BACKGROUND Bell’s palsy is an idiopathic facial palsy with an unknown cause,and 75%of patients heal spontaneously.However,the other 25%of patients continue experiencing mild or severe disabilities,resulting in a redu...BACKGROUND Bell’s palsy is an idiopathic facial palsy with an unknown cause,and 75%of patients heal spontaneously.However,the other 25%of patients continue experiencing mild or severe disabilities,resulting in a reduced quality of life.Currently,various treatment methods have been developed to treat this disease.However,there is controversy regarding their effectiveness,and new alternative treatments are needed.CASE SUMMARY The patient suffered from left-sided facial paralysis due to Bell’s palsy for 7 years.The patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for treatment.After follow-up for 32 mo,the paralysis was cured,and there was no recurrence.CONCLUSION Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell’s palsy who do not spontaneously recover.展开更多
Introduction: Bell’s palsy is an uncommon adverse effect of the COVID-19 vaccine that has been reported in clinical trials. Even though a few studies have linked the vaccination to Bell’s palsy, the actual mechanism...Introduction: Bell’s palsy is an uncommon adverse effect of the COVID-19 vaccine that has been reported in clinical trials. Even though a few studies have linked the vaccination to Bell’s palsy, the actual mechanism is uncertain. Objectives: To describe the demographic data and COVID-19 vaccines-related data with Bell’s palsy in a tertiary centre of Malaysia, Hospital Kuala Lumpur. Methods: A retrospective cross-sectional study was observed among vaccinated recipients who developed Bell’s palsy within 60 days and sought treatment in the Otorhinolaryngology Department Hospital Kuala Lumpur, Malaysia between 1<sup>st</sup> May 2021 and 30<sup>th</sup> November 2021. The demographic data, clinical history, and vaccination history were collected from clinical records. The facial paralysis was graded according to the House-Brackmann grading system. Results: A total of 26 patients with a mean age was 38.5 years;higher incidence in younger age, below 60 years old (n = 24), specifically 18 - 30 years old (n = 11). We observed an equal number in relation to gender and onset (after the first or second dose) of facial palsy. Predominantly were Malay (n = 21) and only 6 patients had comorbidities. We found there was no difference in regard to the type of vaccine among Bell’s palsy patients;Pfizer (n = 9), followed by Sinovac (n = 9) and AstraZeneca (n = 8). Conclusion: Bell’s palsy was found to be a possible adverse event of the COVID-19 vaccine. Younger groups were noted as susceptible to this rare adverse effect. However, the benefits of vaccination outweigh the risk of Bell’s palsy, which has a good prognosis. More research with larger samples is needed to determine the true relationship between vaccination and Bell’s palsy.展开更多
J. S. Bell’s well-known proofs of inequalities (and related work) are shown to be invalidated by two counter-arguments (-examples) that are based on Einstein-local propositions: Bell-type inequalities of Einstein-Pod...J. S. Bell’s well-known proofs of inequalities (and related work) are shown to be invalidated by two counter-arguments (-examples) that are based on Einstein-local propositions: Bell-type inequalities of Einstein-Podolsky-Rosen experiments must include, as virtually all physical theories do, elements of physical reality and their mathematical representations that relate to continua as opposed to exclusively finite numbers. Furthermore, Bell-type inequalities must be valid for all possible experimental geometries that lead to the quantum result. Based on these propositions, violations of Bell-type inequalities are demonstrated without violating Einstein locality, without conspiracy type theories and even for the case that all known “loopholes” are closed.展开更多
We report a case of a rare sporadic Vestibular Schwannoma of a 9-month-old girl who had a right-sided lower motor type facial nerve palsy. The patient was initially diagnosed with Bell’s palsy and received steroid tr...We report a case of a rare sporadic Vestibular Schwannoma of a 9-month-old girl who had a right-sided lower motor type facial nerve palsy. The patient was initially diagnosed with Bell’s palsy and received steroid treatment accordingly, two months later the patient’s condition deteriorated, and further evaluation of CT and MRI brain was conducted that showed a mass lesion in the posterior fossa causing compression on the facial nerve. Misdiagnosis of facial nerve paralysis is common among children due to multiple related etiologies and varying rates of incidence in comparison to adults. The authors hope to address this issue in this report. Background: Facial nerve paralysis has been a matter of concern for many researchers to understand its nature, causes and presentation according to different age groups. In adults, Bell’s palsy (BP), the idiopathic form of facial nerve paralysis, is more common compared to children where most cases are due to secondary etiologies. Therefore, pediatricians are in an important position to identify these patients early in order to launch the most effective diagnostic and treatment approaches.展开更多
OBJECTIVE： To assess the efficacy of acupuncture combined with vitamin B12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell＇s palsy. DATA RETRIEVAL： A computer-based o...OBJECTIVE： To assess the efficacy of acupuncture combined with vitamin B12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell＇s palsy. DATA RETRIEVAL： A computer-based online retrieval of Medline, Web of Science, CNKI, CBM databases until April 2014 was performed for relevant trials, using the key words ＂Bell＇s palsy or idiopathic facial palsy or facial palsy＂ and＂acupuncture or vitamin B12 or methylcobalamin＂. STUDY SELECTION： All randomized controlled trials that compared acupuncture with acupuncture combined with vitamin B12 in patients with Bell＇s palsy were included in the me- ta-analysis. The initial treatment lasted for at least 4 weeks. The outcomes of incomplete facial recovery were monitored. The scoring index varied and the definition of healing was consistent. The combined effect size was calculated by using relative risk （RR） with 95% confidence interval （C/） using the fixed effect model of Review Manager. MAIN OUTCOME MEASURES： Incomplete recovery rates were chosen as the primary outcome. RESULTS： Five studies involving 344 patients were included in the final analysis. Results showed that the incomplete recovery rate of Bell＇s palsy patients was 44.50% in the acupuncture combined with vitamin B12 group but 62.57% in the acupuncture alone group. The major acupoints were Taiyang （EX-HN5）, Jiache （ST6）, Dicang （ST4） and Sibai （ST2）. The combined effect size showed that acupuncture combined with vitamin B12 was better than acupuncture alone for the treatment of Belrs palsy （RR = 0.71, 95%CI： 0.58-0.87; P = 0.001）, this result held true when 8 patients lost to follow up in one study were included into the analyses （RR = 0.70, 95%CI： 0.58-0.86; P = 0.0005）. In the subgroup analyses, the therapeutic effect in patients of the electroacupuncture subgroup was better than in the non-electroacupuncture subgroup （P = 0.024）. There was no significant dif- ference in the incomplete recovery rate by subgroup analysis on drug types and treatment period. Most of the included studies were moderate or low quality, and bias existed. CONCLUSION： In patients with Bell＇s palsy, acupuncture combined with vitamin 812 can reduce the risk of incomplete recovery compared with acupuncture alone in our meta-analysis. Because of study bias and methodological limitations, this conclusion is uncertain and the clinical appli- cation of acupuncture combined with vitamin B12 requires further exploration.展开更多
T.S.Eliot was a leader of the Modernist movement in poetry.His early poem The Love Song of J.Alfred Prufrock reveals the disappointment,loss,confusion and lack of faith that prevailed in Western society after the Worl...T.S.Eliot was a leader of the Modernist movement in poetry.His early poem The Love Song of J.Alfred Prufrock reveals the disappointment,loss,confusion and lack of faith that prevailed in Western society after the World WarⅠ.In this paper,the text of Love Song will be assessed from the perspective of intertextuality through the connection of the fantasy world and the disconnection of the real world.展开更多
Based on “locality” considerations, John Stuart Bell and his followers have derived inequalities and theorems that, when taken together with actual experiments that have been performed by Aspect and others, appear t...Based on “locality” considerations, John Stuart Bell and his followers have derived inequalities and theorems that, when taken together with actual experiments that have been performed by Aspect and others, appear to contradict physical reality as defined by Einstein. However, their specifically applied concept of locality is in conflict with the Fundamental Model of probability theory and the set theoretic definition of conditional probabilities. Bell-type inequalities are, therefore, not adequate to decide ponderous questions regarding physical reality.展开更多
We demonstrate that a Bell type of experiment asks the impossible of a Kolmogorovian correlation. An Einstein locality explanation in Bell’s format is therefore excluded beforehand by way of the experimental and stat...We demonstrate that a Bell type of experiment asks the impossible of a Kolmogorovian correlation. An Einstein locality explanation in Bell’s format is therefore excluded beforehand by way of the experimental and statistical method followed.展开更多
With the use of a local dependency on instrument setting parameters of the probability density of local hidden variables, it is demonstrated that a Kolmogorov formulation reproduces the quantum correlation. This is th...With the use of a local dependency on instrument setting parameters of the probability density of local hidden variables, it is demonstrated that a Kolmogorov formulation reproduces the quantum correlation. This is the novelty of the work. In a Bell experiment, one cannot distinguish between Bell’s formula and the here presented local Kolmogorov formula. With the presented formula, no CHSH can be obtained. Therefore, the famous CHSH inequality has no excluding power concerning local extra Einstein parameter models. This result concurs with other previous research concerning difficulties with Bell’s formula.展开更多
文摘BACKGROUND Bell’s palsy is an idiopathic facial palsy with an unknown cause,and 75%of patients heal spontaneously.However,the other 25%of patients continue experiencing mild or severe disabilities,resulting in a reduced quality of life.Currently,various treatment methods have been developed to treat this disease.However,there is controversy regarding their effectiveness,and new alternative treatments are needed.CASE SUMMARY The patient suffered from left-sided facial paralysis due to Bell’s palsy for 7 years.The patient received an uncultured umbilical cord-derived mesenchymal stem cell transplant eight times for treatment.After follow-up for 32 mo,the paralysis was cured,and there was no recurrence.CONCLUSION Uncultured umbilical cord-derived mesenchymal stem cell transplantation may be a potential treatment for patients with Bell’s palsy who do not spontaneously recover.
文摘Introduction: Bell’s palsy is an uncommon adverse effect of the COVID-19 vaccine that has been reported in clinical trials. Even though a few studies have linked the vaccination to Bell’s palsy, the actual mechanism is uncertain. Objectives: To describe the demographic data and COVID-19 vaccines-related data with Bell’s palsy in a tertiary centre of Malaysia, Hospital Kuala Lumpur. Methods: A retrospective cross-sectional study was observed among vaccinated recipients who developed Bell’s palsy within 60 days and sought treatment in the Otorhinolaryngology Department Hospital Kuala Lumpur, Malaysia between 1<sup>st</sup> May 2021 and 30<sup>th</sup> November 2021. The demographic data, clinical history, and vaccination history were collected from clinical records. The facial paralysis was graded according to the House-Brackmann grading system. Results: A total of 26 patients with a mean age was 38.5 years;higher incidence in younger age, below 60 years old (n = 24), specifically 18 - 30 years old (n = 11). We observed an equal number in relation to gender and onset (after the first or second dose) of facial palsy. Predominantly were Malay (n = 21) and only 6 patients had comorbidities. We found there was no difference in regard to the type of vaccine among Bell’s palsy patients;Pfizer (n = 9), followed by Sinovac (n = 9) and AstraZeneca (n = 8). Conclusion: Bell’s palsy was found to be a possible adverse event of the COVID-19 vaccine. Younger groups were noted as susceptible to this rare adverse effect. However, the benefits of vaccination outweigh the risk of Bell’s palsy, which has a good prognosis. More research with larger samples is needed to determine the true relationship between vaccination and Bell’s palsy.
文摘J. S. Bell’s well-known proofs of inequalities (and related work) are shown to be invalidated by two counter-arguments (-examples) that are based on Einstein-local propositions: Bell-type inequalities of Einstein-Podolsky-Rosen experiments must include, as virtually all physical theories do, elements of physical reality and their mathematical representations that relate to continua as opposed to exclusively finite numbers. Furthermore, Bell-type inequalities must be valid for all possible experimental geometries that lead to the quantum result. Based on these propositions, violations of Bell-type inequalities are demonstrated without violating Einstein locality, without conspiracy type theories and even for the case that all known “loopholes” are closed.
文摘We report a case of a rare sporadic Vestibular Schwannoma of a 9-month-old girl who had a right-sided lower motor type facial nerve palsy. The patient was initially diagnosed with Bell’s palsy and received steroid treatment accordingly, two months later the patient’s condition deteriorated, and further evaluation of CT and MRI brain was conducted that showed a mass lesion in the posterior fossa causing compression on the facial nerve. Misdiagnosis of facial nerve paralysis is common among children due to multiple related etiologies and varying rates of incidence in comparison to adults. The authors hope to address this issue in this report. Background: Facial nerve paralysis has been a matter of concern for many researchers to understand its nature, causes and presentation according to different age groups. In adults, Bell’s palsy (BP), the idiopathic form of facial nerve paralysis, is more common compared to children where most cases are due to secondary etiologies. Therefore, pediatricians are in an important position to identify these patients early in order to launch the most effective diagnostic and treatment approaches.
基金supported by a grant from the National Natural Science Foundation of China,No.81273848
文摘OBJECTIVE： To assess the efficacy of acupuncture combined with vitamin B12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell＇s palsy. DATA RETRIEVAL： A computer-based online retrieval of Medline, Web of Science, CNKI, CBM databases until April 2014 was performed for relevant trials, using the key words ＂Bell＇s palsy or idiopathic facial palsy or facial palsy＂ and＂acupuncture or vitamin B12 or methylcobalamin＂. STUDY SELECTION： All randomized controlled trials that compared acupuncture with acupuncture combined with vitamin B12 in patients with Bell＇s palsy were included in the me- ta-analysis. The initial treatment lasted for at least 4 weeks. The outcomes of incomplete facial recovery were monitored. The scoring index varied and the definition of healing was consistent. The combined effect size was calculated by using relative risk （RR） with 95% confidence interval （C/） using the fixed effect model of Review Manager. MAIN OUTCOME MEASURES： Incomplete recovery rates were chosen as the primary outcome. RESULTS： Five studies involving 344 patients were included in the final analysis. Results showed that the incomplete recovery rate of Bell＇s palsy patients was 44.50% in the acupuncture combined with vitamin B12 group but 62.57% in the acupuncture alone group. The major acupoints were Taiyang （EX-HN5）, Jiache （ST6）, Dicang （ST4） and Sibai （ST2）. The combined effect size showed that acupuncture combined with vitamin B12 was better than acupuncture alone for the treatment of Belrs palsy （RR = 0.71, 95%CI： 0.58-0.87; P = 0.001）, this result held true when 8 patients lost to follow up in one study were included into the analyses （RR = 0.70, 95%CI： 0.58-0.86; P = 0.0005）. In the subgroup analyses, the therapeutic effect in patients of the electroacupuncture subgroup was better than in the non-electroacupuncture subgroup （P = 0.024）. There was no significant dif- ference in the incomplete recovery rate by subgroup analysis on drug types and treatment period. Most of the included studies were moderate or low quality, and bias existed. CONCLUSION： In patients with Bell＇s palsy, acupuncture combined with vitamin 812 can reduce the risk of incomplete recovery compared with acupuncture alone in our meta-analysis. Because of study bias and methodological limitations, this conclusion is uncertain and the clinical appli- cation of acupuncture combined with vitamin B12 requires further exploration.
文摘T.S.Eliot was a leader of the Modernist movement in poetry.His early poem The Love Song of J.Alfred Prufrock reveals the disappointment,loss,confusion and lack of faith that prevailed in Western society after the World WarⅠ.In this paper,the text of Love Song will be assessed from the perspective of intertextuality through the connection of the fantasy world and the disconnection of the real world.
文摘Based on “locality” considerations, John Stuart Bell and his followers have derived inequalities and theorems that, when taken together with actual experiments that have been performed by Aspect and others, appear to contradict physical reality as defined by Einstein. However, their specifically applied concept of locality is in conflict with the Fundamental Model of probability theory and the set theoretic definition of conditional probabilities. Bell-type inequalities are, therefore, not adequate to decide ponderous questions regarding physical reality.
文摘We demonstrate that a Bell type of experiment asks the impossible of a Kolmogorovian correlation. An Einstein locality explanation in Bell’s format is therefore excluded beforehand by way of the experimental and statistical method followed.
文摘With the use of a local dependency on instrument setting parameters of the probability density of local hidden variables, it is demonstrated that a Kolmogorov formulation reproduces the quantum correlation. This is the novelty of the work. In a Bell experiment, one cannot distinguish between Bell’s formula and the here presented local Kolmogorov formula. With the presented formula, no CHSH can be obtained. Therefore, the famous CHSH inequality has no excluding power concerning local extra Einstein parameter models. This result concurs with other previous research concerning difficulties with Bell’s formula.
