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Bowel preparation protocol for hospitalized patients ages 50 years or older:A randomized controlled trial 被引量:1
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作者 Yu He Qi Liu +3 位作者 Yi-Wen Chen Li-Jian Cui Kai Cao Zi-Hao Guo 《World Journal of Gastrointestinal Endoscopy》 2024年第1期18-28,共11页
BACKGROUND The incidence and mortality rate of colorectal cancer progressively increase with age and become particularly prominent after the age of 50 years.Therefore,the population that is≥50 years in age requires l... BACKGROUND The incidence and mortality rate of colorectal cancer progressively increase with age and become particularly prominent after the age of 50 years.Therefore,the population that is≥50 years in age requires long-term and regular colonoscopies.Uncomfortable bowel preparation is the main reason preventing patients from undergoing regular colonoscopies.The standard bowel preparation regimen of 4-L polyethylene glycol(PEG)is effective but poorly tolerated.AIM To investigate an effective and comfortable bowel preparation regimen for hospitalized patients≥50 years in age.METHODS Patients were randomly assigned to group 1(2-L PEG+30-mL lactulose+a lowresidue diet)or group 2(4-L PEG).Adequate bowel preparation was defined as a Boston bowel preparation scale(BBPS)score of≥6,with a score of≥2 for each segment.Non-inferiority was prespecified with a margin of 10%.Additionally,the degree of comfort was assessed based on the comfort questionnaire.RESULTS The proportion of patients with a BBPS score of≥6 in group 1 was not significantly different from that in group 2,as demonstrated by intention-to-treat(91.2%vs 91.0%,P=0.953)and per-protocol(91.8%vs 91.0%,P=0.802)analyses.Furthermore,in patients≥75 years in age,the proportion of BBPS scores of≥6 in group 1 was not significantly different from that in group 2(90.9%vs 97.0%,P=0.716).Group 1 had higher comfort scores(8.85±1.162 vs 7.59±1.735,P<0.001),longer sleep duration(6.86±1.204 h vs 5.80±1.730 h,P<0.001),and fewer awakenings(1.42±1.183 vs 2.04±1.835,P=0.026)than group 2.CONCLUSION For hospitalized patients≥50 years in age,the bowel preparation regimen comprising 2-L PEG+30-mL lactulose+a low-residue diet produced a cleanse that was as effective as the 4-L PEG regimen and even provided better comfort. 展开更多
关键词 Aged 50 years or older HOSPITALIZED 2-L polyethylene-glycol+30-mL lactulose+a low-residue diet Comfort
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Epidemiology of Cardiovascular Mortality in Patients under 60 Years Old in a Cardiology Department in West Africa, Dakar-Senegal
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作者 Aliou Alassane Ngaide Ngone Diaba Gaye +5 位作者 Joseph Salvador Mingou Mame Diarra Sene Momar Dioum Mouhamadou Bamba Ndiaye Alassane Mbaye Abdoul Kane 《World Journal of Cardiovascular Diseases》 CAS 2024年第8期502-514,共13页
Background: Our study aimed to examine cardiovascular mortality within the working-age population, exploring epidemiological, clinical, and paraclinical features, complications, and identifying etiological factors lin... Background: Our study aimed to examine cardiovascular mortality within the working-age population, exploring epidemiological, clinical, and paraclinical features, complications, and identifying etiological factors linked to mortality. Methods: We conducted a descriptive and analytical retrospective study from September 2019 to August 2022 at the General Hospital Idrissa POUYE in Dakar, we reviewed all the medical records of patients from 15 to 60 years old who died while admitted in the cardiology department. Data collected were socioeconomic status, clinical history, type of cardiovascular disaese, length of hospitalization, circumstances and timing of death. The data were analyzed with R. Studio version 2022.12.0 + 353 and Excel 2019, with a P-value Results: The study included 73 patients, indicating a specific mortality rate of 8.8% and a proportional mortality of 39%. Predominantly male (sex ratio 1.2), the average age was 44. Key cardiovascular risk factors identified were sedentarism (76.7%), hypertension (28.8%), and smoking (21.9%). The leading cause for consultation was dyspnea (72.6%). Notable findings included a majority of patients presenting with general condition deterioration (90%) and cardiovascular collapse upon admission (23.3%). Physical exam revealed signs of heart failure in 63%. Echocardiography showed left ventricular ejection fraction impairment (81%) and pulmonary hypertension (78%). Immediate causes of death were primarily cardiogenic shock (45.2%) and septic shock (37%). The analytical study indicates that the data most closely associated with mortality were age, socio-economic level, ischemic heart disease (p = 0.034), rheumatic valvulopathies, pulmonary embolism (p = 0.034), hypertension (HTA) (p = 0.009), smoking (p = 0.011), diabetes (p = 0.011), dyslipidemias, prolonged bedrest (p = 0.001), morbid obesity (p = 0.001), and COVID-19 infection (p = 0.017). Conclusion: The prevalence of ischemic heart diseases, pulmonary embolisms, and valvulopathies in premature mortality statistics underscores the need for enhanced cardiovascular prevention efforts. 展开更多
关键词 Mortality Under 60 years CARDIOVASCULAR DAKAR
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Characteristics of the HIV/AIDS Epidemic among People Aged≥50 Years in China during 2018–2021
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作者 HOU Yu Shan JIN Yi Chen +3 位作者 CAI Chang TANG Hou Lin QIN Qian Qian LYU Fan 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第4期399-405,共7页
Objective This study aimed to determine the current epidemiological status of PLWHA aged≥50 years in China from 2018 to 2021.It also aimed to recommend targeted interventions for the prevention and treatment of HIV/A... Objective This study aimed to determine the current epidemiological status of PLWHA aged≥50 years in China from 2018 to 2021.It also aimed to recommend targeted interventions for the prevention and treatment of HIV/AIDS in elderly patients.Methods Data on newly reported cases of PLWHA,aged≥50 years in China from 2018 to 2021,were collected using the CRIMS.Trend tests and spatial analyses were also conducted.Results Between 2018 and 2021,237,724 HIV/AIDS cases were reported among patients aged≥50 years in China.The main transmission route was heterosexual transmission(91.24%).Commercial heterosexual transmission(CHC)was the primary mode of transmission among males,while non-marital non-CHC([NMNCHC];60.59%)was the prevalent route in women.The proportion of patients with CHC decreased over time(Z=67.716,P<0.01),while that of patients with NMNCHC increased(Z=153.05,P<0.01).The sex ratio varied among the different modes of infection,and it peaked at 17.65 for CHC.The spatial analysis indicated spatial clustering,and the high-high clustering areas were mainly distributed in the southwestern and central-southern provinces.Conclusion In China,PLWHA,aged≥50 years,were predominantly infected through heterosexual transmission.The primary modes of infection were CHC and NMNCHC.There were variations in the sex ratio among different age groups,infected through various sexual behaviors.HIV/AIDS cases exhibited spatial clustering.Based on these results,the expansion of HIV testing,treatment,and integrated behavioral interventions in high-risk populations is recommended to enhance disease detection in key regions. 展开更多
关键词 HIV/AIDS Aged≥50 years China
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Effect of a Nutrition Education Intervention on Food Safety Knowledge, Attitudes and Practices of Mothers of Children under 5 Years in the Peri-Urban Areas of Bobo-Dioulasso: Before and after Study
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作者 Alain Hien Jérome W. Somé +4 位作者 Olivier O. Sombié Isidore Traoré Augustin N. Zeba Georges Anicet Ouedraogo Roland Nâg-Tiero Meda 《Food and Nutrition Sciences》 CAS 2024年第5期401-420,共20页
Background: This study assessed the effect of a nutrition education intervention. This intervention aimed to improve the knowledge, attitudes, and practices of mothers on food safety in the peri-urban areas of Bobo-Di... Background: This study assessed the effect of a nutrition education intervention. This intervention aimed to improve the knowledge, attitudes, and practices of mothers on food safety in the peri-urban areas of Bobo-Dioulasso in Burkina Faso. Methods: A total of 243 mothers of children under 5 years in the peri-urban of Bobo-Dioulasso were administered the FAO questionnaire for food safety knowledge, attitudes, and practices assessment during two cross-sectional surveys, before and after the intervention, in January and October 2017. The intervention included two components consisting of a theoretical phase (counselling and discussion) and cooking demonstrations implemented for ten months. To account for the before-and-after design of the study, the McNemar’s test was used to assess the effect of the intervention on food safety KAP of mothers of children under 5 years. Results: The mean age of mothers was 29 ± 6.2 years and 50.6% of them were between 20 and 29 years old. One for knowledge (cooking thoroughly with, p-value = 0.0001) and another for attitudes (perceived benefits of reheating leftovers before eating them, p-value = 0.0001), significantly increased after the intervention. In terms of food safety practices, all the indicators (cleaning of dirty surfaces, plates and utensils and storage of perishable foods) significantly increased (all p = 0.0001 Conclusion: This study provided some evidence of an effective nutrition education intervention for improving maternal KAP on food safety for their child’s feeding. 展开更多
关键词 Nutrition Education Intervention KNOWLEDGE Attitudes and Practices Food Safety Mothers of Children under 5 years Burkina Faso
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Review of Two Years of Surgical Activities of the General Surgery Department of the Reference Health Center of Commune I of Bamako Mali
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作者 Tounkara Cheickna Cisse Amadou Beydi +5 位作者 Samake Hamidou Diarra Issaka Sanogo Modibo Diarra Bogoba Doumbia Seydou Yena Sadio 《Surgical Science》 2024年第4期195-206,共12页
The objectives of this work were to evaluate the surgical activities carried out in the general surgery department of the Reference Health Center of Commune I of Bamako, to describe the sociodemographic characteristic... The objectives of this work were to evaluate the surgical activities carried out in the general surgery department of the Reference Health Center of Commune I of Bamako, to describe the sociodemographic characteristics of the operated patients, to determine the main pathologies encountered and to evaluate qualitatively the result of the treatment. In order to improve performance, and the quality of care, and to identify common pathologies in the surgical department, we undertook a retrospective study on surgical activities from January 2009 to December 2010. At the end of this study, out of 474 men and 187 women (equal sex ratio 2.53);we were able to determine the frequency of surgical pathologies. Farmers, housewives and pupils/students were the most represented with 25.9% respectively;20% and 13.3%. The most frequently observed pathologies were wall hernia (44.8%), prostate adenoma (12%) and acute appendicitis (10.5%). The average length of hospitalization was 3.43 days. Infectious complications affected 25 patients (3.8% of cases) and a death rate of 0.45% (i.e. 3 patients). The average cost of care was 53,500 FCFA. Indeed, the reality of surgical practice in health centers was not the same because of the level of skills of practicing surgeons. 展开更多
关键词 Assessment Surgical Activities 2 years Reference Health Center of Commune I BAMAKO
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Factors Associated with Mortality in Children Aged 1 Month to 15 Years Hospitalized in the Pediatric Ward of the Kalaban-Coro Reference Health Center: Cross-Sectional Study
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作者 Abdoul Salam Diarra Mohamed Diarra +13 位作者 Dramane Touré Tawfiq Abu Beyadari Balilé Harber Maimouna Kanté Issa Guindo Belco Maiga Karamoko Sacko Kalirou Traoré Fatoumata Dicko Mamadou Togo Kalba Pélieba Mariam Sylla Mamadou Samaké Hamadoun Sangho 《Open Journal of Pediatrics》 2024年第5期800-813,共14页
Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in chi... Introduction: Infant and child mortality is a worldwide concern, but developing countries such as Mali are more affected. The aim of this study was to investigate morbidity and factors associated with mortality in children aged 1 month to 15 years. Methodology: This was a cross-sectional study which took place from January 1 to December 31, 2020 covering children aged 1 month to 15 years hospitalized at the Kalaban-Coro CSRéf. Data were entered into Excel and analyzed using SPSS version 20 software. Results: Five hundred children aged 1 months to 15 years were included. The age range 1 to 5 years (53.6%) and male sex (58.2%) were the most represented. Malaria (72.2%), acute respiratory infections (6.2%) and diarrhea/dehydration (3%) were the main morbidities. Mortality was estimated at 10.6%, and the two main causes of death were malaria (56.6%) and acute respiratory infections (7.54%). Univariate analysis revealed a statistically significant association between the dependent variable (death) and age (p Conclusion: This study confirms the high rate of infant and child morbidity and mortality in our health facilities. Strengthening human resources and intensifying behavior-change communication can help reverse the trend. 展开更多
关键词 Children Aged 1 Months to 15 years MORBIDITY Factors Associated with Mortality MORBIDITY
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Quality-adjusted life years and surgical waiting list:Systematic review of the literature
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作者 Roberto de la Plaza Llamas Lorena Ortega Azor +5 位作者 Marina Hernández Yuste Ludovica Gorini Raquel Aránzazu Latorre-Fragua Daniel Alejandro Díaz Candelas Farah Al Shwely Abduljabar Ignacio Antonio Gemio del Rey 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第4期1155-1164,共10页
BACKGROUND The quality-adjusted life year(QALY)is a metric that is increasingly used today in the field of health economics to evaluate the value of different medical treatments and procedures.Surgical waiting lists(S... BACKGROUND The quality-adjusted life year(QALY)is a metric that is increasingly used today in the field of health economics to evaluate the value of different medical treatments and procedures.Surgical waiting lists(SWLs)represent a pressing problem in public healthcare.The QALY measure has rarely been used in the context of surgery.It would be interesting to know how many QALYs are lost by patients on SWLs.AIM To investigate the relationship between QALYs and SWLs in a systematic review of the scientific literature.METHODS The study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement.An unlimited search was carried out in PubMed,updated on January 19,2024.Data on the following variables were investigated and analyzed:Specialty,country of study,procedure under study,scale used to measure QALYs,the use of a theoretical or real-life model,objectives of the study and items measured,the economic value assigned to the QALY in the country in question,and the results and conclusions published.RESULTS Forty-eight articles were selected for the study.No data were found regarding QALYs lost on SWLs.The specialties in which QALYs were studied the most in relation to the waiting list were urology and general surgery,with 15 articles each.The country in which the most studies of QALYs were carried out was the United States(n=21),followed by the United Kingdom(n=9)and Canada(n=7).The most studied procedure was organ transplantation(n=39),including 15 kidney,14 liver,5 heart,4 lung,and 1 intestinal.Arthroplasty(n=4),cataract surgery(n=2),bariatric surgery(n=1),mosaicplasty(n=1),and septoplasty(n=1)completed the surgical interventions included.Thirty-nine of the models used were theoretical(the most frequently applied being the Markov model,n=34),and nine were real-life.The survey used to measure quality of life in 11 articles was the European Quality of Life-5 dimensions,but in 32 articles the survey was not specified.The willingness-to-pay per QALY gained ranged from$100000 in the United States to€20000 in Spain.CONCLUSION The relationship between QALYs and SWLs has only rarely been studied in the literature.The rate of QALYs lost on SWLs has not been determined.Future research is warranted to address this issue. 展开更多
关键词 Quality-adjusted life year Waitlist Quality of life SURGERY Systematic review
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Reevaluating health metrics:Unraveling the limitations of disabilityadjusted life years as an indicator in disease burden assessment
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作者 Ariel Beresniak Dominique Bremond-Gignac +1 位作者 Danielle Dupont Gerard Duru 《World Journal of Methodology》 2025年第1期14-19,共6页
In 1993,the World Bank released a global report on the efficacy of health promotion,introducing the disability-adjusted life years(DALY)as a novel indicator.The DALY,a composite metric incorporating temporal and quali... In 1993,the World Bank released a global report on the efficacy of health promotion,introducing the disability-adjusted life years(DALY)as a novel indicator.The DALY,a composite metric incorporating temporal and qualitative data,is grounded in preferences regarding disability status.This review delineates the algorithm used to calculate the value of the proposed DALY synthetic indicator and elucidates key methodological challenges associated with its application.In contrast to the quality-adjusted life years approach,derived from multi-attribute utility theory,the DALY stands as an independent synthetic indicator that adopts the assumptions of the Time Trade Off utility technique to define Disability Weights.Claiming to rely on no mathematical or economic theory,DALY users appear to have exempted themselves from verifying whether this indicator meets the classical properties required of all indicators,notably content validity,reliability,specificity,and sensitivity.The DALY concept emerged primarily to facilitate comparisons of the health impacts of various diseases globally within the framework of the Global Burden of Disease initiative,leading to numerous publications in international literature.Despite widespread adoption,the DALY synthetic indicator has prompted significant methodological concerns since its inception,manifesting in inconsistent and non-reproducible results.Given the substantial diffusion of the DALY indicator and its critical role in health impact assessments,a reassessment is warranted.This reconsideration is imperative for enhancing the robustness and reliability of public health decisionmaking processes. 展开更多
关键词 Disability adjusted life years Cost-utility analyses Outcome research Public health Burden of disease
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Effects of Different Planting Years on Physicochemical Properties and Enzyme Activities in Soil of Rice-Cherry Tomato Rotation
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作者 Xiao Deng Chunyuan Wu +2 位作者 Yi Li Huadong Tan Jiancheng Su 《Open Journal of Ecology》 2023年第6期334-344,共11页
Crop rotation periodicity has always been one of the research focuses currently. In this study, the physicochemical properties, nutrient contents and enzyme activities were investigated in soils from rice-cherry tomat... Crop rotation periodicity has always been one of the research focuses currently. In this study, the physicochemical properties, nutrient contents and enzyme activities were investigated in soils from rice-cherry tomato rotation for one year (1a), three years (3a), five years (5a), seven years (7a) and ten years (10a), respectively. The major objective was to analyze the optimal rotation years of rice-cherry tomato from soil perspective, so as to provide theoretical basis for effectively avoiding continuous cropping obstacles of cherry tomato via studying the response characteristics of soil physicochemical properties, nutrient contents and enzyme activities to planting years of rice-cherry tomato rotation system. The results were as follows: 1) Soil pH value was increased year by year during 1a to 5a, reached the highest value 5.32 at 5a. However, soil acidity was sharply enhanced during 7a to 10a (P P •kg<sup>-1</sup> at 5a. 3) The content of soil available phosphorus was increased year by year with increasing of crop rotation years, and increased by 110% to 173% during 3a to 10a (P P P < 0.05). In conclusion, long-term single rotation pattern of rice-cherry tomato would aggravate soil acidification, prompt soil nutrient imbalance and reduce soil enzyme activity. 5a to 7a would be the appropriate rotation period for rice-cherry tomato, or else it would reduce soil quality, resulting in a new continuous cropping obstacle of cherry tomato. 展开更多
关键词 Rice-Cherry Tomato Rotation Planting years SOIL Physicochemical Properties Enzyme Activity
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Improving the Use of Insecticide-Treated Nets among Children under Five Years Old in Benin, West Africa
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作者 Emmanuel Houessou Tatchémè Filémon Tokponnon 《Advances in Infectious Diseases》 2023年第2期137-158,共22页
Background: In Benin, malaria represents the first cause of consultation and hospitalization (48% for children under 5 years old) in health units. It also accounts for 23.1% of deaths recorded in health facilities (Mo... Background: In Benin, malaria represents the first cause of consultation and hospitalization (48% for children under 5 years old) in health units. It also accounts for 23.1% of deaths recorded in health facilities (MoH, 2019). Between the two main components of vector control adopted by Benin government, the mass distribution campaigns of Insecticide-Treated Nets (ITNs) remained the only proven cost-effective way to rapidly achieve high and equitable coverage (WHO, 2017). After the fourth mass distribution campaign conducted in 2017, the Demographic and Health Survey (DHS) data indicated that the percentage of children who slept under an ITN has increased from 20% in 2006 to 70% in 2011-2012 and to 76% in 2017-2018 while the incidence of malaria (tested positive) is increasing rapidly among children under 5 years old, growing from 36.5% in 2009 to 28.8% in 2012 and then to 51.4% in 2019. This study aims to understand this contrast by identifying the origin of the increase in ITN use over time among children under five years old and the factors which determine this use. Methods: Data from the Demographic and Health Survey (DHS) conducted in Benin respectively in 2006 and in 20018 were used during the analysis, which covered 13,445 children under five years old from 2006 DHS and 12,255 children from 2017-2018 DHS. Firstly, the data were analyzed using decomposition method to highlight the origin of the increase of ITN use over time among children under five years old. Secondly, the chi-square test analysis estimated the association between ITN use and some characteristics (wealth index, maternal or caregiver education level and child age). Finally, the logistic regression model was used to identify the main factors, which influence the net use over the study period. Results: This study shows that the improvement of basic conditions is the main origin of behavior change in the use of ITNs among children under five years old. This improvement of the basic conditions consists of making ITNs available in households and informing household members about the benefits of ITN use. So, the free ITN distribution campaigns, routine distribution, awareness campaigns about the benefits of ITN use are the strategies, which increase the household capacities and knowledge, allowing household members to make their children sleep under net. The analysis also shows that region of residence, wealth index of household, household size, religion, and child age continue to determine the ITN use among children under age 5 years old and MNCP will integrate the factors in malaria prevention strategies in order to achieve universal use of ITNs. Conclusions: Although, sleeping under ITN behavior has indeed spread among children under 5 years old, policymakers and other stakeholders should design strategies to maintain and improve the current level of ITN use to reach the collective protection threshold (80% according to WHO). Therefore, to address the challenges of universal use of ITN, the study recommends expanding the routine distribution system to private sector health centers;discussing issues related to health service utilization (particularly ITN use) within a consultation framework at the communal level. In addition, collecting qualitative and quantitative data in the Oueme region will allow better understanding of all aspects of the ITN use gap among children under 5 years. 展开更多
关键词 MALARIA Long-Lasting Insecticidal Net (LLIN) Child under 5 years Old Health Policy BENIN
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The Prevalence and Risk Factors Associated with Otitis Media in Children under Five Years of Age in Mogadishu, Somalia: A Hospital-Based Cross-Sectional Study
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作者 Ismail Ali Mohamed Zakaria Ahmed Mohamed +1 位作者 Fang Ning Wang Xin 《International Journal of Otolaryngology and Head & Neck Surgery》 2023年第6期426-443,共18页
Background: Otitis media (OM) is highly prevalent and is one of the most important causes of preventable hearing loss in developing countries and it may have long-term impacts on the children. Several hospital-based c... Background: Otitis media (OM) is highly prevalent and is one of the most important causes of preventable hearing loss in developing countries and it may have long-term impacts on the children. Several hospital-based cross-sectional studies have been conducted in East African countries to assess the prevalence of OM;however, no similar studies have been conducted in Somalia. Therefore, we conducted a hospital-based cross-sectional study to identify the prevalence and the underlying risk factors of OM among children under the age of five in Mogadishu, Somalia. Methodology: A hospital-based cross-sectional study was conducted from July 2022 to November 2022 at three main hospitals in Mogadishu, Somalia. A total of 384 children aged less than 5 years were included. Parents of these children were interviewed with a questionnaire and a clinical examination was performed for each child. The Statistical Package for Social Sciences, SPSS (Version 22, IBM, Inc.), was used for the statistical analysis. Result: The prevalence of otitis media among the 384 children recruited was 31.25% (120/384). Otitis media was significantly associated with age less than one year (P = 0.006), malnutrition (P Conclusion: In summary, the present study found that otitis media was highly prevalent (31.25%) in Mogadishu, Somalia. The majority of the affected children were younger than one year. Age of the child, malnutrition, upper respiratory tract infections, feeding in lying position, and dripping something into a child’s ear were found to significantly increase the risk of developing otitis media in children. In contrast, breastfeeding for more than one year has been found to reduce the risk of developing otitis media in children. 展开更多
关键词 Otitis Media Children under Five years PREVALENCE Risk Factors
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基于智能感官和气相色谱-离子迁移谱分析贮藏年限对酱香型白酒的影响 被引量:2
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作者 王玉荣 田龙新 +4 位作者 张振东 黄利科 孔金钊 郝光飞 郭壮 《食品与发酵工业》 CAS CSCD 北大核心 2024年第14期305-313,共9页
该研究以采集自河北省邯郸市永不分梨酒业股份有限公司的第四轮次基酒为主要研究对象,基于智能感官和气相色谱-离子迁移谱(gas chromatography-ion mobility spectrometry,GC-IMS)技术,探究了储藏年限对酱香型白酒感官品质和风味特征的... 该研究以采集自河北省邯郸市永不分梨酒业股份有限公司的第四轮次基酒为主要研究对象,基于智能感官和气相色谱-离子迁移谱(gas chromatography-ion mobility spectrometry,GC-IMS)技术,探究了储藏年限对酱香型白酒感官品质和风味特征的影响。结果表明,不同贮藏年限酱香型白酒中酸酯总量和总酯含量分别在74.16~85.40 mmol/L和2.89~3.64 g/L,且随着白酒贮藏年限的增加,酒体中酸酯总量、总酯含量、鲜味、有机硫化物和萜类物质含量呈明显下降趋势,而酒体的明亮度、酸味和芳香类物质含量则明显升高。通过GC-IMS共定性了49种挥发性化合物,可以有效区分不同储藏年限酱香型白酒。筛选出18种变量投影重要性(variable importance in the projection,VIP)值>1且P<0.05的关键差异化合物,并从中挑选出6个相对气味活度值(relative odor activity value,ROAV)>1的香气化合物,其中3-甲基丁酸乙酯和2-甲基丁酸乙酯在贮藏10年的酱香型白酒中ROAV显著偏高(P<0.05),且其对白酒的明亮度、酸味、苦味、涩味、咸味和芳香风味等感官品质具有积极作用。因此,贮藏10年的酱香型白酒品质更佳,该研究为酱香型白酒选择合适的贮藏时间提供了理论依据。 展开更多
关键词 贮藏年限 酱香型白酒 感官品质 挥发性化合物
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甘薯连作障碍发生的土壤养分因素探讨 被引量:1
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作者 许仙菊 姜晓蕊 +4 位作者 陈丹艳 张永春 汪吉东 冯冰 钟月华 《中国土壤与肥料》 CAS CSCD 北大核心 2024年第4期102-107,共6页
连作障碍是甘薯种植中的一个突出问题。为了阐明甘薯连作障碍发生的原因,分别采集了5、10和15年连作甘薯及其对照土壤,分析了土壤pH、有机质、阳离子交换量、全量和有效态氮、磷、钾含量、有效态中微量元素含量,并计算了土壤氮、磷、钾... 连作障碍是甘薯种植中的一个突出问题。为了阐明甘薯连作障碍发生的原因,分别采集了5、10和15年连作甘薯及其对照土壤,分析了土壤pH、有机质、阳离子交换量、全量和有效态氮、磷、钾含量、有效态中微量元素含量,并计算了土壤氮、磷、钾之间的比值。结果表明:相比于各自对照,5年甘薯连作显著提高了土壤pH,但是10和15年连作显著降低了土壤pH;5年连作对土壤有机质含量影响较小,但是10和15年连作提高了土壤有机质含量,其中15年连作达显著水平;5年连作对土壤全氮和碱解氮含量影响较小,但是10和15年连作均显著提高了土壤全氮和碱解氮含量;5、10和15年连作均显著提高了土壤全磷和有效磷含量;不同连作年限对土壤全钾、速效钾和中微量元素(钙、镁、硫、铁、锰、铜、锌、硅)含量的影响没有明显规律;甘薯多年连作后,土壤氮/磷降低,氮/钾和磷/钾升高,导致土壤氮、磷、钾失衡,氮磷过多可能引起钾的相对缺乏,也会破坏土壤微生态体系,引起病虫害发生。甘薯是一种耐贫瘠且喜钾植物,基于上述结果,甘薯连作一般不会造成土壤肥力的降低,土壤酸化和氮磷钾养分失衡可能是造成甘薯连作障碍发生的两个主要原因。 展开更多
关键词 连作年限 甘薯 土壤养分 障碍因素 土壤酸化
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1990-2019年中国成年人归因于糖尿病的心血管疾病负担研究 被引量:1
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作者 梁栋 杨成琳 +3 位作者 林晓茹 赵洋 欧阳江 林修全 《中国全科医学》 北大核心 2024年第11期1380-1386,1394,共8页
背景在全球老龄化不断深化的背景下,慢性病患者不断增加,多病共存现象愈加严重。在普遍认知中,心血管疾病与2型糖尿病大多属于老年病,但随着居民生活节奏与饮食等行为方式的改变,很多疾病呈现年轻化趋势。现也有研究表明,与一般人群相比... 背景在全球老龄化不断深化的背景下,慢性病患者不断增加,多病共存现象愈加严重。在普遍认知中,心血管疾病与2型糖尿病大多属于老年病,但随着居民生活节奏与饮食等行为方式的改变,很多疾病呈现年轻化趋势。现也有研究表明,与一般人群相比,年轻时患糖尿病的患者的心血管疾病风险及死亡率会相对增加。目的探究1990—2019年中国成年人归因于糖尿病的心血管疾病负担情况,为共病预防提供依据。方法基于2019年全球疾病负担研究(GBD)数据,主要采用死亡率、伤残调整寿命年(DALY)率和计算获取的年估计变化百分比(EAPC)等指标评估我国心血管疾病(包括缺血性心脏病、脑卒中和外周动脉疾病3类)归因于糖尿病的疾病负担情况,并对年龄段(25~49岁、50~69岁、≥70岁)及性别进行分层分析,最后对疾病负担的时间趋势进行分析。结果中国25岁及以上人群归因于糖尿病的心血管疾病死亡数从1990年的29.805万例上升到2019年的70.034万例。男性归因于糖尿病的心血管疾病标化死亡率较1990年升高,而女性标化死亡率有所降低,且男性标化死亡率始终高于女性。2019年归因于糖尿病的心血管疾病DALY为1358.585万人年,按年龄划分的死亡率和DALY率随年龄增长而增加。女性标化DALY率下降趋势较男性明显(女性:EAPC=-0.32%,95%CI=-0.49%~-0.11%;男性:EAPC=-0.01%,95%CI=-0.26%~0.29%)。2019年归因于糖尿病的缺血性心脏病、外周动脉疾病患者3个年龄段的死亡率和DALY率较1990年大部分上升,而2019年归因于糖尿病的脑卒中患者3个年龄段的死亡率较1990年下降。1990—2019年心血管疾病中3类心血管疾病归因于糖尿病的标化DALY率占比呈波动性变化,但在2019年归因于糖尿病的3类心血管疾病标化DALY率占比均高于1990年。结论1990—2019年我国成年人归因于糖尿病的心血管疾病的死亡率和DALY率总体呈现上升趋势,人群糖尿病及心血管疾病共病风险较大,应注重在糖尿病患者中筛查心血管疾病或患心血管疾病风险高的个体,重点关注男性、高龄人群以及不良生活习惯较多的年轻人,对其进行早期的健康干预,减少共病疾病负担。 展开更多
关键词 心血管疾病 糖尿病 成年人 疾病负担 死亡率 伤残调整寿命年
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中国石化“十四五”主要勘探进展与发展战略 被引量:2
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作者 张宇 赵培荣 +5 位作者 刘士林 刘超英 程喆 陈前 陈刚 张飞燕 《中国石油勘探》 CAS CSCD 北大核心 2024年第1期14-31,共18页
在系统梳理中国石油化工股份有限公司(简称中国石化)“十四五”以来高质量勘探举措、理论技术进展及油气勘探成果的基础上,提出了油气勘探发展战略。“十四五”以来,中国石化坚定资源发展信心,大力推动高质量勘探实践,在塔里木、四川、... 在系统梳理中国石油化工股份有限公司(简称中国石化)“十四五”以来高质量勘探举措、理论技术进展及油气勘探成果的基础上,提出了油气勘探发展战略。“十四五”以来,中国石化坚定资源发展信心,大力推动高质量勘探实践,在塔里木、四川、渤海湾、准噶尔、鄂尔多斯等盆地的深层碳酸盐岩、陆相页岩油、深层页岩气、中西部碎屑岩、成熟探区隐蔽油气藏、深层煤层气等领域取得了主要勘探成果,为石油稳增长、天然气快上产夯实了储量基础。同时,发展完善了超深走滑断控缝洞型油气成藏理论、创新形成了页岩油成储成烃富集理论、深化了海相页岩气“二元富集”与致密碎屑岩油气差异富集机理认识等;攻关形成了复杂地质结构与储层结构条件下的以地震勘探、深层—超深层钻完井、超深层测录试井、水平井压裂技术等为代表的关键技术与工程工艺技术。展望未来,中国石化探区具备石油稳定发展、天然气快速发展的资源基础,勘探工作聚焦保拓矿权、勘探突破、规模增储三大核心责任,以深地工程、页岩油气示范工程、致密碎屑岩效益攻坚、常非统筹为统领,加快推进战略突破发现,落实规模增储阵地,进一步夯实上游可持续发展资源基础。 展开更多
关键词 中国石化 “十四五” 勘探成果 理论认识 勘探技术 发展潜力 发展思路 发展战略
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“黑皇”葡萄在广西南宁引种表现及一年两收栽培技术 被引量:1
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作者 时晓芳 张瑛 +5 位作者 韩佳宇 程昌富 蒋士宋 罗梅娟 李倩珍 梁海芸 《中国南方果树》 北大核心 2024年第2期201-205,共5页
为解决广西鲜食葡萄栽培品种单一化问题,促进产业结构调整,增加广西葡萄品种种类,引进“黑皇”葡萄进行种植。通过连续2年4个生长周期对其植物学特征进行观察、记录,并研究配套的一年两收栽培技术。结果表明:“黑皇”葡萄在广西南宁地... 为解决广西鲜食葡萄栽培品种单一化问题,促进产业结构调整,增加广西葡萄品种种类,引进“黑皇”葡萄进行种植。通过连续2年4个生长周期对其植物学特征进行观察、记录,并研究配套的一年两收栽培技术。结果表明:“黑皇”葡萄在广西南宁地区表现出花芽分化好且整齐,果实着色正常,品质优良,适合在广西南宁避雨栽培条件下进行一年两收栽培。 展开更多
关键词 黑皇葡萄 广西南宁 引种表现 一年两收 栽培技术
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农牧交错区不同撂荒年限对农田土壤的影响 被引量:1
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作者 黄晶 刘克思 +5 位作者 豆鹏鹏 高茜 刘程 苗正洲 任卓然 王堃 《草地学报》 CAS CSCD 北大核心 2024年第3期677-683,共7页
为研究撂荒年限对农田土壤的影响,本试验于8月植物生长旺季进行,选取未撂荒农田(CK)、撂荒7年(7a)、15年(15a)和30年(30a)的农田采集土壤样品,室内计算分析土壤理化特征的变化规律,结果表明,撂荒显著提高了土壤容重,降低了土壤孔隙度和... 为研究撂荒年限对农田土壤的影响,本试验于8月植物生长旺季进行,选取未撂荒农田(CK)、撂荒7年(7a)、15年(15a)和30年(30a)的农田采集土壤样品,室内计算分析土壤理化特征的变化规律,结果表明,撂荒显著提高了土壤容重,降低了土壤孔隙度和土壤pH。与未撂荒地对比,撂荒显著提高了土壤有机碳(Soil organic carbon,SOC)、全氮(Soil total nitrogen,TN)和全磷(Soil total phosphorus,TP)的含量。因此,长期撂荒对土壤养分状况具有显著改善作用。不同撂荒年限土壤含水量与土壤养分指标均呈显著正相关,长期撂荒下更少的蒸散耗水量减少了土壤水分的损失,使土壤养分得到了积累。本研究可为坝上农牧交错带撂荒地的合理规划提供理论支撑。 展开更多
关键词 农牧交错带 农田 撂荒年限 土壤水分 土壤理化性质 土壤养分
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作为“成年新礼”的“间隔年”:过渡仪式、认同重构与主体实践 被引量:1
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作者 李建军 王勇 《云南民族大学学报(哲学社会科学版)》 CSSCI 北大核心 2024年第3期33-41,共9页
“间隔年”(gap year)是当今社会文化变迁背景下的一种新兴行为和社会心态,具有青少年“成年新礼”的特征,而“过渡礼仪”成为其重要的过程机制。“分隔礼仪”体现的是和先前世界的隔离,其核心要义是冲破理性化世界后的自主选择。在迷... “间隔年”(gap year)是当今社会文化变迁背景下的一种新兴行为和社会心态,具有青少年“成年新礼”的特征,而“过渡礼仪”成为其重要的过程机制。“分隔礼仪”体现的是和先前世界的隔离,其核心要义是冲破理性化世界后的自主选择。在迷茫与机遇、兴奋与惆怅并存的状态下,个人层面上极具张力的重大决定与社会层面充满道德意义的新仪式促成了新的自我认同的形成。“间隔年”及青年“认同重构”已不再属于“边缘仪式”的亚文化范畴,而是当今社会文化变迁背景下应运而生的一种行为方式和社会心态,标志着新的自我认同的建构。 展开更多
关键词 “间隔年” “成年新礼” 过渡仪式 自我认同 主体实践
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国企改革三年行动收官后国企改革重点方向思路研究 被引量:2
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作者 刘方 《当代经济管理》 CSSCI 北大核心 2024年第6期53-61,共9页
国企是推进中国式现代化的核心主体,是实现中华民族伟大复兴和有效应对世界百年未有之大变局的重要力量。文章重点描述国企改革三年行动取得的主要成绩,通过三年行动破除了一批体制机制障碍,有效解决了一批长期没有解决的难题,在许多重... 国企是推进中国式现代化的核心主体,是实现中华民族伟大复兴和有效应对世界百年未有之大变局的重要力量。文章重点描述国企改革三年行动取得的主要成绩,通过三年行动破除了一批体制机制障碍,有效解决了一批长期没有解决的难题,在许多重要领域和关键环节实现重塑、重构;同时,阐述了当前国企改革存在的问题,在支撑企业核心竞争力提高和核心功能增强方面还有不足,在支撑中国式现代化建设中还存在诸多体制机制障碍;最后,提出了未来进一步推进国企改革的主要思路。研究得出,要继续通过实施更具战略性、系统性、突破性、实质性的国企改革提升行动,建设中国特色现代新国企,充分发挥在建设现代化产业体系、构建新发展格局中的科技创新、产业控制、安全支撑、国计民生、公共服务功能与作用。 展开更多
关键词 国企改革 三年行动 重点方向 思路
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宁波市热浪对寿命损失年影响的总效应及附加效应
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作者 谷少华 王爱红 +2 位作者 王永 陆蓓蓓 张丹丹 《中国卫生统计》 CSCD 北大核心 2024年第3期404-408,413,共6页
目的评估宁波市热浪对寿命损失年(YLL)影响的总效应及附加效应。方法收集2013—2019年宁波市死亡、人口、气象和空气质量监测资料,计算得到每日YLL率;根据日最高气温的百分位数和持续时间定义15种热浪类型,利用时间序列方法结合分布滞... 目的评估宁波市热浪对寿命损失年(YLL)影响的总效应及附加效应。方法收集2013—2019年宁波市死亡、人口、气象和空气质量监测资料,计算得到每日YLL率;根据日最高气温的百分位数和持续时间定义15种热浪类型,利用时间序列方法结合分布滞后非线性模型评估热浪对人群YLL率影响的总效应及附加效应,并按照性别和年龄(<65岁、≥65岁)进行分层分析。结果研究期间宁波市人群总YLL率为(19.74±3.14)人年/10万,热浪期的总YLL率均高于非热浪期(P<0.05)。随着热浪强度增加和持续时间延长,热浪的总效应均呈上升趋势。当热浪定义为日最高气温≥P97.5(37.2℃)且持续时间≥2d时,热浪累积10 d(Lag0-10 d)的总效应最大,总YLL率增加3.77(95%CI:2.25,5.29)人年/10万。热浪对男性和老年人影响的总效应高于女性和低年龄人群。仅部分热浪类型对男性和老年人YLL率影响的附加效应有统计学意义(P<0.05)。结论热浪导致宁波市人群YLL率增加,且对男性和老年人的影响更大;热浪的附加效应可能仅在男性和老年人等敏感人群中出现。 展开更多
关键词 热浪 附加效应 寿命损失年
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