Hepatocellular carcinoma(HCC)constitutes the fifth most frequent malignancy worldwide and the third most frequent cause of cancer-related deaths.Currently,treatment selection is based on the stage of the disease.Emerg...Hepatocellular carcinoma(HCC)constitutes the fifth most frequent malignancy worldwide and the third most frequent cause of cancer-related deaths.Currently,treatment selection is based on the stage of the disease.Emerging fields such as three-dimensional(3D)printing,3D bioprinting,artificial intelligence(AI),and machine learning(ML)could lead to evidence-based,individualized management of HCC.In this review,we comprehensively report the current applications of 3D printing,3D bioprinting,and AI/ML-based models in HCC management;we outline the significant challenges to the broad use of these novel technologies in the clinical setting with the goal of identifying means to overcome them,and finally,we discuss the opportunities that arise from these applications.Notably,regarding 3D printing and bioprinting-related challenges,we elaborate on cost and cost-effectiveness,cell sourcing,cell viability,safety,accessibility,regulation,and legal and ethical concerns.Similarly,regarding AI/ML-related challenges,we elaborate on intellectual property,liability,intrinsic biases,data protection,cybersecurity,ethical challenges,and transparency.Our findings show that AI and 3D printing applications in HCC management and healthcare,in general,are steadily expanding;thus,these technologies will be integrated into the clinical setting sooner or later.Therefore,we believe that physicians need to become familiar with these technologies and prepare to engage with them constructively.展开更多
The evolution of the society and economy has stimulated the development of Knowledge Service(KS), making it an indispensable solution to address future challenges facing libraries and information institutions. However...The evolution of the society and economy has stimulated the development of Knowledge Service(KS), making it an indispensable solution to address future challenges facing libraries and information institutions. However at present, academic research on knowledge service is falling short and its definition is far from clear and complete. As such,this article proposes the Three-dimensional Framework Knowledge Service(TdFKS) for libraries and information institutions based on the knowledge value chain model. By making reliability analysis and mean value analysis of a questionnaire survey result, the article clarifies the structure of the three-dimensional framework and verifies the rationality of the TdFKS.展开更多
Artificial intelligence(AI)is the study of algorithms that enable machines to analyze and execute cognitive activities including problem solving,object and word recognition,reduce the inevitable errors to improve the ...Artificial intelligence(AI)is the study of algorithms that enable machines to analyze and execute cognitive activities including problem solving,object and word recognition,reduce the inevitable errors to improve the diagnostic accuracy,and decision-making.Hepatobiliary procedures are technically complex and the use of AI in perioperative management can improve patient outcomes as discussed below.Three-dimensional(3D)reconstruction of images obtained via ultrasound,computed tomography scan or magnetic resonance imaging,can help surgeons better visualize the surgical sites with added depth perception.Preoperative 3D planning is associated with lesser operative time and intraoperative complications.Also,a more accurate assessment is noted,which leads to fewer operative complications.Images can be converted into physical models with 3D printing technology,which can be of educational value to students and trainees.3D images can be combined to provide 3D visualization,which is used for preoperative navigation,allowing for more precise localization of tumors and vessels.Nevertheless,AI enables surgeons to provide better,personalized care for each patient.展开更多
Prosthodontics,deals in the restoration and replacement of missing and structurally compromised teeth,this field has been remarkably transformed in the last two decades.Through the integration of digital imaging and t...Prosthodontics,deals in the restoration and replacement of missing and structurally compromised teeth,this field has been remarkably transformed in the last two decades.Through the integration of digital imaging and threedimensional printing,prosthodontics has evolved to provide more durable,precise,and patient-centric outcome.However,as we stand at the convergence of technology and healthcare,a new era is emerging,one that holds immense promise for the field and that is artificial intelligence(AI).In this paper,we explored the fascinating challenges and prospects associated with the future of prosthodontics in the era of AI.展开更多
文摘Hepatocellular carcinoma(HCC)constitutes the fifth most frequent malignancy worldwide and the third most frequent cause of cancer-related deaths.Currently,treatment selection is based on the stage of the disease.Emerging fields such as three-dimensional(3D)printing,3D bioprinting,artificial intelligence(AI),and machine learning(ML)could lead to evidence-based,individualized management of HCC.In this review,we comprehensively report the current applications of 3D printing,3D bioprinting,and AI/ML-based models in HCC management;we outline the significant challenges to the broad use of these novel technologies in the clinical setting with the goal of identifying means to overcome them,and finally,we discuss the opportunities that arise from these applications.Notably,regarding 3D printing and bioprinting-related challenges,we elaborate on cost and cost-effectiveness,cell sourcing,cell viability,safety,accessibility,regulation,and legal and ethical concerns.Similarly,regarding AI/ML-related challenges,we elaborate on intellectual property,liability,intrinsic biases,data protection,cybersecurity,ethical challenges,and transparency.Our findings show that AI and 3D printing applications in HCC management and healthcare,in general,are steadily expanding;thus,these technologies will be integrated into the clinical setting sooner or later.Therefore,we believe that physicians need to become familiar with these technologies and prepare to engage with them constructively.
基金supported by the National Planning Office of Philosophy and Social Science(Grant No.06BTQ027)
文摘The evolution of the society and economy has stimulated the development of Knowledge Service(KS), making it an indispensable solution to address future challenges facing libraries and information institutions. However at present, academic research on knowledge service is falling short and its definition is far from clear and complete. As such,this article proposes the Three-dimensional Framework Knowledge Service(TdFKS) for libraries and information institutions based on the knowledge value chain model. By making reliability analysis and mean value analysis of a questionnaire survey result, the article clarifies the structure of the three-dimensional framework and verifies the rationality of the TdFKS.
文摘Artificial intelligence(AI)is the study of algorithms that enable machines to analyze and execute cognitive activities including problem solving,object and word recognition,reduce the inevitable errors to improve the diagnostic accuracy,and decision-making.Hepatobiliary procedures are technically complex and the use of AI in perioperative management can improve patient outcomes as discussed below.Three-dimensional(3D)reconstruction of images obtained via ultrasound,computed tomography scan or magnetic resonance imaging,can help surgeons better visualize the surgical sites with added depth perception.Preoperative 3D planning is associated with lesser operative time and intraoperative complications.Also,a more accurate assessment is noted,which leads to fewer operative complications.Images can be converted into physical models with 3D printing technology,which can be of educational value to students and trainees.3D images can be combined to provide 3D visualization,which is used for preoperative navigation,allowing for more precise localization of tumors and vessels.Nevertheless,AI enables surgeons to provide better,personalized care for each patient.
文摘Prosthodontics,deals in the restoration and replacement of missing and structurally compromised teeth,this field has been remarkably transformed in the last two decades.Through the integration of digital imaging and threedimensional printing,prosthodontics has evolved to provide more durable,precise,and patient-centric outcome.However,as we stand at the convergence of technology and healthcare,a new era is emerging,one that holds immense promise for the field and that is artificial intelligence(AI).In this paper,we explored the fascinating challenges and prospects associated with the future of prosthodontics in the era of AI.
