BACKGROUND We report a case of infective endocarditis(IE)in a patient with congenital heart valve lesions accompanied by IE,which was diagnosed based on blood culture analysis that revealed the presence of a gram-nega...BACKGROUND We report a case of infective endocarditis(IE)in a patient with congenital heart valve lesions accompanied by IE,which was diagnosed based on blood culture analysis that revealed the presence of a gram-negative bacterium,Streptococcus gordonii.CASE SUMMARY The patient had a history of precordial valve disease diagnosed by cardiac ultrasound,as well as a 4-mo history of fever.He was subjected to comprehensive anti-infection and anti-heart failure treatment in the internal medicine department.Further examination revealed sudden dislodgement from and perforation through the aortic valve by the superfluous organisms,as well as occurrence of bacterial emboli dislodgement,which caused bacteremia and infectious shock.He recovered and was discharged from the hospital after surgical and postoperative anti-infection treatments.CONCLUSION We review the treatment process and highlight inspirations and reflections from this case;suggest possible future changes in treatment modalities.展开更多
目的：探讨手术治疗原发性感染性心内膜炎的近远期效果。方法对2002年1月-2013年6月连续收治的符合 Duke 诊断标准的原发性感染性心内膜炎患者16例进行回顾性研究。主要终点事件为与感染性心内膜炎相关性死亡、二次手术、感染性心内膜...目的：探讨手术治疗原发性感染性心内膜炎的近远期效果。方法对2002年1月-2013年6月连续收治的符合 Duke 诊断标准的原发性感染性心内膜炎患者16例进行回顾性研究。主要终点事件为与感染性心内膜炎相关性死亡、二次手术、感染性心内膜炎复发。结果16例患者中男12例，女4例，男女比为3∶1，年龄25．0～60．6（46．7±13．9）岁，行二尖瓣置换术9例，主动脉瓣置换术4例，二尖瓣主动脉瓣联合置换术3例，30 d 内病死率为18．8％（3/16）。随访12例，随访时间0～137（42．3±5．0）月，5年生存率为80．0％，远期死亡原因主要为心功能不全、感染性心内膜炎复发。结论感染性心内膜炎仍是高病死率疾病，心脏彩色超声可以提高其诊断率，早期手术有利于提高远期效果。展开更多
文摘BACKGROUND We report a case of infective endocarditis(IE)in a patient with congenital heart valve lesions accompanied by IE,which was diagnosed based on blood culture analysis that revealed the presence of a gram-negative bacterium,Streptococcus gordonii.CASE SUMMARY The patient had a history of precordial valve disease diagnosed by cardiac ultrasound,as well as a 4-mo history of fever.He was subjected to comprehensive anti-infection and anti-heart failure treatment in the internal medicine department.Further examination revealed sudden dislodgement from and perforation through the aortic valve by the superfluous organisms,as well as occurrence of bacterial emboli dislodgement,which caused bacteremia and infectious shock.He recovered and was discharged from the hospital after surgical and postoperative anti-infection treatments.CONCLUSION We review the treatment process and highlight inspirations and reflections from this case;suggest possible future changes in treatment modalities.
文摘目的：探讨手术治疗原发性感染性心内膜炎的近远期效果。方法对2002年1月-2013年6月连续收治的符合 Duke 诊断标准的原发性感染性心内膜炎患者16例进行回顾性研究。主要终点事件为与感染性心内膜炎相关性死亡、二次手术、感染性心内膜炎复发。结果16例患者中男12例，女4例，男女比为3∶1，年龄25．0～60．6（46．7±13．9）岁，行二尖瓣置换术9例，主动脉瓣置换术4例，二尖瓣主动脉瓣联合置换术3例，30 d 内病死率为18．8％（3/16）。随访12例，随访时间0～137（42．3±5．0）月，5年生存率为80．0％，远期死亡原因主要为心功能不全、感染性心内膜炎复发。结论感染性心内膜炎仍是高病死率疾病，心脏彩色超声可以提高其诊断率，早期手术有利于提高远期效果。
