Functional diarrhea(FDr)accounts for a relatively high proportion of digestive diseases.It is an infection that is not accompanied by abdominal pain and shows negative results in laboratory tests for bacteria and viru...Functional diarrhea(FDr)accounts for a relatively high proportion of digestive diseases.It is an infection that is not accompanied by abdominal pain and shows negative results in laboratory tests for bacteria and viruses.The main symptoms are persistent or recurrent discharge of watery and soft stools.The course of the disease is prolonged and recurring,and the treatment cost is higher and greatly affects the patient’s daily life.The incidence rate has a gradual increase in the trend.Its pathogenesis is complex where Western medicine is mostly used in symptomatic drug treatment.The treatment can be fast-acting and effective in relieving diarrhea.However,the long-term use of Western medicine poses a high risk in terms of side effects and a high chance of recurring upon stopping medication.At the same time,some diarrhea patients show the existence of drug-resistant strains of bacteria,and the overall efficacy of the drug is limited.Chinese medicine is mild and able to provide excellent treatment of diarrhea.With its lower price and cost,most families can afford it.Fengliang Tian,director of traditional Chinese medicine,implemented the“needle and medicine”method,which combines medicine and acupuncture,involving the usage of Jianpi Yishen Sechang Decoction and acupuncture in the treatment of functional diarrhea.The method has a low price,fewer side effects,is easy to accept,and can significantly reduce the recurrence rate with high efficacy.The study would like to share the clinical thinking and cases as follows to provide ideas and methods for the treatment of functional diarrhea by traditional Chinese medicine.展开更多
目的:探究健脾益肾通络汤治疗IgA肾病效果及对患者肾功能、炎症因子的影响。方法:选取IgA肾病患者98例,采用随机掷硬币法分为两组。西药组常规西药治疗,49例,联合组在西药组的基础上服用健脾益肾通络汤,49例。治疗3个月后比较两组疗效...目的:探究健脾益肾通络汤治疗IgA肾病效果及对患者肾功能、炎症因子的影响。方法:选取IgA肾病患者98例,采用随机掷硬币法分为两组。西药组常规西药治疗,49例,联合组在西药组的基础上服用健脾益肾通络汤,49例。治疗3个月后比较两组疗效、中医证候积分、肾功能[24 h尿蛋白定量(24 h UTP)、血清血肌酐(SCr)、血尿素氮(BUN)、白蛋白(ALB)]、炎症因子[肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)、干扰素-γ(INF-γ)]和不良反应。结果:治疗总有效率联合组为95.92%,高于西药组的81.63%(P<0.05)。治疗后两组的中医证候积分、24 h UTP及血清SCr、BUN、IL-6、TNF-α均降低,且联合组均低于西药组,差异有统计学意义(均P<0.05)。治疗后,两组患者血清ALB、INF-γ均升高,且联合组高于西药组,差异有统计学意义(均P<0.05)。不良反应总发生率西药组为10.20%,联合组为14.29%,两组比较差异无统计学意义(P>0.05)。结论:健脾益肾通络汤治疗IgA肾病疗效较好,可以有效减轻患者临床症状,改善肾功能,降低炎症反应,安全性较高。展开更多
基金Wang Renqiang Famous Elderly Chinese Medicine Experts Inheritance Workshop Project(Project No.:cqzyymzygzs-018)Chengdu University of Traditional Chinese Medicine Apricot Grove Scholars Discipline Talent Scientific Research Enhancement Program(Project No.:YYZX2021079)Project of National Natural Science Foundation of China(Project No.:81904175)。
文摘Functional diarrhea(FDr)accounts for a relatively high proportion of digestive diseases.It is an infection that is not accompanied by abdominal pain and shows negative results in laboratory tests for bacteria and viruses.The main symptoms are persistent or recurrent discharge of watery and soft stools.The course of the disease is prolonged and recurring,and the treatment cost is higher and greatly affects the patient’s daily life.The incidence rate has a gradual increase in the trend.Its pathogenesis is complex where Western medicine is mostly used in symptomatic drug treatment.The treatment can be fast-acting and effective in relieving diarrhea.However,the long-term use of Western medicine poses a high risk in terms of side effects and a high chance of recurring upon stopping medication.At the same time,some diarrhea patients show the existence of drug-resistant strains of bacteria,and the overall efficacy of the drug is limited.Chinese medicine is mild and able to provide excellent treatment of diarrhea.With its lower price and cost,most families can afford it.Fengliang Tian,director of traditional Chinese medicine,implemented the“needle and medicine”method,which combines medicine and acupuncture,involving the usage of Jianpi Yishen Sechang Decoction and acupuncture in the treatment of functional diarrhea.The method has a low price,fewer side effects,is easy to accept,and can significantly reduce the recurrence rate with high efficacy.The study would like to share the clinical thinking and cases as follows to provide ideas and methods for the treatment of functional diarrhea by traditional Chinese medicine.
文摘目的:探究健脾益肾通络汤治疗IgA肾病效果及对患者肾功能、炎症因子的影响。方法:选取IgA肾病患者98例,采用随机掷硬币法分为两组。西药组常规西药治疗,49例,联合组在西药组的基础上服用健脾益肾通络汤,49例。治疗3个月后比较两组疗效、中医证候积分、肾功能[24 h尿蛋白定量(24 h UTP)、血清血肌酐(SCr)、血尿素氮(BUN)、白蛋白(ALB)]、炎症因子[肿瘤坏死因子α(TNF-α)、白细胞介素6(IL-6)、干扰素-γ(INF-γ)]和不良反应。结果:治疗总有效率联合组为95.92%,高于西药组的81.63%(P<0.05)。治疗后两组的中医证候积分、24 h UTP及血清SCr、BUN、IL-6、TNF-α均降低,且联合组均低于西药组,差异有统计学意义(均P<0.05)。治疗后,两组患者血清ALB、INF-γ均升高,且联合组高于西药组,差异有统计学意义(均P<0.05)。不良反应总发生率西药组为10.20%,联合组为14.29%,两组比较差异无统计学意义(P>0.05)。结论:健脾益肾通络汤治疗IgA肾病疗效较好,可以有效减轻患者临床症状,改善肾功能,降低炎症反应,安全性较高。
