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Releasing of Cupric Ion of Three types of Copper-bearing Intrauterine Contraceptive Device in Simulated UterineFluid 被引量:3
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作者 Jie GAO Ying LI +1 位作者 Jian-ping LIU Xuan GU 《Journal of Reproduction and Contraception》 CAS 2007年第1期33-39,共7页
Objective To compare the cupric ion releasing in vitro o.f the three IUDs. Methods The stability o.f cupric ion releasing o.f IUDs including TCu 380.4 IUD (TCu 380A), Multiload Cu375 IUD (MCu 375) and Yuangong 365... Objective To compare the cupric ion releasing in vitro o.f the three IUDs. Methods The stability o.f cupric ion releasing o.f IUDs including TCu 380.4 IUD (TCu 380A), Multiload Cu375 IUD (MCu 375) and Yuangong 365 copper-bearing indomethacin-releasing IUD (Yuangong 365) by the determination of cupric ion releasing in simulated uterine fluid. The simulated uterine fluid was used for releasing media. Copper ion was determined by flame atomic absorption spectrometer. Results The cupric ion releasing of three IUDs were instable at the beginning and tend to be stable gradually. In the stable phase, the average level of cupric ion releasing of TCu380A, MCu375 and Yuangong 365 were 4.25±2.71-7.62±6.42 μg, 4.92±1.23 -8.62±3.08 μg and 2.19±0.40-4.68±1.66 μg, respectively. TCu380A had higher instable releasing level than those of Yuangong 365 (P〈0. 05). Conclusion TCu 380.4 and MCu 375 showed a "burst release" during the first few days and the.former was of great significance(P〈0.05). The initial cupric ion releasing of Yuangong 365 appeared to be the lowest, followed by MCu375 and TCu380A in a releasing order 展开更多
关键词 copper-bearing intrauterine contraceptive device CU-IUD the releasing ofcupric ion simulated uterine fluid flame atomic absorption spectrometer
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Pre-Clinical Experimental Studies of Indomethacin-Releasing Copper Intrauterine Device 被引量:1
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作者 曹路敏 周玉玲 +4 位作者 刘子龙 杜庆玲 李万 胡燕群 李玮 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2000年第3期249-252,共4页
Effects of two types of intrauterine device (IUD) on the prostaglandins and endothelin (ET) in uterus and on the endometrial morphology in rats and rabbits, and Cu 2+ releasing amounts of both IUDs in vitro w... Effects of two types of intrauterine device (IUD) on the prostaglandins and endothelin (ET) in uterus and on the endometrial morphology in rats and rabbits, and Cu 2+ releasing amounts of both IUDs in vitro were observed. The results showed that the inhibiting action of the indomethacin releasing copper IUD (FICu IUD) on the PGI 2 was stronger than that on the TXA 2, the ratio of 6 keto PGF 1α /TXB 2 was reduced with the increase of the doses. There were significant differences between the groups. The FICu IUD could inhibit the rising of the ET level and lighten the endometrial impairment caused by the FCu IUD, and promote copper ion release. It was suggested that indomethacin released by FICu IUD could effectively reduce abnormal uterine bleeding. 展开更多
关键词 copper intrauterine device INDOMETHACIN PROSTAGLANDINS ENDOTHELIN ENDOMETRIUM copper ion
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A comparative, randomized study of levonorgestrel Intrauterine System (LNG-IUS) vs Copper T 380 A intrauterine device applied during cesarean section
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作者 José A. López-Farfan Alicia Hernandez-Gonzalez +1 位作者 Irvin J. Vélez-Machorro Leopoldo A. Vázquez-Estrada 《Open Journal of Obstetrics and Gynecology》 2012年第2期151-155,共5页
Objective: To assess levonorgestrel-releasing intrauterine system LNG-IUS (Mirena?) application at caesarean section (CS). Design: Randomized, comparative study. Setting: Department of obstetrics and gynecology in a p... Objective: To assess levonorgestrel-releasing intrauterine system LNG-IUS (Mirena?) application at caesarean section (CS). Design: Randomized, comparative study. Setting: Department of obstetrics and gynecology in a primary reference hospital at Puebla City, Mexico. Sample: 396 women requiring CS signed informed consent and were randomly allocated to the post-placental application of LNG-IUS (198) or Copper T 380 A (198). Methods: Follow up visits at 6 weeks, and 6 and 12 months were performed. Main Outcomes Measures: IUDs expulsion, maternal and babies’ health conditions, breastfeeding and menstrual patterns, adverse effects and pregnancies. Differences between groups were analyzed by Fisher and X2 tests, Odds ratios, relative risk and 95% confidence limits, as appropriate. Results: After one year of follow up, no pregnancies were reported. The IUD expulsion rate was 4.5% in each group. LNG-IUS users had a higher incidence of amenorrhea (OR 2.5 95% CI 2.2 - 3) and menstrual patterns significantly brief and lighter than Copper T 380 A (p < 0.001) with lower incidence of dysmenorrhea (OR 0.1 95% CI 0.04 - 0.2). No detrimental effects of LNG-IUS on breastfeeding was observed and interestingly babies weights of LNG-IUS users was slightly above the average for age compared with Copper T 380 A users. This was probably related with a major proportion of women with normal ferritin serum levels (94% vs 68%) leading to better mother’s general condition. Conclusions: LNG-IUS inserted during CS provides high efficacy contraception with additional benefits, mainly reducing menstrual bleeding and doing so, faster recovery of ferrous homeostasis after CS. 展开更多
关键词 Levonorgestrel-Releasing intrauterine System Medicated IUD copper T IUD CESAREAN Section Postpartum CONTRACEPTION Ferritin Levels
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Effects of Copper-Containing Intrauterine Devices on the Endometrium
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作者 Jia-Hui Che Xiao-Ying Yao 《Reproductive and Developmental Medicine》 CSCD 2021年第1期38-43,共6页
The use of copper-containing intrauterine devices(Cu-IUDs)is a safe,effective,and long-term contraceptive method.Here,we review the effects of Cu-IUDs on subsequent pregnancy and the morphology,local coagulation funct... The use of copper-containing intrauterine devices(Cu-IUDs)is a safe,effective,and long-term contraceptive method.Here,we review the effects of Cu-IUDs on subsequent pregnancy and the morphology,local coagulation function,sensitivity to estrogen and progesterone,cell proliferation,and immune response of the endometrium.Studies on the morphology of endometrium indicate that the use of Cu-IUDs can affect the number and binding capacity of estrogen and progesterone receptors in the endometrium and reduce the response of the endometrium to estrogen and progesterone.The use of Cu-IUDs can also affect the proliferation of endometrial cells,suggesting that the aseptic inflammation caused by Cu-IUDs may differ from chronic infectious or noninfectious inflammation;this highlights that the use of Cu-IUDs provides protection against endometrial proliferative diseases.The use of Cu-IUDs increases local endometrial angiogenesis,bleeding tendency,and fibrinolytic activity,which can result in prolonged menstruation or abnormal uterine bleeding.Additionally,the use of Cu-IUDs can cause the infiltration of numerous lymphocytes,monocytes,macrophages,and other inflammatory cells around the endometrial gland and changes in endometrial immune function,immune cell function,and the number and type of immune molecules.Cu-IUD-induced decidual injury significantly increases the invasiveness of trophoblasts,further affecting the aberrant expression of their growth-,angiogenesis-,and invasion-related factors and improving the formation of the placenta.Moreover,the endometrial damage caused by Cu-IUD placement before embryo transfer can improve both clinical pregnancy and live birth rates;however,specific changes in the immune system after Cu-IUD use as well as its effects on future pregnancies require further investigation. 展开更多
关键词 CONTRACEPTION copper ENDOMETRIUM intrauterine Contraception intrauterine Device
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Cytotoxicity of six copper-bearing intrauterine devices on Chinese hamster ovary cells: the influence of frame, shape and copper surface area
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作者 Tong CHEN Ying LI +3 位作者 Wen-li ZHANG Wei-sai ZHOU Shuang-shuang ZHANG Jian-ping LIU 《Journal of Reproduction and Contraception》 CAS CSCD 2015年第3期160-172,共13页
Objective To evaluate the cytotoxicity of six commonly used copper-bearing intrauterine devices (Cu-IUDs) on Chinese hamster ovary (CHO-K1) cells and to investigate the influence of frame, shape and copper surface... Objective To evaluate the cytotoxicity of six commonly used copper-bearing intrauterine devices (Cu-IUDs) on Chinese hamster ovary (CHO-K1) cells and to investigate the influence of frame, shape and copper surface area of Cu-IUDs on cell toxicity.Methods Cu-IUDs were incubated in 10% FBS-DMEM/F12 culture medium at 37 ℃ for 24 h. The extracts were analyzed by flame atomic absorption spectrometer and were then diluted into different concentrations with culture medium. Finally, cytotoxicity of these original and diluted extracts on CHO-K1 cells was detected by cell counting kit-8 (CCK-8) assay.Results The viabilities of cells treated with the original extracts of six Cu-IUDs (TCu220C bulb, TCu220C, GCu220, GCu300, Yuangong Cu270 and Yuangong Ⅱ- 300) were all below 10% and the cupric ion concentrations in these extracts were 28.22 mg/L, 31.80 mg/L, 92.80 mg/L, 99.74 mg/L, 114.90 mg/L and 119.20 mg/L, respectively. After these original extracts were diluted, significant differences in cytotoxicity were exhibited. IUDs with larger copper surface areas (GCu300 and Yuangong Ⅱ-300) showed more cytotoxicity than those with smaller areas (GCu220 and Yuangong Cu270) respectively; When different shapes of Cu-IUDs were compared, TCu220C bulb showed lower cytotoxicity than TCu220C, and GCu300 exhibited higher toxicity than Yuangong Ⅱ-300; TCu220C displayed significantly lower cytotoxicity than GCu220 due to their differences in frames.Conclusion We presented evidence on the cytotoxic effects of copper ions released from Cu-IUDs on CHO-K1 cells and found that shape, frame together with copper surface area of Cu-IUDs had obvious influence on the cytotoxicity. 展开更多
关键词 copper-bearing intrauterine device (Cu-IUD) Chinese hamster ovary (CHO-K1) cell counting kit-8 (CCK-8) CYTOTOXICITY extract concentration influential factor
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Characteristics of High-Speed Copper Plating Films Using a Jet Flow Device
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作者 Yohei Suzuki Yushi Miyashita +4 位作者 Yasushi Umeda Christpher E.J.Cordonier Hideo Honma Osamu Takai Joo-Hyong Noh 《材料科学与工程(中英文A版)》 2019年第3期91-97,共7页
Since copper has excellent properties such as malleability and conductivity,it is widely used in the electronics field.Copper sulfate plating is expanding further in fields requiring thick deposits such as for heat di... Since copper has excellent properties such as malleability and conductivity,it is widely used in the electronics field.Copper sulfate plating is expanding further in fields requiring thick deposits such as for heat dissipation boards and bumps for stress relaxation during semiconductor packaging.In this study,high-speed copper plating at 50 A/dm2 or more was achieved using a jet flow device.In addition,as a result of comparison with the low current density film,the current density had little effect on electrical conductivity and film surface structure.On the other hand,it was confirmed that the etching rate of the high current density film was greatly increased as the crystallites on the film surface became smaller than low current density film.Increase in productivity is expected due to shorter plating time enabled by film deposition at high current density.Furthermore,the increase of etching rate is expected to contribute to the suppression of undercuts that occur when removing the seed layer during wiring and bump fabrication. 展开更多
关键词 ELECTRO copper PLATING high current density film CHARACTERISTICS JET flow DEVICE
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Level of Copper Ion in Cervical Mucus of Various Duration after Inserting VCu200IUD
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作者 刘庆喜 黄祝 潘琢如 《Journal of Reproduction and Contraception》 CAS 1996年第1期25-31,共7页
The purpose of the study was to test the effective period of VCu200 IUD.The concentration of copper ion was measured with non-flame atomic absorption spectrophotometer HITACHI-180.The average concentration of coPPer i... The purpose of the study was to test the effective period of VCu200 IUD.The concentration of copper ion was measured with non-flame atomic absorption spectrophotometer HITACHI-180.The average concentration of coPPer ion(x±s.)was 2.66±0.58μg/g cervical mucus wet weight(μg/g·M·W·W) in the first year,then gradually decreasing to 0.91±0.16μg/g·M·W·W in the fifteenth-year group of VCu200 IUD.There was an average of 0.35±0.08~0.56±0.14 μg/g·M·W·W in the control group.It showed that the concentration of copper ion was decreasing with prolongation of use of VCu200 IUD and there was statistically significant difference between VCu200 IUD group,on the one hand,and the stainless steel ring group and the control group(P<0.05~0.01)on the other hand.No difference was found between the stainless steel ring group and the control group(P>0.05).It was reported in the literature that the concentration Of copper ion in 1.0μg/ml had the action of antifertility,and it was found that the concentration of copper ion was higher than 1.0μg/ml in the tenth year after insertion of VCu200 IUD.It suggested that effective period of VCu200 IUD was at least ten years. 展开更多
关键词 Intrautering device copper ion Cervical mucus
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Using laparoscope to remove an ectopic intrauterine device in the anterior wall of urinary bladder:A case report
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作者 Shi-Xue Liu Xing-You Dong 《World Journal of Clinical Cases》 SCIE 2024年第17期3221-3225,共5页
BACKGROUND An intrauterine device(IUD)is a contraceptive device placed in the uterine cavity and is a common contraceptive method for Chinese women.However,an IUD may cause complications due to placement time,intraute... BACKGROUND An intrauterine device(IUD)is a contraceptive device placed in the uterine cavity and is a common contraceptive method for Chinese women.However,an IUD may cause complications due to placement time,intrauterine pressure and other factors.Ectopic IUDs are among the most serious complications.Ectopic IUDs are common in the myometrium and periuterine organs,and there are few reports of ectopic IUDs in the urinary bladder,especially in the anterior wall.CASE SUMMARY A 52-year-old woman was hospitalized due to a urinary bladder foreign body found via abdominal ultrasound and computed tomography(CT)examination.The patient had a 2-year history of recurrent abdominal distension and lower abdominal pain,accompanied by frequent urination,urgency,dysuria and other discomfort.Ultrasound examination revealed foreign bodies in the bladder cavity,with calculus on the surface of the foreign bodies.CT revealed a circular foreign body on the anterior wall of the urinary bladder,suggesting the possibility of an ectopic IUD.After laparoscopic exploration,an annular IUD was found in the anterior wall of urinary bladder,and an oval calculus with a diameter of approximately 2 cm was attached to the surface of the bladder cavity.The IUD and calculus were successfully and completely removed.The patient recovered well after surgery.CONCLUSION Abdominal ultrasound and CT are effective methods for detecting ectopic IUDs.The IUD is located in the urinary bladder and requires early surgical treatment.The choice of surgical method is determined by comprehensively considering the depth of the IUD in the bladder muscle layer,the situation of complicated calculus,the situation of intravesical inflammation and medical technology and equipment. 展开更多
关键词 intrauterine device ECTOPIC Anterior wall of the urinary bladder Calculus LAPAROSCOPE Case report
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Vaginal Testosterone Propionate with Misoprostol Prior to Removal of Intrauterine Devices in Postmenopausal Women
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作者 Jian SHEN Ning-xia SUN +1 位作者 Zong-rong TENG Yan LIU 《Journal of Reproduction and Contraception》 CAS 2013年第4期229-236,共8页
Objective To explore and investigate a new treatment of releasing the risks and pain in removing intrauterine devices (IUD) from postmenopausal women. Methods Totally 240 postmenopausal women who needed to remove IU... Objective To explore and investigate a new treatment of releasing the risks and pain in removing intrauterine devices (IUD) from postmenopausal women. Methods Totally 240 postmenopausal women who needed to remove IUD were randomly divided into 3 groups. Group A (n =80) were preoperatively treated with 20 g/L vaginal testosterone propionate cod liver oil ointment (1 g/d) over a 2-week span of period, and vaginal misoprostol (200 μg) was one-time used at 2-3 h before operation. Group B (n =80) were treated with oral estradiol valerate (3 mg/d) from 7 d before operation. Other 80 women (group C) were treated with vaginal cod liver oil ointment (1 g/d) over a 2-week span of period before the operation day. The degree of cervical relaxation, operational difficulty, blood loss volume, the length of operation time and visual analogue scales (VAS) were evaluated, also the serum estradiol, testosterone and endometrial thickness were measured before and after medication. Results The degree of cervical relaxation, operational difficulty, blood loss, the length of operation time and VAS in group A were significantly better than those group C (P〈0.01), whiles its blood loss volume was less than group B (P〈0.05) and there were no significant differences in serum estradiol, testosterone and endometrial thickness before and after medication. Conclusion Preoperative vaginal testosterone propionate combined with misoprostol would reduce the operational difficulties/risks and release the suffering of patients. The study may represent a safe and effective alternative to remove IUD in postmeno- pausal women. 展开更多
关键词 POSTMENOPAUSE intrauterine device (IUD) testosterone propionate MISOPROSTOL
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Postpartum Intrauterine Device: Use and Follow-Up of Users in the Maternity Ward of the Ratoma Communal Medical Center in Conakry, Guinea
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作者 Daniel W. A. Leno T. M. Millimouno +7 位作者 I. Conté A. Diallo A. F. M. Soumah I. Sylla H. M. Keita D. Lamah A. Delamou T. Sy 《Open Journal of Obstetrics and Gynecology》 2023年第10期1711-1721,共11页
Objective: The aim of this study was to describe the use of the postpartum intrauterine device in the maternity ward of the Ratoma communal medical center in Conakry. Methods: This was a descriptive cross-sectional st... Objective: The aim of this study was to describe the use of the postpartum intrauterine device in the maternity ward of the Ratoma communal medical center in Conakry. Methods: This was a descriptive cross-sectional study carried out between July 1<sup>st</sup> 2015 and June 30 2016, i.e. a duration of one year. Results: A total of 551 patients received advice on various contraceptive methods. Most of this advice was given in the post-partum period (40.2%) and during antenatal care (39.1%). Of the patients advised, 87 (15.8%) used the intrauterine device. The majority of users (93%) were married and uneducated (63.2%), and 39.1% were poor. The majority (56.3%) of intra-uterine devices were inserted in the immediate post-partum period. The majority of women had no adverse events either during the first six weeks (n = 57;65.5%) or at 3<sup>rd</sup> months (n = 75;86.2%) or 6<sup>th</sup> months (n = 76;87.4%) after IUD insertion. Most users remained complication-free throughout the follow-up period (n = 76;87.4% at 6<sup>th</sup> weeks and 3<sup>rd</sup> months, and n = 77;88.5% at 6<sup>th</sup> months). The continuation rate was 89.7% at 6 weeks and 3<sup>rd</sup> months, and 87.4% at 6<sup>th</sup> months after insertion. The majority of users (87.0%) were satisfied with the care they received. Conclusion: This study showed very few complications among intrauterine device users, and high continuation and satisfaction rates. The intrauterine device is a long-acting, effective, reversible and safe contraceptive that can be used by most women for birth spacing in Guinea, where women do not regularly visit health facilities. 展开更多
关键词 Postpartum intrauterine Device USE FOLLOW-UP Coronthie Communal Med-ical Center Conakry GUINEA
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非意愿妊娠女性人工流产后放置吉妮致美IUD效果
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作者 魏岚 韦玲 《中国计划生育学杂志》 2024年第1期142-145,共4页
目的:探讨非意愿妊娠女性人工流产后放置吉妮致美宫内节育器(IUD)效果.方法:以2021年7月-2022年7月在本院自愿要求人工流产术的未育女性213例,对实行流产后关爱干预,其中选择IUD避孕103例为观察组,未选择IUD避孕方法110例为对照组,问卷... 目的:探讨非意愿妊娠女性人工流产后放置吉妮致美宫内节育器(IUD)效果.方法:以2021年7月-2022年7月在本院自愿要求人工流产术的未育女性213例,对实行流产后关爱干预,其中选择IUD避孕103例为观察组,未选择IUD避孕方法110例为对照组,问卷调查比较两组干预前后对人工流产危害的知信行,比较流产后性生活恢复时间,随访1年非意愿妊娠及其妊娠原因、人工流产情况.结果:干预前后两组对人工流产危害性知识理论认知、态度信念、行为能力评分均提升(P<0.05),但两组间无差异;干预后观察组性生活恢复时间(3.7±0.1月)晚于对照组(3.2±0.9月),非意愿妊娠发生(8例,7.8%)低于对照组(24例,21.8%)(P<0.05),两组人工流产(0.9%、1.9%)发生无差异,观察组非意愿妊娠原因均为IUD脱落,对照组为避孕措施失败(11例,45.8%)和未避孕或避孕措施使用不正确(13例,54.2%).结论:吉妮致美IUD对降低人工流产后妇女非意愿妊娠有效,但需要重视IUD脱落率问题. 展开更多
关键词 人工流产后避孕 知信行 吉妮致美宫内节育器 非意愿妊娠 妊娠原因
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无痛人流术后放置曼月乐与活性γ-宫内节育器的避孕效果比较
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作者 张春红 孟庆霞 窦玉芝 《中国现代医学杂志》 CAS 2024年第12期90-94,共5页
目的 探讨无痛人流术后宫内放置曼月乐与活性γ-宫内节育器(γ-IUD)的临床效果比较。方法 选取2020年6月—2022年1月淄博市妇幼保健院收治的120例无痛人流手术后有避孕意愿的妇女作为研究对象。采用随机数字表法将其分为A、B组,每组60例... 目的 探讨无痛人流术后宫内放置曼月乐与活性γ-宫内节育器(γ-IUD)的临床效果比较。方法 选取2020年6月—2022年1月淄博市妇幼保健院收治的120例无痛人流手术后有避孕意愿的妇女作为研究对象。采用随机数字表法将其分为A、B组,每组60例。A组术后即刻宫内放置曼月乐避孕,B组术后即刻宫内放置活性γ-IUD避孕。对比两组妇女不同时间的宫内节育器续用情况、月经周期变化、性生活质量、并发症发生率差异。结果 术后6个月,A组与B组妇女的累积续用率分别为95.00%和98.33%,差异无统计学意义(χ^(2)=1.000,P=0.317)。术后12个月,A组与B组妇女的累积续用率为93.33%和96.67%,差异无统计学意义(χ^(2)=0.702,P=0.302)。A组与B组妇女术前、术后3个月的月经周期、行经时间、月经量及性欲、性唤起、性高潮、性心理、性行为、射精时间6个调查维度评分差值比较,差异均无统计学意义(P>0.05)。A组妇女术后总并发症发生率为23.33%,高于B组的8.33%(P <0.05)。结论 无痛人流术后宫内放置曼月乐与活性γ-IUD的宫内避孕效果、累积续用率、性生活情况差异不大,但是后者术后的并发症发生率更低,更推荐临床使用。 展开更多
关键词 无痛人流术 避孕 宫内节育 曼月乐 活性γ-IUD
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固定式与支架式宫内节育器的有效性、安全性和续用率比较
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作者 滕英 陈星 +6 位作者 岳茗肖 武冰雪 黄蔚 丁璟 秦明 车焱 张妍 《中国计划生育学杂志》 2024年第2期282-287,共6页
目的:观察固定式宫内节育器(IUD)在育龄女性中的安全性、有效性和续用情况。方法:以2022年1-6月使用国家免费IUD的育龄妇女为研究对象,随访置入后1、3个月的IUD避孕效果、不良反应和续用情况。多因素logistic回归分析有宫颈松弛、宫颈... 目的:观察固定式宫内节育器(IUD)在育龄女性中的安全性、有效性和续用情况。方法:以2022年1-6月使用国家免费IUD的育龄妇女为研究对象,随访置入后1、3个月的IUD避孕效果、不良反应和续用情况。多因素logistic回归分析有宫颈松弛、宫颈宽大、既往IUD脱落史、分娩后或人工流产后即时放置IUD等特征的“特殊人群”使用不同类型IUD对随访结局的影响。结果:纳入使用固定式或支架式IUD者分别为1060人和1589人,固定式IUD组中特殊人群535例(占50.5%),支架式式IUD组中特殊人群288例(占18.1%)。放置后3个月特殊人群中固定式IUD月经改变和白带异常的发生率较支架式IUD组低(16.8%比18.8%,3.0%比3.5%,均P<0.05),续用率较支架式IUD组高(97.7%比92.8%,P<0.001)。多因素logistic回归分析显示,在一般人群中,放置后1个月固定式IUD发生月经改变的风险相较于放置支架式IUD低(OR=0.62,95%CI0.45~0.85);放置后3个月固定式IUD组发生白带异常的风险均较低(一般人群OR=0.50,95%CI0.29~0.80;特殊人群OR=0.43,95%CI0.24~0.72);发生IUD脱落/异位的风险增加无统计学意义(一般人群OR=1.41,95%CI0.52~3.53;特殊人群OR=1.57,95%CI0.61~3.83)。结论:固定式IUD在白带异常和月经改变方面的表现较优于传统的支架式IUD;在一般人群和特殊人群中,固定式IUD均为一种安全有效的避孕方式。 展开更多
关键词 宫内节育器 月经改变 白带异常 腰腹疼痛
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不同非手术治疗方案在子宫腺肌病中的临床效果分析
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作者 王妍 哈春芳 +1 位作者 李譞 马远 《宁夏医学杂志》 CAS 2024年第2期128-131,共4页
目的探讨不同非手术治疗方案在子宫腺肌病中的临床效果。方法回顾性分析非手术治疗子宫腺肌病患者临床资料130例,根据主治医师及患者选择治疗方案分为A组(曼月乐组,50例)、B组[促性腺激素释放激素激动剂(GnRHa)+曼月乐组,50例]和C组(地... 目的探讨不同非手术治疗方案在子宫腺肌病中的临床效果。方法回顾性分析非手术治疗子宫腺肌病患者临床资料130例,根据主治医师及患者选择治疗方案分为A组(曼月乐组,50例)、B组[促性腺激素释放激素激动剂(GnRHa)+曼月乐组,50例]和C组(地诺孕素组,30例)。观察各组治疗前与治疗后不同时间的子宫体积变化、月经量、痛经症状缓解情况、不良反应发生率及复发率等,评估临床治疗效果。结果治疗后各时间点子宫体积B组均小于A组,A组均小于C组,差异有统计学意义(P<0.05)。治疗后各时间点VAS评分C组均小于A组,差异有统计学意义(P<0.05);治疗后3个月、6个月痛经VAS评分、PBAC评分B组小于A组,差异具有统计学意义(P<0.05);治疗后6个月月经量评分C组小于B组,差异有统计学意义(P<0.05);治疗后12个月、24个月PBAC评分C组小于A组,差异有统计学意义(P<0.05)。不规则流血发生情况C组与A组差异无统计学意义(P>0.05)。结论3组治疗均可以缓解临床症状,但以GnRHa+曼月乐效果最佳。 展开更多
关键词 子宫腺肌症 左炔诺孕酮宫内缓释系统 地诺孕素 促性腺激素抑制激素激动剂
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铜铝过渡线夹相控阵超声自动检测装置设计
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作者 余超 于奎才 +3 位作者 季昌国 韩哲文 王智春 张鹏鲲 《机械工程与自动化》 2024年第3期122-124,共3页
相控阵超声检测技术可直观有效地检测钎焊型铜铝过渡线夹,根据线夹结构研制了水浸式相控阵超声自动检测装置,该检测装置由主框架、水槽、运动模组、显示屏与控制装置、线夹夹持装置等部分组成,可完成对线夹的自动检测,既提高了检测效率... 相控阵超声检测技术可直观有效地检测钎焊型铜铝过渡线夹,根据线夹结构研制了水浸式相控阵超声自动检测装置,该检测装置由主框架、水槽、运动模组、显示屏与控制装置、线夹夹持装置等部分组成,可完成对线夹的自动检测,既提高了检测效率,又保证了采集数据的质量。经实验验证了检测装置的可行性,测试结果表明:该装置X、Y、Z轴的位移精度为0.05 mm,单个铜铝过渡夹具的检测速度为每件2 min,缺陷轮廓检测精度达到1 mm。 展开更多
关键词 铜铝过渡线夹 钎焊 相控阵超声检测 检测装置
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子宫颈癌放疗后宫内节育器取出23例分析
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作者 史连耀 马旭兰 +4 位作者 王丛 效小莉 张玉媛 朱嘉琦 付凤仙 《中国微创外科杂志》 CSCD 北大核心 2024年第4期313-316,共4页
目的探讨子宫颈癌放疗后宫内节育器(intrauterine device,IUD)取出的经验。方法2020年1月~2022年12月我科对23例子宫颈癌放疗后IUD在腹部超声引导宫腔镜下取出。对于阴道和(或)宫颈粘连,在腹部超声引导下,宫腔检查镜镜体喙部或弯钳钝性... 目的探讨子宫颈癌放疗后宫内节育器(intrauterine device,IUD)取出的经验。方法2020年1月~2022年12月我科对23例子宫颈癌放疗后IUD在腹部超声引导宫腔镜下取出。对于阴道和(或)宫颈粘连,在腹部超声引导下,宫腔检查镜镜体喙部或弯钳钝性分离粘连,若镜体喙部难以分离粘连进入宫腔,在超声引导下探针探入宫腔,逐渐扩张宫颈管至6号扩宫棒,再次置入宫腔检查镜进入宫腔;对于宫颈挛缩明显且坚韧,宫颈钳无法钳夹宫颈,1-0可吸收缝合线缝扎阴道顶端挛缩的宫颈前唇和(或)后唇,助手牢固牵拉固定宫颈。结果4例阴道部分粘连及宫颈挛缩,10例仅宫颈挛缩,余9例未见阴道粘连及宫颈挛缩。宫腔镜下见宫颈管粘连3例,子宫内膜息肉2例,黏膜下子宫肌瘤1例,宫腔积脓2例,IUD嵌顿2例,其余13例为正常宫腔形态。23例腹部超声引导宫腔镜成功完整取出IUD(圆形12例,宫形6例,V形2例,Y形1例,T形1例,伞形1例),手术时间(19.2±10.9)min,均无宫腔假道形成、子宫穿孔、脏器损伤、阴道大量出血、经尿道前列腺电切综合征、感染、栓塞、休克等并发症发生。23例术后随访2~24个月,中位数12个月,1例继续同步放化疗,3例继续后装放疗,1例继续化疗,2例靶向治疗(远处转移),余16例定期复查恢复良好,无腹痛、发热及阴道出血等并发症发生。结论子宫颈癌放疗后如果癌灶大小及部位不影响IUD取出,应尽早取出,腹部超声引导宫腔镜检查在宫颈癌放疗后IUD取出中具有一定的安全性及可行性。 展开更多
关键词 子宫颈癌 放疗 宫内节育器 宫腔镜
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宫腔镜取环术用于宫内节育环嵌顿的临床效果观察
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作者 孔冬梅 《中国现代药物应用》 2024年第9期44-47,共4页
目的探讨对宫内节育环嵌顿采用宫腔镜取环术治疗的临床效果。方法60例宫内节育环嵌顿患者,随机分为对照组和观察组,每组30例。对照组采用常规取环术治疗,观察组采用宫腔镜取环术治疗。比较两组手术指标以及取环情况、并发症发生率。结... 目的探讨对宫内节育环嵌顿采用宫腔镜取环术治疗的临床效果。方法60例宫内节育环嵌顿患者,随机分为对照组和观察组,每组30例。对照组采用常规取环术治疗,观察组采用宫腔镜取环术治疗。比较两组手术指标以及取环情况、并发症发生率。结果观察组手术时间(18.61±4.57)min、取环时间(8.12±1.53)min均短于对照组的(31.44±7.25)、(10.33±2.10)min,阴道出血量(9.76±2.10)ml少于对照组的(16.25±2.43)ml(P<0.05)。观察组取环成功率96.67%高于对照组的70.00%(P<0.05)。观察组并发症发生率6.67%低于对照组的36.67%(P<0.05)。结论对宫内节育环嵌顿患者采用宫腔镜取环术治疗较常规取环术操作简单、效率高,对患者损伤小,能够提高取环成功率,可降低术后并发症发生风险,值得推广。 展开更多
关键词 宫腔镜取环术 常规取环术 节育环嵌顿 宫内节育器 并发症
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未育女性人工流产术后即时放置宫内节育器的影响因素研究
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作者 王聘清 夏菁 张英敏 《中国医药导报》 CAS 2024年第11期43-46,共4页
目的探讨宫内节育器(IUD)即时放置于未育女性人工流产术后的影响因素。方法回顾性研究2021年5月至2023年3月于扬州大学附属淮安市妇幼保健院行人工流产术的未育女性80例的临床资料,根据人工流产术后患者是否即时放置IUD设为放置IUD组(50... 目的探讨宫内节育器(IUD)即时放置于未育女性人工流产术后的影响因素。方法回顾性研究2021年5月至2023年3月于扬州大学附属淮安市妇幼保健院行人工流产术的未育女性80例的临床资料,根据人工流产术后患者是否即时放置IUD设为放置IUD组(50例)和未放置IUD组(30例)。比较两组一般资料,采用多因素logistic回归分析明确未育女性人工流产术后即时放置IUD的影响因素。结果放置IUD组待业、性生活频率≥4次/月、流产次数2~3次、近2年有生育需求、知道人工流产术后可立即放置IUD者占比高于未放置IUD组(P<0.05)。多因素logistic回归分析显示,待业(OR=9.487)、性生活频率≥4次/月(OR=8.975)、流产次数2~3次(OR=10.568)、近2年有生育需求(OR=9.154)、知道人工流产术后可立即放置IUD(OR=12.568)是未育女性人工流产术后IUD即时放置的影响因素(P<0.05)。结论未育女性人工流产术后即时放置IUD的影响因素为待业、性生活频率≥4次/月、流产次数2~3次、近2年有生育需求、知道人工流产术后可立即放置IUD。因此,临床应加强宣教IUD相关知识,全面推广人工流产术后关爱服务。 展开更多
关键词 未育女性 人工流产术 宫内节育器 影响因素
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住院妇科疾病患者中宫内节育器应用情况分析
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作者 彭博 叶兵 +2 位作者 胡伟 陈龙 赵沅幸子 《中国计划生育学杂志》 2024年第5期1017-1021,共5页
目的:分析广东省2017-2022年宫内节育器(IUD)在妇科疾病辅助治疗中的应用现状,为进一步扩大其在临床疾病辅助治疗中的应用提供参考依据。方法:对2017年1月-2022年12月患有妇科疾病且放置IUD治疗者住院病案首页的信息进行统计分析,分析... 目的:分析广东省2017-2022年宫内节育器(IUD)在妇科疾病辅助治疗中的应用现状,为进一步扩大其在临床疾病辅助治疗中的应用提供参考依据。方法:对2017年1月-2022年12月患有妇科疾病且放置IUD治疗者住院病案首页的信息进行统计分析,分析不同年龄段或不同妇科疾病、不同等级和类别医疗机构及不同年份放置IUD情况。结果:2017-2022年间住院妇科疾病患者中放置IUD治疗的人数逐年递增,2022年患者年龄从6年前(35.3±7.4)岁提高至(38.3±6.5)岁,人数也较6年前增加了141.8%;入住的医疗机构主要为三级综合医院,不同等级医疗机构IUD使用率比较差异有统计学意义(P<0.05);IUD在子宫内膜息肉、子宫内膜增生和异常子宫出血3类疾病中的使用呈上升趋势。结论:住院治疗妇科类疾病并以IUD作为辅助治疗措施的患者人数在逐年递增,主要集中在子宫内膜息肉、子宫内膜增生和异常子宫出血等疾病。 展开更多
关键词 宫内节育器 妇科疾病 住院患者 辅助治疗
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妇科计划生育中放置宫内节育器手术的风险性分析
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作者 吴志丽 《中国医药指南》 2024年第4期111-113,共3页
目的 针对妇科计划生育开展过程中,放置宫内节育器手术存在的风险性进行分析与研究。方法 选取2019年1月至2022年12月在莆田市荔城区妇幼保健所实施放置宫内节育器手术的女性共60例展开此次研究,结合随机方式分组,分成对照组和试验组,... 目的 针对妇科计划生育开展过程中,放置宫内节育器手术存在的风险性进行分析与研究。方法 选取2019年1月至2022年12月在莆田市荔城区妇幼保健所实施放置宫内节育器手术的女性共60例展开此次研究,结合随机方式分组,分成对照组和试验组,各30例,在进行手术过程中,对照组运用常规手术管理,试验组运用风险管理,观察两组风险发生情况。结果 术后,对照组风险事件实际发生率26.67%,试验组风险事件实际发生率6.67%,两组对比,试验组风险事件实际发生率更低(P<0.05)。对照组依从性70.00%,试验组依从性93.33%,两组对比,试验组依从性更高(P<0.05)。对照组手术满意度评分(67.34±3.75)分,试验组手术满意度评分(83.61±3.07)分,两组对比,试验组获得的手术满意度评分明显更高(t=18.3878,P<0.0001)。结论 妇科计划生育开展时,实施放置宫内节育器手术,往往会存在一定风险性,对于出现的风险,应进行认真总结分析,加强风险控制,对于出现的风险采取有效控制措施,尽量使风险发生率得以降低,确保获得更好手术效果。 展开更多
关键词 计划生育 宫内节育器 风险性
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