Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection,which is clinical problem often faced by intensive care units (ICU) doctors.Without positive treatment,the in...Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection,which is clinical problem often faced by intensive care units (ICU) doctors.Without positive treatment,the incidence and mortality of sepsis are high.^[1]As hospital infection control plays an essential role in treating the nosocomial infections in the ICU,and according to the clinical presentation of critically ill patients,the biological characteristics of pathogenic microorganisms and the ICU environment,this article put forward a strategy for the nosocomial infections in the ICU.展开更多
Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units(ICUs).This abstract provides a concise summary of the latest d...Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units(ICUs).This abstract provides a concise summary of the latest developments in critical care,highlighting key areas of innovation.Recent advancements in critical care include Precision Medicine:Tailoring treatments based on individual patient characteristics,genomics,and biomarkers to enhance the effectiveness of therapies.The objective is to describe the recent advancements in Critical Care Medicine.Telemedicine:The integration of telehealth technologies for remote patient monitoring and consultation,facilitating timely interventions.Artificial intelligence(AI):AI-driven tools for early disease detection,predictive analytics,and treatment optimization,enhancing clinical decision-making.Organ Support:Advanced life support systems,such as Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy provide better organ support.Infection Control:Innovative infection control measures to combat emerging pathogens and reduce healthcare-associated infections.Ventilation Strategies:Precision ventilation modes and lung-protective strategies to minimize ventilatorinduced lung injury.Sepsis Management:Early recognition and aggressive management of sepsis with tailored interventions.Patient-Centered Care:A shift towards patient-centered care focusing on psychological and emotional wellbeing in addition to medical needs.We conducted a thorough literature search on PubMed,EMBASE,and Scopus using our tailored strategy,incorporating keywords such as critical care,telemedicine,and sepsis management.A total of 125 articles meeting our criteria were included for qualitative synthesis.To ensure reliability,we focused only on articles published in the English language within the last two decades,excluding animal studies,in vitro/molecular studies,and non-original data like editorials,letters,protocols,and conference abstracts.These advancements reflect a dynamic landscape in critical care medicine,where technology,research,and patient-centered approaches converge to improve the quality of care and save lives in ICUs.The future of critical care promises even more innovative solutions to meet the evolving challenges of modern medicine.展开更多
High resistance rates to antimicrobials continue to be a global health threat.The incidence of multidrug-resistant(MDR)microorganisms in intensive care units(ICUs)is quite high compared to in the community and other u...High resistance rates to antimicrobials continue to be a global health threat.The incidence of multidrug-resistant(MDR)microorganisms in intensive care units(ICUs)is quite high compared to in the community and other unitsin the hospital because ICU patients are generally older,have higher numbers of co-morbidities and immunesuppressed;moreover,the typically high rates of invasive procedures performed in the ICU increase the risk ofinfection by MDR microorganisms.Antimicrobial stewardship(AMS)refers to the implementation of coordinatedinterventions to improve and track the appropriate use of antibiotics while offering the best possible antibioticprescription(according to dose,duration,and route of administration).Broad-spectrum antibiotics are frequentlypreferred in ICUs because of greater infection severity and colonization and infection by MDR microorganisms.For this reason,a number of studies on AMS in ICUs have increased in recent years.Reducing the use of broadspectrum antibiotics forms the basis of AMS.For this purpose,parameters such as establishing an AMS team,limiting the use of broad-spectrum antimicrobials,terminating treatments early,using early warning systems,pursuing infection control,and providing education and feedback are used.In this review,current AMS practicesin ICUs are discussed.展开更多
目的分析对医护人员实施重症监护病房(intensive care unit,ICU)感染防控管理的效果。方法选取2022年1月—2023年12月在新疆生产建设兵团第九师医院ICU病房工作的21名医护人员作为研究对象,2022年1—12月(对照组)行常规管理,2023年1—12...目的分析对医护人员实施重症监护病房(intensive care unit,ICU)感染防控管理的效果。方法选取2022年1月—2023年12月在新疆生产建设兵团第九师医院ICU病房工作的21名医护人员作为研究对象,2022年1—12月(对照组)行常规管理,2023年1—12月(观察组)行ICU感染防控管理。对比两组医院感染发生情况与感染控制措施执行评分。结果观察组医护人员医院感染发生率为0,低于对照组的9.52%(2/21)。观察组环境控制评分为(95.43±2.23)分、物品消毒评分为(94.23±1.89)分、无菌操作评分为(95.13±3.87)分、手卫生评分为(95.09±3.92)分,均高于对照组的(90.34±3.14)分、(90.87±2.10)分、(90.11±2.87)分、(90.87±3.88)分,差异有统计学意义(t=7.239、6.514、5.707、4.191,P均<0.05)。结论ICU感染防控措施能有效减少医院感染情况,提高医护人员的感染控制措施执行力。展开更多
目的探讨重症监护室(intensive care unit,ICU)住院患者中应用循环质控理念联合风险管理模式的效果。方法选取2023年1—5月寿光市人民医院ICU住院患者335例作为对照组,实施常规医院感染管理;选取2023年6—12月ICU住院患者340例作为干预...目的探讨重症监护室(intensive care unit,ICU)住院患者中应用循环质控理念联合风险管理模式的效果。方法选取2023年1—5月寿光市人民医院ICU住院患者335例作为对照组,实施常规医院感染管理;选取2023年6—12月ICU住院患者340例作为干预组,实施循环质控理念联合风险管理模式。比较2组管理质量、风险事件、医院感染发生率及患者满意度。结果干预组管理质量(感染监测、组织管理、风险评估、制度建设)评分高于对照组(P<0.05);干预组风险事件发生率(1.47%)低于对照组(4.48%)(P<0.05);干预组医院感染发生率(3.82%)低于对照组(7.46%)(P<0.05);干预组患者满意度(98.24%)低于对照组(95.52%)(P<0.05)。结论循环质控理念联合风险管理模式应用于ICU住院患者中,可提高管理质量,减少风险事件与医院感染发生,促进患者满意度提升,体现了《ICU十大安全目标》的执行标准。展开更多
目的探讨长期抗病毒治疗治疗(antiretroviral therapy,ART)的人类免疫缺陷病毒系统评价重症监护室(intensive care unit,ICU)患者多重耐药菌(multi drug resistant organisms,MDRO)感染的影响因素。方法以建库至2024年7月为检索时限,计...目的探讨长期抗病毒治疗治疗(antiretroviral therapy,ART)的人类免疫缺陷病毒系统评价重症监护室(intensive care unit,ICU)患者多重耐药菌(multi drug resistant organisms,MDRO)感染的影响因素。方法以建库至2024年7月为检索时限,计算机检索Ovid、Pub Med、CNKI、Embase、Wan Fang等主要数据库中有关ICU患者MDRO感染的队列研究或病例对照研究,经文献筛选、评价及提取有效数据后,以Rev Man5.3软件行统计分析。结果纳入研究23项,ICU患者共11933例。Meta分析结果显示,感染组与非感染组比较,患者入住ICU天数MD=5.05,z=5.710,P=0.000;住院天数MD=12.62,z=9.160,P=0.000;急性生理及慢性健康评估(acute physiology and chronic health evaluation,APACHE)评分MD=1.78,z=5.820,P=0.000;静脉置管OR=3.600,z=4.570,P=0.000;抗菌药物联用OR=5.540,z=15.330,P=0.000。结论患者入住ICU天数、住院天数、APACHE评分、静脉置管、抗菌药物联用是ICU患者MDRO感染的影响因素,临床需予以重视。展开更多
目的分析风险评估联合计划-执行-检查-处理(plan-do-check-act,PDCA)循环法在多重耐药菌感染(multiple drug-resistant organism,MDRO)防控中的应用效果。方法选取2021年7月—2023年6月菏泽市中医医院重症加强护理病房(intensive care u...目的分析风险评估联合计划-执行-检查-处理(plan-do-check-act,PDCA)循环法在多重耐药菌感染(multiple drug-resistant organism,MDRO)防控中的应用效果。方法选取2021年7月—2023年6月菏泽市中医医院重症加强护理病房(intensive care unit,ICU)收治的患者360例,按照干预时间将2021年7月—2022年6月的180例患者作为对照组,2022年7月—2023年6月的180例患者作为研究组。对照组采取常规管理措施防控MDRO,研究组在其基础上采用风险评估联合PDCA循环法进行MDRO防控。比较2组MDRO防控措施的执行情况与MDRO的检出率。结果研究组的危急值报告、规范隔离、开具隔离医嘱、诊疗用品专用、诊疗时个人防护、手卫生、终末消毒的执行情况评分均高于对照组,差异有统计学意义(P<0.05)。研究组MDRO检出率为5.56%,低于对照组的12.22%(P<0.05)。结论风险评估与PDCA循环法联合应用可以进一步提升MDRO防控工作的执行情况,降低MDRO发生风险。展开更多
文摘Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection,which is clinical problem often faced by intensive care units (ICU) doctors.Without positive treatment,the incidence and mortality of sepsis are high.^[1]As hospital infection control plays an essential role in treating the nosocomial infections in the ICU,and according to the clinical presentation of critically ill patients,the biological characteristics of pathogenic microorganisms and the ICU environment,this article put forward a strategy for the nosocomial infections in the ICU.
文摘Critical care medicine in the 21st century has witnessed remarkable advancements that have significantly improved patient outcomes in intensive care units(ICUs).This abstract provides a concise summary of the latest developments in critical care,highlighting key areas of innovation.Recent advancements in critical care include Precision Medicine:Tailoring treatments based on individual patient characteristics,genomics,and biomarkers to enhance the effectiveness of therapies.The objective is to describe the recent advancements in Critical Care Medicine.Telemedicine:The integration of telehealth technologies for remote patient monitoring and consultation,facilitating timely interventions.Artificial intelligence(AI):AI-driven tools for early disease detection,predictive analytics,and treatment optimization,enhancing clinical decision-making.Organ Support:Advanced life support systems,such as Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy provide better organ support.Infection Control:Innovative infection control measures to combat emerging pathogens and reduce healthcare-associated infections.Ventilation Strategies:Precision ventilation modes and lung-protective strategies to minimize ventilatorinduced lung injury.Sepsis Management:Early recognition and aggressive management of sepsis with tailored interventions.Patient-Centered Care:A shift towards patient-centered care focusing on psychological and emotional wellbeing in addition to medical needs.We conducted a thorough literature search on PubMed,EMBASE,and Scopus using our tailored strategy,incorporating keywords such as critical care,telemedicine,and sepsis management.A total of 125 articles meeting our criteria were included for qualitative synthesis.To ensure reliability,we focused only on articles published in the English language within the last two decades,excluding animal studies,in vitro/molecular studies,and non-original data like editorials,letters,protocols,and conference abstracts.These advancements reflect a dynamic landscape in critical care medicine,where technology,research,and patient-centered approaches converge to improve the quality of care and save lives in ICUs.The future of critical care promises even more innovative solutions to meet the evolving challenges of modern medicine.
文摘High resistance rates to antimicrobials continue to be a global health threat.The incidence of multidrug-resistant(MDR)microorganisms in intensive care units(ICUs)is quite high compared to in the community and other unitsin the hospital because ICU patients are generally older,have higher numbers of co-morbidities and immunesuppressed;moreover,the typically high rates of invasive procedures performed in the ICU increase the risk ofinfection by MDR microorganisms.Antimicrobial stewardship(AMS)refers to the implementation of coordinatedinterventions to improve and track the appropriate use of antibiotics while offering the best possible antibioticprescription(according to dose,duration,and route of administration).Broad-spectrum antibiotics are frequentlypreferred in ICUs because of greater infection severity and colonization and infection by MDR microorganisms.For this reason,a number of studies on AMS in ICUs have increased in recent years.Reducing the use of broadspectrum antibiotics forms the basis of AMS.For this purpose,parameters such as establishing an AMS team,limiting the use of broad-spectrum antimicrobials,terminating treatments early,using early warning systems,pursuing infection control,and providing education and feedback are used.In this review,current AMS practicesin ICUs are discussed.
文摘目的分析对医护人员实施重症监护病房(intensive care unit,ICU)感染防控管理的效果。方法选取2022年1月—2023年12月在新疆生产建设兵团第九师医院ICU病房工作的21名医护人员作为研究对象,2022年1—12月(对照组)行常规管理,2023年1—12月(观察组)行ICU感染防控管理。对比两组医院感染发生情况与感染控制措施执行评分。结果观察组医护人员医院感染发生率为0,低于对照组的9.52%(2/21)。观察组环境控制评分为(95.43±2.23)分、物品消毒评分为(94.23±1.89)分、无菌操作评分为(95.13±3.87)分、手卫生评分为(95.09±3.92)分,均高于对照组的(90.34±3.14)分、(90.87±2.10)分、(90.11±2.87)分、(90.87±3.88)分,差异有统计学意义(t=7.239、6.514、5.707、4.191,P均<0.05)。结论ICU感染防控措施能有效减少医院感染情况,提高医护人员的感染控制措施执行力。
文摘目的探讨重症监护室(intensive care unit,ICU)住院患者中应用循环质控理念联合风险管理模式的效果。方法选取2023年1—5月寿光市人民医院ICU住院患者335例作为对照组,实施常规医院感染管理;选取2023年6—12月ICU住院患者340例作为干预组,实施循环质控理念联合风险管理模式。比较2组管理质量、风险事件、医院感染发生率及患者满意度。结果干预组管理质量(感染监测、组织管理、风险评估、制度建设)评分高于对照组(P<0.05);干预组风险事件发生率(1.47%)低于对照组(4.48%)(P<0.05);干预组医院感染发生率(3.82%)低于对照组(7.46%)(P<0.05);干预组患者满意度(98.24%)低于对照组(95.52%)(P<0.05)。结论循环质控理念联合风险管理模式应用于ICU住院患者中,可提高管理质量,减少风险事件与医院感染发生,促进患者满意度提升,体现了《ICU十大安全目标》的执行标准。
文摘目的探讨长期抗病毒治疗治疗(antiretroviral therapy,ART)的人类免疫缺陷病毒系统评价重症监护室(intensive care unit,ICU)患者多重耐药菌(multi drug resistant organisms,MDRO)感染的影响因素。方法以建库至2024年7月为检索时限,计算机检索Ovid、Pub Med、CNKI、Embase、Wan Fang等主要数据库中有关ICU患者MDRO感染的队列研究或病例对照研究,经文献筛选、评价及提取有效数据后,以Rev Man5.3软件行统计分析。结果纳入研究23项,ICU患者共11933例。Meta分析结果显示,感染组与非感染组比较,患者入住ICU天数MD=5.05,z=5.710,P=0.000;住院天数MD=12.62,z=9.160,P=0.000;急性生理及慢性健康评估(acute physiology and chronic health evaluation,APACHE)评分MD=1.78,z=5.820,P=0.000;静脉置管OR=3.600,z=4.570,P=0.000;抗菌药物联用OR=5.540,z=15.330,P=0.000。结论患者入住ICU天数、住院天数、APACHE评分、静脉置管、抗菌药物联用是ICU患者MDRO感染的影响因素,临床需予以重视。
文摘目的分析风险评估联合计划-执行-检查-处理(plan-do-check-act,PDCA)循环法在多重耐药菌感染(multiple drug-resistant organism,MDRO)防控中的应用效果。方法选取2021年7月—2023年6月菏泽市中医医院重症加强护理病房(intensive care unit,ICU)收治的患者360例,按照干预时间将2021年7月—2022年6月的180例患者作为对照组,2022年7月—2023年6月的180例患者作为研究组。对照组采取常规管理措施防控MDRO,研究组在其基础上采用风险评估联合PDCA循环法进行MDRO防控。比较2组MDRO防控措施的执行情况与MDRO的检出率。结果研究组的危急值报告、规范隔离、开具隔离医嘱、诊疗用品专用、诊疗时个人防护、手卫生、终末消毒的执行情况评分均高于对照组,差异有统计学意义(P<0.05)。研究组MDRO检出率为5.56%,低于对照组的12.22%(P<0.05)。结论风险评估与PDCA循环法联合应用可以进一步提升MDRO防控工作的执行情况,降低MDRO发生风险。
