Atrial fibrillation (AF), the most commonly encountered arrhythmia in clinical practice, is associated with a 2-fold increase in total cardiovascular mortality, as well as the potential for substantial morbidity, in...Atrial fibrillation (AF), the most commonly encountered arrhythmia in clinical practice, is associated with a 2-fold increase in total cardiovascular mortality, as well as the potential for substantial morbidity, including stroke, congestive heart failure, and cardiomyopathy. Its incidence and prevalence are increasing, and it represents a growing clinical and economic burden. Owing to relative inefficacy and side effects of current pharmacological and non-pharmacological therapy for AF, it remains a great challenge to improve primary and secondary AF prevention strategies to reduce this potentially enormous health burden.展开更多
文摘Atrial fibrillation (AF), the most commonly encountered arrhythmia in clinical practice, is associated with a 2-fold increase in total cardiovascular mortality, as well as the potential for substantial morbidity, including stroke, congestive heart failure, and cardiomyopathy. Its incidence and prevalence are increasing, and it represents a growing clinical and economic burden. Owing to relative inefficacy and side effects of current pharmacological and non-pharmacological therapy for AF, it remains a great challenge to improve primary and secondary AF prevention strategies to reduce this potentially enormous health burden.