Several bisabolane sesquiterpenes,（±）-curcumene,（±）-curcuphenol,（±）-curcudiol and（±）-curcuhydroquinone,have been synthesized in racemic form and fully characterized.The salient characterist...Several bisabolane sesquiterpenes,（±）-curcumene,（±）-curcuphenol,（±）-curcudiol and（±）-curcuhydroquinone,have been synthesized in racemic form and fully characterized.The salient characteristic of our approach is that a Johnson-Claisen arrangement was involved as a key step.展开更多
An asymmetric total synthesis of(+)-21-epi-eburnamonine has been achieved.Key features of the synthesis include a visible-light photocatalytic intra-/intramolecular radical cascade reaction to assemble the tetracyclic...An asymmetric total synthesis of(+)-21-epi-eburnamonine has been achieved.Key features of the synthesis include a visible-light photocatalytic intra-/intramolecular radical cascade reaction to assemble the tetracyclic ABCD ring system,and a highly diastereoselective Johnson-Claisen rearrangement to establish the C20 all-carbon quaternary stereocenter.展开更多
基金Financial support from Program for Excellent Young Talents in Northwest A&F University(No.2111020712) as well as the National Natural Science Foundation of China(No.20802058) is greatly appreciated.
文摘Several bisabolane sesquiterpenes,（±）-curcumene,（±）-curcuphenol,（±）-curcudiol and（±）-curcuhydroquinone,have been synthesized in racemic form and fully characterized.The salient characteristic of our approach is that a Johnson-Claisen arrangement was involved as a key step.
基金surpport from National Natural Science Foundation of China(21921002 and 21991114)National Science and Technology Major Projects for“Major New Drugs Innovation and Development”(2018ZX09711003-015 and 2018ZX09711001-005-004).
文摘An asymmetric total synthesis of(+)-21-epi-eburnamonine has been achieved.Key features of the synthesis include a visible-light photocatalytic intra-/intramolecular radical cascade reaction to assemble the tetracyclic ABCD ring system,and a highly diastereoselective Johnson-Claisen rearrangement to establish the C20 all-carbon quaternary stereocenter.
