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Value of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment: A prospective evaluation 被引量:8
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作者 Hok-Kwok Choi Wai-Lun Law +1 位作者 Judy Wai-Chu Ho Kin-Wah Chu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第24期3742-3745,共4页
AIM: Gastrografin is a hyperosmolar water-soluble contrast medium. Besides its predictive value for the need for operative treatment, a potential therapeutic role of this agent in adhesive small bowel obstruction has ... AIM: Gastrografin is a hyperosmolar water-soluble contrast medium. Besides its predictive value for the need for operative treatment, a potential therapeutic role of this agent in adhesive small bowel obstruction has been suggested. This study aimed at evaluating the effectiveness of gastrografin in adhesive small bowel obstruction when conservative treatment failed. METHODS: Patients with adhesive small bowel obstruction were given trial conservative treatment unless there was fear of bowel strangulation. Those responded in the initial 48 h had conservative treatment continued. Patients who showed no improvement in the initial 48 h were given 100 mL of gastrografin through nasogastric tube followed by serial abdominal radiographs. Patients with the contrast appeared in large bowel within 24 h were regarded as having partial obstruction and conservative treatment was continued. Patients in which the contrast failed to reach large bowel within 24 h were considered to have complete obstruction and laparotomy was performed. RESULTS: Two hundred and twelve patients with 245 episodes of adhesive obstruction were included. Fifteen patients were operated on soon after admission due to fear of strangulation. One hundred and eighty-six episodes of obstruction showed improvement in the initial 48 h and conservative treatment was continued. Two patients had subsequent operations because of persistent obstruction. Forty-four episodes of obstruction showed no improvement within 48 h and gastrografin was administered. Seven patients underwent complete obstruction surgery. Partial obstruction was demonstrated in 37 other cases, obstruction resolved subsequently in all of them except one patient who required laparotomy because of persistent obstruction. The overall operative rate in this study was 10%. There was no complication that could be attributed to the use of gastrografin. CONCLUSION: The use of gastrografin in adhesive small bowel obstruction after unsuccessful conservative treatment is safe and reduces the need for suraical intervention 展开更多
关键词 gastrografin adhesIONS intestinal obstruction
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泛影葡胺联合生长抑素治疗粘连性肠梗阻的临床应用价值 被引量:1
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作者 王淼 江守军 赵勇 《中国实用医药》 2016年第29期38-39,共2页
目的探讨泛影葡胺联合生长抑素治疗粘连性肠梗阻(AIO)的应用价值。方法 59例AIO患者,随机分为A组(30例)与B组(29例)。A组在常规治疗的基础上给予生长抑素治疗,B组在A组治疗的基础上给予泛影葡胺治疗,比较两组治疗效果。结果 A组治愈率为... 目的探讨泛影葡胺联合生长抑素治疗粘连性肠梗阻(AIO)的应用价值。方法 59例AIO患者,随机分为A组(30例)与B组(29例)。A组在常规治疗的基础上给予生长抑素治疗,B组在A组治疗的基础上给予泛影葡胺治疗,比较两组治疗效果。结果 A组治愈率为80.00%,B组治愈率为79.31%,两组比较差异无统计学意义(P>0.05)。B组症状改善时间、肛门排气时间、排便时间、住院时间明显少于A组(P<0.05)。结论泛影葡胺联合生长抑素治疗AIO见效快、安全,值得推广应用。 展开更多
关键词 粘连性肠梗阻 泛影葡胺 生长抑素
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经口泛影葡胺对粘连性小肠不全梗阻疗效的前瞻性研究 被引量:22
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作者 姜从桥 李仕青 +2 位作者 程庆君 任景兰 张先印 《中国实用外科杂志》 CSCD 北大核心 1999年第11期666-667,共2页
目的 探讨泛影葡胺在急性粘连性小肠不全性梗阻的治疗作用,并与甘露醇及常规的保守治疗方法作前瞻性研究。方法 对109 例急性粘连性小肠不全梗阻117 例进行分析,随机将病人分成泛影葡胺组37 例41次经胃管注入76 % 泛... 目的 探讨泛影葡胺在急性粘连性小肠不全性梗阻的治疗作用,并与甘露醇及常规的保守治疗方法作前瞻性研究。方法 对109 例急性粘连性小肠不全梗阻117 例进行分析,随机将病人分成泛影葡胺组37 例41次经胃管注入76 % 泛影葡胺溶液100ml,甘露醇组35 例36 次经胃管注入10 % 甘露醇溶液200ml,对照组37 例40 次一般保守治疗。观察肠梗阻缓解时间,手术及住院时间。结果 平均第一次排便时间G 组6-3 小时,M 组16-5 小时,C组27-3 小时(G:M,P < 0-05 ;B:C, P< 0-02 ;G:C, P < 0-01) 。G 组3 次,M 组6 次,C 组9 次经治疗无效而手术,差异无统计学意义。各组对治疗有效平均住院时间分别为G 组2-9 天,M 组3-7 天,C 组4-5天(G:C, P< 0-01) 。结论 经口泛影葡胺对急性小肠不全性梗阻是一种安全有效的治疗方法,较目前临床上采用的方法,它能明显缩短肠梗阻缓解及住院时间,同时还为早期手术提供线索。 展开更多
关键词 肠梗阻 小肠 粘连性 泛影葡胺 口服 APSBO
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