The European Union （EU） this year has entered into the next phase of its existence, not only in terms of new economic conditions of the unwinding of the financial and economic crisis, but also on the basis of the re...The European Union （EU） this year has entered into the next phase of its existence, not only in terms of new economic conditions of the unwinding of the financial and economic crisis, but also on the basis of the results of European Parliament elections and the adoption of the EU financial fi＇amework for the period from 2014 to 2020. These indisputable facts does not change our view of the situation in which the EU is, or at major tasks whose managing can be considered as condition of its continued existence as an important part of the global economy. As the fundamental problem of the EU, persisting differences in economic level of the member states is considered. The aim of this paper is not to formulate and even to propose how the EU should look like in the future, but to assess criteria of decision making about concept of its future direction. In this context, the verification of argument will be performed, that only the integration of the countries that have common interests and objectives respectively are able to make the same efforts to meet them, is in certain stages of integration possible and functional. Conversely, a broader territorial structured integration of countries with significantly different economic parameters is feasible and functional only at lower stages of integration. This paper starts from that the process of economic convergence among member states as a condition for integration can be realized at the lower stage of the integration process, in terms of economic and monetary union, then only the expense of reducing the dynamics of economic development of integration group as a whole. Some degree of equilibrium of economic levels represents an important condition for the success of the integration project. To meet this goal, current differences in economic level of individual EU member states （comparative analysis using indicators of growth rate and development of GDP/capita） will be analyzed, including the assessment of the cost of the EU for the implementation of cohesion policy, both in terms of the economic crisis and the phase of requirement to the revival of the European economy. In this context, also the effectiveness of institutional arrangements of decision-making procedures will be assessed.展开更多
AIM: To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our pre...AIM: To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our preliminary study. METHODS: We examined relationships between MVC and clinicopathological factors in 128 HCC patients. The modifi ed Japan Integrated Staging score (mJIS) was applied to examine subsets of HCC patients. RESULTS: Median MVC was 178/mm^2, which was used as a cut-off value. MVC was not signif icantly associated with any clinicopathologic factors or postoperative recurrent rate. Lower MVC was associated with poor disease-free and overall survivals by univariate analysis (P = 0.039 and P = 0.087, respectively) and lower MVC represented an independent poor prognostic factor in disease-free survival by Cox’s multivariateanalysis (risk ratio, 1.64; P = 0.024), in addition to tumor size, vascular invasion, macroscopic fi nding and hepatic dysfunction. Signifi cant differences in disease-free and overall survivals by MVC were observed in HCC patients with mJIS 2 (P = 0.046 and P = 0.0014, respectively), but not in those with other scores. CONCLUSION: Tumor MVC appears to offer a useful prognostic marker of HCC patient survival, particularly in HCC patients with mJIS 2.展开更多
AIM： To compare the prognosis of patients who underwent hepatectomy and ablation using the modified Japan Integrated Staging score （mJIS）. METHODS： We examined the clinicopathologic records and patient outcomes in...AIM： To compare the prognosis of patients who underwent hepatectomy and ablation using the modified Japan Integrated Staging score （mJIS）. METHODS： We examined the clinicopathologic records and patient outcomes in 278 HCC patients including 226 undergoing hepatectomy and 52 undergoing ablation therapy. RESULTS： Cirrhosis was more frequent in the ablation group. Tumor size, number and presence of vascular invasion were significantly higher in the operation group compared to the ablation group. The local recurrence rate adjacent to treated lesions was significantly higher in the ablation group compared to the operation group （P 〈 0.05）. The 3- and 5-year survival rates in the ablation and the operation group were 66% and 78%, and 50% and 63%, respectively, but not significantly different. Over 50% survival rates were observed in patients with a m.lIS score of 0-2 in both groups. However, survival rates with a score of 3-5 in both groups were significantly lower. CONCLUSION： According to the mJIS system, both local treatments could be selected for patients with a score of 0-2. However, for patients with a score more than 3, liver transplantation might be a better option in patients with HCC.展开更多
In the 20th century, manufacturing industries created a great amount of wealth for mankind, but they also caused the serious environmental pollution. Therefore, the implementation of green manufacturing will be impera...In the 20th century, manufacturing industries created a great amount of wealth for mankind, but they also caused the serious environmental pollution. Therefore, the implementation of green manufacturing will be imperative for manufacturing industries in the 21st century. The philosophy of sustainable development is necessarily and importantly used in the enterprise survival and progress. So, the green manufacturing prevails in the whole world, which appeals to the research from lots of experts and governments. However, how we can assess the green degree of the product becomes a significant problem to us. From the sustainable development view, it is pointed out in this paper how an enterprise can properly assess the green degree of the green products, which uses different indexes to measure the different influence.展开更多
文摘The European Union （EU） this year has entered into the next phase of its existence, not only in terms of new economic conditions of the unwinding of the financial and economic crisis, but also on the basis of the results of European Parliament elections and the adoption of the EU financial fi＇amework for the period from 2014 to 2020. These indisputable facts does not change our view of the situation in which the EU is, or at major tasks whose managing can be considered as condition of its continued existence as an important part of the global economy. As the fundamental problem of the EU, persisting differences in economic level of the member states is considered. The aim of this paper is not to formulate and even to propose how the EU should look like in the future, but to assess criteria of decision making about concept of its future direction. In this context, the verification of argument will be performed, that only the integration of the countries that have common interests and objectives respectively are able to make the same efforts to meet them, is in certain stages of integration possible and functional. Conversely, a broader territorial structured integration of countries with significantly different economic parameters is feasible and functional only at lower stages of integration. This paper starts from that the process of economic convergence among member states as a condition for integration can be realized at the lower stage of the integration process, in terms of economic and monetary union, then only the expense of reducing the dynamics of economic development of integration group as a whole. Some degree of equilibrium of economic levels represents an important condition for the success of the integration project. To meet this goal, current differences in economic level of individual EU member states （comparative analysis using indicators of growth rate and development of GDP/capita） will be analyzed, including the assessment of the cost of the EU for the implementation of cohesion policy, both in terms of the economic crisis and the phase of requirement to the revival of the European economy. In this context, also the effectiveness of institutional arrangements of decision-making procedures will be assessed.
文摘AIM: To elucidate the relationship between the microvessel count (MVC) by CD34 analyzed by immunohistochemical method and prognosis in hepatocellular carcinoma (HCC) patients who underwent hepatectomy based on our preliminary study. METHODS: We examined relationships between MVC and clinicopathological factors in 128 HCC patients. The modifi ed Japan Integrated Staging score (mJIS) was applied to examine subsets of HCC patients. RESULTS: Median MVC was 178/mm^2, which was used as a cut-off value. MVC was not signif icantly associated with any clinicopathologic factors or postoperative recurrent rate. Lower MVC was associated with poor disease-free and overall survivals by univariate analysis (P = 0.039 and P = 0.087, respectively) and lower MVC represented an independent poor prognostic factor in disease-free survival by Cox’s multivariateanalysis (risk ratio, 1.64; P = 0.024), in addition to tumor size, vascular invasion, macroscopic fi nding and hepatic dysfunction. Signifi cant differences in disease-free and overall survivals by MVC were observed in HCC patients with mJIS 2 (P = 0.046 and P = 0.0014, respectively), but not in those with other scores. CONCLUSION: Tumor MVC appears to offer a useful prognostic marker of HCC patient survival, particularly in HCC patients with mJIS 2.
文摘AIM： To compare the prognosis of patients who underwent hepatectomy and ablation using the modified Japan Integrated Staging score （mJIS）. METHODS： We examined the clinicopathologic records and patient outcomes in 278 HCC patients including 226 undergoing hepatectomy and 52 undergoing ablation therapy. RESULTS： Cirrhosis was more frequent in the ablation group. Tumor size, number and presence of vascular invasion were significantly higher in the operation group compared to the ablation group. The local recurrence rate adjacent to treated lesions was significantly higher in the ablation group compared to the operation group （P 〈 0.05）. The 3- and 5-year survival rates in the ablation and the operation group were 66% and 78%, and 50% and 63%, respectively, but not significantly different. Over 50% survival rates were observed in patients with a m.lIS score of 0-2 in both groups. However, survival rates with a score of 3-5 in both groups were significantly lower. CONCLUSION： According to the mJIS system, both local treatments could be selected for patients with a score of 0-2. However, for patients with a score more than 3, liver transplantation might be a better option in patients with HCC.
基金This paper is supported by National Natural Science Foundation of China （No.70472034）.
文摘In the 20th century, manufacturing industries created a great amount of wealth for mankind, but they also caused the serious environmental pollution. Therefore, the implementation of green manufacturing will be imperative for manufacturing industries in the 21st century. The philosophy of sustainable development is necessarily and importantly used in the enterprise survival and progress. So, the green manufacturing prevails in the whole world, which appeals to the research from lots of experts and governments. However, how we can assess the green degree of the product becomes a significant problem to us. From the sustainable development view, it is pointed out in this paper how an enterprise can properly assess the green degree of the green products, which uses different indexes to measure the different influence.
