Introduction: Urinary tract infection is one of the most frequent public health problems in the world and concerns all ages. Objective: To describe the epidemiological, clinical and biological profile of urinary tract...Introduction: Urinary tract infection is one of the most frequent public health problems in the world and concerns all ages. Objective: To describe the epidemiological, clinical and biological profile of urinary tract infection in the internal medicine unit of the Fousseyni Daou hospital in Kayes. Methodology: It was a descriptive and cross-sectional study with retrospective data collection which took place from January 1 to December 31, 2020 at the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes. It covered all outpatients and hospitalized patients presenting with a urinary tract infection during the study period. Results: We identified 79 cases of urinary tract infection out of 145 requests for ECBU, that is a positivity rate of 53.10% and out of a total of 1883 admissions that is a hospital prevalence of 4.19%. The age groups of 36 to 45 years and 46 to 55 years were more represented in 28 cases (35.44%) and 25 cases (31.64%) with an average age of 45 years ± 10. The female sex was predominant, 42 cases (53.16%) with a sex ratio of 0.88. Housewives were more represented 28 cases (34.44%). The majority of patients resided in rural areas 49 cases (62.03%). The history was dominated by the following pathologies: hypertension 48.10%, diabetes 36.70% and gastropathy 30.37%. The main clinical manifestations were: Urinary burning 67 cases (84.81%), Dysuria 65 cases (82.27%), Pelvic pain 59 cases (74.68%), Fever 57 cases (72.15%). The epidemiological profile of the isolated strains was dominated by enterobacteriaceae, followed by gram-positive cocci and gram-negative bacilli. The main bacteria responsible for urinary tract infections in order of frequency: Escherichia coli (45.56%), Klebsiella pneumoniae (11.39%), Pseudomonas aeruginosa (8.86%), Staphylococcus aureus (7.59%), Streptococcus sp (6.33%), Enterobacter cloacae (3.79%), Acinetobacter sp (3.79%). The study of the susceptibility and resistance profiles of the isolated strains showed significant sensitivity of enterobacteriaceae to colistin and resistance to amoxicillin and to the amoxicillin + clavulanic acid combination. Conclusion: Urinary tract infections are a major public health problem since they are responsible for significant morbidity and mortality and a high cost of care. Knowledge of the epidemiological-clinical and bacteriological profile of these infections is essential for efficient management.展开更多
<strong>Introduction:</strong> Urinary tract infections (UTI) are frequent and of polymorphous clinical symptomatology in elderly subjects both in and out of hospital. In Mali, to our knowledge, no study c...<strong>Introduction:</strong> Urinary tract infections (UTI) are frequent and of polymorphous clinical symptomatology in elderly subjects both in and out of hospital. In Mali, to our knowledge, no study concerning UTIs in the elderly has been conducted, hence the interest in this innovative work. <strong>Objectives:</strong> To determine the prevalence and clinical and paraclinical aspects of urinary tract infections in the elderly. <strong>Materials and Methods:</strong> This was a prospective descriptive and cross-sectional study from September 1, 2013 to August 31, 2014, <i>i.e. </i> duration of 12 months. All patients aged 65 years and over, hospitalized or ambulatory in the internal medicine department with a documented urinary tract infection were included. <strong>Results:</strong> We collected and examined 194 patients. The cytobacteriological study of urine (CBSU) was positive in 28 patients, <i>i.e. </i> a prevalence of 14.43%. The male sex represented 59.8% of the cases, the sex ratio was equal to 1.46. The age groups between 65 - 69 and 70 - 74 years were the most affected, respectively 28.57% and 39.28%. The main clinical signs were: asthenia, anorexia, dependence, fever, urinary burning, dysuria. Hospitalization was associated with urinary tract infection with P = 0.01. The group of enterobacteria were incriminated in 75% of cases. <i>Escherichia coli, Klebsiella pneumoniae</i> and <i>Pseudomonas aeruginosa</i> represented 39.28%, 14.28% and 10.71% of cases. Urinary tract infections were represented by pyelonephritis, acute prostatitis, orchi-epididymitis and simple cystitis. <strong>Conclusion:</strong> Urinary tract infection is frequent in the elderly, its clinical presentation is polymorphic and enterobacteria are the most incriminated group of bacteria.展开更多
目的探讨多模态影像融合(multimodal image fusion,MMIF)辅助以案例为基础的教学法(case based learning,CBL)对心血管内科住院医师规范化培训(简称住培)效果的影响。方法选择2021年10月—2022年10月在南京医科大学第一附属医院心血管...目的探讨多模态影像融合(multimodal image fusion,MMIF)辅助以案例为基础的教学法(case based learning,CBL)对心血管内科住院医师规范化培训(简称住培)效果的影响。方法选择2021年10月—2022年10月在南京医科大学第一附属医院心血管内科轮转的住院医师为研究对象,共60名。根据不同轮转时间将2021年10月—2022年3月进行轮转医师设为对照组,共27名;将2022年4月—2022年10月进行轮转的医师设为观察组,共33名。对照组予以常规教学模式,观察组行MMIF辅助CBL教学法,2组教学均持续2个月。于教学前后,评估2组的理论知识、实践能力、自主学习能力和临床思维能力;评估2组医师的教学满意度。结果观察组满意度高于对照组(96.67%vs.77.78%),差异有统计学意义(P<0.05)。带教后,2组理论知识、实践能力评分、自主学习能力和临床思维能力评分均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。结论MMIF辅助CBL教学法在心血管内科住培中的效果较好,可提高学员的理论成绩、实践能力和自主学习能力,培养其临床思维能力。展开更多
探究以问题为基础的学习(problem based leaming,PBL)联合微信视频教学模式在急诊内科临床带教中的应用效果。选取2022年1月—2023年1月广东医科大学附属第二医院急诊内科的60名临床实习生作为研究对象,随机将其分为对照组(常规带教模式...探究以问题为基础的学习(problem based leaming,PBL)联合微信视频教学模式在急诊内科临床带教中的应用效果。选取2022年1月—2023年1月广东医科大学附属第二医院急诊内科的60名临床实习生作为研究对象,随机将其分为对照组(常规带教模式)和观察组(PBL联合微信视频教学模式),每组各30名。对比两组实习生的临床带教效果。结果显示,观察组各项考核成绩(理论知识、操作技能、综合病例分析)高于对照组(P<0.05);观察组各维度综合能力评分(病历书写、体格检查、临床判断、沟通技能、团队协作)高于对照组(P<0.05);观察组各项自我评价指标均优于对照组(P<0.05);观察组各维度职业认同感评分及总分高于对照组(P<0.05);观察组带教满意度高于对照组(P<0.05)。研究发现,在急诊内科临床带教中应用PBL联合微信视频教学模式,可起到提升实习生的考核成绩、培养其综合能力的重要作用。展开更多
MOLECULAR PHYSIOLLGY OF HEPATOCELLULAR TRANSPORT PROTEINS Basolaferal transport systems Na+-dependent bile salt uptake Uptake of bile salts into the liver was first isolated perfused rat liver[1],isolated hepatocyte...MOLECULAR PHYSIOLLGY OF HEPATOCELLULAR TRANSPORT PROTEINS Basolaferal transport systems Na+-dependent bile salt uptake Uptake of bile salts into the liver was first isolated perfused rat liver[1],isolated hepatocyte cultures and basolateral plasma membrane vesicles [2,4].展开更多
文摘Introduction: Urinary tract infection is one of the most frequent public health problems in the world and concerns all ages. Objective: To describe the epidemiological, clinical and biological profile of urinary tract infection in the internal medicine unit of the Fousseyni Daou hospital in Kayes. Methodology: It was a descriptive and cross-sectional study with retrospective data collection which took place from January 1 to December 31, 2020 at the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes. It covered all outpatients and hospitalized patients presenting with a urinary tract infection during the study period. Results: We identified 79 cases of urinary tract infection out of 145 requests for ECBU, that is a positivity rate of 53.10% and out of a total of 1883 admissions that is a hospital prevalence of 4.19%. The age groups of 36 to 45 years and 46 to 55 years were more represented in 28 cases (35.44%) and 25 cases (31.64%) with an average age of 45 years ± 10. The female sex was predominant, 42 cases (53.16%) with a sex ratio of 0.88. Housewives were more represented 28 cases (34.44%). The majority of patients resided in rural areas 49 cases (62.03%). The history was dominated by the following pathologies: hypertension 48.10%, diabetes 36.70% and gastropathy 30.37%. The main clinical manifestations were: Urinary burning 67 cases (84.81%), Dysuria 65 cases (82.27%), Pelvic pain 59 cases (74.68%), Fever 57 cases (72.15%). The epidemiological profile of the isolated strains was dominated by enterobacteriaceae, followed by gram-positive cocci and gram-negative bacilli. The main bacteria responsible for urinary tract infections in order of frequency: Escherichia coli (45.56%), Klebsiella pneumoniae (11.39%), Pseudomonas aeruginosa (8.86%), Staphylococcus aureus (7.59%), Streptococcus sp (6.33%), Enterobacter cloacae (3.79%), Acinetobacter sp (3.79%). The study of the susceptibility and resistance profiles of the isolated strains showed significant sensitivity of enterobacteriaceae to colistin and resistance to amoxicillin and to the amoxicillin + clavulanic acid combination. Conclusion: Urinary tract infections are a major public health problem since they are responsible for significant morbidity and mortality and a high cost of care. Knowledge of the epidemiological-clinical and bacteriological profile of these infections is essential for efficient management.
文摘<strong>Introduction:</strong> Urinary tract infections (UTI) are frequent and of polymorphous clinical symptomatology in elderly subjects both in and out of hospital. In Mali, to our knowledge, no study concerning UTIs in the elderly has been conducted, hence the interest in this innovative work. <strong>Objectives:</strong> To determine the prevalence and clinical and paraclinical aspects of urinary tract infections in the elderly. <strong>Materials and Methods:</strong> This was a prospective descriptive and cross-sectional study from September 1, 2013 to August 31, 2014, <i>i.e. </i> duration of 12 months. All patients aged 65 years and over, hospitalized or ambulatory in the internal medicine department with a documented urinary tract infection were included. <strong>Results:</strong> We collected and examined 194 patients. The cytobacteriological study of urine (CBSU) was positive in 28 patients, <i>i.e. </i> a prevalence of 14.43%. The male sex represented 59.8% of the cases, the sex ratio was equal to 1.46. The age groups between 65 - 69 and 70 - 74 years were the most affected, respectively 28.57% and 39.28%. The main clinical signs were: asthenia, anorexia, dependence, fever, urinary burning, dysuria. Hospitalization was associated with urinary tract infection with P = 0.01. The group of enterobacteria were incriminated in 75% of cases. <i>Escherichia coli, Klebsiella pneumoniae</i> and <i>Pseudomonas aeruginosa</i> represented 39.28%, 14.28% and 10.71% of cases. Urinary tract infections were represented by pyelonephritis, acute prostatitis, orchi-epididymitis and simple cystitis. <strong>Conclusion:</strong> Urinary tract infection is frequent in the elderly, its clinical presentation is polymorphic and enterobacteria are the most incriminated group of bacteria.
文摘目的探讨多模态影像融合(multimodal image fusion,MMIF)辅助以案例为基础的教学法(case based learning,CBL)对心血管内科住院医师规范化培训(简称住培)效果的影响。方法选择2021年10月—2022年10月在南京医科大学第一附属医院心血管内科轮转的住院医师为研究对象,共60名。根据不同轮转时间将2021年10月—2022年3月进行轮转医师设为对照组,共27名;将2022年4月—2022年10月进行轮转的医师设为观察组,共33名。对照组予以常规教学模式,观察组行MMIF辅助CBL教学法,2组教学均持续2个月。于教学前后,评估2组的理论知识、实践能力、自主学习能力和临床思维能力;评估2组医师的教学满意度。结果观察组满意度高于对照组(96.67%vs.77.78%),差异有统计学意义(P<0.05)。带教后,2组理论知识、实践能力评分、自主学习能力和临床思维能力评分均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。结论MMIF辅助CBL教学法在心血管内科住培中的效果较好,可提高学员的理论成绩、实践能力和自主学习能力,培养其临床思维能力。
文摘探究以问题为基础的学习(problem based leaming,PBL)联合微信视频教学模式在急诊内科临床带教中的应用效果。选取2022年1月—2023年1月广东医科大学附属第二医院急诊内科的60名临床实习生作为研究对象,随机将其分为对照组(常规带教模式)和观察组(PBL联合微信视频教学模式),每组各30名。对比两组实习生的临床带教效果。结果显示,观察组各项考核成绩(理论知识、操作技能、综合病例分析)高于对照组(P<0.05);观察组各维度综合能力评分(病历书写、体格检查、临床判断、沟通技能、团队协作)高于对照组(P<0.05);观察组各项自我评价指标均优于对照组(P<0.05);观察组各维度职业认同感评分及总分高于对照组(P<0.05);观察组带教满意度高于对照组(P<0.05)。研究发现,在急诊内科临床带教中应用PBL联合微信视频教学模式,可起到提升实习生的考核成绩、培养其综合能力的重要作用。
基金supported by"H+Die Spitaler der Schweiz" the Swiss Agency for Development and Cooperation(DEZA)by the University Hospital Zurich/Switzerland
文摘MOLECULAR PHYSIOLLGY OF HEPATOCELLULAR TRANSPORT PROTEINS Basolaferal transport systems Na+-dependent bile salt uptake Uptake of bile salts into the liver was first isolated perfused rat liver[1],isolated hepatocyte cultures and basolateral plasma membrane vesicles [2,4].
