Observation of therapeutic effects of point application at Shenque(CV 8)plus moxa-salt hot compress for prevention of gastrointestinal adverse reactions after chemotherapy for non-Hodgkin Iymphoma

Objective:To observe the clinical efficacy of point application with De Huang(Rhizome Rhei Crude)powder at Shenque(CV 8)plus moxa-salt hot compress on the umbilicus for preventing gastrointestinal adverse reactions after chemotherapy for non-Hodgkin lymphoma(NHL).Methods:A total of 60 cases with NHL under chemotherapy were divided into two groups by hospitalization order,with 30 cases in each group.The control group was treated with routine nursing and the observation group was additionally given point application with Da Hueng(Rhizome Rhei Crude)powder plus moxa-salt hot compress on the umbilicus,to compare the effect in preventing gastrointestinal adverse reactions after chemotherapy between the two groups.Results:The occurrence rates of constipation,nausea,vomiting and poor appetite on the second day and fifth day after chemotherapy were obviously lower in the observation group than those in the control group,with statistically significant differences between the two groups(all P〈0.05).Conclusion;The point application with De Hueng(Rhizome Rhei Crude)powder at Shenque(CV 8)plus maxa-salt hot compress on the umbilicus can produce more significant efficacy in preventing the gastrointestinal adverse reactions after chemotherapy for NHL than routine nursing.Moreover,it is simple and easy to be used and popularized.

Acupoint Sticking at Shenque(CV 8) with Ginger-prepared Ban Xia(Rhizoma Pinelliae) for Nausea and Vomiting Induced by Amifostine

Objective： To observe the treatment effect of acupoint sticking at Shenque （CV 8） with ginger-preparedBan Xia （Rhizoma Pinelliae） on nausea and vomiting induced by Amifostine for myelodysplastic syndromes （MDS）. Methods： Totally 124 eligible subjects intervened by Amifostine were randomized into 2 groups by the visiting order,an observation group and a control group,62 in each group. The control group was intervened by conventional treatment, while the observation group was by acupoint sticking at Shenque （CV 8） with ginger-preparedBan Xia （Rhizoma Pinelliae） in addition to the same conventional treatment. The occurrence rate of nausea and vomiting in the two groups were observed. Results： After intervention, the occurrence rate of nausea and vomiting in the observation group was significantly lower than that in the control group （P＆lt;0.01）. Conclusion： Acupoint sticking at Shenque （CV 8） with ginger-prepared Ban Xia （Rhizoma Pinelliae）can produce a content effect on nausea and vomiting induced by Amifostine for MDS.

Effect of acupoint sticking at Shenque （CV 8） for preventing spleen-stomach disharmony caused by venous analgesia pump

Objective： To observe the clinical effect of acupoint sticking of Chinese medicine at Shenque （CV 8） for preventing spleenstomach disharmony caused by venous analgesia pump. Methods： A total of 120 post-surgery patients using venous analgesia pump and also conforming to the inclusion criteria were randomized into 2 groups by the random number table. There were 58 patients in the control group who received conventional post-surgery nursing care, and there were 62 patients in the treatment group who received acupoint sticking at Shenque （CV 8） on the basis of conventional nursing care. After treatment, the incidences of postoperative nausea and vomiting, and abdominal bloating were measured. Results： The total incidence of nausea, vomiting and abdominal bloating in the treatment group was 11.3%, versus 39.7% in the control group, and the difference of the incidence between the two groups showed a statistical significance （P〈0.05）. In comparison of the severity of spleen-stomach dishormony which happened during 72 h after surgery, cases in the treatment group showed lower severity than those in the control group （P〈0.05）. Conclusion： Acupoint sticking at Shenque （CV 8） can effectively prevent spleen-stomach disharmony caused by venous analgesia pump, which will alleviate sufferings of the patients.

Effect of moxibustion at Shenque （CV 8） on free radical metabolism in rat＇s hippocampus after different degrees of exhaustive exercise

Objective： To investigate the effect of moxibustion at Shenque （CV 8） on free radical metabolism in rat＇s hippocampus after different degrees of exhaustive exercise. Methods： A total of 72 male Sprague-Dawley （SD） rats were randomly divided into a normal group （n=8）, a model group （n=32） and a moxibustion group （n=32）. According to the times of modeling or treatment, the model group was further randomly divided into different subgroups of a 1-time model subgroup, a 4-time model subgroup, a 7-time model subgroup and a 10-time model subgroup （n=8）; the moxibustion group was also further randomly divided into different subgroups of a 1-time moxibustion subgroup, a 4-time moxibustion subgroup, a 7-time moxibustion subgroup and a 10-time moxibustion subgroup （n=8）. Rats in both model and moxibustion subgroups were subjected to establishing the swimming exhaustive model. Rats in each moxibustion subgroup received mild moxibustion at Shenque （CV 8） for 15 min immediately after modeling, once every other day. The concentration of malic dialdehyde （MDA）, as well as the activities of superoxide dismutase （SOD）, glutathione peroxidase （GSH-Px） and total antioxidant capacity （T-AOC） in rat＇s hippocampus in each group were detected 24 h after the exhaustive exercise. Results： Compared with the 1-time model subgroup, the exhaustive swimming time of rats was significantly prolonged in the 4-time model subgroup （P〈0.01）, while it was significantly shortened in the 7-time and 10-time model subgroups （both P〈0.01）. Compared with the matched model subgroup, the exhaustive swimming time of rats in the 7-time and 10-time moxibustion subgroups was significantly prolonged （both P〈0.01）. Compared with the normal group, the MDA concentration was increased significantly （P〈0.01）, and the activities stress response of SOD and T-AOC were increased in the 1-time model subgroup （both P〈0.05）; the MDA concentration was increased （all P〈0.01）, and the activities of SOD, GSH-Px and T-AOC were decreased differently （P〈0.05 or P〈0.01） in the 4-time, 7-time and 10-time model subgroups. Compared with the matched model subgroup, the concentration of MDA was significantly reduced （P〈0.05 or P〈0.01）, and the activities of SOD, GSH-Px and T-AOC were significantly increased in the 4-time, 7-time and 10-time moxibustion subgroups （all P〈0.01）. Conclusion： Moxibustion at Shenque （CV 8） can improve the fatigue status of the body after long-term exhaustive exercise by regulating free radical metabolism in rat＇s hippocampus. To some extent, this provides an experimental basis for moxibustion at Shenque （CV 8） against exercise-induced fatigue.

Experimental study on the effect of moxibustion at Shenque(CV 8) for long-term exercise-induced fatigue

Objective:To investigate the effect of moxibustion at Shenque(CV 8)on fatigue in rats with chronic exercise-induced exhaustion.Methods:Thirty male Sprague-Dawley(SD)rats were randomly divided into a blank group,a model group and a moxibustion group,10 rats in each group.Except rats in the blank group,the remaining rats were subjected to create long-term exhaustion models by repeated swimming.After successful modeling,rats in the moxibustion group received mild moxibustion at Shenque(CV 8)for 15 min,once every other day with a total of 10 times.Rats in the model group and the blank group did not receive moxibustion.At the end of the treatment,the exhausted times,and the body weight of rats before and after the experiment were compared among groups.The levels of blood malondialdehyde(MDA)and urea nitrogen(BUN),as well as the activities of aspartate transarninase(AST),alanine aminotransferase(ALT)and lactate dehydrogenase(LDH)were also measured by the automatic biochemical analyzer,24 h after the exhausting excise.Results:The 10 th swimming time was significantly longer in the moxibustion group than that in the model group(P〈0.01).The increase rate of the body weight was lower in the rats of the moxibustion group than that in the model group before the 7 th and the 10 th exhausting excise(P〈0.05,P〈0.01).The levels of serum MDA and BUN,as well as the activities of AST,ALT and LDH in the model group were higher than those in the blank group(all P〈0.01).The levels of serum MDA and BUN,as well as the activities of AST,ALT and LDH in the moxibustion group were lower than those in the model group(P〈0.01).Conclusion:Moxibustion at Shenque(CV 8)can decrease the serum levels of MDA and BUN,as well as activities of AST,ALT and LDH in the long-term fatigue rats,thus to improve the symptoms of fatigue.

Effect of moxibustion at Shenque (CV8) on immune system in rats with different degrees of exhaustive exercise

Objective: To investigate the effect of moxibustion at Shenque (CV8) on the immune system in rats with different levels of exhaustive exercise. Methods: Fifty-six male Sprague-Dawley (SD) rats were randomly divided into a blank group (n=8), an exhaustive group (n=24), and a moxibustion group (n=24). The exhaustive group was randomly divided into a 1-time exhaustive group, a 4-time exhaustive group and a 7-time exhaustive group, with 8 rats in each group. According to the treatment time, the moxibustion group was randomly divided into a 1-time moxibustion group, a 4-time moxibustion group and a 7-time moxibustion group, with 8 rats in each group. Rats in the exhaustive groups and the moxibustion groups were subjected to replicating the exhaustive swimming models. Rats in each moxibustion group received mild moxibustion for 15 min immediately after the exhaustive modeling, once every other day. Twenty-four hours after the corresponding exhaustive exercise, the rats in each group were tested for the levels of serum immunoglobulin (Ig) G, IgA, IgM and acid phosphatase (ACP), and the morphological changes of spleen tissues were observed. The level of IgA was detected by immunoturbidimetric assay, and the levels of IgG, IgM and ACP were detected by en zyme-linked imm uno sorb ent assay (ELISA). Results: Compared with the 1-time exhaustive group, swimming time of rats in the 4-time exhaustive group was significantly proIonged (P<0.01), and swimming time of rats in the 7-time exhaustive group was significantly shortened (P<0.01). Compared with the 7-time exhaustive group, exhaustive swimming time of rats in the 7-time moxibustion group was significantly proIonged (P<0.01). Compared with the blank group, the IgG level in the 1-time exhaustive group was significantly decreased (PvO.Ol), and the levels of IgG, IgA and IgM in the 4-time exhaustive group and the 7-time exhaustive group were all sign ifica ntly decreased (P<0.05 or PvO.Ol), while the ACP level was in creased sign ifica ntly (both P<0.01). Microscopically, the number of splenic corpuscles in the 1-time exhaustive group was reduced;the center of some splenic corpuscles in the 4-time exhaustive group was damaged;the number of splenic corpuscles in the 7-time exhaustive group was reduced, and there was no obvious germinal center. Compared with the 4-time exhaustive group, the IgA level in the 4-time moxibusti on group was sign ifica ntly in creased (P<0.01), and the ACP level was sign ifica ntly decreased (P<0.01). Compared with the 7-time exhaustive group, the levels of IgG, IgA and IgM in the 7-time moxibustion group were sign ifica ntly in creased (all PvO.Ol), and the ACP level was sign ifica ntly decreased (P<0.01). Microscopically, the nu mber of splenic corpuscles in the 1-time moxibustion group was reduced;the center of some splenic corpuscles in the 4-time moxibustion group was damaged together with hyperplasia of some splenic corpuscles;blast cells were proliferated in the center of some splenic corpuscles in the 7-time moxibustion group. Conclusion: Moxibustion at Shenque (CV 8) can improve the levels of IgG, IgA and IgM, reduce the ACP level, repair damaged spleen tissues, and enhance the immunity of the body to some extent in the Iong-term fatigue rats.

Clinical Study on Moxibustion at Shenque(CV 8)for Chronic Urticaria

Objective:To observe the safety and efficacy of moxibustion at Shenque(CV 8)for chronic urticaria.Methods:A total of 80 cases who met the inclusion criteria were randomly allocated into a treatment group and a control group,40 in each.Cases in the treatment group were treated with thunder-fire moxibustion at Shenque(CV 8),whereas cases in the control group were treated with Mizolastine.Changes in clinical symptoms such as itching and skin lesion were observed before and after treatment and the therapeutic efficacies were assessed.Results:After treatment,the total scores of clinical symptoms in both groups were markedly reduced(P<0.05),and the reduction was more significant in the treatment group than that in the control group(P<0.05).The total effective rate in the treatment group was 77.5%,versus 65.0%in the control group,showing no significant difference(P>0.05).The Ridit analysis showed a between-group significant difference in therapeutic efficacy grades(P<0.05).There were no reports of adverse reactions in the treatment group and 2 cases experienced mild somnolence in the control group.Conclusion:With an exact effect for chronic urticaria,moxibustion at Shenque(CV 8)obtained better results in overall efficacy and improving symptoms than oral administration of Mizolastine.

Effect of moxibustion at Shenque(CV 8)on myocardial remodeling and function in exercise-induced fatigue rats

Objective To explore the effect of moxibustion at Shenque(CV 8)on myocardial structure and function in exercise-induced fatigue rats.Methods A 12-week treadmill running training was performed to create an exercise-induced fatigue rat model.Sixty eligible male specific-pathogen-free grade Sprague-Dawley rats were randomly divided into a blank group,a control group,a model group,a non-meridian non-acupoint group,a Zusanli(ST 36)group and a Shenque(CV 8)group,with 10 rats in each group.Rats in the blank group did not receive treadmill running training or moxibustion.Rats in the control group did not receive treadmill running training but received mild moxibustion at Shenque(CV 8).Rats in the model group received treadmill running training but no moxibustion.Rats in the non-meridian non-acupoint group,the Zusanli(ST 36)group and the Shenque(CV 8)group received moxibustion at the non-meridian non-acupoint points,Zusanli(ST 36)or Shenque(CV 8)immediately after each treadmill running training,15 min each time,once a day for 5 consecutive days a week at a 2-day interval,60 times of moxibustion in total.Left ventricular end-diastolic diameter(LVEDd),left ventricular end-systolic diameter(LVESd),left ventricular diastolic volume(LVDv),left ventricular systolic volume(LVSv),ejection fraction(EF),stroke volume(SV),early diastolic peak flow velocity of mitral valve(E)and late diastolic peak flow velocity of mitral valve(A)of each group before and after the last treadmill running training were measured.Blood was collected 6 h after the last treadmill running training,and serum C-reactive protein(CRP),myoglobin(Mb),creatine kinase-myocardial band(CK-MB),cardiac troponin I(cTnI)and cardiac troponin T(cTnT)levels were detected.Finally,the heart was separated,the heart mass(HM)was measured,the cTnT level of the myocardial tissue was detected,the ultrastructural changes of the left ventricular myocardium were observed by transmission electron microscope,the left ventricular fraction shortening(LVFS),E/A and heart mass index(HMI)were calculated.Results Compared with the same group before treatment,the rat cardiac LVEDd,LVESd,LVDv,LVSv,SV,E and A were significantly increased(all P<0.01),and the rat LVFS,E/A and EF were significantly decreased(all P<0.01)in the model group and the non-meridian non-acupoint group after treatment;the rat cardiac SV,LVDv,LVSv,E and A were all increased(all P<0.01),while E/A and EF were decreased(all P<0.01)in the Zusanli(ST 36)group after treatment;the rat cardiac LVDv,E and A were significantly increased(P<0.01 or P<0.05),and E/A was significantly decreased(P<0.01)in the Shenque(CV 8)group after treatment.After treatment,compared with the blank group,the rat cardiac LVEDd,LVESd,SV,LVDv,LVSv,E,A,the serum CRP,Mb,CK-MB,cTnI,cTnT and HMI,and the myocardial cTnT were increased(all P<0.01),and the LVFS,E/A and EF were all reduced(all P<0.01)in the model group;compared with the model group and the non-meridian non-acupoint group,rats in the Zusanli(ST 36)group and the Shenque(CV 8)group showed decreased LVEDd,LVESd,SV,LVDv,LVSv,E,A,serum CRP,Mb,CK-MB,cTnI,cTnT and HMI,and myocardial cTnT(P<0.01 or P<0.05),along with increased LVFS,E/A and EF(all P<0.01);compared with the Zusanli(ST 36)group,Mb and A of the Shenque(CV 8)group were decreased(both P<0.01),while both E/A and EF were increased(P<0.01,P<0.05).Transmission electron microscopy examination showed that myofibrils in the blank group and the control group were neatly arranged with clear light and dark bands;the model group and the non-meridian non-acupoint group showed different degrees of myofibril disintegration and breakage,increased and aggregated mitochondria of different sizes,and increased electron density.The myofibrils in the Shenque(CV 8)group and Zusanli(ST 36)group were arranged neatly with clear light and dark bands,and compensatory hyperplasia of mitochondria.Conclusion Moxibustion at Shenque(CV 8)and Zusanli(ST 36)both can effectively improve the occurrence of myocardial remodeling in exercise-induced fatigue rats,and the effect of moxibustion at Shenque(CV 8)is better in improving cardiac function.

Clinical observation of Da Huang (Rheum Officinale) application at Shenque(CV 8) for constipation after operation for lumbar vertebral fracture

Objective： To observe the effect of Da Huang（Rheum Officinale） application at Shenque（CV 8） on constipation after operation for lumbar vertebral fracture.Methods： Seventy-four patients with constipation after operation for lumbar vertebral fracture were divided into an observation group and a control group by the random number table, 37 cases in each group. The two groups both received ordinary treatment（including healthcare guidance, emotional care, diet arrangement, and defecation nursing）, while the observation group was additionally given Da Huang（Rheum Officinale） application at Shenque（CV 8） for 6 h each day. The therapeutic efficacy was evaluated after successive 3-day treatment. Results： After 3-day treatment, it took significantly less time for the observation group to conduct the first flatulence and defecation than for the control group（P〈0.05）; the therapeutic efficacy of the observation group was significantly higher than that of the control group（P〈0.01）. Conclusion： Da Huang（Rheum Officinale） application at Shenque（CV 8） is effective in treating constipation after lumbar vertebral fracture operation, and it＇s easy-to-operate and well accepted by patients, hence it＇s proper to promote this method in clinic.

隔物灸对寒湿凝滞型原发性痛经患者经期血浆β-EP含量的影响

目的:探讨隔物灸治疗寒湿凝滞型原发性痛经的作用机制。方法:以隔物灸治疗寒湿凝滞型原发性痛经患者105例(隔物灸组),并设中药月月舒作对照104例(药物组),观察临床疗效,同时对两组各40例进行了治疗前后经期β-内啡肽(β-EP)含量的变化检测。结果:隔物灸组总有效率为95.2%,优于药物组的85.6%(P<0.05);隔物灸组β-EP水平较治疗前明显升高(P<0.01)。结论:隔物灸对寒湿凝滞型原发性痛经患者有明显的治疗作用,其作用机制之一可能是通过调节血浆中β-EP的水平而发挥止痛效应。

神阙隔药灸疗法治疗溃疡性结肠炎的临床观察

目的观察神阙隔药灸疗法治疗溃疡性结肠炎(UC)的疗效及对自身免疫水平的影响,并探讨其作用机制。方法将60例UC患者随机分为治疗组(30例)和对照组(30例)。治疗组采用神阙隔药灸疗法,对照组口服柳氮磺胺吡啶片和甲硝唑片,比较两组治疗前后主要症状及肠黏膜病变变化和总疗效,观察血清免疫球蛋白、外周血T细胞亚群与自然杀伤细胞(NK)含量变化。结果治疗组显效率、总有效率分别为60·0%、86·7%,明显优于对照组的23·3%、66·7%,两组间比较差异有显著性或非常显著性意义(P<0·05,P<0·01)。治疗组治疗后IgG显著降低,与对照组治疗后比较差异有显著性意义(P<0·05);治疗前后IgA、IgM无明显变化(P>0·05)。治疗组治疗后外周血T细胞亚群与NK细胞含量均不同程度增高,增高幅度与疗效呈正相关。结论神阙隔药灸疗法是治疗溃疡性结肠炎的满意方法,其作用机制可能通过调节机体的免疫功能发挥疗效。

隔药灸脐法治疗原发性痛经临床研究

目的观察隔药灸脐与针刺三阴交穴对原发性痛经患者症状的影响,比较其疗效差异。方法将60例原发性痛经患者随机分为灸脐组和针刺组,每组30例。观察治疗3个月经周期后COX痛经症状评分量表(the Cox Menstrual Symptom Scale)的变化,并比较两组之间的差异。结果灸脐组与针刺组治疗前后COX痛经症状评分比较差异均有统计学意义(P<0.05),且灸脐组疗效优于针刺组(P<0.05)。结论隔药灸脐法治疗原发性痛经疗效较好。

电热隔药贴灸对老年前期大鼠大脑皮质单胺类神经递质含量的影响

目的 :探讨“神阙”延缓衰老的作用机理。方法 :取 18～ 2 0月龄老年前期SD大鼠随机分组治疗 ,采用荧光比色法测定单胺类神经递质。结果 :电热隔药贴灸“神阙”穴能显著提高老年前期大鼠大脑皮质单胺类神经递质的含量 ,与老年前期空白组比较差异具有显著性意义 ,与传统隔药灸组比较差异无显著性意义。结论 :电热隔药灸“神阙”穴能够对老年前期大鼠大脑皮质单胺类神经递质含量的增龄性改变产生良性影响 ,并与传统隔药灸法的作用相似。

隔药灸脐法治疗脾虚型肠易激综合征临床研究

目的比较隔药灸脐法与隔淀粉灸脐法治疗脾虚型肠易激综合征的疗效差异。方法选取40例脾虚泄泻型肠易激综合征患者,随机分成两组,每组20例,观察组采用隔药灸,对照组采用隔淀粉灸,对两组疗效进行比较。结果两组脾虚泄泻症状评分在治疗期和随访期与治疗前比较均有统计学差异(P<0.01),且隔药灸脐较隔淀粉灸脐可以更好地改善患者泄泻症状。结论脐疗可以有效地改善泄泻症状,隔药灸脐优于隔淀粉灸脐。

隔药灸治疗寒凝型痛经的疗效及对PGF_(2α)、PGE_2影响

目的探讨隔药灸治疗寒凝型痛经的作用机制。方法把60例寒凝型痛经患者按随机数字表分为两组,每组30例,隔药灸组采用隔药灸神阙穴,西药组采用内服西药,并设正常空白组30例不作任何治疗。结果隔药灸组总有效率(96.7%)优于西药组(83.3%)(P<0.05)。隔药灸组治疗后PGF2α、PGE2与西药组比较差异有统计学意义(P<0.01)。结论隔药灸治疗寒凝型痛经的疗效机制与调节PGF2α及PGE2有关,即可降低经期外周血PGF2α含量,升高PGE2含量。

“神阙”穴隔药灸对荷瘤化疗大鼠胃粘膜保护作用的研究

以荷Ｗ２５６大鼠为观察对象，观察“神阙”穴隔药灸抗肿瘤化疗药物氟尿嘧啶（５Ｆｕ）消化道毒性反应的疗效。结果显示：“神阙”穴隔药灸能促使胃粘膜ＰＧＥ２水平、胃粘膜血流量明显升高，使胃粘膜损伤指数降低，胃粘膜厚度较化疗组略有增厚。表明“神阙”穴隔药灸对化疗药物（５Ｆｕ）所致胃粘膜损伤有保护作用，此与其提高胃粘膜ＰＧＥ２水平、改善胃粘膜血流量有关。

针刺加神阙隔盐灸治疗黄褐斑60例疗效观察

目的 :观察针刺加神阙隔盐灸治疗黄褐斑的临床疗效。方法 :将 10 6例黄褐斑患者随机分为两组 ,治疗组 6 0例采用针刺加神阙隔盐灸治疗 ,对照组 4 6例采用单纯针刺治疗。两组均治疗 3个疗程并随访 1个月观察疗效。结果 :治疗组总有效率为 10 0 0 % ,对照组为 89 1% ,二者疗效差异有显著性意义 (P <0 0 5 )。结论 :针刺加神阙隔盐灸对黄褐斑是一种安全有效的治疗方法。

神阙灸配合电针治疗阳虚寒凝型膝骨关节炎疗效观察

目的:评价神阙灸配合电针局部穴位治疗阳虚寒凝型膝骨关节炎(Osteoarthritis,OA)的作用。方法:采用单盲、随机对照的设计方法,将60例(104膝)患者随机分为2组,观察组30例(54膝),采用神阙灸配合电针局部针刺犊鼻、内膝眼、阳陵泉、阿是穴等;对照组30例(50膝),用神阙安慰灸配合电针局部治疗,穴位同观察组。2组均每日治疗1次,10次为一疗程,经1个疗程治疗后,比较疗效结果,1个月后随访,再次评价疗效。结果:观察组治疗后疼痛疗效结果为临床治愈42膝、显效11膝、有效1膝,综合疗效结果为优37膝、良16膝、可1膝;对照组治疗后疼痛疗效结果为临床治愈13膝、显效35膝、有效2膝,综合疗效结果为优9膝、良40膝、可1膝,2组结果经秩和检验,均P<0.01,差异均有非常显著性意义,观察组优于对照组。1个月后随访时2组间疼痛疗效和综合疗效结果经秩和检验,其中疼痛疗效P>0.05,综合疗效比较,P<0.01。结论:神阙灸配合电针局部穴位治疗阳虚寒凝型膝OA具有较好的临床疗效,优于神阙安慰灸配合电针局部穴位者。

艾灸联合神阙穴贴敷改善肝硬化腹水

目的探讨艾灸联合神阙穴贴敷对肝硬化腹水的改善效果。方法根据入院先后顺序,将90例肝硬化腹水患者均分为3组,分别予艾灸组(A组)、神阙穴贴敷组(B组)以及艾灸联合神阙穴贴敷组(C组)干预。28 d后比较3组24 h尿量、腹围、体质量等指标以评价效果。结果干预后,3组在体质量、腹围、尿量等方面均有所改善(P<0.01);组间比较发现,A组和B组之间差异无统计学意义(P>0.05),而C组在体质量、腹围、尿量方面均优于A、B组(均P<0.05)。C组症状改善有效率(96.7%)高于A、B组,(P<0.05)。结论艾灸联合神阙穴贴敷能够改善肝硬化腹水,减轻症状。

隔药灸脐法延缓衰老临床观察

目的:观察隔药灸脐疗法延缓衰老的临床疗效及作用机制。方法:将71例患者随机分为3组,其中隔药灸脐组30例,采用隔药灸脐治疗,每周2次;针刺组21例,取肾俞、太溪为主穴,每日1次;西药组20例,口服VitE胶囊,每次0.1g,每日2次。比较3组的临床疗效,以及治疗前后症状积分、血清超氧化物歧化酶(SOD)、血清丙二醛(MDA)含量变化。结果:治疗后3组临床症状均有非常显著的改善(P<0.01),且隔药灸脐组改善更显著(P<0.01);3组SOD含量均明显提高(P<0.01),MDA含量均明显降低(P<0.01),隔药灸脐组与针刺组相比SOD、MDA含量差异均无显著性意义(P>0.05),隔药灸脐组与西药组相比SOD、MDA含量差异均有显著性意义(P<0.05)。结论:隔药灸脐法能明显延缓衰老,其机制与改善体内SOD、MDA含量有关。