In this editorial,we provide a critical review of the article by Tang et al published in the World J Clin Cases,focusing on the utilization of butorphanol for epidural analgesia during labor.Our discussion encompasses...In this editorial,we provide a critical review of the article by Tang et al published in the World J Clin Cases,focusing on the utilization of butorphanol for epidural analgesia during labor.Our discussion encompasses recent research developments in epidural labor analgesia,specifically highlighting the current status of clinical applications of butorphanol and associated treatment approaches.Epidural analgesia is widely acknowledged as the primary method for pain management during labor,offering effective and prolonged pain relief while allowing mothers to remain alert and actively participate in the delivery process.Among the various drugs utilized for epidural labor analgesia,butorphanol has received increasing attention due to its potential efficacy and distinctive pharmacological properties.As a synthetic opioid analgesic,butorphanol exhibits both agonistic and antagonistic activity on opioid receptors,striking a balance between analgesia and minimizing side effects.Nevertheless,the safety and efficacy of butorphanol in epidural labor analgesia remains controversial.While certain studies have reported positive outcomes with butorphanol,including effective pain relief and a reduced incidence of side effects,others have raised concerns about its safety and efficacy compared to traditional opioids or alternative analgesics.In addition,the optimal dosing strategy and regimen of butorphanol as an adjuvant in epidural labor analgesia still need to be verified.Through comprehensive synthesis and analysis of existing literature,we aim to evaluate the current evidence regarding the use of butorphanol for epidural labor analgesia,delineate areas of consensus and controversy,and propose future avenues for research and clinical practice in this domain.展开更多
目的:探讨改良腰麻侧卧位为主的体位管理对妊娠期糖尿病(GDM)孕妇分娩结局的影响。方法:将2021年4月—2022年1月泉州市妇幼保健院·儿童医院收治的89例GDM孕妇按照随机数表法分为两组,对照组44例予以常规干预,观察组45例予以改良腰...目的:探讨改良腰麻侧卧位为主的体位管理对妊娠期糖尿病(GDM)孕妇分娩结局的影响。方法:将2021年4月—2022年1月泉州市妇幼保健院·儿童医院收治的89例GDM孕妇按照随机数表法分为两组,对照组44例予以常规干预,观察组45例予以改良腰麻侧卧位为主的体位管理干预,观察两组分娩方式、疼痛程度、产程时间,产妇生殖道损伤及产后24 h出血量,新生儿血液指标、1 min Apgar评分、宫内窘迫发生率。结果:观察组自然分娩率高于对照组,阴道助产率、剖宫产率均低于对照组(P<0.05)。观察组潜伏期、活跃期及第二产程视觉模拟疼痛评分法(VAS)评分均低于对照组(P<0.05)。观察组第一、二产程及总产程均短于对照组(P<0.05)。观察组生殖道损伤发生率均低于对照组,产后24 h出血量少于对照组(P<0.05)。观察组新生儿p H值、血糖、碱剩余水平及1 min Apgar评分均高于对照组新生儿,观察组宫内窘迫发生率低于对照组(P<0.05)。结论:改良腰麻侧卧位为主的体位管理应用于GDM孕妇可减轻疼痛程度,促进产程进展,改善母婴结局。展开更多
文摘In this editorial,we provide a critical review of the article by Tang et al published in the World J Clin Cases,focusing on the utilization of butorphanol for epidural analgesia during labor.Our discussion encompasses recent research developments in epidural labor analgesia,specifically highlighting the current status of clinical applications of butorphanol and associated treatment approaches.Epidural analgesia is widely acknowledged as the primary method for pain management during labor,offering effective and prolonged pain relief while allowing mothers to remain alert and actively participate in the delivery process.Among the various drugs utilized for epidural labor analgesia,butorphanol has received increasing attention due to its potential efficacy and distinctive pharmacological properties.As a synthetic opioid analgesic,butorphanol exhibits both agonistic and antagonistic activity on opioid receptors,striking a balance between analgesia and minimizing side effects.Nevertheless,the safety and efficacy of butorphanol in epidural labor analgesia remains controversial.While certain studies have reported positive outcomes with butorphanol,including effective pain relief and a reduced incidence of side effects,others have raised concerns about its safety and efficacy compared to traditional opioids or alternative analgesics.In addition,the optimal dosing strategy and regimen of butorphanol as an adjuvant in epidural labor analgesia still need to be verified.Through comprehensive synthesis and analysis of existing literature,we aim to evaluate the current evidence regarding the use of butorphanol for epidural labor analgesia,delineate areas of consensus and controversy,and propose future avenues for research and clinical practice in this domain.
文摘目的:探讨改良腰麻侧卧位为主的体位管理对妊娠期糖尿病(GDM)孕妇分娩结局的影响。方法:将2021年4月—2022年1月泉州市妇幼保健院·儿童医院收治的89例GDM孕妇按照随机数表法分为两组,对照组44例予以常规干预,观察组45例予以改良腰麻侧卧位为主的体位管理干预,观察两组分娩方式、疼痛程度、产程时间,产妇生殖道损伤及产后24 h出血量,新生儿血液指标、1 min Apgar评分、宫内窘迫发生率。结果:观察组自然分娩率高于对照组,阴道助产率、剖宫产率均低于对照组(P<0.05)。观察组潜伏期、活跃期及第二产程视觉模拟疼痛评分法(VAS)评分均低于对照组(P<0.05)。观察组第一、二产程及总产程均短于对照组(P<0.05)。观察组生殖道损伤发生率均低于对照组,产后24 h出血量少于对照组(P<0.05)。观察组新生儿p H值、血糖、碱剩余水平及1 min Apgar评分均高于对照组新生儿,观察组宫内窘迫发生率低于对照组(P<0.05)。结论:改良腰麻侧卧位为主的体位管理应用于GDM孕妇可减轻疼痛程度,促进产程进展,改善母婴结局。
