If you didn＇t know by now, Santa has a soft spot for China. From early November, the plastic cut outs of his rosy cheeks,piercing blue eyes and frothy beard watch you from every doorway, window and shop front. Some h...If you didn＇t know by now, Santa has a soft spot for China. From early November, the plastic cut outs of his rosy cheeks,piercing blue eyes and frothy beard watch you from every doorway, window and shop front. Some have even remained posted from the previous year. Christmas decorations become the most competitive game in town, with no self-respecting business wanting to be left behind breathing in tinsel dust.展开更多
目的建立液相色谱-串联质谱法同时测定静灵口服液中盐酸小檗碱、远志口山酮Ⅲ、3,6′-二芥子酰基蔗糖、盐酸黄柏碱、芒果苷、细叶远志皂苷、五味子醇甲和特女贞苷8种主要成分的1/4含量。方法采用BEH C 18色谱柱(2.1×50 mm,1.7μm)...目的建立液相色谱-串联质谱法同时测定静灵口服液中盐酸小檗碱、远志口山酮Ⅲ、3,6′-二芥子酰基蔗糖、盐酸黄柏碱、芒果苷、细叶远志皂苷、五味子醇甲和特女贞苷8种主要成分的1/4含量。方法采用BEH C 18色谱柱(2.1×50 mm,1.7μm),流动相A为乙腈,流动相B为0.1%甲酸水溶液,柱温40℃,流速0.3 mL/min,梯度洗脱。质谱条件为电喷雾(ESI)离子源,正、负离子多反应离子监测(MRM)用于定量分析。结果盐酸小檗碱、远志口山酮Ⅲ、3,6′-二芥子酰基蔗糖、盐酸黄柏碱、芒果苷、细叶远志皂苷、五味子醇甲和特女贞苷分别在0.05~10、0.02~1、0.02~1、0.02~1、0.001~1、0.01~1、0.02~1、0.02~1μg/mL线性关系良好,平均加样回收率在98.4%~103.2%范围内,RSD≤4.34%。6批样品中上述8种成分的含量依次为22.39~29.43、2.75~8.85、7.58~9.58、10.08~20.11、0.09~0.61、9.31~11.71、0.55~5.39、6.45~28.08μg/mL。结论该方法操作简单、分离效果好、灵敏度高,具有良好的重复性和准确性,可以为静灵口服液的质量控制提供重要参考。展开更多
文摘If you didn＇t know by now, Santa has a soft spot for China. From early November, the plastic cut outs of his rosy cheeks,piercing blue eyes and frothy beard watch you from every doorway, window and shop front. Some have even remained posted from the previous year. Christmas decorations become the most competitive game in town, with no self-respecting business wanting to be left behind breathing in tinsel dust.
文摘目的建立液相色谱-串联质谱法同时测定静灵口服液中盐酸小檗碱、远志口山酮Ⅲ、3,6′-二芥子酰基蔗糖、盐酸黄柏碱、芒果苷、细叶远志皂苷、五味子醇甲和特女贞苷8种主要成分的1/4含量。方法采用BEH C 18色谱柱(2.1×50 mm,1.7μm),流动相A为乙腈,流动相B为0.1%甲酸水溶液,柱温40℃,流速0.3 mL/min,梯度洗脱。质谱条件为电喷雾(ESI)离子源,正、负离子多反应离子监测(MRM)用于定量分析。结果盐酸小檗碱、远志口山酮Ⅲ、3,6′-二芥子酰基蔗糖、盐酸黄柏碱、芒果苷、细叶远志皂苷、五味子醇甲和特女贞苷分别在0.05~10、0.02~1、0.02~1、0.02~1、0.001~1、0.01~1、0.02~1、0.02~1μg/mL线性关系良好,平均加样回收率在98.4%~103.2%范围内,RSD≤4.34%。6批样品中上述8种成分的含量依次为22.39~29.43、2.75~8.85、7.58~9.58、10.08~20.11、0.09~0.61、9.31~11.71、0.55~5.39、6.45~28.08μg/mL。结论该方法操作简单、分离效果好、灵敏度高,具有良好的重复性和准确性,可以为静灵口服液的质量控制提供重要参考。
