirms the paleo-shoreline. The shallow depth zone is characterized by presence of agglutinated relict foraminifera. The agglutinated forms indicate freshwater influx, which eventually increased the sea level and subsequently deteriorated the paleo-coral reef.展开更多
There is rising incidence and prevalence of inflammatory bowel disease(IBD) in India topping the Southeast Asian(SEA) countries. The common genes implicated in disease pathogenesis in the West are not causal in Indian...There is rising incidence and prevalence of inflammatory bowel disease(IBD) in India topping the Southeast Asian(SEA) countries. The common genes implicated in disease pathogenesis in the West are not causal in Indian patients and the role of "hygiene hypothesis" is unclear. There appears to be a North-South divide with more ulcerative colitis(UC) in north and Crohn's disease(CD) in south India. IBD in second generation Indian migrants to the West takes the early onset and more severe form of the West whereas it retains the nature of its country of origin in migrants to SEA countries. The clinical presentation is much like other SEA countries(similar age and sex profile, low positive family history and effect of smoking, roughly similar disease location, use of aminosalicylates for CD, low use of biologics and similar surgical rates) with some differences(higher incidence of inflammatory CD, lower perianal disease, higher use of aminosalicylates and azathioprine and lower current use of corticosteroids). UC presents more with extensive disease not paralleled in severity clinically or histologically, follows benign course with easy medical control and low incidence of fulminant disease, cancer, complications, and surgery. UC related colorectal cancer develop in an unpredictable manner with respect to disease duration and site questioning the validity of strict screening protocol. About a third of CD patients get antituberculosis drugs and a significant number presents with small intestinal bleed which is predominantly afflicted by aggressive inflammation. Biomarkers have inadequate diagnostic sensitivity and specificity for both. Pediatric IBD tends to be more severe than adult. Population based studies are needed to address the lacunae in epidemiology and definition of etiological factors. Newer biomarkers and advanced diagnostic techniques(in the field of gastrointestinal endoscopy, molecular pathology and genetics) needs to be developed for proper disease definition and treatment.展开更多
Due to global climate warming and natural and man-made land subsidence etc., relative sea level rise in the coastal plains of China will exceed 2-3 times over the golbal mean value during the first half part of the 21...Due to global climate warming and natural and man-made land subsidence etc., relative sea level rise in the coastal plains of China will exceed 2-3 times over the golbal mean value during the first half part of the 21st century. It will result in a series of adverse impacts on evolution of natural environment and socioeconomic development of the coastal area. This paper analyses environmental and resource effects induced by relative sea level rise in China's coastal areas on the basis of rough estimate of future relative sea level rise. These effects include inundating tidal flat and wetlands and increase in inundated risk of coastal habitable land,exacerbating storm surge. coastal erosion, flooding and salt water intrusion hazards.as well as endangering land. water. tourism and living resources and their utilization.展开更多
The East Pacific Rise(EPR)is a typical fast spreading ridge.To gain a better understanding of the magmatism under ridges,Mid Ocean Ridge Basalts(MORBs)with remarkably heterogeneous compositions are obtained from(EPR)1...The East Pacific Rise(EPR)is a typical fast spreading ridge.To gain a better understanding of the magmatism under ridges,Mid Ocean Ridge Basalts(MORBs)with remarkably heterogeneous compositions are obtained from(EPR)1?–2?S and multielement geochemical and radioisotope analyses are conducted.Results show that these MORBs have wide variation ranges in trace element concentrations and isotopic ratios.Sample 07 has low concentrations of incompatible elements,and very low ^(87)Sr/^(86)Sr,and high ^(143)Nd/^(144)Nd from 0.70213 to 0.702289 and 0.513234 to 0.513289,respectively.However,other samples show enrichment in incompatible elements to varying degrees,and medium values of ^(87)Sr/^(86)Sr and ^(143)Nd/^(144)Nd from 0.702440 to 0.702680 and 0.513086to 0.513200,respectively.This study proposes that one depleted source and two enriched sources contribute to the formation of MORBs from EPR 1?–2?S.Samples 02 and 10 are formed by mixing between one enriched source and one depleted source,while sample 07 is crystallized from the depleted source with no mixing process involved.However,the formation of samples 06 and 11are different,and thus further research is required to determine genesis.展开更多
AIM: To estimate the frequency of microdeletions in the long arm of Y-chromosome of 20 infertile males from South India. METHODS: Polymerase chain reaction (PCR) amplification using Y-specific STS of azoospermia facto...AIM: To estimate the frequency of microdeletions in the long arm of Y-chromosome of 20 infertile males from South India. METHODS: Polymerase chain reaction (PCR) amplification using Y-specific STS of azoospermia factor (AZF) regions i.e., SY 84 for AZFa, SY 127 for AZFb and SY 254 for AZFc. RESULTS: Of the 20 infertile subjects 3 (15 %), one azoospermic and two oligozoospermic, showed microdeletions in the AZF region of Y-chromosome. CONCLUSION: The frequency of deletions involving AZF region of the Y-chromosome is 15 % in azoospermic and severely oligozoospermic infertile men. PCR amplification of AZF locus is useful for the diagnosis of microdeletions in the Y-chromosome.展开更多
According to the space-geodetic data recorded at globally distributed stations over solid land spanning a period of more than 20-years under the International Terrestrial Reference Frame 2008,our previous estimate of ...According to the space-geodetic data recorded at globally distributed stations over solid land spanning a period of more than 20-years under the International Terrestrial Reference Frame 2008,our previous estimate of the average-weighted vertical variation of the Earth's solid surface suggests that the Earth's solid part is expanding at a rate of 0.24 ± 0.05 mm/a in recent two decades.In another aspect,the satellite altimetry observations spanning recent two decades demonstrate the sea level rise(SLR) rate 3.2 ± 0.4 mm/a,of which1.8 ± 0.5 mm/a is contributed by the ice melting over land.This study shows that the oceanic thermal expansion is 1.0 ± 0.1 mm/a due to the temperature increase in recent half century,which coincides with the estimate provided by previous authors.The SLR observation by altimetry is not balanced by the ice melting and thermal expansion,which is an open problem before this study.However,in this study we infer that the oceanic part of the Earth is expanding at a rate about 0.4 mm/a.Combining the expansion rates of land part and oceanic part,we conclude that the Earth is expanding at a rate of 0.35 ± 0.47 mm/a in recent two decades.If the Earth expands at this rate,then the altimetry-observed SLR can be well explained.展开更多
Located in the central Asia, ancient Loullan Town was a place of strategic importance to the ancient SilkRoad. According to the historical records, it was flourishing during the period from the second century B. C. to...Located in the central Asia, ancient Loullan Town was a place of strategic importance to the ancient SilkRoad. According to the historical records, it was flourishing during the period from the second century B. C. to the thirdcentury A. D. However, it was disrecorded suddenly 1400 years ago. Until 1900 it was discovered by a Swedish exploration party. The ruins of Loulan is situated on the west bank of Lop Nur Lake and the delta of the Tarim River (40°29’55’’N, 89°55’22"E), and occupies an area of 108 240 m2. Two main tributaries of the Tarim River passed by its northernand southern sides respectively and converged into Lop Nur Lake about 100 km eastward. Human civilization of the Loulan Town had been developed in the Stone Age, which was revealed by a lot of stone implements found in the ration, andthe discovery of the corpse of "Loulan Beauty" proved the continuity of economic development. During several centuriesaround the Christian era, Loulan had become a place of strategic importance on the Silk Road because its superior geographical position and natural conditions. The decline of ancient Loulan Town was caused by natural change of the rivercourses and rapid environmental deterioration.展开更多
The triple A or AIIgrove's syndrome is an autosomal recessive disorder characterized by the triad of achalasia cardia, alacrima and ACTH resistant adrenocortical insufficiency. Mutations of the Achalasia-Addisonianis...The triple A or AIIgrove's syndrome is an autosomal recessive disorder characterized by the triad of achalasia cardia, alacrima and ACTH resistant adrenocortical insufficiency. Mutations of the Achalasia-AddisonianismAlacrima-Syndrome (AAAS) gene on chromosome 12q13 are associated with this syndrome. We report an Indian family where two siblings were homozygous for a known mutation of the AAAS gene and presented with the classical triad of symptoms. The mother and the brother were heterozygous and asymptomatic. The affected siblings had iron deficiency anemia and the younger sister had pes cavus and palmoplantar keratosis. Neurological symptoms were absent in both affected children. Recognition of this syndrome can lead to early treatment of adrenal insufficency and genetic counselling.展开更多
The consumption in China is surging and Chinese consumers are more confident about their future this year despite the inflationary backdrop, according to the 2011 Annual Chinese Consumer Study by McKinsey & Co rel...The consumption in China is surging and Chinese consumers are more confident about their future this year despite the inflationary backdrop, according to the 2011 Annual Chinese Consumer Study by McKinsey & Co released recently. The survey estimates展开更多
China’s rise has stirred up world-wide debate.In Australia,China has been one of the keywords in its foreign and strategic policies and on news media.Its rise intensifies the dual functions―benefit provider and secu...China’s rise has stirred up world-wide debate.In Australia,China has been one of the keywords in its foreign and strategic policies and on news media.Its rise intensifies the dual functions―benefit provider and security offender to Australia and the tensions between greed of economic gains and fear of China’s increasing geopolitical strength and influence.The“fear and greed”narration is well-presented on Australian mainstream media.Such ambivalence can also find its expressions in the recent typical case of China’s rise―the Belt and Road Initiative.It is worthwhile to find out how Australia’s ambivalence to BRI and China’s rise is represented on media and to draw the sociopolitical inferences behind“fear and greed”.The thesis is going to take BRI as a typical example of China’s rise to examine the ambivalent“fear and greed”narration on Australian mainstream news media.Data sample includes news reports of BRI from ABC News,The Australian,The Australian Financial Review,The Sydney Morning Herald,and The Age from September 1st,2013 to October 31st,2017.The discourse analysis on China’s images finds that Australia is rather biased against China,regarding China both as a lucrative friend and a threatening enemy.The bias lingers on for centuries and generates misunderstanding,mistrust,and anxiety.Profit drives Australia to establish closer economic ties with China,while value differences would not allow too much proximity but help to maintain a robust alliance with its allies.Australia’s position between its major economic partner and traditional allies has caused much concern and will have a long-term influence on its policy-making decisions.展开更多
An innate sensitivity to and phobia of China’s rise seem to have gripped someWestern observers for years.Early back in the 19th century,Napoleon warned the West to“let Chinasleep”.“There lies a sleeping giant,”be...An innate sensitivity to and phobia of China’s rise seem to have gripped someWestern observers for years.Early back in the 19th century,Napoleon warned the West to“let Chinasleep”.“There lies a sleeping giant,”begins his well-known remark.“Let hersleep.For when she wakes,she will shake the world.”In the 1990s,these展开更多
Since Modi took office as Indian prime minister in 2014,India has quickened its pace toward great power status.Although the Indian government did not issue relevant documents and did not systematically give official s...Since Modi took office as Indian prime minister in 2014,India has quickened its pace toward great power status.Although the Indian government did not issue relevant documents and did not systematically give official statements,from the perspective of Modi’s domestic and foreign policies the outline of its strategy of rising as a great power展开更多
ZTE Corporation posted its sales and earningsfor the first quarter on April 23.From January toMarch of this year,its main business revenueincreased 74.67% over the same period last yearto RMB 3.788 billion yuan.The ne...ZTE Corporation posted its sales and earningsfor the first quarter on April 23.From January toMarch of this year,its main business revenueincreased 74.67% over the same period last yearto RMB 3.788 billion yuan.The net profit for theJanuary-March quarter rose to RMB 132.01million yuan versus RMB 88.62 million yuan in theyear-earlier period.Its earnings per sharereached RMB 0.198 yuan.ZTE’s first-quarter growth is encouraging asthe quarter is always a slow season for sales of展开更多
In 1978,China began to open its door to the outside world.After three decades of step-by-step reform,the country has developed into the world's fourth largest economy with a growth rate continuing in the double di...In 1978,China began to open its door to the outside world.After three decades of step-by-step reform,the country has developed into the world's fourth largest economy with a growth rate continuing in the double digits.What has been the nature of China's reform? What achievements have been made? In this article,the author takes an in-depth look at these questions,delivering an analysis of China's 30-year transformation.展开更多
China’s foreign oil dependency level reached 64.4percent of total demand in 2016,3.8 percent higher than the previous year,and was expected to rise again in 2017,according to a leading economic think tank in China.Th...China’s foreign oil dependency level reached 64.4percent of total demand in 2016,3.8 percent higher than the previous year,and was expected to rise again in 2017,according to a leading economic think tank in China.The mainland’s domestic crude production dropped to 200million metric tons in 2016 due to high production costs of domestic crude oil at an average of US$45-50 per barrel,展开更多
文摘A total of 103 surface sediment samples collected from the water depth range of 15-3300 m along Vijaydurg-Karwar stretch of central west coast of India were analyzed for foraminiferal content. Relict benthic foraminiferal assemblage was noted within 50--135 m water depth. The relict benthic foraminiferal assemblage that includes Amphistegina, Operculina and Alveolinella in sediment samples within the water depth of 85-- 135 m indicates presence of coral reef at this depth during Early Holocene. The presence of barnacle fouling on Relict foraminifera at 60--90 m confirms the paleo-shoreline. The shallow depth zone is characterized by presence of agglutinated relict foraminifera. The agglutinated forms indicate freshwater influx, which eventually increased the sea level and subsequently deteriorated the paleo-coral reef.
文摘There is rising incidence and prevalence of inflammatory bowel disease(IBD) in India topping the Southeast Asian(SEA) countries. The common genes implicated in disease pathogenesis in the West are not causal in Indian patients and the role of "hygiene hypothesis" is unclear. There appears to be a North-South divide with more ulcerative colitis(UC) in north and Crohn's disease(CD) in south India. IBD in second generation Indian migrants to the West takes the early onset and more severe form of the West whereas it retains the nature of its country of origin in migrants to SEA countries. The clinical presentation is much like other SEA countries(similar age and sex profile, low positive family history and effect of smoking, roughly similar disease location, use of aminosalicylates for CD, low use of biologics and similar surgical rates) with some differences(higher incidence of inflammatory CD, lower perianal disease, higher use of aminosalicylates and azathioprine and lower current use of corticosteroids). UC presents more with extensive disease not paralleled in severity clinically or histologically, follows benign course with easy medical control and low incidence of fulminant disease, cancer, complications, and surgery. UC related colorectal cancer develop in an unpredictable manner with respect to disease duration and site questioning the validity of strict screening protocol. About a third of CD patients get antituberculosis drugs and a significant number presents with small intestinal bleed which is predominantly afflicted by aggressive inflammation. Biomarkers have inadequate diagnostic sensitivity and specificity for both. Pediatric IBD tends to be more severe than adult. Population based studies are needed to address the lacunae in epidemiology and definition of etiological factors. Newer biomarkers and advanced diagnostic techniques(in the field of gastrointestinal endoscopy, molecular pathology and genetics) needs to be developed for proper disease definition and treatment.
文摘Due to global climate warming and natural and man-made land subsidence etc., relative sea level rise in the coastal plains of China will exceed 2-3 times over the golbal mean value during the first half part of the 21st century. It will result in a series of adverse impacts on evolution of natural environment and socioeconomic development of the coastal area. This paper analyses environmental and resource effects induced by relative sea level rise in China's coastal areas on the basis of rough estimate of future relative sea level rise. These effects include inundating tidal flat and wetlands and increase in inundated risk of coastal habitable land,exacerbating storm surge. coastal erosion, flooding and salt water intrusion hazards.as well as endangering land. water. tourism and living resources and their utilization.
基金supported by the Special and Frontier Foundation for the Twelve Five Plan of the China Ocean Mineral Resources Research and Development Association (Nos.DY125-22-QY-21 and DY125-12-R-02)
文摘The East Pacific Rise(EPR)is a typical fast spreading ridge.To gain a better understanding of the magmatism under ridges,Mid Ocean Ridge Basalts(MORBs)with remarkably heterogeneous compositions are obtained from(EPR)1?–2?S and multielement geochemical and radioisotope analyses are conducted.Results show that these MORBs have wide variation ranges in trace element concentrations and isotopic ratios.Sample 07 has low concentrations of incompatible elements,and very low ^(87)Sr/^(86)Sr,and high ^(143)Nd/^(144)Nd from 0.70213 to 0.702289 and 0.513234 to 0.513289,respectively.However,other samples show enrichment in incompatible elements to varying degrees,and medium values of ^(87)Sr/^(86)Sr and ^(143)Nd/^(144)Nd from 0.702440 to 0.702680 and 0.513086to 0.513200,respectively.This study proposes that one depleted source and two enriched sources contribute to the formation of MORBs from EPR 1?–2?S.Samples 02 and 10 are formed by mixing between one enriched source and one depleted source,while sample 07 is crystallized from the depleted source with no mixing process involved.However,the formation of samples 06 and 11are different,and thus further research is required to determine genesis.
文摘AIM: To estimate the frequency of microdeletions in the long arm of Y-chromosome of 20 infertile males from South India. METHODS: Polymerase chain reaction (PCR) amplification using Y-specific STS of azoospermia factor (AZF) regions i.e., SY 84 for AZFa, SY 127 for AZFb and SY 254 for AZFc. RESULTS: Of the 20 infertile subjects 3 (15 %), one azoospermic and two oligozoospermic, showed microdeletions in the AZF region of Y-chromosome. CONCLUSION: The frequency of deletions involving AZF region of the Y-chromosome is 15 % in azoospermic and severely oligozoospermic infertile men. PCR amplification of AZF locus is useful for the diagnosis of microdeletions in the Y-chromosome.
基金supported by National 973 Project China(2013CB733305,2013CB733301)National Natural Science Foundation of China(41174011,41429401,41210006,41128003,41021061)
文摘According to the space-geodetic data recorded at globally distributed stations over solid land spanning a period of more than 20-years under the International Terrestrial Reference Frame 2008,our previous estimate of the average-weighted vertical variation of the Earth's solid surface suggests that the Earth's solid part is expanding at a rate of 0.24 ± 0.05 mm/a in recent two decades.In another aspect,the satellite altimetry observations spanning recent two decades demonstrate the sea level rise(SLR) rate 3.2 ± 0.4 mm/a,of which1.8 ± 0.5 mm/a is contributed by the ice melting over land.This study shows that the oceanic thermal expansion is 1.0 ± 0.1 mm/a due to the temperature increase in recent half century,which coincides with the estimate provided by previous authors.The SLR observation by altimetry is not balanced by the ice melting and thermal expansion,which is an open problem before this study.However,in this study we infer that the oceanic part of the Earth is expanding at a rate about 0.4 mm/a.Combining the expansion rates of land part and oceanic part,we conclude that the Earth is expanding at a rate of 0.35 ± 0.47 mm/a in recent two decades.If the Earth expands at this rate,then the altimetry-observed SLR can be well explained.
文摘Located in the central Asia, ancient Loullan Town was a place of strategic importance to the ancient SilkRoad. According to the historical records, it was flourishing during the period from the second century B. C. to the thirdcentury A. D. However, it was disrecorded suddenly 1400 years ago. Until 1900 it was discovered by a Swedish exploration party. The ruins of Loulan is situated on the west bank of Lop Nur Lake and the delta of the Tarim River (40°29’55’’N, 89°55’22"E), and occupies an area of 108 240 m2. Two main tributaries of the Tarim River passed by its northernand southern sides respectively and converged into Lop Nur Lake about 100 km eastward. Human civilization of the Loulan Town had been developed in the Stone Age, which was revealed by a lot of stone implements found in the ration, andthe discovery of the corpse of "Loulan Beauty" proved the continuity of economic development. During several centuriesaround the Christian era, Loulan had become a place of strategic importance on the Silk Road because its superior geographical position and natural conditions. The decline of ancient Loulan Town was caused by natural change of the rivercourses and rapid environmental deterioration.
文摘The triple A or AIIgrove's syndrome is an autosomal recessive disorder characterized by the triad of achalasia cardia, alacrima and ACTH resistant adrenocortical insufficiency. Mutations of the Achalasia-AddisonianismAlacrima-Syndrome (AAAS) gene on chromosome 12q13 are associated with this syndrome. We report an Indian family where two siblings were homozygous for a known mutation of the AAAS gene and presented with the classical triad of symptoms. The mother and the brother were heterozygous and asymptomatic. The affected siblings had iron deficiency anemia and the younger sister had pes cavus and palmoplantar keratosis. Neurological symptoms were absent in both affected children. Recognition of this syndrome can lead to early treatment of adrenal insufficency and genetic counselling.
文摘The consumption in China is surging and Chinese consumers are more confident about their future this year despite the inflationary backdrop, according to the 2011 Annual Chinese Consumer Study by McKinsey & Co released recently. The survey estimates
文摘China’s rise has stirred up world-wide debate.In Australia,China has been one of the keywords in its foreign and strategic policies and on news media.Its rise intensifies the dual functions―benefit provider and security offender to Australia and the tensions between greed of economic gains and fear of China’s increasing geopolitical strength and influence.The“fear and greed”narration is well-presented on Australian mainstream media.Such ambivalence can also find its expressions in the recent typical case of China’s rise―the Belt and Road Initiative.It is worthwhile to find out how Australia’s ambivalence to BRI and China’s rise is represented on media and to draw the sociopolitical inferences behind“fear and greed”.The thesis is going to take BRI as a typical example of China’s rise to examine the ambivalent“fear and greed”narration on Australian mainstream news media.Data sample includes news reports of BRI from ABC News,The Australian,The Australian Financial Review,The Sydney Morning Herald,and The Age from September 1st,2013 to October 31st,2017.The discourse analysis on China’s images finds that Australia is rather biased against China,regarding China both as a lucrative friend and a threatening enemy.The bias lingers on for centuries and generates misunderstanding,mistrust,and anxiety.Profit drives Australia to establish closer economic ties with China,while value differences would not allow too much proximity but help to maintain a robust alliance with its allies.Australia’s position between its major economic partner and traditional allies has caused much concern and will have a long-term influence on its policy-making decisions.
文摘An innate sensitivity to and phobia of China’s rise seem to have gripped someWestern observers for years.Early back in the 19th century,Napoleon warned the West to“let Chinasleep”.“There lies a sleeping giant,”begins his well-known remark.“Let hersleep.For when she wakes,she will shake the world.”In the 1990s,these
文摘Since Modi took office as Indian prime minister in 2014,India has quickened its pace toward great power status.Although the Indian government did not issue relevant documents and did not systematically give official statements,from the perspective of Modi’s domestic and foreign policies the outline of its strategy of rising as a great power
文摘ZTE Corporation posted its sales and earningsfor the first quarter on April 23.From January toMarch of this year,its main business revenueincreased 74.67% over the same period last yearto RMB 3.788 billion yuan.The net profit for theJanuary-March quarter rose to RMB 132.01million yuan versus RMB 88.62 million yuan in theyear-earlier period.Its earnings per sharereached RMB 0.198 yuan.ZTE’s first-quarter growth is encouraging asthe quarter is always a slow season for sales of
文摘In 1978,China began to open its door to the outside world.After three decades of step-by-step reform,the country has developed into the world's fourth largest economy with a growth rate continuing in the double digits.What has been the nature of China's reform? What achievements have been made? In this article,the author takes an in-depth look at these questions,delivering an analysis of China's 30-year transformation.
文摘China’s foreign oil dependency level reached 64.4percent of total demand in 2016,3.8 percent higher than the previous year,and was expected to rise again in 2017,according to a leading economic think tank in China.The mainland’s domestic crude production dropped to 200million metric tons in 2016 due to high production costs of domestic crude oil at an average of US$45-50 per barrel,