By using the MD approach, this study aims at making a comparison between the lexical features in W. J. F. Jenner’s and Wang Yitong’s translations of Luoyang Jialan Ji (547 AD) from a multidimensional perspective. St...By using the MD approach, this study aims at making a comparison between the lexical features in W. J. F. Jenner’s and Wang Yitong’s translations of Luoyang Jialan Ji (547 AD) from a multidimensional perspective. Statistics show that both the two translations belong to the General Narrative Exposition Register. However, there are significant discrepancies between the two versions in Dimension 1 “Involved versus Informational Production”, Dimension 4 “Overt Expression of Persuasion” and Dimension 5 “Abstract versus Non-Abstract Information”. The differences in Dimension 2 “Narrative versus Non-Narrative Concerns” and Dimension 3 “Explicit versus Situation-Dependent Reference” are not that significant. It is found that in Dimension 1, the information density of Wang’s version is much higher than that of Jenner’s. In Dimension 4, Wang’s version contains more overt persuasive effort than Jenner’s. In Dimension 5, the positive and negative contrast between the two versions indicates that Wang’s version provides information in a more abstract way, whereas Jenner’s in a relatively non-abstract way. Combined with typical examples in the two translation versions, this study is hoped to help better understand the translations of Luoyang Jialan Ji and conduct future studies on the translation styles of the two translators.展开更多
BACKGROUND Hepatocellular carcinoma(HCC)is one of the most common digestive system cancers with high mortality rates worldwide.The main ingredients in Mu Ji Fang Granules(MJF)are alkaloids,flavonoids,and polysaccharid...BACKGROUND Hepatocellular carcinoma(HCC)is one of the most common digestive system cancers with high mortality rates worldwide.The main ingredients in Mu Ji Fang Granules(MJF)are alkaloids,flavonoids,and polysaccharides.MJF has been used in the clinical treatment of hepatitis,cirrhosis and HCC for more than 30 years.Few previous studies have focused on the mechanism of MJF on tumor immunology in the treatment of HCC.AIM To explore the mechanism of action of MJF on tumor immunology in the treatment of HCC.METHODS The absorbable ingredients of MJF were identified using Molecule Network related to High Performance Liquid Chromatography-Electron Spray Ionization-Time of Flight-Mass Spectrometry,and hub potential anti-HCC targets were screened using network pharmacology and pathway enrichment analysis.Forty male mice were randomly divided into the Blank,Model,and MJF groups(1.8,5.4,and 10.8 g/kg/d)following 7 d of oral administration.Average body weight gain,spleen and thymus indices were calculated,tumor tissues were stained with hematoxylin and eosin,and Interferon gamma(IFN-γ),Tumor necrosis factorα(TNF-α),Interleukin-2,aspartate aminotransferase,alanine aminotransferase,alpha-fetoprotein(AFP),Fas,and FasL were measured by Enzyme-linked Immunosorbent Assay.Relevant mRNA expression of Bax and Bcl2 was evaluated by Real Time Quantitative PCR(RTqPCR)and protein expression of Transforming growth factorβ1(TGF-β1)and Mothers against decapentaplegic homolog(SMAD)4 was assessed by Western blotting.The HepG2 cell line was treated with 10 mg/mL,20 mg/mL,30 mg/mL,40 mg/mL of MJF,and another 3 groups were treated with TGF-β1 inhibitor(LY364947)and different doses of MJF.Relevant mRNA expression of TNF-α,IFN-γ,Bax and Bcl2 was evaluated by RT-qPCR and protein expression of TGF-β1,SMAD2,p-SMAD2,SMAD4,and SMAD7 was assessed by Western blotting.RESULTS It was shown that MJF improved body weight gain and tumor inhibition rate in H22 tumorbearing mice,protected immune organs and liver function,reduced the HCC indicator AFP,affected immunity and apoptosis,and up-regulated the TGF-β1/SMAD signaling pathway,by increasing the relative expression of TGF-β1,SMAD2,p-SMAD2 and SMAD4 and decreasing SMAD7,reducing immune factors TNF-αand IFN-γ,decreasing apoptosis cytokines Fas,FasL and Bcl2/Bax,and inhibiting the effect of LY364947 in HepG2 cells.CONCLUSION MJF inhibits HCC by activating the TGF-β1/SMAD signaling pathway,and affecting immune and apoptotic cytokines,which may be due to MJF adjusting immune escape and apoptosis.展开更多
Lu Xun’s short stories play a prominent role in the history of modern Chinese literature,and a number of Sinologists have studied them and published their English translations.This paper selects“YīJiàn Xiǎo S...Lu Xun’s short stories play a prominent role in the history of modern Chinese literature,and a number of Sinologists have studied them and published their English translations.This paper selects“YīJiàn Xiǎo Shì”in Lu Xun’s collection“Call to Arms”as the object of study,taking hypotaxis and parataxis as the starting point,and compares the translation of Yang Hsien-yi and Gladys Yang with the original version,studying the differences between the them in the process of C-E translation.It is hoped that some flexible conversion strategies in English-Chinese translation can be learned from the translation research.展开更多
Objective To observe the clinical therapeutic effects of Jiájǐ（夹脊EX-B2） on spastic cerebral palsy （SOP） with acupuncture.Methods 62 cases of SOP were randomized into two groups,named treat- ment group with...Objective To observe the clinical therapeutic effects of Jiájǐ（夹脊EX-B2） on spastic cerebral palsy （SOP） with acupuncture.Methods 62 cases of SOP were randomized into two groups,named treat- ment group with acupuncture on Jiájǐ（夹脊EX-B2）,and control group with sham-acupuncture.The treatment was applied once a day,10 times made a course,totally 6 courses were required.Modified Ashworth scale and FIM grade were used to observe and assess the results of treatment.Results The total effective rate was 84.4 % in treatment group and was 63.3 % in control group,indicating significant difference （P〈0.01）. Conclusion Acupuncture on Jiájǐ（夹脊EX-B2） achieves good clinical therapeutic effects on SCP.展开更多
By using GIS, RS and landscape ecology, LandsatTM (1993 and 2009) and ETM (2001) remote sensing images of Licheng District of Ji’nan City, Shandong Province were interpreted, and dynamic changes of landscape pattern ...By using GIS, RS and landscape ecology, LandsatTM (1993 and 2009) and ETM (2001) remote sensing images of Licheng District of Ji’nan City, Shandong Province were interpreted, and dynamic changes of landscape pattern in the district were analyzed at the levels of class and landscape. The results showed that during the 16 years the landscape pattern in the district had changed significantly. (a) From the perspective of patch category, areas of arable land, woodland and grassland decreased unceasingly, and arable land accounted for the largest reduction from 488.15 km 2 in 1993 down to 324.37 km 2 in 2009, witnessing a reduction rate of 33.56%. But the patch quantity and fragmentation increased, patch connectivity reduced. Spatial pattern of construction land expanded and its area witnessed a significant increase of 147.05%. Patch cohesion index increased and connectivity grew better. (b) From the perspective of overall landscape, patch quantity, contagion and perimeter-area fractal dimension decreased, patch shape became simple, the Shannon’s diversity index, Shannon’s evenness index and splitting index increased, landscape heterogeneity rose. With the rapid social and economic development, landscape pattern will be more and more influenced by human behaviors展开更多
简要介绍目标转矩、目标预紧力以及螺栓弹性交互作用对法兰密封的影响,阐明螺栓法兰连接的正确安装对密封的可靠性、施工效率有很大影响,然后引入日本标准JIS B 2251—2008《压力边界法兰连接螺栓紧固程序》,结合ASME PCC-1—2013和前...简要介绍目标转矩、目标预紧力以及螺栓弹性交互作用对法兰密封的影响,阐明螺栓法兰连接的正确安装对密封的可靠性、施工效率有很大影响,然后引入日本标准JIS B 2251—2008《压力边界法兰连接螺栓紧固程序》,结合ASME PCC-1—2013和前人的研究成果,对该标准的适用范围、目标转矩的设定、注意事项、加载过程、目标预紧力获取率以及其衍生方法分别进行介绍和分析,总结出该标准具有施工效率高,螺栓载荷离散度低的特点,值得推广使用。展开更多
文摘By using the MD approach, this study aims at making a comparison between the lexical features in W. J. F. Jenner’s and Wang Yitong’s translations of Luoyang Jialan Ji (547 AD) from a multidimensional perspective. Statistics show that both the two translations belong to the General Narrative Exposition Register. However, there are significant discrepancies between the two versions in Dimension 1 “Involved versus Informational Production”, Dimension 4 “Overt Expression of Persuasion” and Dimension 5 “Abstract versus Non-Abstract Information”. The differences in Dimension 2 “Narrative versus Non-Narrative Concerns” and Dimension 3 “Explicit versus Situation-Dependent Reference” are not that significant. It is found that in Dimension 1, the information density of Wang’s version is much higher than that of Jenner’s. In Dimension 4, Wang’s version contains more overt persuasive effort than Jenner’s. In Dimension 5, the positive and negative contrast between the two versions indicates that Wang’s version provides information in a more abstract way, whereas Jenner’s in a relatively non-abstract way. Combined with typical examples in the two translation versions, this study is hoped to help better understand the translations of Luoyang Jialan Ji and conduct future studies on the translation styles of the two translators.
基金Supported by National Natural Science Foundation of China,No.81874342Natural Science Foundation of Liaoning Province,No.2020-MZLH-35.
文摘BACKGROUND Hepatocellular carcinoma(HCC)is one of the most common digestive system cancers with high mortality rates worldwide.The main ingredients in Mu Ji Fang Granules(MJF)are alkaloids,flavonoids,and polysaccharides.MJF has been used in the clinical treatment of hepatitis,cirrhosis and HCC for more than 30 years.Few previous studies have focused on the mechanism of MJF on tumor immunology in the treatment of HCC.AIM To explore the mechanism of action of MJF on tumor immunology in the treatment of HCC.METHODS The absorbable ingredients of MJF were identified using Molecule Network related to High Performance Liquid Chromatography-Electron Spray Ionization-Time of Flight-Mass Spectrometry,and hub potential anti-HCC targets were screened using network pharmacology and pathway enrichment analysis.Forty male mice were randomly divided into the Blank,Model,and MJF groups(1.8,5.4,and 10.8 g/kg/d)following 7 d of oral administration.Average body weight gain,spleen and thymus indices were calculated,tumor tissues were stained with hematoxylin and eosin,and Interferon gamma(IFN-γ),Tumor necrosis factorα(TNF-α),Interleukin-2,aspartate aminotransferase,alanine aminotransferase,alpha-fetoprotein(AFP),Fas,and FasL were measured by Enzyme-linked Immunosorbent Assay.Relevant mRNA expression of Bax and Bcl2 was evaluated by Real Time Quantitative PCR(RTqPCR)and protein expression of Transforming growth factorβ1(TGF-β1)and Mothers against decapentaplegic homolog(SMAD)4 was assessed by Western blotting.The HepG2 cell line was treated with 10 mg/mL,20 mg/mL,30 mg/mL,40 mg/mL of MJF,and another 3 groups were treated with TGF-β1 inhibitor(LY364947)and different doses of MJF.Relevant mRNA expression of TNF-α,IFN-γ,Bax and Bcl2 was evaluated by RT-qPCR and protein expression of TGF-β1,SMAD2,p-SMAD2,SMAD4,and SMAD7 was assessed by Western blotting.RESULTS It was shown that MJF improved body weight gain and tumor inhibition rate in H22 tumorbearing mice,protected immune organs and liver function,reduced the HCC indicator AFP,affected immunity and apoptosis,and up-regulated the TGF-β1/SMAD signaling pathway,by increasing the relative expression of TGF-β1,SMAD2,p-SMAD2 and SMAD4 and decreasing SMAD7,reducing immune factors TNF-αand IFN-γ,decreasing apoptosis cytokines Fas,FasL and Bcl2/Bax,and inhibiting the effect of LY364947 in HepG2 cells.CONCLUSION MJF inhibits HCC by activating the TGF-β1/SMAD signaling pathway,and affecting immune and apoptotic cytokines,which may be due to MJF adjusting immune escape and apoptosis.
基金The paper is part of the achievements of“Research of the English Translation of Lu Xun’s Short Stories and Their Dissemination”(鲁迅小说英译及传播研究),a Shanghai City College Students’project in 2023.Its serial number is SH2023141.
文摘Lu Xun’s short stories play a prominent role in the history of modern Chinese literature,and a number of Sinologists have studied them and published their English translations.This paper selects“YīJiàn Xiǎo Shì”in Lu Xun’s collection“Call to Arms”as the object of study,taking hypotaxis and parataxis as the starting point,and compares the translation of Yang Hsien-yi and Gladys Yang with the original version,studying the differences between the them in the process of C-E translation.It is hoped that some flexible conversion strategies in English-Chinese translation can be learned from the translation research.
文摘Objective To observe the clinical therapeutic effects of Jiájǐ（夹脊EX-B2） on spastic cerebral palsy （SOP） with acupuncture.Methods 62 cases of SOP were randomized into two groups,named treat- ment group with acupuncture on Jiájǐ（夹脊EX-B2）,and control group with sham-acupuncture.The treatment was applied once a day,10 times made a course,totally 6 courses were required.Modified Ashworth scale and FIM grade were used to observe and assess the results of treatment.Results The total effective rate was 84.4 % in treatment group and was 63.3 % in control group,indicating significant difference （P〈0.01）. Conclusion Acupuncture on Jiájǐ（夹脊EX-B2） achieves good clinical therapeutic effects on SCP.
文摘By using GIS, RS and landscape ecology, LandsatTM (1993 and 2009) and ETM (2001) remote sensing images of Licheng District of Ji’nan City, Shandong Province were interpreted, and dynamic changes of landscape pattern in the district were analyzed at the levels of class and landscape. The results showed that during the 16 years the landscape pattern in the district had changed significantly. (a) From the perspective of patch category, areas of arable land, woodland and grassland decreased unceasingly, and arable land accounted for the largest reduction from 488.15 km 2 in 1993 down to 324.37 km 2 in 2009, witnessing a reduction rate of 33.56%. But the patch quantity and fragmentation increased, patch connectivity reduced. Spatial pattern of construction land expanded and its area witnessed a significant increase of 147.05%. Patch cohesion index increased and connectivity grew better. (b) From the perspective of overall landscape, patch quantity, contagion and perimeter-area fractal dimension decreased, patch shape became simple, the Shannon’s diversity index, Shannon’s evenness index and splitting index increased, landscape heterogeneity rose. With the rapid social and economic development, landscape pattern will be more and more influenced by human behaviors
文摘简要介绍目标转矩、目标预紧力以及螺栓弹性交互作用对法兰密封的影响,阐明螺栓法兰连接的正确安装对密封的可靠性、施工效率有很大影响,然后引入日本标准JIS B 2251—2008《压力边界法兰连接螺栓紧固程序》,结合ASME PCC-1—2013和前人的研究成果,对该标准的适用范围、目标转矩的设定、注意事项、加载过程、目标预紧力获取率以及其衍生方法分别进行介绍和分析,总结出该标准具有施工效率高,螺栓载荷离散度低的特点,值得推广使用。
