Background: In new outpatients, blood pressure should be measured in both arms. A previous study reported that an inter-arm systolic blood pressure difference (ΔSBP) of ≥10 mm Hg is associated with an increased risk...Background: In new outpatients, blood pressure should be measured in both arms. A previous study reported that an inter-arm systolic blood pressure difference (ΔSBP) of ≥10 mm Hg is associated with an increased risk of mortality. Aim: The aim was to identify the associations with absolute values of ΔSBP (|ΔSBP|) ≥10 mm Hg. Subjects and Methods: This study included 2481 patients. Patients with a body mass index ≥25 kg/m<sup>2</sup> were defined as obese. The group of A was defined as following: ankle-brachial index (ABI) was <0.9 or ≥1.3. ΔSBP was expressed as right arm BP minus left arm BP. |ΔSBP| ≥10 mm Hg were analyzed using multivariate logistic analysis. Results: |ΔSBP| ≥10 mm Hg was found in 6.0% of patients and |ΔSBP| < 5 mm Hg in 80.4%. In multivariate analysis, the odds ratios (ORs) of the associations with |ΔSBP| ≥10 mm Hg were significantly associated with abnormal ABI and obesity regardless of sex and age. Moreover, the OR of the combined effects of abnormal ABI and obesity was higher than that of abnormal ABI and obesity alone. Conclusion: |ΔSBP| ≥10 mm Hg was associated with abnormal ABI and obesity. In a primary care setting, blood pressure should be actively measured in both arms. This study suggests that the associations with |ΔSBP| ≥10 mm Hg may be a useful part of screening for abnormal ABI.展开更多
目的通过Meta分析来探讨双上肢收缩压差值（IADSBP）与心血管疾病的相关性。方法计算机检索The Cochrane Library、Pub Med、Medline、EMbase、中国知网及万方数据库,检索时间截止至2014年9月30日,查找包含双上肢血压差值与心血管疾病...目的通过Meta分析来探讨双上肢收缩压差值（IADSBP）与心血管疾病的相关性。方法计算机检索The Cochrane Library、Pub Med、Medline、EMbase、中国知网及万方数据库,检索时间截止至2014年9月30日,查找包含双上肢血压差值与心血管疾病相关数据的队列研究、病例对照研究及观察性研究,阅读并严格按照纳入标准筛选,提取数据,通过Revman5.3软件进行Meta分析。结果共纳入7篇文献,8个横断面观察性研究,均为英文文献,共5263例患者,所纳入研究根据IADSBP≥15 mm Hg,〈15 mm Hg分为两组,Meta分析显示：IADSBP≥15 mm Hg组与〈15 mm Hg组冠心病发生率无统计学差异（RR=1.03,95%CI：0.67~1.58,P=0.88）。同步测量亚组分析（RR=0.87,95%CI：0.59~1.30,P=0.51）及非同步测量亚组分析（RR=1.13,95%CI：0.55~2.31,P=0.73）,其结果亦提示IADSBP≥15mm Hg与〈15 mm Hg组冠心病发生率无统计学差异。结论 IADSBP≥15 mm Hg与心血管疾病发病无明显相关性,暂不能较好的作为冠心病的危险预测因素。展开更多
背景臂间收缩压差(IASBPD)与心血管事件发生风险增加有关,这一关系可能由动脉硬化介导。目的探讨IASBPD对原发性高血压患者发生动脉硬化的影响。方法本研究为回顾性研究,连续纳入2019年12月至2021年9月就诊于首都医科大学附属北京安贞...背景臂间收缩压差(IASBPD)与心血管事件发生风险增加有关,这一关系可能由动脉硬化介导。目的探讨IASBPD对原发性高血压患者发生动脉硬化的影响。方法本研究为回顾性研究,连续纳入2019年12月至2021年9月就诊于首都医科大学附属北京安贞医院的6834例原发性高血压患者,根据IASBPD将患者分为三组,以臂踝脉搏波速度(baPWV)数值为动脉硬化判定标准,采用线性回归和Logistic回归模型分析IASBPD对动脉硬化发生的影响。根据回归分析结果,进一步采用多因素Logistic回归进行亚组分析,探讨各影响因素和其交互作用对动脉硬化发生的影响。结果根据IASBPD将患者分为IASBPD<5 mm Hg(n=4248)、5 mm Hg≤IASBPD<10 mm Hg(n=1806)和IASBPD≥10 mm Hg(n=780)三组。原发性高血压患者的中位baPWV为1572(1392,1702)cm/s,按照baPWV>1800 cm/s的标准,动脉硬化患者共1043例(15.26%)。多元线性回归分结果析显示,IASBPD是臂踝脉搏波速度(baPWV)的影响因素,IASBPD每增加1 mm Hg,baPWV增加4.31 cm/s〔B=4.31,95%CI(3.29,5.31),P<0.05〕;多因素Logistic回归分析结果显示,IASBPD≥10 mm Hg是动脉硬化发生的危险因素〔OR=2.28,95%CI(1.76,2.94),P<0.05〕。亚组分析的结果显示,在低密度脂蛋白胆固醇(LDL-C)≥3.4 mmol/L的患者中,IASBPD≥10 mm Hg与动脉硬化风险增加的关系更显著(P=0.021)。结论IASBPD≥10 mm Hg是原发性高血压患者发生动脉硬化的危险因素,在LDL-C≥3.4 mmol/L的患者中更显著。IASBPD可作为一个简单、有效的评估动脉硬化的指标。展开更多
文摘Background: In new outpatients, blood pressure should be measured in both arms. A previous study reported that an inter-arm systolic blood pressure difference (ΔSBP) of ≥10 mm Hg is associated with an increased risk of mortality. Aim: The aim was to identify the associations with absolute values of ΔSBP (|ΔSBP|) ≥10 mm Hg. Subjects and Methods: This study included 2481 patients. Patients with a body mass index ≥25 kg/m<sup>2</sup> were defined as obese. The group of A was defined as following: ankle-brachial index (ABI) was <0.9 or ≥1.3. ΔSBP was expressed as right arm BP minus left arm BP. |ΔSBP| ≥10 mm Hg were analyzed using multivariate logistic analysis. Results: |ΔSBP| ≥10 mm Hg was found in 6.0% of patients and |ΔSBP| < 5 mm Hg in 80.4%. In multivariate analysis, the odds ratios (ORs) of the associations with |ΔSBP| ≥10 mm Hg were significantly associated with abnormal ABI and obesity regardless of sex and age. Moreover, the OR of the combined effects of abnormal ABI and obesity was higher than that of abnormal ABI and obesity alone. Conclusion: |ΔSBP| ≥10 mm Hg was associated with abnormal ABI and obesity. In a primary care setting, blood pressure should be actively measured in both arms. This study suggests that the associations with |ΔSBP| ≥10 mm Hg may be a useful part of screening for abnormal ABI.
文摘目的通过Meta分析来探讨双上肢收缩压差值（IADSBP）与心血管疾病的相关性。方法计算机检索The Cochrane Library、Pub Med、Medline、EMbase、中国知网及万方数据库,检索时间截止至2014年9月30日,查找包含双上肢血压差值与心血管疾病相关数据的队列研究、病例对照研究及观察性研究,阅读并严格按照纳入标准筛选,提取数据,通过Revman5.3软件进行Meta分析。结果共纳入7篇文献,8个横断面观察性研究,均为英文文献,共5263例患者,所纳入研究根据IADSBP≥15 mm Hg,〈15 mm Hg分为两组,Meta分析显示：IADSBP≥15 mm Hg组与〈15 mm Hg组冠心病发生率无统计学差异（RR=1.03,95%CI：0.67~1.58,P=0.88）。同步测量亚组分析（RR=0.87,95%CI：0.59~1.30,P=0.51）及非同步测量亚组分析（RR=1.13,95%CI：0.55~2.31,P=0.73）,其结果亦提示IADSBP≥15mm Hg与〈15 mm Hg组冠心病发生率无统计学差异。结论 IADSBP≥15 mm Hg与心血管疾病发病无明显相关性,暂不能较好的作为冠心病的危险预测因素。
文摘背景臂间收缩压差(IASBPD)与心血管事件发生风险增加有关,这一关系可能由动脉硬化介导。目的探讨IASBPD对原发性高血压患者发生动脉硬化的影响。方法本研究为回顾性研究,连续纳入2019年12月至2021年9月就诊于首都医科大学附属北京安贞医院的6834例原发性高血压患者,根据IASBPD将患者分为三组,以臂踝脉搏波速度(baPWV)数值为动脉硬化判定标准,采用线性回归和Logistic回归模型分析IASBPD对动脉硬化发生的影响。根据回归分析结果,进一步采用多因素Logistic回归进行亚组分析,探讨各影响因素和其交互作用对动脉硬化发生的影响。结果根据IASBPD将患者分为IASBPD<5 mm Hg(n=4248)、5 mm Hg≤IASBPD<10 mm Hg(n=1806)和IASBPD≥10 mm Hg(n=780)三组。原发性高血压患者的中位baPWV为1572(1392,1702)cm/s,按照baPWV>1800 cm/s的标准,动脉硬化患者共1043例(15.26%)。多元线性回归分结果析显示,IASBPD是臂踝脉搏波速度(baPWV)的影响因素,IASBPD每增加1 mm Hg,baPWV增加4.31 cm/s〔B=4.31,95%CI(3.29,5.31),P<0.05〕;多因素Logistic回归分析结果显示,IASBPD≥10 mm Hg是动脉硬化发生的危险因素〔OR=2.28,95%CI(1.76,2.94),P<0.05〕。亚组分析的结果显示,在低密度脂蛋白胆固醇(LDL-C)≥3.4 mmol/L的患者中,IASBPD≥10 mm Hg与动脉硬化风险增加的关系更显著(P=0.021)。结论IASBPD≥10 mm Hg是原发性高血压患者发生动脉硬化的危险因素,在LDL-C≥3.4 mmol/L的患者中更显著。IASBPD可作为一个简单、有效的评估动脉硬化的指标。
