The Golden Ratio Theorem, deeply rooted in fractal mathematics, presents a pioneering perspective on deciphering complex systems. It draws a profound connection between the principles of interchangeability, self-simil...The Golden Ratio Theorem, deeply rooted in fractal mathematics, presents a pioneering perspective on deciphering complex systems. It draws a profound connection between the principles of interchangeability, self-similarity, and the mathematical elegance of the Golden Ratio. This research unravels a unique methodological paradigm, emphasizing the omnipresence of the Golden Ratio in shaping system dynamics. The novelty of this study stems from its detailed exposition of self-similarity and interchangeability, transforming them from mere abstract notions into actionable, concrete insights. By highlighting the fractal nature of the Golden Ratio, the implications of these revelations become far-reaching, heralding new avenues for both theoretical advancements and pragmatic applications across a spectrum of scientific disciplines.展开更多
This article discusses some views on the relationship between carrying out and applying standards and precision design and the teaching of a course on interchangeability and measurement techniques. It points out that ...This article discusses some views on the relationship between carrying out and applying standards and precision design and the teaching of a course on interchangeability and measurement techniques. It points out that while emphasizing precision design, we should not underrate the significance of interchangeability and standardization. Although there are presently many teaching models available for such courses, each course should be designed separately to preserve its systematic character and integrality. As well, the development of students' abilities in precision design and the application of standards should be strengthened in experimental lessons within each course.展开更多
This article discusses the roadbed splicing for hub interchanges.The article starts with a description of the characteristics of junction roadbed splicing.The application of splicing technology is explained using a su...This article discusses the roadbed splicing for hub interchanges.The article starts with a description of the characteristics of junction roadbed splicing.The application of splicing technology is explained using a subgrade splicing scheme of a project.Roadbed splicing involves stepwise excavation and preparative measures like surface cleaning and backfilling.This article serves to provide a valuable reference for road and bridge construction and improve the quality of China’s road and bridge projects,so as to achieve sustainable development of the road and bridge engineering industry.展开更多
This paper analyzes the structural design of an urban interchange ramp bridge from four aspects,which are the superstructure,pier structure,foundation structure,and deck structure design to summarize the structural de...This paper analyzes the structural design of an urban interchange ramp bridge from four aspects,which are the superstructure,pier structure,foundation structure,and deck structure design to summarize the structural design ideas of this urban interchange ramp bridge,which can be used as a reference for future construction of the same bridge.展开更多
The tropical Asian and Australasian floras have a close relationship,and is a vital distribution pattern of seed plants worldwide.As estimated,more than 81 families and 225 genera of seed plants distributed between tr...The tropical Asian and Australasian floras have a close relationship,and is a vital distribution pattern of seed plants worldwide.As estimated,more than 81 families and 225 genera of seed plants distributed between tropical Asia and Australasia.However,the evolutionary dynamics of two floras were still vague.Here,a total of 29 plant lineages,represented the main clades of seed plants and different habits,were selected to investigate the biotic interchange between tropical Asia and Australasia by integrated dated phylogenies,biogeography,and ancestral state reconstructions.Our statistics indicated that 68 migrations have occurred between tropical Asia and Australasia since the middle Eocene except terminal migrations,and the migration events from tropical Asia to Australasia is more than 2 times of the reverse.Only 12 migrations occurred before 15 Ma,whereas the remaining56 migrations occurred after 15 Ma.Maximal number of potential dispersal events(MDE) analysis also shows obvious asymmetry,with southward migration as the main feature,and indicates the climax of bi-directional migrations occurred after 15 Ma.We speculate that the formation of island chains after the Australian-Sundaland collision and climate changes have driven seed plant migrations since the middle Miocene.Furthermore,biotic dispersal and stable habitat may be crucial for floristic interchange between tropical Asia and Australasia.展开更多
Stabilization of the axisymmetric magnetic mirror relies on the pressure-weighted magnetic field curvature.We report a new experiment by configuring a magnetic cusp structure to stabilize m=1 interchange mode in the K...Stabilization of the axisymmetric magnetic mirror relies on the pressure-weighted magnetic field curvature.We report a new experiment by configuring a magnetic cusp structure to stabilize m=1 interchange mode in the KMAX tandem mirror.The cusp configuration is formed by reversing currents in the two side cell coils,and a stronger cusp can lead to a more stable plasma once the null point of the cusp is less than 35–40 cm away from the device axis.The density fluctuations measured by four axial Langmuir probes are mitigated by 70%–80%.The stabilization effect is consistent with the prediction of a theoretical calculation.展开更多
Based on the functions and characteristics of the interchange collector-distributor lanes,with Harbin as an example,it is proposed in this paper that the local characteristics and traffic flow characteristics should b...Based on the functions and characteristics of the interchange collector-distributor lanes,with Harbin as an example,it is proposed in this paper that the local characteristics and traffic flow characteristics should be considered in the design of the interchange collector-distributor lanes,which includes the analysis of function,location,and many other aspects,in hopes to provide reference for the design of collector-distributor lanes in other regions of our country.展开更多
In order to improve the safety of the exit of expressway interchanges,the main problems and influencing factors of interchange exits are analyzed according to the number of traffic accidents at expressway interchange ...In order to improve the safety of the exit of expressway interchanges,the main problems and influencing factors of interchange exits are analyzed according to the number of traffic accidents at expressway interchange exits in China.Some suggestions and countermeasures are then put forward from the aspect of safety technology for future reference.展开更多
With the rapid development of the socio-economy and the growing demand for transportation,highways have become an indispensable and important part of the modern transportation network.The design of highway routes and ...With the rapid development of the socio-economy and the growing demand for transportation,highways have become an indispensable and important part of the modern transportation network.The design of highway routes and interchanges is a key link in highway construction,which directly affects the efficiency,safety,and traffic smoothness of highways.Based on this,this article analyzes in detail the highway route design and the design of two common interchanges,in order to improve the highway route design and the quality and efficiency of highway construction.展开更多
Road traffic conditions can have an important impact on the economic development of various regions.Under the background of rapid social and economic development,more and more expressway construction projects are init...Road traffic conditions can have an important impact on the economic development of various regions.Under the background of rapid social and economic development,more and more expressway construction projects are initiated in various regions,including both new expressways and expansion of old expressways,and interchange design plays an important role.Scientific and reasonable interchange design can not only realize energy saving and low carbon footprint,but also be people-oriented and promote regional economic development.Therefore,this paper mainly analyzes the highway route and its interchange design strategy for reference.展开更多
The rapid advancement of urban transportation in modern China has driven urban economic developments.However,the progressively congested traffic conditions have affected the productivity and daily life of the people.T...The rapid advancement of urban transportation in modern China has driven urban economic developments.However,the progressively congested traffic conditions have affected the productivity and daily life of the people.To mitigate the congestion problem,necessary road designs should be implemented along the highways,for example highway interchanges.The application of highway interchanges in past cases have proven to effectively avoid traffic flow conflicts,reduce highway traffic congestion,and reduce traffic accidents,this is conducive to ensuring the safety and efficiency of the highway.In order to improve the safety and convenience of urban road traffic,this paper analyzes the strategy of using interchange ramp route designs for highway traffic.展开更多
China's road network consists of numerous older expressways experiencing high traffic volumes and severe congestion,necessitating urgent reconstruction and expansion efforts.This study discusses the reconstruction...China's road network consists of numerous older expressways experiencing high traffic volumes and severe congestion,necessitating urgent reconstruction and expansion efforts.This study discusses the reconstruction and expansion project of the Yinkun Expressway's Chongqing High-tech Zone to Rongchang District section,with a detailed exploration of the entire design process.Through a comprehensive analysis,the strengths and weaknesses of different plans are examined,so as to determine the optimal plan.The design chosen saves costs while effectively addressing traffic demands.Additionally,the study summarizes the valuable design insights gained from this interchange transformation,aiming to provide valuable reference for similar interchange projects in the future.展开更多
Biologic therapy, such as those that target tumor necrosis factor(TNF) signaling, has proven to be an efficacious method of treatment for patients with inflammatory bowel disease(IBD) with regards to symptom managemen...Biologic therapy, such as those that target tumor necrosis factor(TNF) signaling, has proven to be an efficacious method of treatment for patients with inflammatory bowel disease(IBD) with regards to symptom management and mucosal healing. However, the rising prevalence of IBD worldwide and the everincreasing burden of biologic pharmaceuticals in the health care industry is alarming for insurance companies, clinicians, and patients. The impending patent expiry and the relatively high costs of biologics, particularly anti-TNF agents, have paved the way for biosimilar development for IBD. The United States Food and Drug Administration defines a biosimilar as a biological product that is highly similar to its reference medicinal product, with no clinically meaningful differences in terms of safety, purity, and potency. The hope with biosimilars is that their entry into the market will be able to drive competition between pharmaceutical companies to reduce prices like that of the generic market, and that access to appropriate biologic treatments for IBD patients is increased in the long-term. Yet, there are challenging issues such as indication extrapolation and interchangeability that are still being debated in the field of IBD and must be addressed in future issued guidance. This review will discuss the issues and implications concerning the use of biosimilar therapy for IBD.展开更多
This manuscript developed an adjustability test system of gas appliances,and proposed determination methods of adjustability domain and technical approach of performance testing of gas appliance,in order to develop ex...This manuscript developed an adjustability test system of gas appliances,and proposed determination methods of adjustability domain and technical approach of performance testing of gas appliance,in order to develop experimental determination,quantify the product performance,design quality and combustion characteristics of gas appliances,and provide test foundation and platform for product design,performance test,quality assessment and technology upgrading for gas appliance industry aiming to multi-gas resources in China.The flexible range of gas appliances to different gases and the interchangeability domain of city gases were determined experimentally,together with the equation of combustion characteristics limit curves of gas appliances.The results showed that the second gas appliance has the biggest capability for the change of gas quality,which permits an 11.2% fluctuation in the Wobbe Index of gas;while the third gas appliance has the least capability for the change of gas quality,which only permits a 1.9% fluctuation in the Wobbe Index of gas.The paper also provides the common adjustability domain of the three gas appliances.展开更多
Biogas from renewable sources and natural gas(NG) are both high-efficient and good-quality gaseous fuels on account of their enrichment in methane. Due to the dissimilar physical properties of biogas and NG, biogas ca...Biogas from renewable sources and natural gas(NG) are both high-efficient and good-quality gaseous fuels on account of their enrichment in methane. Due to the dissimilar physical properties of biogas and NG, biogas cannot substitute NG directly without treatment and is usually used on site due to the high cost of the transportation and distribution via exclusive pipeline system. Consequently, the injection of biogas into existing NG infrastructure was proposed to address the deficiency. In this paper, the Wobbe index (WI) as well as the combustion potential (CP) were introduced for analyzing the interchangeability of an NGbiogas mixture, and a mathematical framework was put forward for modeling and simulating NG grid with a decentralized biogas injection. Results show that the maximum admissible amount of biogas in mixture was 10.5% by volume. A medium pressure network was used to interrogate the comprehensive effect of distributed biogas injection, which showed an impact on both gas quality and hydraulic regime across the grid.展开更多
文摘The Golden Ratio Theorem, deeply rooted in fractal mathematics, presents a pioneering perspective on deciphering complex systems. It draws a profound connection between the principles of interchangeability, self-similarity, and the mathematical elegance of the Golden Ratio. This research unravels a unique methodological paradigm, emphasizing the omnipresence of the Golden Ratio in shaping system dynamics. The novelty of this study stems from its detailed exposition of self-similarity and interchangeability, transforming them from mere abstract notions into actionable, concrete insights. By highlighting the fractal nature of the Golden Ratio, the implications of these revelations become far-reaching, heralding new avenues for both theoretical advancements and pragmatic applications across a spectrum of scientific disciplines.
文摘This article discusses some views on the relationship between carrying out and applying standards and precision design and the teaching of a course on interchangeability and measurement techniques. It points out that while emphasizing precision design, we should not underrate the significance of interchangeability and standardization. Although there are presently many teaching models available for such courses, each course should be designed separately to preserve its systematic character and integrality. As well, the development of students' abilities in precision design and the application of standards should be strengthened in experimental lessons within each course.
文摘This article discusses the roadbed splicing for hub interchanges.The article starts with a description of the characteristics of junction roadbed splicing.The application of splicing technology is explained using a subgrade splicing scheme of a project.Roadbed splicing involves stepwise excavation and preparative measures like surface cleaning and backfilling.This article serves to provide a valuable reference for road and bridge construction and improve the quality of China’s road and bridge projects,so as to achieve sustainable development of the road and bridge engineering industry.
文摘This paper analyzes the structural design of an urban interchange ramp bridge from four aspects,which are the superstructure,pier structure,foundation structure,and deck structure design to summarize the structural design ideas of this urban interchange ramp bridge,which can be used as a reference for future construction of the same bridge.
基金supported by the National Natural Science Foundation of China (31670212,3206005631300181)+1 种基金the National Natural Science Foundation of China-Yunnan Joint Fund Project (U1802242)Guangxi Key Laboratory Construction Project (19-185-7)。
文摘The tropical Asian and Australasian floras have a close relationship,and is a vital distribution pattern of seed plants worldwide.As estimated,more than 81 families and 225 genera of seed plants distributed between tropical Asia and Australasia.However,the evolutionary dynamics of two floras were still vague.Here,a total of 29 plant lineages,represented the main clades of seed plants and different habits,were selected to investigate the biotic interchange between tropical Asia and Australasia by integrated dated phylogenies,biogeography,and ancestral state reconstructions.Our statistics indicated that 68 migrations have occurred between tropical Asia and Australasia since the middle Eocene except terminal migrations,and the migration events from tropical Asia to Australasia is more than 2 times of the reverse.Only 12 migrations occurred before 15 Ma,whereas the remaining56 migrations occurred after 15 Ma.Maximal number of potential dispersal events(MDE) analysis also shows obvious asymmetry,with southward migration as the main feature,and indicates the climax of bi-directional migrations occurred after 15 Ma.We speculate that the formation of island chains after the Australian-Sundaland collision and climate changes have driven seed plant migrations since the middle Miocene.Furthermore,biotic dispersal and stable habitat may be crucial for floristic interchange between tropical Asia and Australasia.
基金the National Key R&D Program of China(No.2017YFE0301802)National Natural Science Foundation of China(No.12175226).
文摘Stabilization of the axisymmetric magnetic mirror relies on the pressure-weighted magnetic field curvature.We report a new experiment by configuring a magnetic cusp structure to stabilize m=1 interchange mode in the KMAX tandem mirror.The cusp configuration is formed by reversing currents in the two side cell coils,and a stronger cusp can lead to a more stable plasma once the null point of the cusp is less than 35–40 cm away from the device axis.The density fluctuations measured by four axial Langmuir probes are mitigated by 70%–80%.The stabilization effect is consistent with the prediction of a theoretical calculation.
文摘Based on the functions and characteristics of the interchange collector-distributor lanes,with Harbin as an example,it is proposed in this paper that the local characteristics and traffic flow characteristics should be considered in the design of the interchange collector-distributor lanes,which includes the analysis of function,location,and many other aspects,in hopes to provide reference for the design of collector-distributor lanes in other regions of our country.
文摘In order to improve the safety of the exit of expressway interchanges,the main problems and influencing factors of interchange exits are analyzed according to the number of traffic accidents at expressway interchange exits in China.Some suggestions and countermeasures are then put forward from the aspect of safety technology for future reference.
文摘With the rapid development of the socio-economy and the growing demand for transportation,highways have become an indispensable and important part of the modern transportation network.The design of highway routes and interchanges is a key link in highway construction,which directly affects the efficiency,safety,and traffic smoothness of highways.Based on this,this article analyzes in detail the highway route design and the design of two common interchanges,in order to improve the highway route design and the quality and efficiency of highway construction.
文摘Road traffic conditions can have an important impact on the economic development of various regions.Under the background of rapid social and economic development,more and more expressway construction projects are initiated in various regions,including both new expressways and expansion of old expressways,and interchange design plays an important role.Scientific and reasonable interchange design can not only realize energy saving and low carbon footprint,but also be people-oriented and promote regional economic development.Therefore,this paper mainly analyzes the highway route and its interchange design strategy for reference.
文摘The rapid advancement of urban transportation in modern China has driven urban economic developments.However,the progressively congested traffic conditions have affected the productivity and daily life of the people.To mitigate the congestion problem,necessary road designs should be implemented along the highways,for example highway interchanges.The application of highway interchanges in past cases have proven to effectively avoid traffic flow conflicts,reduce highway traffic congestion,and reduce traffic accidents,this is conducive to ensuring the safety and efficiency of the highway.In order to improve the safety and convenience of urban road traffic,this paper analyzes the strategy of using interchange ramp route designs for highway traffic.
文摘China's road network consists of numerous older expressways experiencing high traffic volumes and severe congestion,necessitating urgent reconstruction and expansion efforts.This study discusses the reconstruction and expansion project of the Yinkun Expressway's Chongqing High-tech Zone to Rongchang District section,with a detailed exploration of the entire design process.Through a comprehensive analysis,the strengths and weaknesses of different plans are examined,so as to determine the optimal plan.The design chosen saves costs while effectively addressing traffic demands.Additionally,the study summarizes the valuable design insights gained from this interchange transformation,aiming to provide valuable reference for similar interchange projects in the future.
文摘Biologic therapy, such as those that target tumor necrosis factor(TNF) signaling, has proven to be an efficacious method of treatment for patients with inflammatory bowel disease(IBD) with regards to symptom management and mucosal healing. However, the rising prevalence of IBD worldwide and the everincreasing burden of biologic pharmaceuticals in the health care industry is alarming for insurance companies, clinicians, and patients. The impending patent expiry and the relatively high costs of biologics, particularly anti-TNF agents, have paved the way for biosimilar development for IBD. The United States Food and Drug Administration defines a biosimilar as a biological product that is highly similar to its reference medicinal product, with no clinically meaningful differences in terms of safety, purity, and potency. The hope with biosimilars is that their entry into the market will be able to drive competition between pharmaceutical companies to reduce prices like that of the generic market, and that access to appropriate biologic treatments for IBD patients is increased in the long-term. Yet, there are challenging issues such as indication extrapolation and interchangeability that are still being debated in the field of IBD and must be addressed in future issued guidance. This review will discuss the issues and implications concerning the use of biosimilar therapy for IBD.
基金Sponsored by the National Key Technologies R&D Program of China during the 11th Five-Year Plan Period(Grant No.2006BAJ03B02)
文摘This manuscript developed an adjustability test system of gas appliances,and proposed determination methods of adjustability domain and technical approach of performance testing of gas appliance,in order to develop experimental determination,quantify the product performance,design quality and combustion characteristics of gas appliances,and provide test foundation and platform for product design,performance test,quality assessment and technology upgrading for gas appliance industry aiming to multi-gas resources in China.The flexible range of gas appliances to different gases and the interchangeability domain of city gases were determined experimentally,together with the equation of combustion characteristics limit curves of gas appliances.The results showed that the second gas appliance has the biggest capability for the change of gas quality,which permits an 11.2% fluctuation in the Wobbe Index of gas;while the third gas appliance has the least capability for the change of gas quality,which only permits a 1.9% fluctuation in the Wobbe Index of gas.The paper also provides the common adjustability domain of the three gas appliances.
基金Funded by China 12th Five-year Plan Key R&D Program(2013BAJ11B05)
文摘Biogas from renewable sources and natural gas(NG) are both high-efficient and good-quality gaseous fuels on account of their enrichment in methane. Due to the dissimilar physical properties of biogas and NG, biogas cannot substitute NG directly without treatment and is usually used on site due to the high cost of the transportation and distribution via exclusive pipeline system. Consequently, the injection of biogas into existing NG infrastructure was proposed to address the deficiency. In this paper, the Wobbe index (WI) as well as the combustion potential (CP) were introduced for analyzing the interchangeability of an NGbiogas mixture, and a mathematical framework was put forward for modeling and simulating NG grid with a decentralized biogas injection. Results show that the maximum admissible amount of biogas in mixture was 10.5% by volume. A medium pressure network was used to interrogate the comprehensive effect of distributed biogas injection, which showed an impact on both gas quality and hydraulic regime across the grid.