The title compounds（Z）-3-（2-（3-chloropyridin-2-yl）hydrazono）indolin-2-one（A） and 7-bromo-（Z）-3-（（4-pyridinyl）carboxlichydrazono）-2-indolinone（B） have been synthesized and structurally determined by ele...The title compounds（Z）-3-（2-（3-chloropyridin-2-yl）hydrazono）indolin-2-one（A） and 7-bromo-（Z）-3-（（4-pyridinyl）carboxlichydrazono）-2-indolinone（B） have been synthesized and structurally determined by elemental analysis and single-crystal X-ray diffraction studies.Compound A（C13H8ClN4O） belongs to the orthorhombic crystal system,space group Pca21 with a = 20.799（4）,b = 4.9312（10）,c = 11.764（2）,V = 1206.6（4）3,Mr = 271.68,Dc = 1.496 g/cm3,μ = 0.313 mm-1,F（000） = 556,Z = 4,the final R = 0.0346 and wR = 0.0831 for 2683 observed reflections with I 2σ（I）.Compound B（C14H9BrN4O2） belongs to the triclinic crystal system,space group P1 with a = 6.6834（13）,b = 7.0727（14）,c = 14.285（3）,α = 95.56（3）,β = 99.00（3）,γ = 102.95（3）°,V = 643.8（2）3,Mr = 345.16,Dc = 1.780 g/cm3,μ = 3.203 mm-1,F（000） = 344,Z = 2,the final R = 0.0487 and wR = 0.1167 for 2334 observed reflections with I 2σ（I）.The preliminary herbicidal bioassay reveals that compounds A and B have some inhibition both in vivo and in vitro against AHAS.展开更多
Two novel compounds 1-（4-fluorobenzyl）-4-chloro-（Z）-3-benzoylhydrazono-2-indolinone（1） and 1-（4-methoxybenzyl）-（Z）-3-benzoylhydrazono-2-indolinone（2） were synthesized and their crystal structures were dete...Two novel compounds 1-（4-fluorobenzyl）-4-chloro-（Z）-3-benzoylhydrazono-2-indolinone（1） and 1-（4-methoxybenzyl）-（Z）-3-benzoylhydrazono-2-indolinone（2） were synthesized and their crystal structures were determined by single-crystal X-ray diffraction.Compound 1（C22H15ClFN3O2） crystallized in the triclinic system,space group P1·with a=0.94198（19） nm,b=1.4339（3） nm,c=1.5018（3） nm,α=101.58（3）°,β=102.96（3）°,γ=102.73°,V=1.8602（6） nm3,Mr=407.82,Dc=1.456 g/cm3,μ=0.240 mm-1,F（000）=840,Z=4,R1=0.0442 and wR2=0.1064.Compound 2（C23H19N3O3） crystallized in the triclinic system,space group P1·with a=1.0022（2） nm,b=1.0192（2） nm,c=1.0461（2） nm,α=99.86（3）°,β=117.30（3）°,γ=94.13（3）°,V=0.9215（3） nm3,Mr=385.41,Dc=1.389 g/cm3,μ=0.094 mm-1,F（000）=404,Z=2,R1=0.0403 and wR2=0.1142.The preliminary herbicidal activities of the two compounds were also evaluated.展开更多
An efficient asymmetric alkenylation between 3-vinylindoles and isatin derivatives was developed under catalysis of a chiral copper complex.A series of optically active 3-alkenyl-3-substituted oxindoles were obtained ...An efficient asymmetric alkenylation between 3-vinylindoles and isatin derivatives was developed under catalysis of a chiral copper complex.A series of optically active 3-alkenyl-3-substituted oxindoles were obtained in excellent yields and stereoselectivities.The reaction mechanism was proposed and supported by DFT calculation.展开更多
基金supported by the China-Australia linkage grant form National Natural Science Foundation (NSFC#20911120022)National 973 program (2010CB126103)
文摘The title compounds（Z）-3-（2-（3-chloropyridin-2-yl）hydrazono）indolin-2-one（A） and 7-bromo-（Z）-3-（（4-pyridinyl）carboxlichydrazono）-2-indolinone（B） have been synthesized and structurally determined by elemental analysis and single-crystal X-ray diffraction studies.Compound A（C13H8ClN4O） belongs to the orthorhombic crystal system,space group Pca21 with a = 20.799（4）,b = 4.9312（10）,c = 11.764（2）,V = 1206.6（4）3,Mr = 271.68,Dc = 1.496 g/cm3,μ = 0.313 mm-1,F（000） = 556,Z = 4,the final R = 0.0346 and wR = 0.0831 for 2683 observed reflections with I 2σ（I）.Compound B（C14H9BrN4O2） belongs to the triclinic crystal system,space group P1 with a = 6.6834（13）,b = 7.0727（14）,c = 14.285（3）,α = 95.56（3）,β = 99.00（3）,γ = 102.95（3）°,V = 643.8（2）3,Mr = 345.16,Dc = 1.780 g/cm3,μ = 3.203 mm-1,F（000） = 344,Z = 2,the final R = 0.0487 and wR = 0.1167 for 2334 observed reflections with I 2σ（I）.The preliminary herbicidal bioassay reveals that compounds A and B have some inhibition both in vivo and in vitro against AHAS.
基金Supported by the China-Australia Linkage Grant form of National Natural Science Foundation,China(No.20911120022)the National Key Technology Research and Development Program of China(No.2011BAE06B05-3)
文摘Two novel compounds 1-（4-fluorobenzyl）-4-chloro-（Z）-3-benzoylhydrazono-2-indolinone（1） and 1-（4-methoxybenzyl）-（Z）-3-benzoylhydrazono-2-indolinone（2） were synthesized and their crystal structures were determined by single-crystal X-ray diffraction.Compound 1（C22H15ClFN3O2） crystallized in the triclinic system,space group P1·with a=0.94198（19） nm,b=1.4339（3） nm,c=1.5018（3） nm,α=101.58（3）°,β=102.96（3）°,γ=102.73°,V=1.8602（6） nm3,Mr=407.82,Dc=1.456 g/cm3,μ=0.240 mm-1,F（000）=840,Z=4,R1=0.0442 and wR2=0.1064.Compound 2（C23H19N3O3） crystallized in the triclinic system,space group P1·with a=1.0022（2） nm,b=1.0192（2） nm,c=1.0461（2） nm,α=99.86（3）°,β=117.30（3）°,γ=94.13（3）°,V=0.9215（3） nm3,Mr=385.41,Dc=1.389 g/cm3,μ=0.094 mm-1,F（000）=404,Z=2,R1=0.0403 and wR2=0.1142.The preliminary herbicidal activities of the two compounds were also evaluated.
基金support from the National Natural Science Foundation of China(No.21772185)supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB20000000).
文摘An efficient asymmetric alkenylation between 3-vinylindoles and isatin derivatives was developed under catalysis of a chiral copper complex.A series of optically active 3-alkenyl-3-substituted oxindoles were obtained in excellent yields and stereoselectivities.The reaction mechanism was proposed and supported by DFT calculation.
