A new method for filling bone cavity with a graft of frozen-decalcified-defatted-driedallogeneic (FDDDA) cancellous bone was described.This method was used for the treatment of cavi-ties after the enucleation of jaw c...A new method for filling bone cavity with a graft of frozen-decalcified-defatted-driedallogeneic (FDDDA) cancellous bone was described.This method was used for the treatment of cavi-ties after the enucleation of jaw cysts in 10 patients from December 1985 to February 1990.Thewounds of 9 patients healed by first intension,but wound infection occurred in one case postopera-tively.The 9 patients,besides the patient who suffered from wound infection,were followed up for5 to 56 months,with an average of 41.1 months.Evidence of recurrence with jaw cyst.was not ob-served.展开更多
The growth and enlargement of jaw cysts are associated with raised intracystic pressure and bone resorption surrounding the cysts.The major bone-resorbing cells are the osteoclasts.They are acting under the influence ...The growth and enlargement of jaw cysts are associated with raised intracystic pressure and bone resorption surrounding the cysts.The major bone-resorbing cells are the osteoclasts.They are acting under the influence of local bone-resorbing factors: prostaglandins,proteinases and cytokines.It was found that positive pressure enhanced the expression of IL-1αmRNA and protein in epithelial cells of odontogenic keratocyst,and increased the secretion of matrix metalloproteinase and PGE2 in a co-culture of odontogenic keratocyst fibroblasts and epithelial cells.However,the signal intensities for IL-1α mRNA and protein in the epithelium were significantly decreased after marsupialization which relived intracystic pressure.Experimental study indicated that intermittent negative pressure could promote osteogenesis in human bone marrow-derived stroma cells(BMSCs) in vitro.We propose a hypothesis that bone formation around the cyst of the jaws would be stimulated by intracystic negative pressure.展开更多
目的:探讨颌骨单纯性骨囊肿(simple bone cyst,SBC)的临床诊断要点。方法:选择南昌大学附属口腔医院口腔颌面外科2010—2020年间收治的63例SBC及100例颌骨囊肿患者作为研究对象,收集2组患者的临床、影像学及手术资料,采用筛检试验评价...目的:探讨颌骨单纯性骨囊肿(simple bone cyst,SBC)的临床诊断要点。方法:选择南昌大学附属口腔医院口腔颌面外科2010—2020年间收治的63例SBC及100例颌骨囊肿患者作为研究对象,收集2组患者的临床、影像学及手术资料,采用筛检试验评价的方法探讨SBC的临床诊断要点,从而为该疾病的临床诊断及治疗方式的选择提供依据。结果:本研究共纳入63例SBC患者,其平均诊断年龄为20岁(7~79岁)。其中,上颌骨2例,下颌骨61例。采用串联实验进行筛检变量组合,结果显示,x1(年龄分组)和x3(体格检查有无阳性体征)组合的受试者工作特征曲线下面积(area under the curve,AUC)为0.831,灵敏度为68.18%,特异度为98.10%,约登指数为0.6628;x2(部位:上/下)和x3组合的AUC为0.865,灵敏度为86.36%,特异度为86.67%,约登指数为0.7303;x1、x3、x5(骨质是否膨隆、吸收)组合的AUC为0.776,灵敏度为56.06%,特异度为99.05%,约登指数为0.5511。结论:年龄小于20岁、体格检查无阳性体征、影像学表现为边界清楚的单房型囊性透射影,且颌骨无明显骨质膨隆的患者可以初步诊断为SBC。展开更多
目的:探讨骨增量技术联合颌骨囊肿刮治术治疗牙源性颌骨囊肿的修复及美学效果。方法:选取2017年3月-2022年3月于笔者医院收治的100例颌骨囊肿患者为研究对象,随机分为对照组和观察组。对照组给予颌骨囊肿刮治术治疗,观察组在对照组的基...目的:探讨骨增量技术联合颌骨囊肿刮治术治疗牙源性颌骨囊肿的修复及美学效果。方法:选取2017年3月-2022年3月于笔者医院收治的100例颌骨囊肿患者为研究对象,随机分为对照组和观察组。对照组给予颌骨囊肿刮治术治疗,观察组在对照组的基础上给予引导骨再生(Guided bone regeneration,GBR)技术。比较两组患者围手术期指标(术中出血量、手术时间、住院时间),修复效果(囊肿体积缩小度、骨质增生厚度、骨密度),美学效果(红色美学标准)及术后并发症发生率。结果:观察组术中出血量、手术时间均高于对照组(P<0.05),观察组住院时间与对照组比较,差异无统计学意义(P>0.05)。观察组囊肿体积缩小度、骨质增生厚度及骨密度均高于对照组(P<0.05),观察组红色美学标准评分高于对照组(P<0.05)。观察组不良反应发生率(14.00%)低于对照组(32.00%)(P<0.05)。结论:GBR技术联合颌骨囊肿刮除术可有效提高牙源性颌骨囊肿患者骨缺损修复效果,缩小囊腔体积,促进骨质发育,同时获得更好的美学效果,降低术后并发症的发生,安全可靠。展开更多
文摘A new method for filling bone cavity with a graft of frozen-decalcified-defatted-driedallogeneic (FDDDA) cancellous bone was described.This method was used for the treatment of cavi-ties after the enucleation of jaw cysts in 10 patients from December 1985 to February 1990.Thewounds of 9 patients healed by first intension,but wound infection occurred in one case postopera-tively.The 9 patients,besides the patient who suffered from wound infection,were followed up for5 to 56 months,with an average of 41.1 months.Evidence of recurrence with jaw cyst.was not ob-served.
文摘The growth and enlargement of jaw cysts are associated with raised intracystic pressure and bone resorption surrounding the cysts.The major bone-resorbing cells are the osteoclasts.They are acting under the influence of local bone-resorbing factors: prostaglandins,proteinases and cytokines.It was found that positive pressure enhanced the expression of IL-1αmRNA and protein in epithelial cells of odontogenic keratocyst,and increased the secretion of matrix metalloproteinase and PGE2 in a co-culture of odontogenic keratocyst fibroblasts and epithelial cells.However,the signal intensities for IL-1α mRNA and protein in the epithelium were significantly decreased after marsupialization which relived intracystic pressure.Experimental study indicated that intermittent negative pressure could promote osteogenesis in human bone marrow-derived stroma cells(BMSCs) in vitro.We propose a hypothesis that bone formation around the cyst of the jaws would be stimulated by intracystic negative pressure.
文摘目的:探讨颌骨单纯性骨囊肿(simple bone cyst,SBC)的临床诊断要点。方法:选择南昌大学附属口腔医院口腔颌面外科2010—2020年间收治的63例SBC及100例颌骨囊肿患者作为研究对象,收集2组患者的临床、影像学及手术资料,采用筛检试验评价的方法探讨SBC的临床诊断要点,从而为该疾病的临床诊断及治疗方式的选择提供依据。结果:本研究共纳入63例SBC患者,其平均诊断年龄为20岁(7~79岁)。其中,上颌骨2例,下颌骨61例。采用串联实验进行筛检变量组合,结果显示,x1(年龄分组)和x3(体格检查有无阳性体征)组合的受试者工作特征曲线下面积(area under the curve,AUC)为0.831,灵敏度为68.18%,特异度为98.10%,约登指数为0.6628;x2(部位:上/下)和x3组合的AUC为0.865,灵敏度为86.36%,特异度为86.67%,约登指数为0.7303;x1、x3、x5(骨质是否膨隆、吸收)组合的AUC为0.776,灵敏度为56.06%,特异度为99.05%,约登指数为0.5511。结论:年龄小于20岁、体格检查无阳性体征、影像学表现为边界清楚的单房型囊性透射影,且颌骨无明显骨质膨隆的患者可以初步诊断为SBC。
文摘目的:探讨骨增量技术联合颌骨囊肿刮治术治疗牙源性颌骨囊肿的修复及美学效果。方法:选取2017年3月-2022年3月于笔者医院收治的100例颌骨囊肿患者为研究对象,随机分为对照组和观察组。对照组给予颌骨囊肿刮治术治疗,观察组在对照组的基础上给予引导骨再生(Guided bone regeneration,GBR)技术。比较两组患者围手术期指标(术中出血量、手术时间、住院时间),修复效果(囊肿体积缩小度、骨质增生厚度、骨密度),美学效果(红色美学标准)及术后并发症发生率。结果:观察组术中出血量、手术时间均高于对照组(P<0.05),观察组住院时间与对照组比较,差异无统计学意义(P>0.05)。观察组囊肿体积缩小度、骨质增生厚度及骨密度均高于对照组(P<0.05),观察组红色美学标准评分高于对照组(P<0.05)。观察组不良反应发生率(14.00%)低于对照组(32.00%)(P<0.05)。结论:GBR技术联合颌骨囊肿刮除术可有效提高牙源性颌骨囊肿患者骨缺损修复效果,缩小囊腔体积,促进骨质发育,同时获得更好的美学效果,降低术后并发症的发生,安全可靠。
