We describe an iron-catalyzed amide bond formation from readily available carboxylic acids and isocyanates.This method utilizes an abundant and biocompatible iron catalyst and easily accessible starting materials,gene...We describe an iron-catalyzed amide bond formation from readily available carboxylic acids and isocyanates.This method utilizes an abundant and biocompatible iron catalyst and easily accessible starting materials,generates CO_(2) as the only byproduct,and features broad substrate scopes with good functional group compatibility.Therefore,it provides a cost-effective and practical protocol to access a diverse variety of amides.展开更多
基金the National Natural Science Foundation of China(2207118522271224)Wuhan University startup funding for financial support.
文摘We describe an iron-catalyzed amide bond formation from readily available carboxylic acids and isocyanates.This method utilizes an abundant and biocompatible iron catalyst and easily accessible starting materials,generates CO_(2) as the only byproduct,and features broad substrate scopes with good functional group compatibility.Therefore,it provides a cost-effective and practical protocol to access a diverse variety of amides.
