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Preli minary Study on Treat ment of Partial Androgen Deficiencyin Aging Males with Jingui Shenqi Pill (金匮肾气丸) 被引量:10
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作者 CHE Wen-jun(车文骏) +7 位作者 HE Xiao-zhou(何小舟) JIANG Jian-pin(姜建平) CAI Wen-yuan(蔡文元) XIE Si-jie(解斯杰) 《Chinese Journal of Integrated Traditional and Western Medicine》 2005年第4期300-302,共3页
Objective: To observe the efficacy and safety of Jingui Shengqi Pill (金匮肾气丸, JSP) in treating partial androgen deficiency in aging males (PADAM), and to explore the new approach in improving the quality of l... Objective: To observe the efficacy and safety of Jingui Shengqi Pill (金匮肾气丸, JSP) in treating partial androgen deficiency in aging males (PADAM), and to explore the new approach in improving the quality of life in PADAM patients. Methods: Forty patients with PADAM were treated with JSP, the efficacy was evaluated with international index of erectile function (IIEF) scoring, PADAM questionnaire scoring, hormone, prostatic specific antigen (PSA), etc., and the data before treatment were compared with those after treatment in the same group. Results: After 3 months of treatment, PADAM scoring and IIEF scoring were all significantly improved. Symptoms regarding physical ability, vasomotion, and psychical and mental condition all got improved more markedly than symptoms regarding sexual hypofunction. The serum level of testosterone was 3.85±0.36 before treatment and 5.02±0.83 after treatmnet (P〈0.05); luteinizing hormone of 7.33±2.14 and 4.84±1.43 (P〈0.01), follicule-stimulating hormone of 10.22±4.48 and 6.47±3.28 (P〈0.01), respectively. The level of PSA failed to change significantly (1.94±0.55 and 2.06±0.47, P〉0.05). Conclusion: JSP is effective and safe in treating PADAM, the mechanism of it is different from supplementing extrinsic androgen. It may have produced the effect by means of favorably regulating the condition of sex hormone to improve the balance of pituitary-sex gland axis, so it has more extensive clinical application. 展开更多
关键词 jingui shenqi Pill partial androgen deficiency in aging male HORMONE
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