Antikaon condensation and kaon and antikaon production in protoneutron stars are investigated in a chiral hadronic model (also referred to as the FST model in this paper). The effects of neutrino trapping on protone...Antikaon condensation and kaon and antikaon production in protoneutron stars are investigated in a chiral hadronic model (also referred to as the FST model in this paper). The effects of neutrino trapping on protoneutron stars are analyzed systematically. It is shown that neutrino trapping makes the critical density of K^- condensation delay to higher density and fifo condensation not occur. The equation of state (EOS) of (proto)neutron star matter with neutrino trapping is stiffer than that without neutrino trapping. As a result, the maximum masses of (proto)neutron stars with neutrino trapping are larger than those without neutrino trapping. If hyperons are taken into account, antikaon does not form a condensate in (proto)neutron stars. Meanwhile, the corresponding EOS becomes much softer, and the maximum masses of (proto)neutron stars are smaller than those without hyprons. Finally, our results illustrate that the Q values for K^+ and K^- production in (proto)neutron stars are not sensitive to neutrino trapping and inclusion of hyperons.展开更多
AIM: To observe the effect of resveratrol on nuclear factor Kappa-B (NF-κB) activation and the inflammatory response in sodium taurocholate-induced pancreatitis in rats. METHODS: Seventy-two male SD rats were randoml...AIM: To observe the effect of resveratrol on nuclear factor Kappa-B (NF-κB) activation and the inflammatory response in sodium taurocholate-induced pancreatitis in rats. METHODS: Seventy-two male SD rats were randomly divided into three groups: sham operation group (control), severe acute pancreatitis (SAP) group, and severe acute pancreatitis group treated with resveratrol (RES). A SAP model was established by injecting 4% sodium taurocholate 1 mL/kg through puncturing the pancreatic duct. In Res group, Res was given at 30 mg/kg b.m. intraperitoneally after the SAP model was successfully established. Eight animals from each group were sacrificed at 3, 6 and 12 h after modeling. The expression of NF-κB activation of pancreas was detected by irnmunohistochemical staining, whereas the levels of TNF-α and IL-8 in pancreatic tissues were estimated by radioimrnunoassay. The pathological changes of pancreas and lungs were examined microscopically. RESULTS: Much less hyperemia, edema, dust-colored necrotic focus and soaps were noticed in pancreas in RES group than in SAP group. In RES group, hemorrhage, exudates and infiltration of inflammatory cells in pancreas and interstitial edema, destruction of alveolar wall in lung were significantly less than in SAP group. In the SAP group, the activation of NF-κB in pancreatic tissues was enhanced significantly at any measure point compared with control group (64.23±10.72% vs 2.56±0.65%, 55.86±11.34% vs 2.32±0.42%, 36.23±2.30% vs 2.40±0.36%,P<0.01), TNF-α, IL-8 were also increased and reached their peak at 6 h and then declined. The activation of NF-κB and the levels of TNF-α and IL-8 in RES group were significantly lower than those in SAP group (P<0.01): activation (52.63±9.45% vs 64.23±10.72%, 40.52±8.40% vs 55.86±11.34%, 29.83±5.37% vs 36.23±2.30%), TNF-α (132.76±15.68 pg/mL vs 158.36±12.58 pg/mL, 220.32±23.57 pg/mL vs 247.67± 11.62 pg/mL, 175.68±18.43 pg/mL vs 197.35±12.57 pg/mL) and IL-8 (0.62±0.21 μg/L vs 0.83±0.10 μg/L, 1.10±0.124 μg/L vs1.32±0.18 μg/L, 0.98±0.16 μg/L vs 1.27±0.23μg/L). CONCLUSION: The activation of NF-KB is involved in the inflammatory response of rats with SAP. Resveratrol could effectively inhibit the expression of NF-κB activation, alleviate the severity of SAP through its anti-inflammatory effects and regulate the inflammatory mediators.展开更多
Cross sections for K-shell ionization have been measured at electron energies of 0.1-0.40 MeV for Cu and Sn, and of 0.30MeV for Ag. The present results have been compared with theoretical calculations and previously r...Cross sections for K-shell ionization have been measured at electron energies of 0.1-0.40 MeV for Cu and Sn, and of 0.30MeV for Ag. The present results have been compared with theoretical calculations and previously reported experimental values.展开更多
The energy spectra of reflected electrons from the substrates of targets have been calculated by the bipartition model of electron transport, the contributions of the inner shen ionization events produced by the refle...The energy spectra of reflected electrons from the substrates of targets have been calculated by the bipartition model of electron transport, the contributions of the inner shen ionization events produced by the reflected electrons from the substrates in the targets to the x-ray counting in a St(Li) detector have been estimated. It has been confirmed that, by such correction to the measured data, the experimental results of inner shell ionization cross sections by electron impact with fine precision may be obtained under the condition of thick substrate.展开更多
基金The project supported by National Natural Science Foundation of China under Grant Nos. 10575005, 10275002, 10435080, 10425521, and 10135030, the Key Project of the Ministry of Education under Grant No. 305001, and the CAS Knowledge Innovation Project under Grant No. KJcx2-sw-No2 0ne of authors (Hua Guo) is indebted to Dr. S. Pal since we can check our numerical results by using his code, and also thank Dr. Z.W. Lin for his kind help.
文摘Antikaon condensation and kaon and antikaon production in protoneutron stars are investigated in a chiral hadronic model (also referred to as the FST model in this paper). The effects of neutrino trapping on protoneutron stars are analyzed systematically. It is shown that neutrino trapping makes the critical density of K^- condensation delay to higher density and fifo condensation not occur. The equation of state (EOS) of (proto)neutron star matter with neutrino trapping is stiffer than that without neutrino trapping. As a result, the maximum masses of (proto)neutron stars with neutrino trapping are larger than those without neutrino trapping. If hyperons are taken into account, antikaon does not form a condensate in (proto)neutron stars. Meanwhile, the corresponding EOS becomes much softer, and the maximum masses of (proto)neutron stars are smaller than those without hyprons. Finally, our results illustrate that the Q values for K^+ and K^- production in (proto)neutron stars are not sensitive to neutrino trapping and inclusion of hyperons.
基金Supported by the National Natural Science Foundation of China, No.30371398
文摘AIM: To observe the effect of resveratrol on nuclear factor Kappa-B (NF-κB) activation and the inflammatory response in sodium taurocholate-induced pancreatitis in rats. METHODS: Seventy-two male SD rats were randomly divided into three groups: sham operation group (control), severe acute pancreatitis (SAP) group, and severe acute pancreatitis group treated with resveratrol (RES). A SAP model was established by injecting 4% sodium taurocholate 1 mL/kg through puncturing the pancreatic duct. In Res group, Res was given at 30 mg/kg b.m. intraperitoneally after the SAP model was successfully established. Eight animals from each group were sacrificed at 3, 6 and 12 h after modeling. The expression of NF-κB activation of pancreas was detected by irnmunohistochemical staining, whereas the levels of TNF-α and IL-8 in pancreatic tissues were estimated by radioimrnunoassay. The pathological changes of pancreas and lungs were examined microscopically. RESULTS: Much less hyperemia, edema, dust-colored necrotic focus and soaps were noticed in pancreas in RES group than in SAP group. In RES group, hemorrhage, exudates and infiltration of inflammatory cells in pancreas and interstitial edema, destruction of alveolar wall in lung were significantly less than in SAP group. In the SAP group, the activation of NF-κB in pancreatic tissues was enhanced significantly at any measure point compared with control group (64.23±10.72% vs 2.56±0.65%, 55.86±11.34% vs 2.32±0.42%, 36.23±2.30% vs 2.40±0.36%,P<0.01), TNF-α, IL-8 were also increased and reached their peak at 6 h and then declined. The activation of NF-κB and the levels of TNF-α and IL-8 in RES group were significantly lower than those in SAP group (P<0.01): activation (52.63±9.45% vs 64.23±10.72%, 40.52±8.40% vs 55.86±11.34%, 29.83±5.37% vs 36.23±2.30%), TNF-α (132.76±15.68 pg/mL vs 158.36±12.58 pg/mL, 220.32±23.57 pg/mL vs 247.67± 11.62 pg/mL, 175.68±18.43 pg/mL vs 197.35±12.57 pg/mL) and IL-8 (0.62±0.21 μg/L vs 0.83±0.10 μg/L, 1.10±0.124 μg/L vs1.32±0.18 μg/L, 0.98±0.16 μg/L vs 1.27±0.23μg/L). CONCLUSION: The activation of NF-KB is involved in the inflammatory response of rats with SAP. Resveratrol could effectively inhibit the expression of NF-κB activation, alleviate the severity of SAP through its anti-inflammatory effects and regulate the inflammatory mediators.
文摘Cross sections for K-shell ionization have been measured at electron energies of 0.1-0.40 MeV for Cu and Sn, and of 0.30MeV for Ag. The present results have been compared with theoretical calculations and previously reported experimental values.
文摘The energy spectra of reflected electrons from the substrates of targets have been calculated by the bipartition model of electron transport, the contributions of the inner shen ionization events produced by the reflected electrons from the substrates in the targets to the x-ray counting in a St(Li) detector have been estimated. It has been confirmed that, by such correction to the measured data, the experimental results of inner shell ionization cross sections by electron impact with fine precision may be obtained under the condition of thick substrate.