Environmental exposure to heavy metals has been linked to a wide range of human health hazards. We detected the levels of 15 metals in urine samples from 500 representative sub-samples in an ongoing occupational cohor...Environmental exposure to heavy metals has been linked to a wide range of human health hazards. We detected the levels of 15 metals in urine samples from 500 representative sub-samples in an ongoing occupational cohort study （Jinchang Cohort） to directly evaluate metal exposure levels. Fifteen metals, namely As, Ba, Be, Cd, Cs, Cr, Co, Cu, Pb, Mn, Ni, Se, TI, U, and Zn, were detected by inductively coupled plasma quadruple mass spectrometry. The results showed that median creatinine adjustment and geometric mean urinary metal levels were higher in the heavy metal-exposed group, except Se and Zn, than other reported general or occupational populations. Further studies should address the effects of heavy metals on human health.展开更多
Nickel is an essential trace metal used in the occupational setting, resulting in both occupational and nonoccupational exposures to individuals at varying levels. Exposure to nickel has been associated with several t...Nickel is an essential trace metal used in the occupational setting, resulting in both occupational and nonoccupational exposures to individuals at varying levels. Exposure to nickel has been associated with several toxicities and the International Agency for Research on Cancer has concluded that there is sufficient evidence in humans associating exposure to nickel compounds with risk of lung cancer and sinonasal cancer. This study confirmed a significant excess of mortality from diseases of the lung including silicosis, lung cancer, and cor pulmonale among workers involved in nickel mining or smelting in China.展开更多
基金supported by Project of Employees Health Status and Disease Burden Trend Study in Jinchua Nonferrous Metals Corporation,Grant JKB20120013Fogarty training grants D43TW 008323and D43TW 007864-01 from the US National Institutes of Health
文摘Environmental exposure to heavy metals has been linked to a wide range of human health hazards. We detected the levels of 15 metals in urine samples from 500 representative sub-samples in an ongoing occupational cohort study （Jinchang Cohort） to directly evaluate metal exposure levels. Fifteen metals, namely As, Ba, Be, Cd, Cs, Cr, Co, Cu, Pb, Mn, Ni, Se, TI, U, and Zn, were detected by inductively coupled plasma quadruple mass spectrometry. The results showed that median creatinine adjustment and geometric mean urinary metal levels were higher in the heavy metal-exposed group, except Se and Zn, than other reported general or occupational populations. Further studies should address the effects of heavy metals on human health.
文摘Nickel is an essential trace metal used in the occupational setting, resulting in both occupational and nonoccupational exposures to individuals at varying levels. Exposure to nickel has been associated with several toxicities and the International Agency for Research on Cancer has concluded that there is sufficient evidence in humans associating exposure to nickel compounds with risk of lung cancer and sinonasal cancer. This study confirmed a significant excess of mortality from diseases of the lung including silicosis, lung cancer, and cor pulmonale among workers involved in nickel mining or smelting in China.
