AIM：To provide a side-by-side analysis of the summary of safety and effectiveness data（SSED）submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.METHODS：SSED reports subm...AIM：To provide a side-by-side analysis of the summary of safety and effectiveness data（SSED）submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.METHODS：SSED reports submitted to the FDA for KAMRA and Raindrop were compared with respect to loss of corrected distance visual acuity（CDVA）,adverse event rates,induction of astigmatism,retention of contrast sensitivity,stability of manifest refractive spherical equivalent（MRSE）,and achieved monocular uncorrected near visual acuity（UNVA）at 24mo.RESULTS：Totally 442/508 of KAMRA patients and344/373 Raindrop patients remained enrolled in the clinical trials at 24mo.The proportion of KAMRA and Raindrop patients who lost≥2 lines of CDVA at 24mo was 3.4%and1%,respectively.The adverse event rate was comparable between the devices.No significant inductions of astigmatism were noted.Both technologies induced a transient myopic shift in MRSE followed by a hyperopic shift and subsequent stabilization.Totally 87%of KAMRA and 98%of Raindrop patients attained a monocular UNVA of J5（20/40）or better at 24mo,28%of KAMRA and 67%of Raindrop patients attained a monocular UNVA of J1（20/20）or better at 24mo.CONCLUSION：Both devices can be considered safe and effective,however,the results of corneal inlay implantation are mixed,and long-term patient satisfaction will likely depend on subjective expectations about the capabilities of the inlays.Variability in surgical technique and postoperative care within and between the two clinical trials diminishes the comparative power of this article.展开更多
The purpose of this study was to demonstrate the improvement of hip joint dysregulation, including pain (coxalgia), tension, and restriction of joint mobility, using a dental gold alloy inlay. The subject was a 63-yea...The purpose of this study was to demonstrate the improvement of hip joint dysregulation, including pain (coxalgia), tension, and restriction of joint mobility, using a dental gold alloy inlay. The subject was a 63-year-old man who was suffering from the abovementioned symptoms for several months. On placement of the gold alloy inlay on his chest, the joint flexibility was observed to increase, and the severity of the abovementioned symptoms decreased. When the inlay was placed in his tooth, the flexibility of the joint further increased, and all other symptoms disappeared. No side effects were observed, and the prognosis was good. We believe that these effects may be explained using the electromagnetic waves emitted by the inlay and by the restoration of biting conditions. Future multidisciplinary research focusing on possible underlying mechanisms regarding the relation between electromagnetic waves and dentistry is necessary.展开更多
In the experimental garden of the Department of Soil Bioengineering and Landscape Construction, University of Applied Life Sciences in Vienna, Austria, coarse root systems of three different brush species were complet...In the experimental garden of the Department of Soil Bioengineering and Landscape Construction, University of Applied Life Sciences in Vienna, Austria, coarse root systems of three different brush species were completely excavated and semiutomatically digitized. The species were Lonicera xylosteum, Ligustrum vulgare and Euonymus europaeus. The 3-D root architectures reveal different growth strategies between species, which are related to ecological characteristics and physical soil properties. The root architecture of Lonicera xylosteum and Ligustrum vulgare, planted in the under layer of the live slope grading, where the soil is very tight and the soil water content and fertility are relatively low, is shallow. However, the root distribution of E. europaeus, planted in the middle layer, where environmental conditions are better, is deeper. Most of the root biomass of the three species is concentrated in the 0-30 cm soil layer. A quarter of the root biomass ofLigustrum vulgare is distributed in the upper layer of the plant inlay. E. europaeus has a relatively even distribution in the 30-0 cm and 60-90 cm soil layer.展开更多
Objectives: A comparison study between ceramic full coverage FPDs & 3 designs of ceramic inlay retained FPDs regarding vertical marginal gap & retention. Materials & Methods: Twenty samples were construc- ...Objectives: A comparison study between ceramic full coverage FPDs & 3 designs of ceramic inlay retained FPDs regarding vertical marginal gap & retention. Materials & Methods: Twenty samples were construc- ted and divided into 4 groups according to the type of restorations: full coverage, inlay-shaped (occluso-pro- ximal inlay + proximal box), tub-shaped (occluso-pro- ximal inlay), and proximal box-shaped FPDs. All samples were subjected to a vertical marginal gap measurements followed by a retention test. Results: The vertical marginal gap data showed no significant difference between full coverage FPDs, the tub-shap- ed inlay retained FPDs and the proximal box-shaped inlay retained FPDs. While there was a difference between these three designs and the inlay retained FPDs. Regarding retention, the full coverage FPDs recorded higher retentive strengths and was signifi-cant difference than all inlay retained FPDs designs tested. The inlay-shaped design was significant dif-ference than the other two inlay retained FPDs de-signs. Conclusions: There was no significant differ- ence between full coverage FPDs, tub-shaped & pro- ximal box shaped inlay retained FPDs as regard ver- tical marginal discrepancies. While, the inlay-haped design showed the highest vertical marginal discrep- ancies. The premolar & molar retainers for the same type of restorations showed no difference in vertical marginal discrepancies. All measured vertical mar- ginal discrepancies were in the range of clinical ac- ceptance. The full coverage FPDs recorded higher retentive strengths than all inlay retained FPDs de- signs tested. The inlay-shaped design recorded the highest retentive strengths among the three inlay re- tained FPDs designs. There was no difference as re- gard retentive strengths between tub-shaped & pro- ximal box shaped inlay retained FPDs.展开更多
IN Chinese costume dramas, imperial concubines are always seen wearing delicate decorations on the head, from phoenix coronets dotted with splendid jewelry to hairpins with elegant dangling ornaments. Those crafted it...IN Chinese costume dramas, imperial concubines are always seen wearing delicate decorations on the head, from phoenix coronets dotted with splendid jewelry to hairpins with elegant dangling ornaments. Those crafted items combine colorful jewelry with gold wires;the craft used to manufacture them is called Chinese filigree inlay.展开更多
The entire roller inlayed block intelligence cold strip shape meter is developed successfully in this paper,which can stably work chronically in the cold rolling workshop,the independent innovation of the key technolo...The entire roller inlayed block intelligence cold strip shape meter is developed successfully in this paper,which can stably work chronically in the cold rolling workshop,the independent innovation of the key technology of cold strip shape measuring,the foreign technical monopoly and blockade are broken through.The structural form which is different from the international popular segmented detection roller is put forward,the entire detection roller inlayed block is developed,a group of elastic blocks in that the sense organs are installed are inlayed in the radial symmetry rectangular grooves of the detection roller body,the entire roller structure is composed of elastic pieces and the roller body,the scratch of the strip surface due to different thermal expansion of the traditional detection roller measuring unit is avoided effectively.The signal transmission form which is different form the international popular dry slip ring is put forward,the spray wet slip ring is developed,slip ring and detection roller can be taken down and installed as possibly as fast,so the maintain is convenient,while through the section auto-spray cleaning,lubrication and cooling, the service life is remarkable improved and the outside interference signal is reduced.The signal processing form which is different form the international popular gathering card is put forward,the embedded DSP shape signal processing hardware system is developed,the electromagnet,temperature,humidity and vibration's interference of industry practice to shape transmission signal can be effectively avoided,which can guarantee the instantaneity and measured precision of shape measured signal.The shape signal processing software system whose function contains error compensation,pattern recognition,establishment of the target shape and the closed-loop control calculation is built,the shape meter' computer human interaction is friendly,and function of shape meter is strong,at the same time the intellectualized level of the shape meter is improved.Now,this shape meter has been successfully applied on the 1 250 mm cold strip mill of Angang Steel Company Limited,the long-term operating testing is done,every guide line achieves the anticipative effect,the measuring precision is high and the measuring signal is stable and reliable,the shape meter is tested on high speed,big tension,changed wrap angle and big depressed complicated working conditions,any scratch of the detection roller surface and the strip surface is not appearing,it can completely adapt well to the industrial production environment,reaching the international advanced level.展开更多
Background:Schistosomiasis is a chronic parasitic disease caused by blood flukes(trematode worms)of the genus Schistosoma.Its transmission has been reported in 78 countries affecting at least 258 million people world-...Background:Schistosomiasis is a chronic parasitic disease caused by blood flukes(trematode worms)of the genus Schistosoma.Its transmission has been reported in 78 countries affecting at least 258 million people world-wide.It was documented that S.japonicum species was prevalent in Shan State,Myanmar,but the serological study was not conducted yet.General objective of the present study was to detect schistosoma antibodies and explore associated factors among local residents living around Inlay Lake,Nyaung Shwe Township,and Southern Shan State,Myanmar.Methods:An exploratory and cross-sectional analytic study was conducted among local residents(n=315)in selected rural health center(RHC)areas from December 2012 through June 2013.The participants were interviewed with pretested semi-structured questionnaires and their blood samples(serum)were tested using Schistosomiasis Serology Microwell ELISA test kits(sensitivity 100%and specificity 85%)which detected IgG antibodies but could not distinguish between a new and past infection.Data collected were analysed by SPSS software 16.0 and associations of variables were determined by Chi-squared test with a significant level set at 0.05.Results:Schistosoma seroprevalence(IgG)in study area was found to be 23.8%(95%CI:18.8-28.8%).The present study is the first and foremost study producing serological evidence of schistosoma infection-one of the neglected tropical diseases-in local people of Myanmar.The factors significantly associated with seropositivity were being male[OR=2.6(95%CI:1.5-4.49),P<0.001],residence[OR=3.41(95%CI:1.6-7.3),P<0.05 for Khaung Daing vs.Min Chaung]and education levels[OR=4.5(95%CI:1.18-17.16),P<0.05 for illiterate/3Rs level vs.high/graduate and OR=3.16(95%CI:1.26-7.93),P<0.05 for primary/middle level vs.high/graduate]all factors classically associated with risk of schistosoma infection.None of the behavioural factors tested were significantly associated with seropositivity.Conclusion:Schistosoma infection serologically detected was most probably present at some time in this location of Myanmar,and this should be further confirmed parasitologically and kept under surveillance.Proper trainings on diagnosis,treatment,prevention and control of schistosomiasis should be provided to the healthcare providers.展开更多
Filigree inlay is a special traditional craft technique in the manufacture of Beijing jewelry. It uses gold, platinum, silver and copper as its raw materials. The artisans use very complicated processes to make differ...Filigree inlay is a special traditional craft technique in the manufacture of Beijing jewelry. It uses gold, platinum, silver and copper as its raw materials. The artisans use very complicated processes to make different designs and patterns. Then they inlay diamonds and gems of all kinds to make delicate jewelry and ornamental objects. They are a feast for the eyes.展开更多
文摘AIM：To provide a side-by-side analysis of the summary of safety and effectiveness data（SSED）submitted to the FDA for the KAMRA and Raindrop corneal inlays for the correction of presbyopia.METHODS：SSED reports submitted to the FDA for KAMRA and Raindrop were compared with respect to loss of corrected distance visual acuity（CDVA）,adverse event rates,induction of astigmatism,retention of contrast sensitivity,stability of manifest refractive spherical equivalent（MRSE）,and achieved monocular uncorrected near visual acuity（UNVA）at 24mo.RESULTS：Totally 442/508 of KAMRA patients and344/373 Raindrop patients remained enrolled in the clinical trials at 24mo.The proportion of KAMRA and Raindrop patients who lost≥2 lines of CDVA at 24mo was 3.4%and1%,respectively.The adverse event rate was comparable between the devices.No significant inductions of astigmatism were noted.Both technologies induced a transient myopic shift in MRSE followed by a hyperopic shift and subsequent stabilization.Totally 87%of KAMRA and 98%of Raindrop patients attained a monocular UNVA of J5（20/40）or better at 24mo,28%of KAMRA and 67%of Raindrop patients attained a monocular UNVA of J1（20/20）or better at 24mo.CONCLUSION：Both devices can be considered safe and effective,however,the results of corneal inlay implantation are mixed,and long-term patient satisfaction will likely depend on subjective expectations about the capabilities of the inlays.Variability in surgical technique and postoperative care within and between the two clinical trials diminishes the comparative power of this article.
文摘The purpose of this study was to demonstrate the improvement of hip joint dysregulation, including pain (coxalgia), tension, and restriction of joint mobility, using a dental gold alloy inlay. The subject was a 63-year-old man who was suffering from the abovementioned symptoms for several months. On placement of the gold alloy inlay on his chest, the joint flexibility was observed to increase, and the severity of the abovementioned symptoms decreased. When the inlay was placed in his tooth, the flexibility of the joint further increased, and all other symptoms disappeared. No side effects were observed, and the prognosis was good. We believe that these effects may be explained using the electromagnetic waves emitted by the inlay and by the restoration of biting conditions. Future multidisciplinary research focusing on possible underlying mechanisms regarding the relation between electromagnetic waves and dentistry is necessary.
文摘In the experimental garden of the Department of Soil Bioengineering and Landscape Construction, University of Applied Life Sciences in Vienna, Austria, coarse root systems of three different brush species were completely excavated and semiutomatically digitized. The species were Lonicera xylosteum, Ligustrum vulgare and Euonymus europaeus. The 3-D root architectures reveal different growth strategies between species, which are related to ecological characteristics and physical soil properties. The root architecture of Lonicera xylosteum and Ligustrum vulgare, planted in the under layer of the live slope grading, where the soil is very tight and the soil water content and fertility are relatively low, is shallow. However, the root distribution of E. europaeus, planted in the middle layer, where environmental conditions are better, is deeper. Most of the root biomass of the three species is concentrated in the 0-30 cm soil layer. A quarter of the root biomass ofLigustrum vulgare is distributed in the upper layer of the plant inlay. E. europaeus has a relatively even distribution in the 30-0 cm and 60-90 cm soil layer.
文摘Objectives: A comparison study between ceramic full coverage FPDs & 3 designs of ceramic inlay retained FPDs regarding vertical marginal gap & retention. Materials & Methods: Twenty samples were construc- ted and divided into 4 groups according to the type of restorations: full coverage, inlay-shaped (occluso-pro- ximal inlay + proximal box), tub-shaped (occluso-pro- ximal inlay), and proximal box-shaped FPDs. All samples were subjected to a vertical marginal gap measurements followed by a retention test. Results: The vertical marginal gap data showed no significant difference between full coverage FPDs, the tub-shap- ed inlay retained FPDs and the proximal box-shaped inlay retained FPDs. While there was a difference between these three designs and the inlay retained FPDs. Regarding retention, the full coverage FPDs recorded higher retentive strengths and was signifi-cant difference than all inlay retained FPDs designs tested. The inlay-shaped design was significant dif-ference than the other two inlay retained FPDs de-signs. Conclusions: There was no significant differ- ence between full coverage FPDs, tub-shaped & pro- ximal box shaped inlay retained FPDs as regard ver- tical marginal discrepancies. While, the inlay-haped design showed the highest vertical marginal discrep- ancies. The premolar & molar retainers for the same type of restorations showed no difference in vertical marginal discrepancies. All measured vertical mar- ginal discrepancies were in the range of clinical ac- ceptance. The full coverage FPDs recorded higher retentive strengths than all inlay retained FPDs de- signs tested. The inlay-shaped design recorded the highest retentive strengths among the three inlay re- tained FPDs designs. There was no difference as re- gard retentive strengths between tub-shaped & pro- ximal box shaped inlay retained FPDs.
文摘IN Chinese costume dramas, imperial concubines are always seen wearing delicate decorations on the head, from phoenix coronets dotted with splendid jewelry to hairpins with elegant dangling ornaments. Those crafted items combine colorful jewelry with gold wires;the craft used to manufacture them is called Chinese filigree inlay.
文摘The entire roller inlayed block intelligence cold strip shape meter is developed successfully in this paper,which can stably work chronically in the cold rolling workshop,the independent innovation of the key technology of cold strip shape measuring,the foreign technical monopoly and blockade are broken through.The structural form which is different from the international popular segmented detection roller is put forward,the entire detection roller inlayed block is developed,a group of elastic blocks in that the sense organs are installed are inlayed in the radial symmetry rectangular grooves of the detection roller body,the entire roller structure is composed of elastic pieces and the roller body,the scratch of the strip surface due to different thermal expansion of the traditional detection roller measuring unit is avoided effectively.The signal transmission form which is different form the international popular dry slip ring is put forward,the spray wet slip ring is developed,slip ring and detection roller can be taken down and installed as possibly as fast,so the maintain is convenient,while through the section auto-spray cleaning,lubrication and cooling, the service life is remarkable improved and the outside interference signal is reduced.The signal processing form which is different form the international popular gathering card is put forward,the embedded DSP shape signal processing hardware system is developed,the electromagnet,temperature,humidity and vibration's interference of industry practice to shape transmission signal can be effectively avoided,which can guarantee the instantaneity and measured precision of shape measured signal.The shape signal processing software system whose function contains error compensation,pattern recognition,establishment of the target shape and the closed-loop control calculation is built,the shape meter' computer human interaction is friendly,and function of shape meter is strong,at the same time the intellectualized level of the shape meter is improved.Now,this shape meter has been successfully applied on the 1 250 mm cold strip mill of Angang Steel Company Limited,the long-term operating testing is done,every guide line achieves the anticipative effect,the measuring precision is high and the measuring signal is stable and reliable,the shape meter is tested on high speed,big tension,changed wrap angle and big depressed complicated working conditions,any scratch of the detection roller surface and the strip surface is not appearing,it can completely adapt well to the industrial production environment,reaching the international advanced level.
基金The research project was funded by World Health Organization.Project name:SYSSER 2012-2013Project number:SEMMR 1207308+1 种基金OSER number:10.009.SEO1.MMRO3Top task number:24.3.
文摘Background:Schistosomiasis is a chronic parasitic disease caused by blood flukes(trematode worms)of the genus Schistosoma.Its transmission has been reported in 78 countries affecting at least 258 million people world-wide.It was documented that S.japonicum species was prevalent in Shan State,Myanmar,but the serological study was not conducted yet.General objective of the present study was to detect schistosoma antibodies and explore associated factors among local residents living around Inlay Lake,Nyaung Shwe Township,and Southern Shan State,Myanmar.Methods:An exploratory and cross-sectional analytic study was conducted among local residents(n=315)in selected rural health center(RHC)areas from December 2012 through June 2013.The participants were interviewed with pretested semi-structured questionnaires and their blood samples(serum)were tested using Schistosomiasis Serology Microwell ELISA test kits(sensitivity 100%and specificity 85%)which detected IgG antibodies but could not distinguish between a new and past infection.Data collected were analysed by SPSS software 16.0 and associations of variables were determined by Chi-squared test with a significant level set at 0.05.Results:Schistosoma seroprevalence(IgG)in study area was found to be 23.8%(95%CI:18.8-28.8%).The present study is the first and foremost study producing serological evidence of schistosoma infection-one of the neglected tropical diseases-in local people of Myanmar.The factors significantly associated with seropositivity were being male[OR=2.6(95%CI:1.5-4.49),P<0.001],residence[OR=3.41(95%CI:1.6-7.3),P<0.05 for Khaung Daing vs.Min Chaung]and education levels[OR=4.5(95%CI:1.18-17.16),P<0.05 for illiterate/3Rs level vs.high/graduate and OR=3.16(95%CI:1.26-7.93),P<0.05 for primary/middle level vs.high/graduate]all factors classically associated with risk of schistosoma infection.None of the behavioural factors tested were significantly associated with seropositivity.Conclusion:Schistosoma infection serologically detected was most probably present at some time in this location of Myanmar,and this should be further confirmed parasitologically and kept under surveillance.Proper trainings on diagnosis,treatment,prevention and control of schistosomiasis should be provided to the healthcare providers.
文摘Filigree inlay is a special traditional craft technique in the manufacture of Beijing jewelry. It uses gold, platinum, silver and copper as its raw materials. The artisans use very complicated processes to make different designs and patterns. Then they inlay diamonds and gems of all kinds to make delicate jewelry and ornamental objects. They are a feast for the eyes.
