Specificity and sensitivity of visual evoked potentials P100 latency to different events exercise

Visual evoked potentials (VEPs) are a series of signals about visual occipital cortex in response to visual stimuli and can be used as one of ob-jective non-invasive neuro-physiological pa-rameters to reflect the visual organs and central visual pathway’s functional integrity. Previous studies have shown that acute and chronic ex-ercise could affect VEPs independent from body temperature and other physiological parameters. VEPs may well be used as neuro-physiological criteria in defining the performances of the ath-letes. Different sports training have different effects on VEPs, but the results are not consis-tent. P100 latency is the representative compo-nent of VEPs and it is of high, steady amplitude and of slight intra- and inter-individual variabil-ity so that the index is most commonly used. The purpose of this study was to investigate the specificity and sensitivity of P100 latency to dif-ferent physical activities. The neural electricity device of NDI-200 was used to measure the pattern reversal VEPs of all subjects, including the values of the resting state before and after different events exercise. Different events exer-cise contained an aerobic cycloergometric ex-ercise (7 subjects were conducted to a Bruce Graded Exercise Test on the Monark Ergomedic 839E cycloergometer, THR (target heart rate) = 85% HRmax, 3 times/week, about 10 minutes once time, 6 weeks), tennis training (16 volun-teers, 2 hours/day, 3 days/week, 8 weeks), aerobic Latin exercise (7 subjects, 1 hour/day, 3 days/week, 6 weeks) and the Baduanjin of Health Qigong training (6 subjects, 1 hour/day, 3 days/week, 6 weeks). The VEPs recordings of the control groups obtained synchronized with the experimental groups. SPSS 11.5 for win-dows was used for statistical analysis. A level of P﹤0.05 was accepted as statistically significant. The VEPs P100 latency of post-exercise of all experimental groups except Baduanjin group became shorter significantly compared with those of pre-exercise (P﹤0.05). No significant difference was found between pre-and post- exercise for the control groups. This study showed that exercise could shorten the P100 la-tency significantly. Moreover, it also indicated that VEPs were sensitive to exercise to a certain extent. We concluded that VEPs might well be used as neuro-physiological criteria in defining the performances of the athletes. It was found that the VEPs P100 latency became shorter after most training programs;furthermore, it demon-strated that P100 latency of VEPs had little specificity to different events.

Benefits of combination of electroencephalography, short latency somatosensory evoked potentials, and transcranial Doppler techniques for confirming brain death

Objective: Optimization of combining electroencephalography (EEG), short latency somatosensory evoked potentials (SLSEP) and transcranial Doppler (TCD) techniques to diagnose brain death. Methods: One hundred and eleven patients (69 males, 42 females) from the major hospitals of Zhejiang Province were examined with portable EEG, SLSEP and TCD devices. Re-examinations occurred ≤12 h later. Results: The first examination revealed that the combination of SLSEP and EEG led to more sensitive diagnoses than the combination of SLSEP and TCD. Re-examination confirmed this and also revealed that the combination of TCD and EEG was the most sensitive. Conclusion: The results show that using multiple techniques to diagnose brain death is superior to using single method, and that the combination of SLSEP and EEG is better than other combinations.

THE PEAK LATENCY OF ORBITAL PRESACCADIC SPIKE POTENTIAL WITH HORIZONTAL EYE MOVEMENTS

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Changes in the latencies of visual-evoked potentials in people undergoing tennis training Dynamic comparison before and after 8 weeks training

BACKGROUND： Some previous studies have shown that exercise is an important factor that affects the latencies of visual-evoked potentials （VEPs）. OBJECTIVE： To investigate the effects of spending a period of time undergoing tennis training on the latencies of VEPs by comparing the latencies of VEPs before tennis training with those after 8 weeks of tennis training. DESIGN, TIME AND SETTING： The non-randomly concurrent controlled experiment was performed in the Department of Human Movement Sciences, Physical Education College, Shandong Normal University from April to June 2007. PARTICIPANTS： In total, 45 healthy volunteers from Shandong Normal University were selected as subjects, including 31 students majoring in physical education （11 males and 5 females participated in the tennis training plan for 8 weeks）, and 14 students from other subjects. Informed consent was obtained. According to whether they were majoring in physical education or not, and whether or not they took part in tennis training, the students were divided into 3 groups： a tennis group of physical education students （n = 16） a non-tennis group of physical education students （n =15） and a non-tennis group of non-physical education students （n = 14）. METHODS： The subjects in the tennis group took part in a regular tennis training plan of 2 hours a day and 3 days per week, for 8 weeks, while the subjects in two non-tennis groups were not in the tennis training plan The NDI-200 neural electricity tester （Shanghai Haishen Medical Electronic Instrument Co., Ltd.） was used to measure VEPs before and after the experiment in all three groups, and to compare the latencies of VEPs recorded before training with those recorded after training. MAIN OUTCOME MEASURES： Comparison of the changes in latencies of VEPs before and after 8 weeks of tennis training. RESULTS： All 45 subjects finished the test and datas from all were included in the statistical analysis. There were no significant differences among all the three groups before tennis training, but the female subjects in each group showed significantly shorter N75 latencies than male subjects of the same group （P 〈 0.05）. Comparing the latencies of VEPs after training with those recorded before training, the N75, P100 and N145 latencies were all found to be significantly shorter than before training in the tennis group （P 〈 0.05）, but the N75, P100 and N145 latencies were unaffected in the two non-tennis groups （P 〉 0.05）; some latencies were even significantly longer than the before-training values. CONCLUSION： Special tennis training for 8 weeks can make the subjects＇ VEP latencies significantly shorter. Thus, VEP latencies can change with tennis training.

Monitoring somatosensory evoked potentials in spinal cord ischemia-reperfusion injury

It remains unclear whether spinal cord ischemia-reperfusion injury caused by ischemia and other non-mechanical factors can be monitored by somatosensory evoked potentials. Therefore, we monitored spinal cord ischemia-reperfusion injury in rabbits using somatosensory evoked potential detection technology. The results showed that the somatosensory evoked potential latency was significantly prolonged and the amplitude significantly reduced until it disappeared during the period of spinal cord ischemia. After reperfusion for 30-180 minutes, the amplitude and latency began to gradually recover; at 360 minutes of reperfusion, the latency showed no significant difference compared with the pre-ischemic value, while the somatosensory evoked potential amplitude in- creased, and severe hindlimb motor dysfunctions were detected. Experimental findings suggest that changes in somatosensory evoked potentia~ ~atency can reflect the degree of spinat cord ischemic injury, while the amplitude variations are indicators of the late spinal cord reperfusion injury, which provide evidence for the assessment of limb motor function and avoid iatrogenic spinal cord injury.

Cortical evoked potential changes in a rat model of acute ischemic stroke Detection of somatosensory evoked potential and motor evoked potential

BACKGROUND： Studies have shown that latency changes of some elements in a somatosensory evoked potential （SEP） and motor evoked potential （MEP） can reflect electrical activity of cerebral cortical neurons and conduction of white matter nerve fibers. However, there is a paucity of information regarding the dynamic observation of SEP and MEP following cerebral ischemic injury. OBJECTIVE： To explore SEP and MEP changes following acute ischemic stroke, and investigate the role of evoked potentials in monitoring brain function in stroke. DESIGN, TIME AND SETTING： A randomized, controlled, animal experiment was performed at the Chongqing Key Laboratory of Neurology, Affiliated Hospital of Chongqing Medical University from September 2007 to August 2008. MATERIALS＂ Hydrogen blood flow detector was purchased from Soochow University Medical Instrument Co., China, and Power lab system was purchased from AD Instruments, Inc., USA. METHODS A total of 36 healthy, adult, male, Sprague Dawley rats were randomly assigned to four groups （n = 9）, including three ischemia groups （12, 24 and 72 hours of ischemia） and a sham-surgery group. The rat model of acute ischemic stroke was established by middle cerebral artery occlusion （MCAO） in the left hemisphere. MAIN OUTCOME MEASURES＂ SEP and MEP of the left limbs were detected, and cerebral blood flow was measured by the hydrogen cleaning method. RESULTS： The latency of positive wave 1 （P1）, negative wave 1 （N1） and positive wave 2 （P2） waves in SEP, and latency of negative wave 1,2 （N1, N2） waves in MEP were significantly prolonged with increasing ischemic duration following MCAO （P 〈 0.01）, but cerebral blood flow was significantly decreased （P 〈 0.05, or P 〈 0.01）. CONLUSION： Ischemic stroke prolongs the latency of SEP waves （P1, N1, P2） and MEP waves （N1, N2）, and cerebral cortical evoked potential may correlate with cerebral blood flow changes. This indicates that SEP and MEP can be used to evaluate brain function following acute ischemic stroke.

Characteristics of brainstem auditory evoked potentials of students studying folk dance

BACKGROUND： Previous experiments have demonstrated that brainstem auditory evoked potential is affected by exercise, exercise duration, and frequency. OBJECTIVE： Comparing the brainstem auditory evoked potential of students studying folk dance to students studying other subjects. DESIGN： Observational contrast study. SETTING： Physical Education College, Shandong Normal University PARTICIPANTS： Fifty-five female students were enrolled at Shandong Normal University between September and December in 2005, including 21 students that studied folk dance and 34 students that studied other subjects. The age of the folk dance students averaged （19 ± 1） years and dance training length was （6.0 ± 1.5） years. The students that studied other subjects had never taken part in dance training or other physical training, and their age averaged （22 ± 1） years, body height averaged （162 ± 5） cm, body mass averaged （51 ± 6） kg. All subjects had no prior ear disease or history of other neurological disorders. All students provided informed consent for the experimental project. METHODS： The neural electricity tester, NDI-200 （Shanghai Poseidon Medical Electronic Instrument Factory） was used to examine and record Brainstem Auditory Evoked Potential values of the subjects during silence, as well as to transversally analyze the Brainstem Auditory Evoked Potential values. The electrode positions were cleaned and degreased with soapy water, followed by ethanol. The selected bipolar electrodes were situated on the head： recording electrodes were placed at the Baihui acupoint, and the reference electrode was placed at the mastoid of the measured ear, with grounding electrodes in the center of the forehead. Brainstem Auditory Evoked Potential values were elicited by monaural stimulation of a ＂click＂ though an earphone; the other ear was sheltered by the white noise. The click intensity was 102 db, the stimulation frequency was 30 Hz, the bandpass filters were 1 000-3 000 Hz, the sensitivity was 5 ta V, and a total of 2 000 sweeps were averaged. Waveform identification and analysis： various components of the Brainstem Auditory Evoked Potential values were identified, and the peak latencies and peak-peak values were analyzed. MAIN OUTCOME MEASURES： Latency of Ⅰ , Ⅱ, Ⅲ, Ⅳ, Ⅴ and Peak-Peak Value of Ⅰ, Ⅲ, Ⅴwere measured. RESULTS： Fifty-five subjects were enrolled in the final analysis, without any loss. Compared to the students who studied other subjects ① Ⅰ -Ⅴ peak latencies （PL）： Ⅳ PL of the right ear of the folk dance students was obviously longer （P 〈 0.05）; ② Ⅰ, Ⅲ, V peak-peak values：Ⅰ peak-peak values of the right ear were obviously higher （P 〈 0.05）. CONCUSION： ① PL of the right ear of the folk dance students was obviously longer, which indicates that dancing results in a stronger sensibility to auditory stimuli. ②. Peak-peak values were obviously higher, which indicates that long-term exercise enhances the music senses and synchrony of auditory nerve impulses.

MOTOR EVOKED POTENTIAL OF MAGNETIC STIMULATION IN THE DETERMINATION OF S_1 RADICULOPATHY

Motor evoked potentlal (MEP) elicited by magnetic stimulation was utilised to diagnose S1 radiculopathy non-invasively. Magnetic stimulation estimated motor nerve conduction time (MNCT), which was used in combination with F response recorded from soleus, allowed calculation of motor root conduction time (MRCT). 50 healthy controls and 30 patients with S1 radiculopathy were studied- The results showed that no difference was seen in MNCT in all patients, but MRCT were markedly prolonged in 87% of the patients, which was higher than the prolongation of F wave latency in 71% or the patients. it is concluded that MEP of magnetic stimulation is a useful technique for non-invasive diagnosis of S, radiculopathy.

A translational study of somatosensory evoked potential time–frequency components in rats,goats,and humans

Somatosensory evoked potentials(SEPs)have been widely used to assess neurological function in clinical practice.A good understanding of the association between SEP signals and neurological function is helpful for precise diagnosis of impairment location.Previous studies on SEPs have been reported in animal models.However,few studies have reported the relationships between SEP waveforms in animals and those in humans.In this study,we collected normal SEP waveforms and decomposed them into specific time–frequency components(TFCs).Our results showed three stable TFC distribution regions in intact goats and rats and in humans.After we induced spinal cord injury in the animal models,a greater number of small TFC distribution regions were observed in the injured goat and rat groups than in the normal group.Moreover,there were significant correlations(P<0.05)and linear relationships between the main SEP TFCs of the human group and those of the goat and rat groups.A stable TFC distribution of SEP components was observed in the human,goat and rat groups,and the TFC distribution modes were similar between the three groups.Results in various animal models in this study could be translated to future clinical studies based on SEP TFC analysis.Human studies were approved by the Institutional Review Board of the University of Hong Kong/Hospital Authority Hong Kong West Cluster(approval No.UM 05-312 T/975)on December 5,2005.Rat experiments were approved by the Committee on the Use of Live Animals in Teaching and Research of Li Ka Shing Faculty of Medicine of the University of Hong Kong(approval No.CULART 2912-12)on January 28,2013.Goat experiments were approved by the Animal Ethics Committee of Affiliated Hospital of Guangdong Medical University(approval No.GDY2002132)on March 5,2018.

The Changes of Pattern Reversal Visual Evoked Potentials in Normal Infants

Purpose:To study pattern reversal visual evoked potential(PVEPs)and deter-mine the developmental character and mature time of visual function in normal in-fants t different months of age.Methods:PVEPs were recorded from115normal infants at3,6,9,12moths age.P1latency for different checks(1°40′，25′，6′）was analyzed and compared to those of normal adults,Changes of N1,N2latency of PVEPs were also exam-ioned.Results:P1 latency for all checks(1°40′,25′，6′）was significantly longer at 3months than at 6months of age(P<0.05),but no significant differences can be seen after 6months of age for largen(1°40′）and intermediate(25′）checks(P>0.05).P1latency for larger checks(1°40′）reached adult level after 3months of age,but not for the intermediate check(25′）,while P1latency for small check(6′）presented the character of fluctuation.Conclusion:The visual system continued to develop after birth and appeared a certain regularity,Our results showed thatP1latency for larger check(1°40′）reached adult levels after 3months of age.ButP1latency for intermediate check still has not reached adult levels after 3months of age.To deterine the age at which adult levels are finally reached,infants of 12months and older must be tested.The reason why P1latency for smaller check(6′）presented the character of fluctuation should be the temporal tuning function developing much more slowly.Eye Science1995;11:161-164.

听觉重塑中时间因素对人工耳蜗植入后电诱发中潜伏期反应的影响分析

目的 对影响人工耳蜗植入后电诱发中潜伏期反应(electrically evoked auditory middle latency response,EMLR)的时间因素,包括植入时年龄、植入后时间及现年龄等进行分析研究,探究听觉重塑过程中不同时间因素的影响。方法 对46例2008年~2014年在北京大学第三医院耳鼻咽喉科进行人工耳蜗植入的患者在术后进行EMLR测试。比较语前聋儿童与语后聋成人EMLR的差异,以及语前聋儿童中现年龄、植入时年龄及植入后时间等因素对EMLR的影响。结果 语前聋儿童EMLR各波潜伏期及波间潜伏期普遍较成人组长,各波间幅值普遍较成人组大,其中Po、Na、Pa、Nb及Pb波潜伏期,PoNa、NaPa及PaNb波间潜伏期,PoNa、NaPa、PaNb及NbPb波间幅值均存在统计学差异(P<0.05)。语前聋儿童中,Pa、Nb波潜伏期及NaPa波间期与现年龄及植入后时间存在显著负相关、与植入时年龄存在显著正相关(P<0.05)。结论 EMLR在语前聋儿童与语后聋成人存在较显著差异,对于语前聋儿童,较大的年龄、较长的植入时间、较小的植入年龄对应更为成熟的EMLR波形,提示上述因素在听觉重塑过程中的重要性。

精神分裂症暴力攻击行为与P300成分的相关性研究

目的探讨精神分裂症患者其暴力攻击行为与事件相关电位P300成分的相关性。方法将2020年12月—2022年12月福建省福州神经精神病防治院精神科精神分裂症住院患者根据其既往个人史及修改版外显攻击量表(modified overt aggression scales,MOAS)评分划分暴力攻击组30例及对照组31例。对比2组一般资料、P300成分的波幅和潜伏期;以及P300成分的波幅和潜伏期与MOAS评分的相关性分析。结果精神分裂症患者中暴力攻击组与对照组一般资料差异无统计学意义(P>0.05);但所诱发的P300成分波幅和潜伏期差异有统计学意义(P<0.05),其中,暴力攻击组其P300成分波幅降低(2.818±0.643)μV,潜伏期延长(335.530±20.664)ms。经Pearson相关分析,精神分裂症患者所诱发的P300成分潜伏期与MOAS评分呈正相关(r=0.580,P<0.05),而其所诱发的P300成分波幅与MOAS评分呈负相关(r=-0.421,P<0.05)。结论具有暴力攻击行为的精神分裂症患者存在更严重的脑认知功能损伤。本研究推测,事件相关电位P300成分的波幅和潜伏期可作为预测及评估精神分裂症暴力攻击行为的电生理指标。

等速肌力训练对脑卒中后偏瘫患者上肢的影响

目的探究等速肌力训练对脑卒中后偏瘫患者上肢的影响。方法选取2022-07—2023-07石家庄市人民医院收治的99例脑卒中后偏瘫患者,采用随机数字法分为常规组49例和观察组50例,常规组给予常规康复治疗,观察组在常规康复治疗基础上给予等速肌力训练。比较训练前和训练4周后,2组患者运动皮层兴奋性[患侧半球运动诱发电位(MEP)潜伏期、中枢运动传导时间(CMCT)]、手力量、生活自理能力[改良Barthel指数量表(MBI)]。结果训练4周后,2组患者MEP、CMCT较训练前降低,观察组MEP[(14.57±1.25)ms]、CMCT[(8.29±1.03)ms]低于常规组[(15.86±1.32)ms、(8.96±1.06)ms](P<0.05);2组患者握力及MBI评分均较训练前升高,观察组握力[(22.42±2.38)kg]、MBI评分[(62.78±6.33)分]高于常规组[(20.15±2.24)kg及(60.17±6.21)分](均P<0.05)。结论等速肌力训练能够改善运动皮层兴奋性,增强手力量,提高生活自理能力。

LATENCY-ALIGNED AVERAGE METHOD FOR EVOKED POTENTIALS

It is well known that averaging is an effective method for extracting the periodic signals which are submerged in the background-noises. The Time-locked Average (TLA) with reference to the stimulated time has been a traditional way to pick up the evoked potentials from the EEG background. The premise of TLA method supposes that the latencies of evoked peaks appear relatively regular as compared with the time of stimulus. But experiment results and clinical observations tell us that the latencies of evoked potentials are not invariant rigidly after stimulations. Hence, the TLA method cannot perfectly reconstruct

正常听力儿童事件相关电位P1波及失匹配负波随年龄的变化规律

目的 探究正常听力儿童事件相关电位(event related potential,ERP)中P1波及失匹配负波(mismatch negativity,MMN)随年龄增长的变化规律以及听觉皮层的发育情况。方法 招募2~11岁儿童,在排除听力问题后,于隔声室内静坐进行听觉诱发电位测试。分析随年龄变化P1波以及MMN的振幅和潜伏期的发展趋势。结果 P1波以及MMN的潜伏期均与儿童年龄增长存在显著负相关,P1波的潜伏期在各年龄组间比较存在显著性差异,而MMN的潜伏期仅在2~3岁小龄组存在显著性延后。结论 伴随儿童年龄的增长,由言语声诱发的P1波和MMN的潜伏期存在逐渐缩短的趋势,听觉皮层的功能不断发育,因此在临床听觉康复中的效果应根据年龄进行评估。

新生儿ABO血型不合溶血病和G6PD致高胆红素血症患儿脑干听觉诱发电位筛查及其临床意义

目的探讨新生儿ABO血型不合溶血病和红细胞内葡萄糖-6-磷酸脱氢酶缺乏症(G6PD)致高胆红素血症患儿脑干听觉诱发电位筛查的临床意义。方法选取2017年4月—2022年3月海南省人民医院收治的151例ABO血型不合溶血病和G6PD致高胆红素血症患儿为研究对象。所有患儿入院后均行脑干听觉诱发电位筛查,记录其Ⅴ波潜伏期耳间差值(ILD)。分析研究组不同病情严重程度患儿Ⅴ波ILD情况,分析影响ABO血型不合溶血病和G6PD致高胆红素血症患儿听力损伤的因素,Ⅴ波ILD诊断ABO血型不合溶血病和G6PD致高胆红素血症患儿听力情况的价值。结果重症组脑干听觉诱发电位Ⅴ波ILD高于轻症组(P<0.05)。多因素Logistic回归分析显示:酸中毒[O^R=4.943(95%CI:2.034,12.013)]、TSB[O^R=5.078(95%CI:2.090,12.342)]、UCB[O^R=5.109(95%CI:2.102,12.417)]、Ⅴ波ILD[O^R=4.614(95%CI:1.898,11.212)]是影响ABO血型不合溶血病和G6PD致高胆红素血症患儿听力的影响因素(P<0.05)。ROC曲线分析结果显示,脑干听觉诱发电位Ⅴ波ILD诊断ABO血型不合溶血病和G6PD致高胆红素血症患儿听力损伤的敏感性为73.33%(95%CI:0.538,0.870),特异性为84.30%(95%CI:0.763,0.901),AUC为0.820(95%CI:0.725,0.915)。结论ABO血型不合溶血病和G6PD致高胆红素血症患儿病情与脑干听觉诱发电位筛查的Ⅴ波ILD有关,Ⅴ波ILD诊断患儿听力损伤效能良好。

针刀联合雷火灸对腰椎间盘突出症患者神经传导的影响观察

目的 探究小针刀联合雷火灸对腰椎间盘突出症引起的神经根性疼痛的临床疗效。方法 将中山陈星海医院收治的56例腰椎间盘突出症患者以随机数字表法分为对照组(29例)与治疗组(27例),对照组单纯使用雷火灸治疗,治疗组在对照组基础上联合小针刀治疗。对比2组患者治疗前后VAS、JOA评分,股神经、腓总神经及胫神经的动作电位潜伏期、MCV以及SCV,临床疗效。结果 2组患者治疗前相关神经的动作电位潜伏期、MCV以及SCV及VAS、JOA评分比较,差异无统计学意义(P>0.05);治疗后VAS评分均较治疗前降低,且治疗组降低更显著(P<0.05),2组JOA评分均较治疗前升高,且治疗组升高更显著(P<0.05),2组腓总神经、胫神经以及股神经动作电位潜伏期均较治疗前缩短,且治疗组缩短更显著(P<0.05),2组腓总神经、胫神经以及股神经MCV以及SCV均较治疗前加快,且治疗组加快更显著(P<0.05)。治疗组总有效率高于对照组(P<0.05)。结论 小针刀联合雷火灸能能明显减轻腰部症状,改善腰椎活动功能,有效恢复腓总神经、胫神经、股神经传导速度,治疗LDH临床疗效较好。

针灸联合表情肌功能康复训练治疗面神经麻痹的疗效及对面神经功能恢复的影响

目的:探讨针灸联合表情肌功能康复训练对面神经麻痹患者的疗效及面神经功能恢复的影响。方法:选择2016年1月~2021年3月安徽天长市中医院收治的60例面神经麻痹患者为研究对象,随机均分为对照组和观察组,对照组给予针灸治疗,观察组采用针灸联合表情肌功能康复训练,两组均治疗4周。比较两组临床疗效、治疗前后患侧面神经肌电检测[面神经复合肌肉动作电位(CMAP)波幅、瞬目反射R1潜伏期、肌电图运动单位束颤波发生率]、简易面神经功能评价量表(SFGS)评分及不良反应发生情况。结果:观察组治疗总有效率96.67%,高于对照组的80.00%(P<0.05);与治疗前比较,治疗后两组CMAP波幅均升高,且观察组高于对照组(P<0.05);与治疗前比较,治疗后两组R1潜伏期及束颤波发生率均降低,且观察组R1潜伏期短于对照组(P<0.05);治疗后两组束颤波发生率比较无统计学差异(P>0.05);与治疗前比较,治疗后两组SFGS量表中眼裂闭合评分、口角偏斜评分均降低,且观察组低于对照组(P<0.05)。治疗期间及治疗后两组均无明显不良反应发生。结论:针灸联合表情肌功能康复训练对面神经麻痹患者疗效显著,可明显改善患者的相关症状与体征,有效恢复患者面神经功能,且不会增加不良反应的发生。

家兔椎基底动脉供血不足动物模型的BAEP变化

目的 为了探讨家兔椎基底动脉缺血后的脑干听觉诱发电位 (brainstem auditory evoked poten-tials,BAEP)变化及其在临床工作中的意义。方法 通过结扎家兔单侧椎动脉从而造成脑干缺血 ,并连续记录结扎后一小时内的 BAEP的变化过程。结果 、 、 潜伏期逐渐延长 ,以 波延长最明显 , ～ 、 ～ 、 ～ 峰间期均明显延长 , 波、 波波幅改变无统计意义。结论 本实验表明在椎基底动脉供血不全时 BAEP有显著异常 ,可作为椎基底动脉梗死溶栓治疗后脑干功能变化的观察指标。

脑梗死患者非梗死侧正中神经体感诱发电位的研究

目的观察脑梗死患者非梗死侧正中神经体感诱发电位(SEP)的改变。方法对25例经头部MRI确诊的单侧颈内动脉脑梗死患者进行正中神经体感诱发电位检测并与正常对照组进行比较。结果脑梗死组与对照组比较,非梗死侧SEP的P15潜伏期延长(P<0.05)、N60潜伏期显著延长(P<0.001);25例脑梗死患者中8例患者非梗死侧SEP异常,异常率32%。结论SEP检测对发现脑梗死患者的微小病灶或亚临床病灶具有重要价值,其敏感性高于MRI。它是一种客观的、敏感的脑功能评定方法。