AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sect...AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD.展开更多
Qiaoxi Poems is an influential collection of poetry that reflects the integration of the Zhuang and Han ethnic groups in China.It has collected a considerable number of Zhuang and Han Chinese poems on an unprecedented...Qiaoxi Poems is an influential collection of poetry that reflects the integration of the Zhuang and Han ethnic groups in China.It has collected a considerable number of Zhuang and Han Chinese poems on an unprecedented scale,featuring poems that blend ancient Zhuang and Han characters,showing the historical memory of exchanges and integration between the Zhuang and Han people,and reflecting their common spiritual home.Qiaoxi poetry has spread to the United States,where it is collected in the Harvard-Yenching Library and the East Asia Library at Columbia University.This is a reflection of its widespread spread.Qiaoxi Poems are of great value to the study of the development of Chinese poetry in Guangxi during the Ming and Qing Dynasties.展开更多
Risk of clinically significant prostate adenocarcinoma （CAP） varies worldwide,although there is a uniform prevalence of latent disease. A hormone-responsive tissue,the prostate possesses the metabolizing capacity to...Risk of clinically significant prostate adenocarcinoma （CAP） varies worldwide,although there is a uniform prevalence of latent disease. A hormone-responsive tissue,the prostate possesses the metabolizing capacity to biotransform a variety of environmental procarcinogens or endogenous hormones. Whether such metabolizing capacity or estrogen receptor （ER） status underlies these demographic differences in susceptibility to CaP remains unclear. With appropriate ethical permission,verified-benign tissues were obtained following transurethral resection of the prostate from a high-risk region （n = 12 UK-resident Caucasians） and a typically low-risk region （n = 14 India-resident Asians）. Quantitative gene expression analysis was employed for cytochrome P450 （CYP）1B1,N-acetyltransferase （NAT）1,NAT2,catechol-O-methyl transferase （ COMT）,sulfotransferase （ SULT） 1A1,ERα,ERβ and aromatase （CYP To quantify the presence or absence of CYP1B1,ERα or ERβ,and to identify ther in situ localization,immunohistochemistry was carried out. The two cohorts had reasonably well-matched serum levels of prostate-specific antigen or hormones. Expression levels for the candidate genes investigated were similar.However,clear differences in protein levels for CYP1B1 and ERβ were noted. Staining for CYP1B1 tended to be nuclear-associated in the basal glandular epithelial cells,and in UK-resident Caucasian tissues was present at a higher （P = 0.006） level compared with that from India-resident Asians. In contrast,a higher level of positive ERβ staining was noted in prostates from India-resident Asians. These study findings point to differences in metabolizing capacity and ER status in benign prostate tissues that might modulate susceptibility to the emergence of clinically significant CaP in demographically distinct populations.展开更多
In almost a century of its development,Chinese ethnology has gradually formed some significant academic paradigms.One of them is the"ethnic research paradigm"which concentrates on summarizing,organizing,and ...In almost a century of its development,Chinese ethnology has gradually formed some significant academic paradigms.One of them is the"ethnic research paradigm"which concentrates on summarizing,organizing,and detailing social and cultural facts using"ethnicity"as its primary unit.This paradigm sees ethnicity as its foundational unit of study.Meanwhile,the"inter-ethnic research paradigm"transcends singular ethnic groups,spotlighting the complex interactions between multiple ethnic groups.It views a multi-ethnic community or region as its core research field,underscoring the nuances of cultural exchange,overlap,and shared experiences.These two paradigms,while distinct,are both invaluable to Chinese ethnology.They don't replace each other but rather work synergistically.Pioneering ethnologist,Fei Xiaotong,masterfully merged these paradigms in his groundbreaking"pluralism and unity"theory,ushering in a refreshed framework for Chinese ethnological studies.This article delves into these foundational paradigms from a historical academic lens,aiming to further refine and enrich the scientific methodologies employed in Chinese ethnology.展开更多
文摘AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD.
文摘Qiaoxi Poems is an influential collection of poetry that reflects the integration of the Zhuang and Han ethnic groups in China.It has collected a considerable number of Zhuang and Han Chinese poems on an unprecedented scale,featuring poems that blend ancient Zhuang and Han characters,showing the historical memory of exchanges and integration between the Zhuang and Han people,and reflecting their common spiritual home.Qiaoxi poetry has spread to the United States,where it is collected in the Harvard-Yenching Library and the East Asia Library at Columbia University.This is a reflection of its widespread spread.Qiaoxi Poems are of great value to the study of the development of Chinese poetry in Guangxi during the Ming and Qing Dynasties.
文摘Risk of clinically significant prostate adenocarcinoma （CAP） varies worldwide,although there is a uniform prevalence of latent disease. A hormone-responsive tissue,the prostate possesses the metabolizing capacity to biotransform a variety of environmental procarcinogens or endogenous hormones. Whether such metabolizing capacity or estrogen receptor （ER） status underlies these demographic differences in susceptibility to CaP remains unclear. With appropriate ethical permission,verified-benign tissues were obtained following transurethral resection of the prostate from a high-risk region （n = 12 UK-resident Caucasians） and a typically low-risk region （n = 14 India-resident Asians）. Quantitative gene expression analysis was employed for cytochrome P450 （CYP）1B1,N-acetyltransferase （NAT）1,NAT2,catechol-O-methyl transferase （ COMT）,sulfotransferase （ SULT） 1A1,ERα,ERβ and aromatase （CYP To quantify the presence or absence of CYP1B1,ERα or ERβ,and to identify ther in situ localization,immunohistochemistry was carried out. The two cohorts had reasonably well-matched serum levels of prostate-specific antigen or hormones. Expression levels for the candidate genes investigated were similar.However,clear differences in protein levels for CYP1B1 and ERβ were noted. Staining for CYP1B1 tended to be nuclear-associated in the basal glandular epithelial cells,and in UK-resident Caucasian tissues was present at a higher （P = 0.006） level compared with that from India-resident Asians. In contrast,a higher level of positive ERβ staining was noted in prostates from India-resident Asians. These study findings point to differences in metabolizing capacity and ER status in benign prostate tissues that might modulate susceptibility to the emergence of clinically significant CaP in demographically distinct populations.
文摘In almost a century of its development,Chinese ethnology has gradually formed some significant academic paradigms.One of them is the"ethnic research paradigm"which concentrates on summarizing,organizing,and detailing social and cultural facts using"ethnicity"as its primary unit.This paradigm sees ethnicity as its foundational unit of study.Meanwhile,the"inter-ethnic research paradigm"transcends singular ethnic groups,spotlighting the complex interactions between multiple ethnic groups.It views a multi-ethnic community or region as its core research field,underscoring the nuances of cultural exchange,overlap,and shared experiences.These two paradigms,while distinct,are both invaluable to Chinese ethnology.They don't replace each other but rather work synergistically.Pioneering ethnologist,Fei Xiaotong,masterfully merged these paradigms in his groundbreaking"pluralism and unity"theory,ushering in a refreshed framework for Chinese ethnological studies.This article delves into these foundational paradigms from a historical academic lens,aiming to further refine and enrich the scientific methodologies employed in Chinese ethnology.
