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Characteristics of Infertile Clientele Attending a Public in Vitro Fertilization Clinic: Appraising Priorities in a Low-Income Country
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作者 Gbolahan O. Obajimi Olugbenga O. Saanu +2 位作者 Ayodeji S. Adeyanju Ademola S. Olutoye Mofiyinfoluwa M. Adeyeye 《Open Journal of Epidemiology》 2024年第2期343-352,共10页
Introduction: Infertilityaffects one in six couples, and it is an important public health issue largely due to thepervasive effects on the emotional and psychological wellbeing of affected couples. In many developing ... Introduction: Infertilityaffects one in six couples, and it is an important public health issue largely due to thepervasive effects on the emotional and psychological wellbeing of affected couples. In many developing nations emphasis is placed on childbirth and inability to fulfill this role can be very distressing. There is an unmet need for assisted reproductive technology (ART) in many developing countries and where facilities exist, they are mostly privately owned, expensive and concentrated in urban areas. To bridge this gap, public fertility clinics have been established to provide subsidized care. Evaluating the characteristics and peculiarities of clientele presenting at these public facilities will aid planning and prioritization of care. Methodology: A descriptive retrospective study of 116 infertile patients presenting to the fertility clinic of the University College Hospital, Ibadan, Nigeria from inception on the 14<sup>th</sup> of February 2019 and 31<sup>st</sup> of December 2022.Data was analyzed using the Statical Package for Social Sciences (IBM, SPSS, New York) version 23. Descriptive statistics were used to summarize the results which were presented with the aid of bar charts and frequency tables. Result: The mean age of the patients was 40.70 ± 6.62 years. Post-menopausal patients accounted for about one-fifth of the study population while 80.2% (93 women) were older than 35 years. The mean duration of infertility was 9.39 ± 6.11years and nine patients (7.8%) had a duration greater than 2 decades. Secondary infertility occurred in 67.2% of the women. Twenty-nine women (25%) had undergone myomectomy prior to presentation. Hypertension (11.2%) was the most prevalent comorbidity. Nineteen patients (16.4%) had used contraceptives in the past with the male condom (36.8%)being the most preponderant. Sixty-seven patients had experienced pregnancy losses before 28 weeks of gestation while just 16 patients (13.8%) had undergone ART, and none was successful. Conclusion: Secondary infertility was the prevalent type of infertility and may not be unconnected with the low contraceptive usage and high risk of sexually transmitted infection. Late presentation coupled with a large proportion of post-menopausal clientele suggests delayed health-seeking behavior most probably due to the prohibitive cost of ART. The need to streamline services offered in public fertility clinics is paramount in low-income countries grappling with scarce resources. A pragmatic approach will involve the provision of low-cost ART, while enhancing gamete donation programs through the implementation of gamete sharing policies. This will invariably bridge the unmet need and skewed access to ART in developing countries. 展开更多
关键词 infertility Assisted Reproductive Technology low-income Priorities.
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The Evolution of Infertile Couples’ Profiles in a Congolese Population during Sixteen Years of Observation
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作者 Charlie-Junior Bikuelo Bikuelo Justin Esimo Mboloko +5 位作者 Emmanuel Ngoma Nzau Junior Mata Mboloko Mwad Mwang Yolande Kapend Guy Sibo Monzango Patrick Mogwo Sendeke Sandrine Putshu Wangange Modia 《Open Journal of Obstetrics and Gynecology》 2024年第11期1786-1794,共9页
Background: Infertility is a dramatic situation for a couple, especially in the Sub-Saharan area, known as extremely pro-natalist. Until this day infertility of tubal origin due to infection sexually transmitted, post... Background: Infertility is a dramatic situation for a couple, especially in the Sub-Saharan area, known as extremely pro-natalist. Until this day infertility of tubal origin due to infection sexually transmitted, post abortum or postpartum origin is the most frequent. Worldwide we are witnessing the transition of pathologies: from infectious to non-communicable ones. Objective: To analyze the evolution of infertile couples’ profiles over time to improve management in the future. Setting: University clinic of Kinshasa and a private clinic, the Edith Medical Center. Design: A cross-sectional analytical study. Patients: A total of 4456 patients who sought care for infertility from January 1999 to December 2014 were enrolled. Main Outcome: The evolution of socio-demographic, clinical and paraclinical parameters of infertile couples over time. Results: The average age of female patients was 33.1 ± 5.7 years and it increased by 36 days every year and the male partner by 29 days per year. The average number of cigarette rods consumed decreased by 5% per year. The average intercourse frequency per week decreased by 2% every year. A fifth of patients (21.8%) were obese. And the average BMI increased by 0.04 kg/m2 per year. Tubal occlusion was the main lesion found in hysterosalpingogram and diagnostic laparoscopy. Conclusion: Patients were more and more aged and gaining weight. A part from infection which is the main cause of infertility this day;in the future, infertility care providers will be facing non-communicable diseases, namely obesity. 展开更多
关键词 infertility infertility in Sub-Saharan Area infertility in low-income setting Etiology of infertility
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集合论、笛卡尔乘积和多项式定理在生命表研究中的应用:以取食玉米粒和茶树叶片的棉铃虫生命表为例
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作者 陈珍珍 边亚楠 +1 位作者 齐心 许永玉 《昆虫学报》 CAS CSCD 北大核心 2024年第10期1388-1403,共16页
【目的】自我重复取样技术(bootstrap technique)广泛用于计算生命表各参数的方差、标准误和置信区间(confidence interval),而配对自我重复取样检验(paired bootstrap test,PBT)则用于检测处理间的生命表参数差异。本研究以取食玉米粒... 【目的】自我重复取样技术(bootstrap technique)广泛用于计算生命表各参数的方差、标准误和置信区间(confidence interval),而配对自我重复取样检验(paired bootstrap test,PBT)则用于检测处理间的生命表参数差异。本研究以取食玉米粒和茶树叶片的棉铃虫Helicoverpa armigera生命表为例,进一步解释集合论、笛卡尔乘积和多项式定理在害虫种群生物学研究中的应用。【方法】利用年龄-龄期两性生命表对取食玉米粒和茶树叶片的棉铃虫种群参数进行分析,利用集合论、笛卡尔乘积和多项式定理将种群统计分析以明确数学的方法呈现,以检测所有可能的自我重复取样样本、精确计算种群参数置信区间以及处理之间差异的置信区间,计算可育和不育样本的概率。【结果】取食茶树叶片的棉铃虫其成虫前期存活率、内禀增长率(r)、周限增长率(λ)、净增殖率(R_(0))、平均世代周期(T)均显著低于取食玉米粒的,说明茶树叶片不是棉铃虫的适宜寄主植物。因取食茶树叶片棉铃虫种群不育样本数较多,利用bootstrap重复取样接受可育与不育样本时,其结果与不用bootstrap技术计算的差异小于5%;若取样时仅接受可育样本,结果与原数值差异显著,误差较大(>5%)。使用笛卡尔配对检验(Cartesian paired test,CPT)比较取食两种食物的棉铃虫种群的R0的差异时,可计算两种处理bootstrap抽样结果所有可能差异的精确置信区间,而使用自我重复取样检验通常会导致置信区间的估值过高或过低,尤其是自我重复取样数较小时。多项式定理可以揭示可育和不育样本的自我重复取样结果。自我重复取样抽样记录必须保留,以便在后续分析中进一步应用。【结论】本研究进一步明确了两性生命表理论的数学基础,也为昆虫学研究中的生命表技术的应用提供数学支撑。 展开更多
关键词 棉铃虫 生命表 集合论 笛卡尔乘积 多项式定理 不育自我重复取样样本
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Introducing a Trauma Registry in Mozambique: An Ethics Case Study
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作者 Fadi Hamadani Otilia Neves +6 位作者 Ana Olga Mocumbi Tarek Razek Kosar Khwaja Paola Fata Andrew Beckett Eunice Jetha Dan L. Deckelbaum 《International Journal of Clinical Medicine》 2014年第16期949-955,共7页
This paper presents a case study of implementing a trauma registry in Mozambique, a low-income country with limited current trauma surveillance. An outline of the importance of trauma registries is presented followed ... This paper presents a case study of implementing a trauma registry in Mozambique, a low-income country with limited current trauma surveillance. An outline of the importance of trauma registries is presented followed by an evidence-based approach to building a sustainable and ethical partnership with local stakeholders. 展开更多
关键词 GLOBAL Burden of Injury GLOBAL HEALTH ETHICS TRAUMA REGISTRY in low-income Countries TRAUMA System in Low-Resource settings GLOBAL HEALTH Partnership
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