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Treatment of Protrusion of the Lumbar Intervertebral Disc by TCM Massage 被引量:1
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作者 龙亚军 叶环 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2002年第2期126-127,共2页
  Protrusion of the lumbar intervertebral disc is a common disorder frequently encountered in clinic. With TCM massage and the maneuver of manual reduction, we have treated 82 cases of protrusion of the lumbar inter...   Protrusion of the lumbar intervertebral disc is a common disorder frequently encountered in clinic. With TCM massage and the maneuver of manual reduction, we have treated 82 cases of protrusion of the lumbar intervertebral disc, with satisfactory therapeutic results reported in the following.…… 展开更多
关键词 Lumbar Vertebrae FEMALE Humans intervertebral disk Displacement MALE MASSAGE TRACTION
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Treatment of Protrusion of Lumbar Intervertebral Disc by Pulling and Turning Manipulations 被引量:1
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作者 刘杰 张生权 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第3期195-197,共3页
The authors treated 62 cases of protrusion oflumbar intervertebral disc by pulling and turningmanipulations from February 1993 to February 1998.Another 50 cases were treated by traction as controls.Statistical data sh... The authors treated 62 cases of protrusion oflumbar intervertebral disc by pulling and turningmanipulations from February 1993 to February 1998.Another 50 cases were treated by traction as controls.Statistical data showed that pulling and turningmanipulations had much better therapeuticeffectiveness than traction(P<0.05). 展开更多
关键词 Lumbar Vertebrae Acupuncture Points ADULT Female Humans intervertebral disk Displacement Male MASSAGE Middle Aged
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Treatment of Protrusion of the Lumbar Intervertebral Disc by Massotherapy
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作者 程斌 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第2期110-110,共1页
Clinically, there is a higher incidence of protrusion of the lumbar intervertebral disc. It can cause a terrible pain. The author has treated 66 cases by massotherapy, who were confirmatively diagnosed as having protr... Clinically, there is a higher incidence of protrusion of the lumbar intervertebral disc. It can cause a terrible pain. The author has treated 66 cases by massotherapy, who were confirmatively diagnosed as having protrusion of the lumbar intervertebral disc by X-ray film and computer-aided tomography, with satisfactory results as reported in the following.Clinical DataAmong the 66 cases in this series, 49 were male and 17 female, ranging in age from 26 to 59 years, averaging 36.2 years. All the patients had got lumbago and unilateral ischialgia, with the left side affected in 37 cases and the right side in 29 cases. The leg pain radiating to lateral malleolus was found in 28 cases, to dorsum of the foot in 24 cases, and to the toes in 14 cases. Intermittent claudication was present in 22 cases, numbness of the affected foot in 16 cases, pain exacerbated when coughing in 35 cases, scoliosis in 21 cases, and positive Lasegue's sign in 48 cases. 展开更多
关键词 Lumbar Vertebrae MASSAGE ADULT FEMALE Humans intervertebral disk Displacement MALE Middle Aged
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Treatment of Protrusion of the Lumbar Intervertebral Disc by Intravertebral Blocking and Massotherapy——A Report of 62 Cases
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作者 张大炯 周永生 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第2期138-140,共3页
Protrusion of the lumbar intervertebral disc is adisease commonly encountered in orthopedics andtraumatology clinic.At present removal of thenucleus pulposus to relieve the compression on thenerve root is usually adop... Protrusion of the lumbar intervertebral disc is adisease commonly encountered in orthopedics andtraumatology clinic.At present removal of thenucleus pulposus to relieve the compression on thenerve root is usually adopted in the treatment of thedisease.From April,1990 to October,1997,theauthor treated 62 cases of protrusion of the lumbarintervertebral disc by massotherapy afterintravertebral blocking,with satisfactory 展开更多
关键词 MASSAGE ADULT FEMALE Follow-Up Studies Humans intervertebral disk Displacement MALE Middle Aged
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Effect of siRNA interference on nerve growth factor in intervertebral disc inflammation rats
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作者 Ming-Lei Lang Ai-Lin Qin +1 位作者 Jian-Min Li Peng Fu 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2014年第9期739-743,共5页
Objective:To investigate the inhibition effect of siRNA interference on NGF induced by inflammatory factor IL-6,and JUL—1 so as to provide novel targets for clinical treatment of discogenic low back pain.Methods:The ... Objective:To investigate the inhibition effect of siRNA interference on NGF induced by inflammatory factor IL-6,and JUL—1 so as to provide novel targets for clinical treatment of discogenic low back pain.Methods:The intervertebral disc nucleus and annulus fibrosus cells of rats were separated-The cells were co-cultured with different concentrations(10 nmol/L,20nmol/L,50 nmol/L,100 nmol/L)of IL-6 and IL-1β.The NGF-siRNA was leaded into the cocultured cells with its import ability assessed by flow cytometry instrument tests,hefore and after which the NCF mRNA expression was detected by real-time Q-PCR and the NGF content was detected by ELISA.Results:Flow cytometry instrument test results showed that the NGFsiRNA cell conversion rate was 99.8%.Real-time Q-PCR detection results showed that compared with negative control group,the NGF mRNA expression of co-cultured cells treated by 10 nmol/L,20 nmol/L,50 nmol/L,100 nmol/L IL-6 and IL-1βwere respectively raised 3.4,3.7,4.7,3.7 times which were all significantly down-regulated after the import of NGF-siRNA.EILSA detection results showed that compared with negative control group,the NGF content of cocultured medium treated by 10 nmol/L,20 nmol/L,50 nmol/L,100 nmol/L I-L6 and IL-1βwere respectively raised 2.9,3.3,4.5,7.4 times which were all significantly decreased after the import of NGF-siRNA.Conclusions:These molecular biological results suggest that inflammatory factor IL-6 and IL-1βcould stimulate NCF on intervertebral disc cells in vitro culture model and its efficiency is concentration dependent,while siRNA interference can inhibit the stimulation effect of IL-6 and IL-1βon intervertebral disc cell,which provides a new targets for the clinical treatment of discogenic low back pain. 展开更多
关键词 RNA Small interfering Nerve growth factor Low back pain intervertebral disk displacement
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Fifty-six Cases of Protrusion of Lumbar Intervertebral Disc Treated by Penetration and Oral Administration of Chinese Decoction Plus Traction
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作者 钟琪 周永生 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第4期273-276,共4页
Fifty-six cases of the protrusion of the lumbar intervertebral disc in the treatment group were treated by drug-penetration and oral administration of traditional Chinese decoction plus traction, and the other 35 case... Fifty-six cases of the protrusion of the lumbar intervertebral disc in the treatment group were treated by drug-penetration and oral administration of traditional Chinese decoction plus traction, and the other 35 cases in the control group by oral administration of Chinese decoction and traction. The results showed that the cure rate in the treatment group was 83.9%, and that in the control group was 57.1%, with a statistically significant difference between the two groups (P<0.01), indicating that the former is a more effective therapy for protrusion of the lumbar intervertebral disc. 展开更多
关键词 Lumbar Vertebrae ADULT Aged Drugs Chinese Herbal Female Humans intervertebral disk Displacement IONTOPHORESIS Male Middle Aged TRACTION
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TCM Treatment for 50 Cases of Acute Protrusion of the Lumbar Intervertebral Disc
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作者 梁述元 周永生 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2001年第4期265-266,共2页
From January 1998 to August 2000, the author has treated 50 cases of acute protrusion of the lumbar intervertebral disc by Chinese herbs, massotherapy, and functional exercise with satisfactory therapeutic results rep... From January 1998 to August 2000, the author has treated 50 cases of acute protrusion of the lumbar intervertebral disc by Chinese herbs, massotherapy, and functional exercise with satisfactory therapeutic results reported in the following. 展开更多
关键词 ADULT Combined Modality Therapy Drugs Chinese Herbal Exercise Therapy FEMALE Humans intervertebral disk Displacement MALE MASSAGE Middle Aged
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Protrusion of Lumbar Intervertebral Disc Treated by Ultra Short Wave and the Point Injection in 40 Cases
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作者 张彩芳 陈正秋 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2003年第1期43-44,共2页
Since 1996,the author has treated 40 cases of protrusion of lumbar intervertebral disc with ultra short wave and the point injection,and obtained good therapeutic effects.This is reported as follows.
关键词 Acupuncture Points Lumbar Vertebrae Short-Wave Therapy ADULT Combined Modality Therapy FEMALE Humans INJECTIONS intervertebral disk Displacement MALE Middle Aged THIAMINE Vitamin B 12
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硫酸溶液中SUS304不锈钢旋转圆盘电极电流振荡现象的研究
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作者 罗韦因 小仓兴太郎 中山雅晴 《中国腐蚀与防护学报》 CAS CSCD 1998年第2期155-160,共6页
硫酸溶液中SUS304不锈钢旋转圆盘电极在正向电位扫描时产生电流振荡现象。振荡电流所对应的电位范围以及电流振荡幅度与溶液温度,硫酸浓度、电位扫描速度以及电极旋转速度存在着对应关系.在电位线性扫描条件下,溶液温度高于35.0℃、硫... 硫酸溶液中SUS304不锈钢旋转圆盘电极在正向电位扫描时产生电流振荡现象。振荡电流所对应的电位范围以及电流振荡幅度与溶液温度,硫酸浓度、电位扫描速度以及电极旋转速度存在着对应关系.在电位线性扫描条件下,溶液温度高于35.0℃、硫酸浓度大于2.5mol·L^(-1)以及电极旋转速度不大干1000rpm时,可观测到电流振荡现象。电流振荡现象的产生与电极溶解过程、Cr_2O_7^(2-)的生成。O_2的离析及MCr_2O_7盐膜的生成和裂解有着密切的关系。 展开更多
关键词 电流振荡 不锈钢 旋转圆盘电极 硫酸溶液
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益肾强骨汤联合一指禅推拿治疗急性期腰椎间盘突出症疗效观察 被引量:2
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作者 王丹丹 李宵 王泰然 《西部中医药》 2024年第1期158-160,共3页
目的:探讨益肾强骨汤联合一指禅推拿治疗急性期腰椎间盘突出症的临床疗效。方法:将120例急性期腰椎间盘突出症患者随机分为对照组和观察组各60例。对照组采用塞来昔布口服联合一指禅推拿治疗,观察组采用益肾强骨汤联合一指禅推拿治疗。... 目的:探讨益肾强骨汤联合一指禅推拿治疗急性期腰椎间盘突出症的临床疗效。方法:将120例急性期腰椎间盘突出症患者随机分为对照组和观察组各60例。对照组采用塞来昔布口服联合一指禅推拿治疗,观察组采用益肾强骨汤联合一指禅推拿治疗。观察两组患者临床疗效、日本骨科协会评分(Japanese orthopaedic association scores JOA)及血清炎症因子[白细胞介素1β(Interleukin-1β,IL-1β)、白细胞介素6(Interleukin-6,IL-6)、肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)]水平。结果:观察组总有效率为93.33%(56/60),高于对照组的83.33%(50/60)(P<0.05);治疗后观察组JOA评分高于对照组(P<0.05);治疗后两组患者IL-1β、IL-6、TNF-α水平均降低,观察组降低更明显(P<0.05)。结论:益肾强骨汤联合一指禅推拿可降低急性期腰椎间盘突出症患者血清IL-1β、IL-6、TNF-α水平,改善患者腰椎功能。 展开更多
关键词 椎间盘移位 血清炎症因子 JOA评分 益肾强骨汤 一指禅推拿
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显微镜和椎间孔镜下腰椎间盘切除术治疗腰椎间盘突出症的临床疗效
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作者 陈涛 童新宙 +3 位作者 郑阳 康忠山 康鹏程 陈良龙 《医学临床研究》 CAS 2024年第1期22-24,28,共4页
【目的】探讨显微镜下椎间盘切除术(MSLD)和经皮椎间孔镜下腰椎间盘切除术(PELD)治疗腰椎间盘突出症的临床疗效。【方法】回顾性分析2013年12月至2022年5月在娄底市中心医院行微创手术治疗的486例腰椎间盘突出症患者的临床资料,其中行M... 【目的】探讨显微镜下椎间盘切除术(MSLD)和经皮椎间孔镜下腰椎间盘切除术(PELD)治疗腰椎间盘突出症的临床疗效。【方法】回顾性分析2013年12月至2022年5月在娄底市中心医院行微创手术治疗的486例腰椎间盘突出症患者的临床资料,其中行MSLD治疗的患者192例(MSLD组)和行PELD治疗的患者294例(PEID组),比较两组患者术前,术后1周、3个月、6个月、12个月以及末次随访(术后24个月)的疼痛视觉模拟评分(VAS)、徒手肌力检查(MMT)评分及相关并发症发生率。【结果】两组患者术后各个时间点VAS均显著低于术前(P<0.05);但两组治疗前后各个时间点VAS比较,差异无统计学意义(P>0.05)。两组患者术后各个时间点MMT评分均显著高于术前(P<0.05);但两组治疗前后各个时间点MMT评分比较,差异无统计学意义(P>0.05)。MSLD组总并发症发生率为2.60%(5/192),显著低于PELD组的8.50%(25/294),差异有统计学意义(P<0.05)。【结论】MSLD和PELD手术均可有效减轻腰椎间盘突出症患者疼痛,但PELD在局麻下操作,术中可检查患者的下肢肌力、疼痛与麻木的反馈,其警示作用可减少神经损伤,降低并发症发生率。 展开更多
关键词 椎间盘移位/外科学 腰椎/外科学 椎间盘切除术 治疗结果
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电针夹脊穴对压力诱导退变椎间盘纤维环的影响
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作者 汪敏 邹璟 +5 位作者 周婷 程佩 边清灵 刘子慧 杨澳 黄国付 《中国中西医结合影像学杂志》 2024年第5期526-531,共6页
目的:探讨电针夹脊穴对压力诱导退变椎间盘纤维环形态结构的影响。方法:随机将20只成年雄性新西兰大白兔分为正常组、假手术组、模型组和电针组,每组5只。通过外置轴向加压器械诱导腰椎间盘退变(IVDD)模型,轴向加压28 d后使用MRI评估造... 目的:探讨电针夹脊穴对压力诱导退变椎间盘纤维环形态结构的影响。方法:随机将20只成年雄性新西兰大白兔分为正常组、假手术组、模型组和电针组,每组5只。通过外置轴向加压器械诱导腰椎间盘退变(IVDD)模型,轴向加压28 d后使用MRI评估造模效果。电针组在造模成功后第1天开始电针双侧夹脊穴治疗28 d。电针干预结束后观察记录4组实验兔的精神状态、饮食、活动和对外界的刺激情况并评分;使用MRI观察各组椎间盘的信号强度并行Pfirrmann分级评估;采用HE染色和透射电镜比较4组椎间盘纤维环组织形态及亚细胞结构;采用免疫组化染色检测各组实验兔椎间盘纤维环细胞中的血小板反应蛋白解整合素金属肽酶-5(ADAMTS-5)抗体阳性表达。结果:与假手术组比较,模型组实验兔的综合反应评分降低(P<0.01),椎间盘信号消失,Pfirrmann分级明显升高,纤维环组织结构破坏,细胞排列紊乱,纤维软骨细胞增多,胶原纤维组织内的纤维细小,排列紊乱,纤维环细胞中ADAMTS-5抗体阳性表达明显增多(P<0.01);与模型组比较,电针组实验兔的综合反应评分升高(P<0.01),椎间盘信号改善,Pfirrmann分级降低,纤维环结构和胶原纤维形态改善,纤维环细胞中ADAMTS-5抗体阳性表达明显降低(P<0.01)。结论:轴向加压刺激能明显破坏纤维环细胞形态及组织结构,并引起纤维环细胞外基质的降解,而电针能在一定程度上改善退变的纤维环,进而延缓IVDD。 展开更多
关键词 腰椎间盘退变 电针 纤维环 磁共振成像
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Exploration of the Clinical Rule of Acupuncturemoxibustion Treatment for Lumbar Intervertebral Disk Herniation 被引量:8
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作者 黄琴峰 吴耀持 汪司右 《Journal of Acupuncture and Tuina Science》 2009年第3期177-180,共4页
Objective: To review year 1956-2007 literature on acupuncture and moxibustion and explore the regularity of point selection and methods for acupuncture-moxibustion treatment of lumbar intervertebral disk herniation. ... Objective: To review year 1956-2007 literature on acupuncture and moxibustion and explore the regularity of point selection and methods for acupuncture-moxibustion treatment of lumbar intervertebral disk herniation. Methods: A comprehensive analysis was made by a method of metrological analysis according to the data from "China modem acupuncture-moxibustion information databank". Results: Points Huantiao (GB 30), Weizhong (BL 40), Yanglingquan (GB 34), and Jiaji (Ex-B 2) were most frequently used. Acupuncture was the most frequently used therapy and electroacupuncture, the next one. Conclusion: Electroacupuncture is a common and effective way to treat lumbar intervertebral disk herniation. Points Huantiao (GB 30), Weizhong (BL 40), Yanglingquan (GB 34), and Jiaji (Ex-B 2) can be used as a basic prescription for acupuncture-moxibustion treatment of lumbar intervertebral disk herniation. Other acupoints are selected according to the syndrome. 展开更多
关键词 intervertebral disk Displacement Low Back Pain Acupuncture-moxibustion Therapy LITERATURE
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Treatment of Lumbar Intervertebral Disk Herniation with Electric Acupuncture 被引量:2
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作者 张必萌 吴耀持 邵萍 《Journal of Acupuncture and Tuina Science》 2007年第4期216-220,共5页
Objective: To make objective evaluation on treatment of lumbar intervertebral disc herniation with electric acupuncture. Method: All 200 cases were randomly allocated into an observation group (100 cases) and a co... Objective: To make objective evaluation on treatment of lumbar intervertebral disc herniation with electric acupuncture. Method: All 200 cases were randomly allocated into an observation group (100 cases) and a control group (100 cases). Cases in the observation group were treated with electric acupuncture. Cases in the control group were treated with oral administration of Mobic. Result: The total effective rate in the observation group was 86.5%, and the total effective rate of the control group was 75.0%. There was a significant difference between the two groups (P〈0.01). Conclusion: Electric acupuncture is a safe and remarkably effective way for lumbar intervertebral disc herniation. 展开更多
关键词 intervertebral disk Displacement Acupuncture-Moxibustion Therapy ELECTROACUPUNCTURE
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Treatment of 52 Cases of Lumbar Intervertebral Disk Herniation by Acupuncture plus Herbal Medicine 被引量:2
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作者 谢正红 李素荷 黄国琪 《Journal of Acupuncture and Tuina Science》 2009年第6期368-370,共3页
Lumbar intervertebral disk herniation is a commonly and frequently encountered disease in the orthopedic department, manifested by a series of symptoms such as low back pain, numbness and pain in one or two lower limb... Lumbar intervertebral disk herniation is a commonly and frequently encountered disease in the orthopedic department, manifested by a series of symptoms such as low back pain, numbness and pain in one or two lower limbs, due to compression to the lumbosacral nerves by protrusion of the pulpiform nucleus after rupture of the fibrous rings. The author has treated 52 cases of this disease by acupuncture plus herbal medicine. Now, the report is given as follows. 展开更多
关键词 intervertebral disk Displacement Low Back Pain Acupuncture-moxibustion Therapy Acupuncture Medication Combined
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经皮脊柱内镜经椎板入路手术治疗腰椎不稳伴腰椎间盘突出症患者的临床疗效
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作者 张冰 马航 《医学临床研究》 CAS 2024年第11期1726-1728,1732,共4页
【目的】探讨经皮脊柱内镜经椎板入路手术治疗腰椎不稳伴腰椎间盘突出症患者的临床疗效。【方法】回顾性分析2019年5月至2022年5月在本院行经皮脊柱内镜经椎板入路手术的164例腰椎不稳伴腰椎间盘突出症患者(A组),另选取同期在本院行常... 【目的】探讨经皮脊柱内镜经椎板入路手术治疗腰椎不稳伴腰椎间盘突出症患者的临床疗效。【方法】回顾性分析2019年5月至2022年5月在本院行经皮脊柱内镜经椎板入路手术的164例腰椎不稳伴腰椎间盘突出症患者(A组),另选取同期在本院行常规开放手术的97例患者(B组)。比较两组患者术前及术后的腰腿疼痛情况[视觉模拟评分法(visual analogue scale,VAS)]、腰椎功能障碍程度[Oswestry功能障碍指数(ODI)]及治疗效果、并发症发生情况。【结果】两组术前腰腿痛VAS评分及ODI评分比较,差异无统计学意义(P>0.05)。两组术后1 d、术后1个月、术后3个月的腰腿痛VAS评分及ODI评分,术后12个月ODI评分比较,差异有统计学意义(P<0.05),两组术后12个月腰腿痛VAS评分比较,差异均无统计学意义(P>0.05);A组术后1 d、术后1个月、术后3个月的腰腿痛VAS评分及ODI评分,术后12个月的ODI评分均低于B组。术后12个月,A组疗效优于B组(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。【结论】相对于常规开放手术,经皮脊柱内镜经椎板入路治疗腰椎不稳伴腰椎间盘突出症患者,临床疗效显著,可改善患者疼痛程度和腰椎康复效果,且安全性较好。 展开更多
关键词 腰椎/外科学 椎间盘移位/并发症 椎间盘移位/外科学 椎间盘切除术 经皮 治疗结果
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脊柱内镜辅助下的经椎间孔腰椎椎体间融合术治疗腰椎间盘突出症肥胖患者的临床效果
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作者 张冰 马航 《医学临床研究》 CAS 2024年第9期1331-1334,1338,共5页
【目的】探讨脊柱内镜辅助下的经椎间孔腰椎椎体间融合术(TLIF)治疗腰椎间盘突出症(LDH)肥胖患者的临床效果。【方法】选择2020年2月至2022年5月本院收治的93例LDH肥胖患者,按照手术方法不同分为观察组(接受脊柱内镜辅助下的TLIF治疗,n=... 【目的】探讨脊柱内镜辅助下的经椎间孔腰椎椎体间融合术(TLIF)治疗腰椎间盘突出症(LDH)肥胖患者的临床效果。【方法】选择2020年2月至2022年5月本院收治的93例LDH肥胖患者,按照手术方法不同分为观察组(接受脊柱内镜辅助下的TLIF治疗,n=47)和对照组(接受传统后路开放手术治疗,n=46)。比较两组手术相关指标、视觉模拟评分法(visual analogue scale,VAS)评分、腰椎功能[日本骨科协会(Japanese Orthopaedic Association,JOA)评分与Oswestry功能障碍指数(Oswestry disability index,ODI)评分]、影像学参数、塌陷率、融合率及并发症发生率。【结果】观察组手术时间长于对照组(P<0.05),总住院时间、术后首次下床时间短于对照组(P<0.05),术中出血量少于对照组(P<0.05)。两组术前、术后1 d、术后12个月的ODI评分、下肢VAS评分、JOA评分、腰部VAS评分比较,差异均无统计学意义(P>0.05)。术后12个月,两组顶椎中心偏移距离、腰椎冠状位Cobb角均低于术前,腰椎矢状位Cobb角均高于术前,差异均有统计学意义(P<0.05),且观察组顶椎中心偏移距离、腰椎冠状位Cobb角、腰椎矢状位Cobb角恢复情况优于对照组(P<0.05)。观察组塌陷率明显低于对照组(P<0.05),融合率高于对照组(P<0.05)。两组并发症总发生率比较,差异无统计学意义(P>0.05)。【结论】与传统后路开放手术相比,脊柱内镜辅助下的TLIF治疗LDH肥胖患者效果更好,影像学参数改善更佳,患者恢复更快,融合器塌陷风险更低,且融合率更高。 展开更多
关键词 椎间盘移位/外科学 腰椎/外科学 脊柱融合术/方法 内窥镜检查
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Association Between VDR FokI Polymorphism and Intervertebral Disk Degeneration
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作者 Jian Zhao Mingyuan Yang +2 位作者 Jie Shao Yushu Bai Ming Li 《Genomics, Proteomics & Bioinformatics》 SCIE CAS CSCD 2015年第6期371-376,共6页
Intervertebral disk degeneration (IDD) is strongly associated with genetic predisposition and environmental susceptibility. Several studies been conducted to investigate the potential asso- ciation between IDD and F... Intervertebral disk degeneration (IDD) is strongly associated with genetic predisposition and environmental susceptibility. Several studies been conducted to investigate the potential asso- ciation between IDD and FokI polymorphism located in the gene encoding the vitamin D receptor (VDR), and inconsistent conclusions had been reached among different ethnic populations. In order to assess the association between the FokI polymorphism and the risk of IDD, we performed a comprehensive and systematic meta-analysis. Candidate articles were retrieved from PubMed, EMBASE, China National Knowledge Infrastructure (CNKI), and China Biology Medical (CBM) with strict inclusion criteria in January 2015. Among the 54 articles that were retrieved, only eight studies met the inclusion criteria. The pooled data analysis based on allele contrast, homozy- gore, heterozygote, dominant, and recessive models revealed no significant correlation between the FokI polymorphism and the risk of IDD. However, when stratified by ethnicity, significant associ- ations were detected for Hispanics based on allele contrast (OR = 1.395, 95% CI = 1.059-1.836, P = 0.018), homozygote (OR = 1.849, 95% CI = 1.001-3.416, P = 0.049), heterozygote (OR = 1.254, 95% CI = 1.049-1.498, P = 0.013), and dominant (OR = 1.742, 95% CI = 1.174-2.583, P = 0.006) models, and for Asians using the dominant model (OR = 1.293, 95% CI = 1.025-1.632, P --- 0.030), whereas there is no significant association detected for Caucasians. In conclusion, FokI polymorpbism is not generally associated with IDD, but there is increased risk for IDD in Hispanics and Asians carrying FokI allele T. 展开更多
关键词 FokI polymorphism rs2228570 Vitamin D receptor disk degeneration intervertebral disk disease
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椎间盘源性腰痛射频热凝+臭氧减压辅助腰背肌 锻炼的疗效探讨
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作者 吴振华 张兵 《系统医学》 2024年第20期93-96,共4页
目的研究椎间盘源性腰痛射频热凝+臭氧减压辅助腰背肌锻炼的疗效。方法非随机选取深圳精诚医疗集团如皋医院于2021年1月—2024年1月收治的94例椎间盘源性腰痛患者作为研究对象,按治疗方法不同进行分组,每组47例,对照组应用射频热凝联合... 目的研究椎间盘源性腰痛射频热凝+臭氧减压辅助腰背肌锻炼的疗效。方法非随机选取深圳精诚医疗集团如皋医院于2021年1月—2024年1月收治的94例椎间盘源性腰痛患者作为研究对象,按治疗方法不同进行分组,每组47例,对照组应用射频热凝联合臭氧减压辅助物理康复牵引方案治疗,观察组应用射频热凝联合臭氧减压辅助腰背肌锻炼方案治疗。对比两组临床疗效、疼痛程度和腰椎功能指标水平。结果观察组临床总有效率为97.87%(46/47),高于对照组的85.11%(40/47),差异有统计学意义(χ^(2)=4.919,P<0.05);观察组Oswestry功能障碍指数、疼痛评分均低于对照组,日本骨科协会评分高于对照组,差异有统计学意义(P均<0.05)。结论于椎间盘源性腰痛患者的临床治疗中,射频热凝、臭氧减压辅助腰背肌锻炼联合应用展现出显著的临床效果。 展开更多
关键词 射频热凝 臭氧 椎间盘源性腰痛 腰椎功能
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Treatment of 120 Cases of Lumber Intervertebral Disk Displacement by Electroacupuncture plus Movable Cupping and Traction
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作者 LU Guo-ping LONG Jia-jun WU Xue-fei 《Journal of Acupuncture and Tuina Science》 2003年第2期50-51,共2页
Ashi points, movable cupping and traction were employed to treat 120 cases of prolapase of lumber intervertebral disk, and the total effective rate was 95.6%. Key Words Lumber Vertebrae - Electroacupuncture - Cupping... Ashi points, movable cupping and traction were employed to treat 120 cases of prolapase of lumber intervertebral disk, and the total effective rate was 95.6%. Key Words Lumber Vertebrae - Electroacupuncture - Cupping Therapy - Acupuncture-moxibustion - Traction - Intervertebral Disk Dislacement Author: Lü Guo-ping (1958-), female, attending physicianTranslator: WU Xue-fei 展开更多
关键词 Lumber Vertebrae ELECTROACUPUNCTURE Cupping Therapy ACUPUNCTURE-MOXIBUSTION TRACTION intervertebral disk Dislacement
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