Economic growth and environmental "friendliness" are the dual missions of China's grand western development. In the past eight years,China has seen the gap between eastern and western regions still widen...Economic growth and environmental "friendliness" are the dual missions of China's grand western development. In the past eight years,China has seen the gap between eastern and western regions still widening while also taking on the arduous task of protecting nature,ecology and environment in the western region. How has western development fared in the past eight years? What difficulties and challenges are being encountered? The development of the western region poses the single greatest difficulty facing China's regional economic development,but how can we advance along a "sound and fast" development path? The establishment of economic zones in Chengdu and Chongqing,Guanzhong and North Bay has opened up new possibilities and expectations for western China's economic development.展开更多
Plant interphase cortical microtubules(cMTs)mediate anisotropic cell expansion in response to environmental and developmental cues.In Arabidopsis thaliana,KATANIN 1(KTN1),the p60 catalytic subunit of the conserved MT-...Plant interphase cortical microtubules(cMTs)mediate anisotropic cell expansion in response to environmental and developmental cues.In Arabidopsis thaliana,KATANIN 1(KTN1),the p60 catalytic subunit of the conserved MT-severing enzyme katanin,is essential for cMT ordering and anisotropic cell expansion.However,the regulation of KTN1-mediated cMT severing and ordering remains unclear.In this work,we report that the Arabidopsis IQ67 DOMAIN(IQD)family gene ABNORMAL SHOOT 6(ABS6)encodes a MT-associated protein.Overexpression of ABS6 leads to elongated cotyledons,directional pavement cell expansion,and highly ordered transverse cMT arrays.Genetic suppressor analysis revealed that ABS6-mediated cMT ordering is dependent on KTN1 and SHADE AVOIDANCE 4(SAV4).Live imaging of cMT dynamics showed that both ABS6 and SAV4 function as positive regulators of cMT severing.Furthermore,ABS6 directly interacts with KTN1 and SAV4 and promotes their recruitment to the cMTs.Finally,analysis of loss-of-function mutant combinations showed that ABS6,SAV4,and KTN1 work together to ensure the robust ethylene response in the apical hook of dark-grown seedlings.Together,our findings establish ABS6 and SAV4 as positive regulators of cMT severing and ordering,and highlight the role of cMT dynamics in fine-tuning differential growth in plants.展开更多
Non-coding regions are the major component of human genomes and the long non-coding RNA（IncRNA）is a class of pervasive genes located in noncoding regions（Morris and Mattick,2014）.IncRNAs play a wide range of regul...Non-coding regions are the major component of human genomes and the long non-coding RNA（IncRNA）is a class of pervasive genes located in noncoding regions（Morris and Mattick,2014）.IncRNAs play a wide range of regulatory roles in gene transcription,translation,epigenetic modification and protein function by interacting with different types of molecules including DNA,展开更多
文摘Economic growth and environmental "friendliness" are the dual missions of China's grand western development. In the past eight years,China has seen the gap between eastern and western regions still widening while also taking on the arduous task of protecting nature,ecology and environment in the western region. How has western development fared in the past eight years? What difficulties and challenges are being encountered? The development of the western region poses the single greatest difficulty facing China's regional economic development,but how can we advance along a "sound and fast" development path? The establishment of economic zones in Chengdu and Chongqing,Guanzhong and North Bay has opened up new possibilities and expectations for western China's economic development.
基金the Teaching and Research Core Facility at the College of Life Sciences,NWAFU for support in this worksupported by grants from the National Natural Science Foundation of China(31770205 and 31970186 to X.L.,31870268 to F.Y.)。
文摘Plant interphase cortical microtubules(cMTs)mediate anisotropic cell expansion in response to environmental and developmental cues.In Arabidopsis thaliana,KATANIN 1(KTN1),the p60 catalytic subunit of the conserved MT-severing enzyme katanin,is essential for cMT ordering and anisotropic cell expansion.However,the regulation of KTN1-mediated cMT severing and ordering remains unclear.In this work,we report that the Arabidopsis IQ67 DOMAIN(IQD)family gene ABNORMAL SHOOT 6(ABS6)encodes a MT-associated protein.Overexpression of ABS6 leads to elongated cotyledons,directional pavement cell expansion,and highly ordered transverse cMT arrays.Genetic suppressor analysis revealed that ABS6-mediated cMT ordering is dependent on KTN1 and SHADE AVOIDANCE 4(SAV4).Live imaging of cMT dynamics showed that both ABS6 and SAV4 function as positive regulators of cMT severing.Furthermore,ABS6 directly interacts with KTN1 and SAV4 and promotes their recruitment to the cMTs.Finally,analysis of loss-of-function mutant combinations showed that ABS6,SAV4,and KTN1 work together to ensure the robust ethylene response in the apical hook of dark-grown seedlings.Together,our findings establish ABS6 and SAV4 as positive regulators of cMT severing and ordering,and highlight the role of cMT dynamics in fine-tuning differential growth in plants.
基金supported by the National Natural Science Foundation of China(Nos.31270885 and 31471247)the open fund of Functional Oil Laboratory Associated by Oil Crops Research Institute,Chinese Academy of Agricultural Sciences and Infinitus (China) Company Ltd
文摘Non-coding regions are the major component of human genomes and the long non-coding RNA（IncRNA）is a class of pervasive genes located in noncoding regions（Morris and Mattick,2014）.IncRNAs play a wide range of regulatory roles in gene transcription,translation,epigenetic modification and protein function by interacting with different types of molecules including DNA,
