The reaction between perfluoroalkanesulfinate salts(1)[R_fSO_2M R_f=a,Cl(CF_2)_4;b,Cl(CF_2)_6;c,Cl(CF_2)8;d,n-C_6F_(13);e,n-C_8F_(17);M-Na;K; Hg(I)]and iodine monochloride in dichloromethane at low temperature(e.g. -3...The reaction between perfluoroalkanesulfinate salts(1)[R_fSO_2M R_f=a,Cl(CF_2)_4;b,Cl(CF_2)_6;c,Cl(CF_2)8;d,n-C_6F_(13);e,n-C_8F_(17);M-Na;K; Hg(I)]and iodine monochloride in dichloromethane at low temperature(e.g. -30--50℃)resulted in the formation of the corresponding perfluoroalkane- sulfonyl iodides(2),which were identified by their 19_F NMR spectra.The perfluoroalkanesulfonyl iodides generated in situ reacted smoothly with olefins to forum 1:1 adducts with good yields.Thus,these reactions provide another method for the synthesis of the very unstable perfluoroalkanesulfonyl iodide.展开更多
Photoredox-catalyzed hydrodifluoromethylation of alkenes has become an effective method to introduce difluoromethyl group into organic molecules.As the reported methods involve either photocatalysts or superstoichiome...Photoredox-catalyzed hydrodifluoromethylation of alkenes has become an effective method to introduce difluoromethyl group into organic molecules.As the reported methods involve either photocatalysts or superstoichiometric amounts of additives,we herein describe a simple alternative without using photocatalyst or additive for the hydrodifluoromethylation of alkenes,through photoactivation of difluoromethyltriphenylphosphonium iodide salt.Mechanistic studies shed light on how the transformation takes place.展开更多
文摘The reaction between perfluoroalkanesulfinate salts(1)[R_fSO_2M R_f=a,Cl(CF_2)_4;b,Cl(CF_2)_6;c,Cl(CF_2)8;d,n-C_6F_(13);e,n-C_8F_(17);M-Na;K; Hg(I)]and iodine monochloride in dichloromethane at low temperature(e.g. -30--50℃)resulted in the formation of the corresponding perfluoroalkane- sulfonyl iodides(2),which were identified by their 19_F NMR spectra.The perfluoroalkanesulfonyl iodides generated in situ reacted smoothly with olefins to forum 1:1 adducts with good yields.Thus,these reactions provide another method for the synthesis of the very unstable perfluoroalkanesulfonyl iodide.
基金financial support from the National Natural Science Foundation of China(Nos.22001248 and 22173103)the Fundamental Research Funds for the Central Universities and the University of the Chinese Academy of Sciences。
文摘Photoredox-catalyzed hydrodifluoromethylation of alkenes has become an effective method to introduce difluoromethyl group into organic molecules.As the reported methods involve either photocatalysts or superstoichiometric amounts of additives,we herein describe a simple alternative without using photocatalyst or additive for the hydrodifluoromethylation of alkenes,through photoactivation of difluoromethyltriphenylphosphonium iodide salt.Mechanistic studies shed light on how the transformation takes place.
