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Abdominal cocoon syndrome-a rare culprit behind small bowel ischemia and obstruction:Three case reports 被引量:1
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作者 Witcha Vipudhamorn Tawan Juthasilaparut +2 位作者 Pawit Sutharat Suwan Sanmee Ekkarin Supatrakul 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第3期955-965,共11页
BACKGROUND Abdominal cocoon syndrome(ACS)represents a category within sclerosing encapsulating peritonitis,characterized by the encapsulation of internal organs with a fibrous,cocoon-like membrane of unknown origin,re... BACKGROUND Abdominal cocoon syndrome(ACS)represents a category within sclerosing encapsulating peritonitis,characterized by the encapsulation of internal organs with a fibrous,cocoon-like membrane of unknown origin,resulting in bowel obstruction and ischemia.Diagnosing this condition before surgery poses a cha-llenge,often requiring confirmation during laparotomy.In this context,we depict three instances of ACS:One linked to intestinal obstruction,the second exclu-sively manifesting as intestinal ischemia without any obstruction,and the final case involving a discrepancy between the radiologist and the surgeon.CASE SUMMARY Three male patients,aged 53,58,and 61 originating from Northern Thailand,arrived at our medical facility complaining of abdominal pain without any prior surgeries.Their vital signs remained stable during the assessment.The diagnosis of abdominal cocoon was confirmed through abdominal computed tomography(CT)before surgery.In the first case,the CT scan revealed capsules around the small bowel loops,showing no enhancement,along with mesenteric congestion affecting both small and large bowel loops,without a clear obstruction.The second case showed intestinal obstruction due to an encapsulated capsule on the CT scan.In the final case,a patient presented with recurring abdominal pain.Initially,the radiologist suspected enteritis as the cause after the CT scan.However,a detailed review led the surgeon to suspect encapsulating peritoneal sclerosis(ACS)and subsequently perform surgery.The surgical procedure involved complete removal of the encapsulating structure,resection of a portion of the small bowel,and end-to-end anastomosis.No complications occurred during surgery,and the patients had a smooth recovery after surgery,eventually discharged in good health.The histopathological examination of the fibrous membrane(cocoon)across all cases consistently revealed the presence of fibro-collagenous tissue,without any indications of malignancy.CONCLUSION Individuals diagnosed with abdominal cocoons commonly manifest vague symptoms of abdominal discomfort.An elevated degree of clinical suspicion,combined with the application of appropriate radiological evaluations,markedly improves the probability of identifying the abdominal cocoon before surgical intervention.In cases of complete bowel obstruction or ischemia,the established norm is the comprehensive removal of the peritoneal sac as part of standard care.Resection with intestinal anastomosis is advised solely when ischemia and gangrene have been confirmed. 展开更多
关键词 Sclerosing encapsulation peritonitis Abdominal cocoon peritoneal Fibrosis peritoneal encapsulation syndrome intestinal obstruction Surgery Case report
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Idiopathic sclerosing encapsulating peritonitis (or abdominal cocoon):A report of 5 cases 被引量:24
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作者 Ping Xu Li-Hua Chen You-Ming Li 《World Journal of Gastroenterology》 SCIE CAS CSCD 2007年第26期3649-3651,共3页
Sclerosing encapsulating peritonitis (SEP) is a rare cause of intestinal obstruction that is characterized by a thick grayish-white fibrotic membrane encasing the small bowel. SEP can be classified as idiopathic,also ... Sclerosing encapsulating peritonitis (SEP) is a rare cause of intestinal obstruction that is characterized by a thick grayish-white fibrotic membrane encasing the small bowel. SEP can be classified as idiopathic,also known as abdominal cocoon,or secondary. It is difficult to make a definite pre-operative diagnosis. We experienced five cases of abdominal cocoon,and the case files were reviewed retrospectively for the clinical presentation,operative findings and outcome. All the patients presented with acute,subacute and chronic intestinal obstruction. Computed tomography (CT) showed characteristic findings of small bowel loops congregated to the center of the abdomen encased by a soft-tissue density mantle in four cases. Four cases had an uneventful post-operative period,one case received second adhesiolysis due to persistent ileus. The imaging techniques may facilitate pre-operative diagnosis. Surgery is important in the management of SEP. 展开更多
关键词 Sclerosing encapsulating peritonitis Idiopathic Abdominal cocoon intestinal obstruction Adhesiolysis
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Sclerosing encapsulating peritonitis in a liver transplant patient: A case report 被引量:4
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作者 Chien-Hua Lin Jyh-Cherng Yu +1 位作者 Cheng-Jueng Chen Chung-Bao Hsieh 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第34期5412-5413,共2页
We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation, Urgent surgical intervention followi... We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation, Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during an initial PVS. However, intestinal obstruction developed 2 was found upon exploration. This is the first reported case of cocoon abdomen caused by PVS and exacerbated by liver transplantation. 展开更多
关键词 Sclerosing encapsulating peritonitis Cocoon abdomen intestinal obstruction Liver transplantation
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Idiopathic sclerosing encapsulating peritonitis:Abdominal cocoon 被引量:18
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作者 Jenny N Tannoury Bassam N Abboud 《World Journal of Gastroenterology》 SCIE CAS CSCD 2012年第17期1999-2004,共6页
Abdominal cocoon,the idiopathic form of sclerosing encapsulating peritonitis,is a rare condition of unknown etiology that results in an intestinal obstruction due to total or partial encapsulation of the small bowel b... Abdominal cocoon,the idiopathic form of sclerosing encapsulating peritonitis,is a rare condition of unknown etiology that results in an intestinal obstruction due to total or partial encapsulation of the small bowel by a f ibrocollagenous membrane.Preoperative diagnosis requires a high index of clinical suspicion.The early clinical features are nonspecif ic,are often not recognized and it is diff icult to make a def inite pre-operative diagnosis.Clinical suspicion may be generated by the recurrent episodes of small intestinal obstruction combined with relevant imaging f indings and lack of other plausible etiologies.The radiological diagnosis of abdominal cocoon may now be conf idently made on computed tomography scan.Surgery is important in the management of this disease.Careful dissection and excision of the thick sac with the release of the small intestine leads to complete recovery in the vast majority of cases. 展开更多
关键词 peritonitis Sclerosis Encapsulate intestinal obstruction Computed tomography scan Surgery
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Surgical timing for primary encapsulating peritoneal sclerosis: A case report and review of literature 被引量:1
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作者 Peng Deng Long-Xin Xiong +4 位作者 Ping He Jian-Hua Hu Qi-Xu Zou Shi-Lian Le Sen-Lin Wen 《World Journal of Gastrointestinal Surgery》 SCIE 2022年第4期352-361,共10页
BACKGROUND Primary encapsulating peritoneal sclerosis(EPS)is a rare but devastating disease that causes fibrocollagenous cocoon-like encapsulation of the bowel,resulting in bowel obstruction.The pathogenesis,preventio... BACKGROUND Primary encapsulating peritoneal sclerosis(EPS)is a rare but devastating disease that causes fibrocollagenous cocoon-like encapsulation of the bowel,resulting in bowel obstruction.The pathogenesis,prevention,and treatment strategies of EPS remain unclear so far.Since most patients are diagnosed during exploratory laparotomy,for the non-surgically diagnosed patients with primary EPS,the surgical timing is also uncertain.CASE SUMMARY A 44-year-old female patient was referred to our center on September 6,2021,with complaints of abdominal distention and bilious vomiting for 2 d.Physical examination revealed that the vital signs were stable,and the abdomen was slightly distended.Computerized tomography scan showed a conglomerate of multiple intestinal loops encapsulated in a thick sac-like membrane,which was surrounded by abdominal ascites.The patient was diagnosed with idiopathic EPS.Recovery was observed after abdominal paracentesis,and the patient was discharged on September 13 after the resumption of a normal diet.This case raised a question:When should an exploratory laparotomy be performed on patients who are non-surgically diagnosed with EPS.As a result,we conducted a review of the literature on the clinical manifestations,intraoperative findings,surgical methods,and therapeutic effects of EPS.CONCLUSION Recurrent intestinal obstructions and abdominal mass combined with the imaging of encapsulated bowel are helpful in diagnosing idiopathic EPS.Small intestinal resection should be avoided. 展开更多
关键词 Primary encapsulating peritoneal sclerosis Abdominal cocoon intestinal obstruction Case report
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Encapsulating Peritoneal Sclerosis: A Rare Devastating Peritoneal Disease: Case Series and Literature Review
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作者 Muftah Othman Hassan Al Malki +3 位作者 Fadwa Al Ali Hanan Farghaly Muhammed Asim Omar Fituri 《Open Journal of Nephrology》 2019年第4期115-126,共12页
Background: Encapsulating peritoneal sclerosis is a rare but life-threatening condition in peritoneal dialysis. It is associated with extensive thickening and fibrosis of the peritoneum resulting in recurrent small bo... Background: Encapsulating peritoneal sclerosis is a rare but life-threatening condition in peritoneal dialysis. It is associated with extensive thickening and fibrosis of the peritoneum resulting in recurrent small bowel obstructions and malnutrition. Herein we present case series of encapsulating peritoneal sclerosis diagnosed and treated in a large center of peritoneal dialysis in the State of Qatar followed by literature review to increase the awareness of physicians to it. Case Presentation: The data were collected retrospectively from 180 peritoneal dialysis patients at Hamad General Hospital, Doha, Qatar, between 2008 and 2016. The diagnosis of encapsulating peritoneal sclerosis was based on clinical and radiological features. Seven patients (3.8%) were diagnosed with encapsulating peritoneal sclerosis. The mean age of the patients was 49 years (range, 23 to 65 years). The mean duration of peritoneal dialysis was 6 years (range, 3 to 7 years). The mean peritonitis episodes were 1.8 (range 1 to 4 episodes). Five patients were diagnosed with encapsulating peritoneal sclerosis after stopping peritoneal dialysis, and two patients diagnosed while they were on peritoneal dialysis treatment. Five patients are still alive and were treated with oral prednisolone and tamoxifen. Two patients underwent adhesiolysis surgery, one of them died due to recurrent sepsis and malnutrition. Another patient died because of cardiac arrest during hemodialysis. The overall mortality rate was 28.5% in our series. Conclusions: Encapsulating peritoneal sclerosis is a rare and life-threatening peritoneal disease in chronic peritoneal dialysis patients. It requires high index of suspicion for early diagnosis and treatment. 展开更多
关键词 Encapsulating peritoneal SCLEROSIS peritoneal dialysis BOWEL obstruction
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A Case of Pelvic Floor Peritoneal Hernia after Miles’ Surgery
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作者 Zhengwen Xu Fugen Li +3 位作者 Meng Sun Chuan Qian Wenjun Luo Xiaorong Zhu 《Surgical Science》 2022年第4期246-250,共5页
Objective: To investigate the causes and preventive measures of pelvic floor peritoneal hernia after transabdominal perineal radical resection of rectal cancer. Patients and Methods: A 68-year-old patient with progres... Objective: To investigate the causes and preventive measures of pelvic floor peritoneal hernia after transabdominal perineal radical resection of rectal cancer. Patients and Methods: A 68-year-old patient with progressive exacerbation of Miles’ postoperative intestinal obstruction was retrospectively analyzed. Conservative treatment was ineffective, and surgery was performed again. Surgery confirmed that the obstruction was caused by a pelvic floor peritoneal hernia. The original reconstruction peritoneal suture needle spacing was too wide, resulting in peritoneal hiatus. Results: The early postoperative intestinal obstruction in this patient was not caused by inflammatory intestinal obstruction, stenosis of stoma, and intestinal adhesion, but by the formation of pelvic floor peritoneal hernia. Conclusion: Pelvic floor peritoneal hernia should not be ignored in the early stage of intestinal obstruction after Miles’ operation. Improper suture during pelvic floor peritoneal reconstruction is the main cause of pelvic floor peritoneal hernia. 展开更多
关键词 Miles’ Operation Pelvic Floor peritoneal Hernia intestinal obstruction
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持续不卧床腹膜透析患者因梗阻性脓肾致腹膜透析相关性腹膜炎1例并文献复习
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作者 吴晓凤 黎渐英 +3 位作者 李剑波 林建雄 刘苑莹 郭群英 《中国血液净化》 CSCD 2024年第1期75-77,共3页
腹膜透析(peritoneal dialysis,PD)相关性腹膜炎通常由于接触污染或者出口处感染引起。也有少部分腹膜炎起因于肠道疾病,其中最常见的病因包括胃肠道穿孔、缺血性肠病和胆囊炎等。因梗阻性脓肾引起的腹膜炎极为罕见。该文报道了1例72岁... 腹膜透析(peritoneal dialysis,PD)相关性腹膜炎通常由于接触污染或者出口处感染引起。也有少部分腹膜炎起因于肠道疾病,其中最常见的病因包括胃肠道穿孔、缺血性肠病和胆囊炎等。因梗阻性脓肾引起的腹膜炎极为罕见。该文报道了1例72岁男性腹膜透析患者因梗阻性左肾积脓引起的继发性腹膜炎,行左肾盂造瘘引流术和左肾切除术,最后未拔除腹膜透析管而继续腹膜透析治疗。随访8个月未再次发生腹膜炎。本研究报道了国内首例因梗阻性脓肾引起的持续不卧床腹膜透析合并继发性腹膜炎的病例,以提醒临床医生腹膜透析继发性腹膜炎可能的病因,为临床治疗决策提供依据。 展开更多
关键词 腹膜透析 继发性腹膜炎 梗阻性肾积脓
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罗沙司他对腹膜透析大鼠腹膜HIF-1α/VEGF信号通路表达及纤维化的影响
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作者 张静 刘张晨 +4 位作者 李小军 刘海义 李思情 阿依江·马合沙提 任荣 《新疆医科大学学报》 CAS 2024年第11期1446-1451,共6页
目的评估罗沙司他(Roxadustat,ROX)对腹膜透析(Peritoneal dialysis,PD)大鼠腹膜组织的缺氧诱导因子-1α(Hypoxia-inducible factors-1α,HIF-1α)以及血管内皮生长因子(Vascular endothelial growth factor,VEGF)表达的影响,同时探讨... 目的评估罗沙司他(Roxadustat,ROX)对腹膜透析(Peritoneal dialysis,PD)大鼠腹膜组织的缺氧诱导因子-1α(Hypoxia-inducible factors-1α,HIF-1α)以及血管内皮生长因子(Vascular endothelial growth factor,VEGF)表达的影响,同时探讨其对腹膜纤维化程度的潜在作用及其机制。方法购入30只雄性SPF级大鼠,采用5/6肾脏切除法成功构建尿毒症腹膜透析大鼠模型27只,随机分为空白对照组、PD组、PD+ROX组(联合给予5 mg/kg ROX,每周3次),每组9只,持续给药1个月,在灌胃后6、12、24 h以及4周时,采用ELISA法检测腹膜透析液、血液中HIF-1α和VEGF的浓度。利用HE和Masson染色观察大鼠腹膜组织病理变化,WB和免疫组化检测腹膜组织中HIF-1α、VEGF蛋白表达变化。结果HE和Masson染色观察各组大鼠腹膜组织,与空白对照组比较,PD组大鼠的腹膜组织出现了明显的纤维化和血管增生现象;与PD组相比,PD+ROX组大鼠的腹膜组织纤维化和血管增生现象明显改善。PD组腹膜组织中HIF-1α和VEGF蛋白表达水平显著高于空白对照组(P均<0.05),增加ROX干预后,PD+ROX组大鼠腹膜组织中HIF-1α和VEGF蛋白表达水平显著降低(P均<0.05)。PD+ROX组血清中HIF-1α和VEGF浓度均高于空白对照组和PD组(P均<0.05)。PD+ROX组腹膜透析液中HIF-1α和VEGF浓度均低于空白对照组和PD组(P均<0.05)。结论ROX治疗能有效降低腹膜组织及腹膜透析液中的HIF-1α和VEGF表达水平,缓解由葡萄糖腹膜透析引起的腹膜组织纤维化和血管增生。同时,血清中HIF-1α和VEGF水平的提升有助于改善腹膜组织的缺氧状况,抑制HIF-1α/VEGF信号通路,对抗腹膜纤维化。 展开更多
关键词 罗沙司他 腹膜透析 腹膜组织纤维化 HIF-1α/VEGF信号通路
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腹膜透析相关性腹膜炎患者肠道菌群变化研究 被引量:1
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作者 何阶德 黄朦 +2 位作者 黄存军 刘红玉 梁航 《检验医学与临床》 CAS 2024年第7期923-928,共6页
目的探讨肠道菌群紊乱与腹膜透析相关性腹膜炎的关系。方法收集2022年1—12月于该院进行规律腹膜透析的85例患者,根据是否发生腹膜透析相关性腹膜炎分为腹膜炎组(40例)和非腹膜炎组(45例)。比较两组肠道菌群分布差异,以及肠道菌群紊乱... 目的探讨肠道菌群紊乱与腹膜透析相关性腹膜炎的关系。方法收集2022年1—12月于该院进行规律腹膜透析的85例患者,根据是否发生腹膜透析相关性腹膜炎分为腹膜炎组(40例)和非腹膜炎组(45例)。比较两组肠道菌群分布差异,以及肠道菌群紊乱与腹膜炎发生的相关性。结果腹膜炎组患者肠道Eubacterium菌、罗氏菌、Absiella菌、毛螺菌丰度高于非腹膜炎组,阿克曼氏菌、肠球菌、萨特氏菌、普雷沃氏菌丰度低于非腹膜炎组,差异均有统计学意义(P<0.05)。相关性分析发现,肠道中有害菌群丰度与腹膜炎血液指标白细胞计数、中性粒细胞百分比以及C反应蛋白呈正相关(P<0.05),肠道中有益菌群丰度与白细胞计数、中性粒细胞百分比以及C反应蛋白呈负相关(P<0.05)。此外,粪便中短链脂肪酸(乙酸、丙酸和丁酸)水平与白细胞计数、中性粒细胞百分比以及C反应蛋白呈负相关(P<0.05),与肠道中肠球菌、阿克曼氏菌、萨特氏菌、普雷沃氏菌丰度呈正相关(P<0.05)。结论腹膜透析相关性腹膜炎的发生与患者肠道菌群紊乱密切相关,肠道菌群和粪便短链脂肪酸检测对腹膜透析相关性腹膜炎具有一定的辅助检测价值。 展开更多
关键词 腹膜透析 腹膜炎 肠道菌群 炎症因子 短链脂肪酸
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复方嗜酸乳杆菌片对腹膜透析患者胃肠道症状的疗效及肠道菌群的影响
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作者 闫慧玲 王宇晖 +1 位作者 翁宁 童孟立 《浙江医学》 CAS 2024年第10期1027-1033,I0004,共8页
目的观察伴有胃肠道症状的腹膜透析患者口服复方嗜酸乳杆菌片治疗的效果,以及治疗前后肠道菌群的变化。方法回顾性选取2021年6至9月在杭州市中医院腹膜透析中心行持续性非卧床腹膜透析治疗并伴有胃肠道症状的患者40例。患者在常规治疗(... 目的观察伴有胃肠道症状的腹膜透析患者口服复方嗜酸乳杆菌片治疗的效果,以及治疗前后肠道菌群的变化。方法回顾性选取2021年6至9月在杭州市中医院腹膜透析中心行持续性非卧床腹膜透析治疗并伴有胃肠道症状的患者40例。患者在常规治疗(降血压、调脂、降糖,以及纠正甲状旁腺功能亢进、电解质紊乱、贫血等)基础上联合口服复方嗜酸乳杆菌片治疗6个月。通过评估患者治疗前和治疗后胃肠道症状评定量表(GSRS)评分观察对胃肠道症状的疗效。收集患者治疗前后的粪便样本,采用16S核糖体DNA(16S rDNA)技术测定患者治疗前后肠道菌群多样性、物种组成差异。结果复方嗜酸乳杆菌片对患者胃肠道症状的治疗有效率分别为便秘80.6%,消化不良72.7%,腹痛82.6%,腹泻92.3%,反流72.7%,总体有效率为85.0%。消化不良、腹痛、腹泻、反流症群GSRS评分与特定肠道菌群在属水平丰度上均存在一定相关性(均P<0.05)。患者治疗前后肠道菌群的Alpha多样性及Beta多样性差异均有统计学意义(均P<0.05)。物种差异LEfSe分析提示肠道菌群在治疗前后共有2个门、3个纲、3个目、1个科、1个属、1个种的显著差异物种。细菌表型预测提示治疗后肠道菌群中好氧表型、耐应激性表型增加,厌氧表型下降。结论复方嗜酸乳杆菌片能改善腹膜透析患者胃肠道症状和肠道菌群失调。 展开更多
关键词 益生菌 肠道菌群 腹膜透析 16S核糖体DNA
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维持性腹膜透析并发结肠瘘、膀胱瘘1例并文献复习
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作者 徐若云 刘琼 +1 位作者 贾敏楠 刘冰 《临床荟萃》 CAS 2024年第11期1016-1020,共5页
目的探讨维持性腹膜透析并发结肠穿孔、膀胱穿孔的临床特征及治疗方法。方法回顾性分析维持性腹膜透析并发结肠穿孔、膀胱穿孔1例临床资料及诊治经过,并进行文献复习。结果患者老年男性,主因“发现血肌酐升高9年,维持性腹膜透析1年,导... 目的探讨维持性腹膜透析并发结肠穿孔、膀胱穿孔的临床特征及治疗方法。方法回顾性分析维持性腹膜透析并发结肠穿孔、膀胱穿孔1例临床资料及诊治经过,并进行文献复习。结果患者老年男性,主因“发现血肌酐升高9年,维持性腹膜透析1年,导管功能不良5天”入院。既往2022年2月确诊为直肠癌,行直肠癌根治术、放疗,后停止腹膜透析,改为规律血液透析,2022年9月出现腹膜透析导管功能不良,考虑并发肠穿孔。诊断为结肠瘘、膀胱瘘,给予抗感染治疗后病情有所好转,因直肠癌转移于院外死亡。结论对于合并肠道肿瘤、腹部手术史及放疗史的腹膜透析患者应术前拔除腹膜透析管,改为血液透析。当维持性腹膜透析患者出现腹痛、导管引流障碍、灌入腹膜透析液后出现大量水样腹泻等症状时,应警惕肠穿孔发生,一旦确诊,尽早拔管及时改为血液透析。 展开更多
关键词 腹膜透析 肠穿孔 膀胱穿孔
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基于16SrRNA基因测序对腹膜透析患者肠道微生态环境特征分析研究
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作者 廖海君 谭菲 彭红霞 《当代医学》 2024年第10期129-132,共4页
目的探讨基于16SrRNA基因测序对腹膜透析患者肠道微生态环境的特征分析。方法选取2019年2—9月赣州市人民医院收治的60例接受规律性腹膜透析的患者作为观察组,另选取2019年5月于本院进行常规体检的60名受试者作为对照组。对所有受试者... 目的探讨基于16SrRNA基因测序对腹膜透析患者肠道微生态环境的特征分析。方法选取2019年2—9月赣州市人民医院收治的60例接受规律性腹膜透析的患者作为观察组,另选取2019年5月于本院进行常规体检的60名受试者作为对照组。对所有受试者进行粪便提取和检测。比较两组炎症指标水平[C反应蛋白CRP)、超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)],分析观察组16SrRNA基因测序结果和肠道微生态检测结果。结果观察组CRP、hs-CRP、IL-6水平均高于对照组,TNF-α水平低于对照组,差异有统计学意义(P<0.05)。60例患者中,腹膜透析透出液培养检出革兰阳性菌41例,阳性率为68.3%;观察组革兰阴性菌22例(其中大肠埃希菌14例),革兰阳性菌38例(其中表皮葡萄球菌13例,头状葡萄球菌、唾液链球菌均5例)。结论16SrRNA基因测序可准确评估腹膜透析患者的肠道情况,健康人群肠道微生物的群落较复杂,但基本稳定,为肠道菌群结构和功能研究提供了参考依据。 展开更多
关键词 16SrRNA基因测序 腹膜透析 肠道微生态环境 特征分析
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原发性腹茧症的影像学特征、治疗及预后分析 被引量:15
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作者 李有国 宋茂民 +2 位作者 白日星 郑建伟 袁辉生 《首都医科大学学报》 CAS 2012年第1期74-78,共5页
目的研究原发性腹茧症的影像学特点和预后影响因素。方法回顾性分析首都医科大学附属北京天坛医院普外科2000年1月~2009年12月收治的原发性腹茧症患者的临床特征、CT检查资料、治疗方法和预后。结果全部6例均表现为肠梗阻。腹部X线平... 目的研究原发性腹茧症的影像学特点和预后影响因素。方法回顾性分析首都医科大学附属北京天坛医院普外科2000年1月~2009年12月收治的原发性腹茧症患者的临床特征、CT检查资料、治疗方法和预后。结果全部6例均表现为肠梗阻。腹部X线平片可见小肠扩张积气肠袢及液气平面。腹部CT检查可见小肠扩张聚集成团,其周围似可见增厚的包膜包裹。腹部B超检查均发现小肠肠管部分扩张,4例可见少量腹水。5例进行了消化道钡餐检查,均提示回肠远端钡剂通过缓慢,其中1例提示回肠远端狭窄,另1例造影后出现完全性肠梗阻。剖腹探查术中均显示全部或部分小肠被一层灰白色致密坚韧的纤维膜包裹,大网膜缺如。均行部分纤维膜剥除、粘连松解术等,1例同时行部分小肠切除术。术后6例全部治愈。结论消化道造影和腹部CT检查对于原发性腹茧症具有重要的诊断价值。手术是安全有效的治疗方法。 展开更多
关键词 腹茧症 肠梗阻 腹膜疾病
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腹膜透析并发包裹性腹膜硬化症1例报道 被引量:3
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作者 张贺 李振元 +6 位作者 严豪 张敏芳 王琴 王玲 倪兆慧 钱家麒 方炜 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2016年第11期1682-1684,共3页
目的·提高对腹膜透析相关的包裹性腹膜硬化症的认识和防治。方法·分析1例退出腹膜透析后发生包裹性腹膜硬化症并给予药物治疗的病例。结果·1例因腹膜超滤衰竭退出腹膜透析的血液透析患者出现肠梗阻症状,结合影像学结果,... 目的·提高对腹膜透析相关的包裹性腹膜硬化症的认识和防治。方法·分析1例退出腹膜透析后发生包裹性腹膜硬化症并给予药物治疗的病例。结果·1例因腹膜超滤衰竭退出腹膜透析的血液透析患者出现肠梗阻症状,结合影像学结果,诊断为包裹性腹膜硬化症,给予药物治疗结合全胃肠外营养,临床症状有明显改善。结论·包裹性腹膜硬化症是腹透患者的严重并发症,早期诊断困难,预后差,严重影响着腹膜透析患者的生存质量。药物及手术治疗各有优缺点,应及时发现尽早治疗。 展开更多
关键词 包裹性腹膜硬化症 腹膜透析 肠梗阻
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加味参苓白术散治疗脾虚瘀浊型持续性不卧床腹膜透析合并蛋白质-能量消耗的临床研究 被引量:9
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作者 吕勇 张磊 +1 位作者 宋蓓蓓 王亿平 《南京中医药大学学报》 CAS CSCD 北大核心 2022年第3期193-198,共6页
目的观察加味参苓白术散治疗脾虚瘀浊型持续性不卧床腹膜透析(Continuous ambulatory peritoneal dialysis,CAPD)合并蛋白质-能量消耗(Protein-energy wasting,PEW)的临床疗效及对机体微炎症状态的影响。方法91例脾虚瘀浊型CAPD合并PEW... 目的观察加味参苓白术散治疗脾虚瘀浊型持续性不卧床腹膜透析(Continuous ambulatory peritoneal dialysis,CAPD)合并蛋白质-能量消耗(Protein-energy wasting,PEW)的临床疗效及对机体微炎症状态的影响。方法91例脾虚瘀浊型CAPD合并PEW患者随机分为治疗组45例、对照组46例,每组各脱落3例。对照组应用CAPD、口服复方α-酮酸及常规对症治疗,治疗组在对照组治疗基础上予加味参苓白术散口服,疗程均为12周。治疗前后观察2组患者中医证候积分和营养不良-炎症(Malnutrition-inflammation score,MIS)、总尿素清除指数(Kt/V)评分的变化,检测2组患者治疗前后外周血营养相关指标[血红蛋白(Hemoglobin,HGB)、血清白蛋白(Albumin,ALB)、转铁蛋白(Transferrin,TRF)、前白蛋白(Prealbumin,PA)]及血清微炎症指标[白介素6(Interleukin-6,IL-6)、超敏C反应蛋白(Hypersensitive c-reactive protein,hs-CRP)、肿瘤坏死因子α(Tumor necrosis factorα,TNF-α)和白介素10(Interleukin-10,IL-10)]水平变化情况。结果治疗后,治疗组中医证候积分明显下降(P<0.01),优于对照组(P<0.01),治疗组中医临床疗效总有效率显著优于对照组(P<0.05);治疗组MIS显著降低、Kt/V明显增加(P<0.01),优于对照组(P<0.05,P<0.01);治疗组ALB、PA、TRF及HGB含量均显著增加(P<0.01),对照组ALB、PA含量明显增加(P<0.01),治疗组优于对照组(P<0.05,P<0.01);2组患者血清hs-CRP、IL-6、TNF-α水平均明显降低(P<0.01),IL-10水平均升高(P<0.05,P<0.01),治疗组优于对照组(P<0.05,P<0.01)。结论加味参苓白术散能够显著改善脾虚瘀浊型CAPD合并PEW患者的中医证候,改善患者PEW,缓解机体微炎症状态,提高腹膜透析充分性。 展开更多
关键词 腹膜透析 加味参苓白术散 蛋白质-能量消耗 微炎症状态 脾虚瘀浊型
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全小肠分离排列术治疗严重结核性腹膜炎合并完全性小肠梗阻44例分析 被引量:4
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作者 何建苗 蒲永东 +4 位作者 海龙 杨波 董立国 曹志宇 刘卫平 《解放军医学杂志》 CAS CSCD 北大核心 2006年第12期1199-1200,共2页
目的探讨严重结核性腹膜炎合并完全性小肠梗阻的治疗方法。方法对解放军总医院第二附属医院1996年6月~2005年6月收治的44例患者进行回顾性分析。结果44例患者均为严重结核性腹膜炎合并小肠梗阻,其中术前确诊36例,8例为术后证实。全... 目的探讨严重结核性腹膜炎合并完全性小肠梗阻的治疗方法。方法对解放军总医院第二附属医院1996年6月~2005年6月收治的44例患者进行回顾性分析。结果44例患者均为严重结核性腹膜炎合并小肠梗阻,其中术前确诊36例,8例为术后证实。全组病例均经内科治疗无效后行剖腹探查、全小肠分离排列术,43例术后肠梗阻症状消失,无复发,1例死亡。其中2例术后合并肠瘘,1例治愈,1例死亡。结论结核性腹膜炎合并完全性小肠梗阻内科治疗多无效,而全小肠分离排列术则是一种有效的治疗方法,术前术后抗结核治疗和营养支持治疗是减少术后并发症、彻底治愈的关键。 展开更多
关键词 结核 腹膜 肠梗阻 外科手术
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肠排列术在严重结核性腹膜炎合并完全性小肠梗阻中的应用 被引量:8
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作者 何建苗 蒲永东 +3 位作者 海龙 杨波 董立国 曹志宇 《临床外科杂志》 2007年第5期331-332,共2页
目的探讨严重结核性腹膜炎合并完全性小肠梗阻的治疗方法。方法对我院1996年6月至2005年6月收治的44例严重结核性腹膜炎合并小肠梗阻患者进行回顾性分析。结果术前确诊36例,8例为术后证实。全组病例均经内科治疗无效后行剖腹探查全小肠... 目的探讨严重结核性腹膜炎合并完全性小肠梗阻的治疗方法。方法对我院1996年6月至2005年6月收治的44例严重结核性腹膜炎合并小肠梗阻患者进行回顾性分析。结果术前确诊36例,8例为术后证实。全组病例均经内科治疗无效后行剖腹探查全小肠分离排列术,43例术后痊愈无复发,2例术后合并肠瘘,其中1例死亡。结论结核性腹膜炎合并完全性小肠梗阻内科治疗多无效,全小肠分离排列术是一种治疗结核性腹膜炎合并完全性小肠梗阻的有效方法。术前术后抗结核治疗和营养支持治疗是减少术后并发症、彻底治愈的关键。 展开更多
关键词 结核性腹膜炎 肠梗阻 治疗
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肠道微生态制剂对老年慢性肾衰竭腹膜透析病人残余肾功能、微炎症及氧化应激的影响 被引量:9
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作者 刘翠兰 金玉杰 +3 位作者 韩小丽 刘圣君 郭宝珠 刘俊芬 《实用老年医学》 CAS 2021年第4期358-361,共4页
目的观察老年慢性肾衰竭终末期腹膜透析病人经肠道微生态制剂治疗的效果。方法选取2019年1月至2020年1月期间于我院接受腹膜透析的100例老年慢性肾衰竭终末期病人,采用数字奇偶法分为观察组(奇数)与对照组(偶数),每组各50例。对照组行... 目的观察老年慢性肾衰竭终末期腹膜透析病人经肠道微生态制剂治疗的效果。方法选取2019年1月至2020年1月期间于我院接受腹膜透析的100例老年慢性肾衰竭终末期病人,采用数字奇偶法分为观察组(奇数)与对照组(偶数),每组各50例。对照组行腹膜透析+常规治疗,观察组接受腹膜透析+常规治疗+肠道微生态制剂治疗,2组均治疗2个月。检测并比较2组治疗前后残余肾功能、微炎症状态(CRP、hs-CRP、IL-6及TNF-α)及氧化应激反应[丙二醛(MDA)、超氧化物歧化酶(SOD)及谷胱甘肽过氧化酶(GSH-Px)]水平;比较治疗期间2组腹膜炎发生率。结果治疗2个月后,2组残余肾功能均较治疗前改善,且观察组改善更显著(P<0.05);2组CRP、hs-CRP、IL-6、TNF-α、MDA、SOD及GSH-Px水平均较治疗前改善,且观察组改善更显著(P<0.05);治疗期间观察组腹膜炎发生率显著低于对照组(P<0.05)。结论老年慢性肾衰竭终末期腹膜透析病人联合使用肠道微生态制剂,有助于改善病人残余肾功能,减轻全身微炎症反应及氧化应激程度,降低腹膜炎发生率,临床应用价值高。 展开更多
关键词 慢性肾衰竭 腹膜透析 肠道微生态制剂 残余肾功能 微炎症 氧化应激
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产前超声在诊断胎儿消化道异常中的应用价值 被引量:8
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作者 李洁 樊慧 +1 位作者 栗河舟 娄晓民 《河南医学研究》 CAS 2011年第4期446-448,共3页
目的:研究产前超声在诊断胎儿消化道异常方面的声像图表现及重要应用价值。方法:对2009年10月至2011年6月在我院进行产前超声检查的32 453例孕妇中127例胎儿消化道畸形的超声表现及其临床资料进行回顾性分析。结果:诊断出胎儿消化系统... 目的:研究产前超声在诊断胎儿消化道异常方面的声像图表现及重要应用价值。方法:对2009年10月至2011年6月在我院进行产前超声检查的32 453例孕妇中127例胎儿消化道畸形的超声表现及其临床资料进行回顾性分析。结果:诊断出胎儿消化系统畸形共127例,包括:食管闭锁3例,十二指肠闭锁与狭窄57例,肠管扩张43例,胎粪性腹膜炎24例。结论:产前超声在诊断胎儿消化道异常方面的有重要应用价值,可为产前咨询和临床处理提供重要依据。 展开更多
关键词 超声 胎儿 肠梗阻 肠管扩张 胎粪性腹膜炎
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