Objective To discuss the pathogenesis, etiology, clinical manifestations, diagnosis, treatment and prognosis of right sided infective endocarditis (RIE). Methods To investigate retrospectively the clinical data of pa...Objective To discuss the pathogenesis, etiology, clinical manifestations, diagnosis, treatment and prognosis of right sided infective endocarditis (RIE). Methods To investigate retrospectively the clinical data of patients with RIE admitted in our hospital from Jan 1985 to Dec 2000. Results There were 17 cases of RIE (12 male, 5 female, mean age 22 years), among which 7 with congenital heart disease, 1 with pacemaker implantation and 9 with a history of intravenous drug abuse but without underlying heart disease. Fever and multiple pulmonary emboli were the major clinical manifestations. Blood cultures were positive in 8 cases with Staphylococcus aureus as the predominant microorganism. Echocardiography detected right heart vegetations in all cases, with tricuspid valve as the structure most frequently affected. Most patients were successfully treated with antimicrobials. The outcome was favourable, with a mortality of 11.8%. Conclusions The clinical features of RIE are different from that of left sided infective endocarditis (LIE). Echocardiography plays an important role in the diagnosis of RIE.展开更多
文摘Objective To discuss the pathogenesis, etiology, clinical manifestations, diagnosis, treatment and prognosis of right sided infective endocarditis (RIE). Methods To investigate retrospectively the clinical data of patients with RIE admitted in our hospital from Jan 1985 to Dec 2000. Results There were 17 cases of RIE (12 male, 5 female, mean age 22 years), among which 7 with congenital heart disease, 1 with pacemaker implantation and 9 with a history of intravenous drug abuse but without underlying heart disease. Fever and multiple pulmonary emboli were the major clinical manifestations. Blood cultures were positive in 8 cases with Staphylococcus aureus as the predominant microorganism. Echocardiography detected right heart vegetations in all cases, with tricuspid valve as the structure most frequently affected. Most patients were successfully treated with antimicrobials. The outcome was favourable, with a mortality of 11.8%. Conclusions The clinical features of RIE are different from that of left sided infective endocarditis (LIE). Echocardiography plays an important role in the diagnosis of RIE.
