Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of astrocytes.These events a...Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of astrocytes.These events are significantly slower than the excitatory postsynaptic currents.Parameters of slow inward currents are determined by seve ral factors including the mechanisms of astrocytic activation and glutamate release,as well as the diffusion pathways from the release site towards the extra synaptic recepto rs.Astrocytes are stimulated by neuronal network activity,which in turn excite neurons,forming an astrocyte-neuron feedback loop.Mostly as a consequence of brain edema,astrocytic swelling can also induce slow inward currents under pathological conditions.There is a growing body of evidence on the roles of slow inward currents on a single neuron or local network level.These events often occur in synchro ny on neurons located in the same astrocytic domain.Besides synchronization of neuronal excitability,slow inward currents also set synaptic strength via eliciting timing-dependent synaptic plasticity.In addition,slow inward currents are also subject to non-synaptic plasticity triggered by long-la sting stimulation of the excitatory inputs.Of note,there might be important regionspecific differences in the roles and actions triggering slow inward currents.In greater networks,the pathophysiological roles of slow inward currents can be better understood than physiological ones.Slow inward currents are identified in the pathophysiological background of autism,as slow inward currents drive early hypersynchrony of the neural networks.Slow inward currents are significant contributors to paroxysmal depolarizational shifts/interictal spikes.These events are related to epilepsy,but also found in Alzheimer's disease,Parkinson's disease,and stroke,leading to the decline of cognitive functions.Events with features overlapping with slow inward currents(excitatory,N-methyl-Daspartate-receptor mediated currents with astrocytic contribution) as ischemic currents and spreading depolarization also have a well-known pathophysiological role in worsening consequences of stroke,traumatic brain injury,or epilepsy.One might assume that slow inward currents occurring with low frequency under physiological conditions might contribute to synaptic plasticity and memory formation.However,to state this,more experimental evidence from greater neuronal networks or the level of the individual is needed.In this review,I aimed to summarize findings on slow inward currents and to speculate on the potential functions of it.展开更多
The inward particle transport is associated with the formation of peaked density profiles,which contributes to improve the fusion rate and the realization of steady-state discharge.The active control of inward particl...The inward particle transport is associated with the formation of peaked density profiles,which contributes to improve the fusion rate and the realization of steady-state discharge.The active control of inward particle transport is considered as one of the most critical issues of magnetic confinement fusion.Recently,it is realized preliminarily by adding a biased endplate in the Peking University Plasma Test(PPT)device.The results reveal that the inward particle flux increases with the bias voltage of the endplate.It is also found that the profile of radial electric field(Er)shear is flattened by the increased bias voltage.Radial velocity fluctuations affect the inward particle more than density fluctuations,and the frequency of the dominant mode driving inward particle flux increases with the biased voltage applied to the endplate.The experimental results in the PPT device provide a method to actively control the inward particle flux using a biased endplate and enrich the understanding of the relationship between E_(r)×B shear and turbulence transport.展开更多
This paper is an attempt to investigate systematically fixed points of weakly inward maps by using some basic results from differential equations in Banach spaces. By investigating the Poincare operators for such diff...This paper is an attempt to investigate systematically fixed points of weakly inward maps by using some basic results from differential equations in Banach spaces. By investigating the Poincare operators for such differential equations, we establish a fixed point index theory for two classes of weakly inward maps.展开更多
We report multi-spacecraft observations of ULF waves from Van Allen Probes(RBSP), Magnetospheric Multiscale(MMS), Time History of Events and Macroscale Interactions during Substorm(THEMIS), and Geostationary Operation...We report multi-spacecraft observations of ULF waves from Van Allen Probes(RBSP), Magnetospheric Multiscale(MMS), Time History of Events and Macroscale Interactions during Substorm(THEMIS), and Geostationary Operational Environmental Satellites(GOES).On August 31, 2015, global-scale poloidal waves were observed in data from RBSP-B, GOES and THEMIS from L=4 to L=8 over a wide range of magnetic local time(MLT). The polarization states varied towards purely poloidal polarity. In two consecutive orbits over 18 hours, RBSP-A and RBSP-B recorded gradual variation of the polarization states of the poloidal waves; the ratio(|B_a|/|B_r|) decreased from 0.82 to 0.13. After the variation of polarization states, the poloidal ULF waves became very purely poloidal waves, localized in both L and MLT. We identify the poloidal wave as second harmonic mode with a large azimuthal wave number(m) of –232. From RBSP particle measurements we find evidence that the high-m poloidal waves during the polarization variations were powered by inward radial gradients and bump-on-tail ion distributions through the N=1 drift-bounce resonance. Most of the time, the dominant free energy source was inward radial gradients, compared with the positive gradient in the energy distribution of the bump-on-tail ion distributions.展开更多
Impurity accumulation is studied for neutral beam-heated discharges after hydrogen multi-pellet injection in Large Helical Device （LHD）. Iron density profiles are derived from radial profiles of EUV line emissions o...Impurity accumulation is studied for neutral beam-heated discharges after hydrogen multi-pellet injection in Large Helical Device （LHD）. Iron density profiles are derived from radial profiles of EUV line emissions of FeXV-XXIV with the help of the collisional-radiative model. A peaked density profile of Fe2a＋ is simulated by using one-dimensional impurity transport code. The result indicates a large inward velocity of -6 m/s at the impurity accumulation phase. However, the discharge is not entirely affected by the impurity accumulation, since the concentration of iron impurity, estimated to be 3.3x10-5 to the electron density, is considerably small. On the other hand, a flat profile is observed for the carbon density of C6＋, which is derived from the Zeff profile, indicating a small inward velocity of -1 m/s. These results suggest atomic number dependence in the impurity accumulation of LHD, which is similar to the tokamak result.展开更多
In this paper, we discuss the concept of fixed point curve for linear interpolations of weakly inward contractions and establish necessary condition for a nonex- pansive mapping to have approximate fixed point property.
In this paper we define a fixed point index theory for locally Lip., completely continuous and weakly inward mappings defined on closed convex sets in general Banach spaces where no other artificial conditions are imp...In this paper we define a fixed point index theory for locally Lip., completely continuous and weakly inward mappings defined on closed convex sets in general Banach spaces where no other artificial conditions are imposed. This makes ns to deal with these kinds of mappings more easily. As obvious applications, some results in [3],[5],[7],[9],[10] are deepened and extended.展开更多
基金funded by the National Research Developm ent and Innovation Office (NKFIH-K1468 73) (to BP)。
文摘Slow inward currents are known as neuronal excitatory currents mediated by glutamate release and activation of neuronal extra synaptic N-met hyl-D-aspartate receptors with the contribution of astrocytes.These events are significantly slower than the excitatory postsynaptic currents.Parameters of slow inward currents are determined by seve ral factors including the mechanisms of astrocytic activation and glutamate release,as well as the diffusion pathways from the release site towards the extra synaptic recepto rs.Astrocytes are stimulated by neuronal network activity,which in turn excite neurons,forming an astrocyte-neuron feedback loop.Mostly as a consequence of brain edema,astrocytic swelling can also induce slow inward currents under pathological conditions.There is a growing body of evidence on the roles of slow inward currents on a single neuron or local network level.These events often occur in synchro ny on neurons located in the same astrocytic domain.Besides synchronization of neuronal excitability,slow inward currents also set synaptic strength via eliciting timing-dependent synaptic plasticity.In addition,slow inward currents are also subject to non-synaptic plasticity triggered by long-la sting stimulation of the excitatory inputs.Of note,there might be important regionspecific differences in the roles and actions triggering slow inward currents.In greater networks,the pathophysiological roles of slow inward currents can be better understood than physiological ones.Slow inward currents are identified in the pathophysiological background of autism,as slow inward currents drive early hypersynchrony of the neural networks.Slow inward currents are significant contributors to paroxysmal depolarizational shifts/interictal spikes.These events are related to epilepsy,but also found in Alzheimer's disease,Parkinson's disease,and stroke,leading to the decline of cognitive functions.Events with features overlapping with slow inward currents(excitatory,N-methyl-Daspartate-receptor mediated currents with astrocytic contribution) as ischemic currents and spreading depolarization also have a well-known pathophysiological role in worsening consequences of stroke,traumatic brain injury,or epilepsy.One might assume that slow inward currents occurring with low frequency under physiological conditions might contribute to synaptic plasticity and memory formation.However,to state this,more experimental evidence from greater neuronal networks or the level of the individual is needed.In this review,I aimed to summarize findings on slow inward currents and to speculate on the potential functions of it.
基金supported by the National MCF Energy R&D Program of China(No.2018YFE0303100)National Natural Science Foundation of China(No.11975038)。
文摘The inward particle transport is associated with the formation of peaked density profiles,which contributes to improve the fusion rate and the realization of steady-state discharge.The active control of inward particle transport is considered as one of the most critical issues of magnetic confinement fusion.Recently,it is realized preliminarily by adding a biased endplate in the Peking University Plasma Test(PPT)device.The results reveal that the inward particle flux increases with the bias voltage of the endplate.It is also found that the profile of radial electric field(Er)shear is flattened by the increased bias voltage.Radial velocity fluctuations affect the inward particle more than density fluctuations,and the frequency of the dominant mode driving inward particle flux increases with the biased voltage applied to the endplate.The experimental results in the PPT device provide a method to actively control the inward particle flux using a biased endplate and enrich the understanding of the relationship between E_(r)×B shear and turbulence transport.
文摘This paper is an attempt to investigate systematically fixed points of weakly inward maps by using some basic results from differential equations in Banach spaces. By investigating the Poincare operators for such differential equations, we establish a fixed point index theory for two classes of weakly inward maps.
基金supported by NNSFC grants 41574161,41731070,and 41574159the Strategic Pionner Program on Space Science,Chinese Academy of Sciences,grants XDA15052500 and XDA15350201
文摘We report multi-spacecraft observations of ULF waves from Van Allen Probes(RBSP), Magnetospheric Multiscale(MMS), Time History of Events and Macroscale Interactions during Substorm(THEMIS), and Geostationary Operational Environmental Satellites(GOES).On August 31, 2015, global-scale poloidal waves were observed in data from RBSP-B, GOES and THEMIS from L=4 to L=8 over a wide range of magnetic local time(MLT). The polarization states varied towards purely poloidal polarity. In two consecutive orbits over 18 hours, RBSP-A and RBSP-B recorded gradual variation of the polarization states of the poloidal waves; the ratio(|B_a|/|B_r|) decreased from 0.82 to 0.13. After the variation of polarization states, the poloidal ULF waves became very purely poloidal waves, localized in both L and MLT. We identify the poloidal wave as second harmonic mode with a large azimuthal wave number(m) of –232. From RBSP particle measurements we find evidence that the high-m poloidal waves during the polarization variations were powered by inward radial gradients and bump-on-tail ion distributions through the N=1 drift-bounce resonance. Most of the time, the dominant free energy source was inward radial gradients, compared with the positive gradient in the energy distribution of the bump-on-tail ion distributions.
基金support by LHD project (NIFS11ULPP010)partly supported by the JSPS-NRF-NSFC A3 Foresight Program in the field of Plasma Physics
文摘Impurity accumulation is studied for neutral beam-heated discharges after hydrogen multi-pellet injection in Large Helical Device （LHD）. Iron density profiles are derived from radial profiles of EUV line emissions of FeXV-XXIV with the help of the collisional-radiative model. A peaked density profile of Fe2a＋ is simulated by using one-dimensional impurity transport code. The result indicates a large inward velocity of -6 m/s at the impurity accumulation phase. However, the discharge is not entirely affected by the impurity accumulation, since the concentration of iron impurity, estimated to be 3.3x10-5 to the electron density, is considerably small. On the other hand, a flat profile is observed for the carbon density of C6＋, which is derived from the Zeff profile, indicating a small inward velocity of -1 m/s. These results suggest atomic number dependence in the impurity accumulation of LHD, which is similar to the tokamak result.
文摘In this paper, we discuss the concept of fixed point curve for linear interpolations of weakly inward contractions and establish necessary condition for a nonex- pansive mapping to have approximate fixed point property.
文摘In this paper we define a fixed point index theory for locally Lip., completely continuous and weakly inward mappings defined on closed convex sets in general Banach spaces where no other artificial conditions are imposed. This makes ns to deal with these kinds of mappings more easily. As obvious applications, some results in [3],[5],[7],[9],[10] are deepened and extended.
