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基于King达标理论的培训方案对临床护士叙事能力及人文关怀能力的影响
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作者 季晓红 郭琳瑶 +3 位作者 房晓杰 胡林 魏玉莲 乔娟 《循证护理》 2024年第15期2846-2850,共5页
目的:探讨基于King达标理论构建临床护士叙事护理培训方案对临床护士叙事护理能力、人文关怀能力及共情能力的影响。方法:2023年3月—5月选取淄博市某三级甲等医院138名护士,采用随机数字表法分为试验组和对照组。对照组实施常规叙事护... 目的:探讨基于King达标理论构建临床护士叙事护理培训方案对临床护士叙事护理能力、人文关怀能力及共情能力的影响。方法:2023年3月—5月选取淄博市某三级甲等医院138名护士,采用随机数字表法分为试验组和对照组。对照组实施常规叙事护理培训,试验组在对照组的基础上实施基于King达标理论指导下的叙事护理方案。采用医学叙事能力量表(NCS)、关怀能力评价量表(CAI)、杰弗逊共情量表(JSE-HP)进行效果评价。结果:干预后,试验组护士NCS、CAI及JSE-HP得分均高于对照组,差异均有统计学意义(P<0.05)。结论:基于King达标理论构建的临床护士叙事培训方案可有效提高临床护士叙事护理能力、促进人文关怀能力并提升护士共情能力。 展开更多
关键词 叙事护理 人文关怀 共情 king达标理论 护理
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Comprehensive effects of traditional Chinese medicine treatment on heart failure and changes in B-type natriuretic peptide levels: A meta-analysis
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作者 Li-Li Xia Shu-Yun Yang +2 位作者 Jun-Yao Xu Han-Qing Chen Zhu-Yuan Fang 《World Journal of Clinical Cases》 SCIE 2024年第4期766-776,共11页
BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,... BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious. 展开更多
关键词 Traditional Chinese medicine Heart failure Comprehensive clinical outcomes Traditional Chinese medicine syndrome score B-type natriuretic peptide level Meta-analysis©The Author(s)2024.Published by Baishideng Publishing Group Inc.
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臂丛颈丛神经阻滞麻醉联合瑞芬太尼在锁骨骨折中的应用及对OAA/S评分、VAS评分的影响
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作者 罗晶 刘轶 熊艳 《吉林医学》 CAS 2024年第5期1133-1136,共4页
目的:观察臂丛颈丛神经阻滞麻醉联合瑞芬太尼用于锁骨骨折手术的效果。方法:选取吉安市永丰县中医院2019年1月~2022年11月就诊的锁骨骨折患者140例为研究对象,按照收治的先后顺序随机分为试验组和对照组各70例,对照组予以臂丛颈丛神经... 目的:观察臂丛颈丛神经阻滞麻醉联合瑞芬太尼用于锁骨骨折手术的效果。方法:选取吉安市永丰县中医院2019年1月~2022年11月就诊的锁骨骨折患者140例为研究对象,按照收治的先后顺序随机分为试验组和对照组各70例,对照组予以臂丛颈丛神经阻滞麻醉,试验组在对照组基础上加用瑞芬太尼。记录两组麻醉前(T0)、臂丛颈丛神经阻滞麻醉后15 min(T1)、辅助用药后3 min(T2)、手术开始后5 min(T3)、手术开始后15 min(T4)、手术结束时(T5)的平均动脉压(MAP)、心率(HR)、脉搏血氧饱和度(SpO 2)。同时观察两组期间的不良反应以及血管活性药麻黄碱、阿托品、尼卡地平以及艾司洛尔的例数。比较两组患者麻醉满意度的差异。结果:对照组T2时血压降低、心率减慢均不明显,与T0比较差异无统计学意义(P>0.05)。试验组T3、T4时血压升高、心率增快明显,与T0和对照组比较差异有统计学意义(P<0.05)。试验组T2血压降低、心率减慢明显,与对照组和T0比较差异有统计学意义(P>0.05),随后趋于平稳。试验组血管活性药物尼卡地平以及艾司洛尔的例数少于对照组,差异有统计学意义(P<0.05)。两组视觉模拟评分(VAS)及镇痛效果满意率比较差异有统计学意义(P<0.05)。结论:臂丛颈丛神经阻滞麻醉联合瑞芬太尼用于锁骨骨折切开复位内固定手术,镇静镇痛效果确切,呼吸循环稳定,患者麻醉满意度高,是一种安全、有效的麻醉方法。 展开更多
关键词 臂丛颈丛神经阻滞 瑞芬太尼 锁骨骨折 OAA/s评分 VAs评分
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血清S-100β、BUN联合APACHE Ⅱ评分评估老年脓毒症患者预后的价值
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作者 胡海强 谢勇 江怡 《现代临床医学》 2024年第4期284-286,290,共4页
目的:探讨血清中枢神经特异性蛋白β(S-100β)、血尿素氮(BUN)联合急性生理学及慢性健康状况评分系统Ⅱ(APACHEⅡ)评分评估老年脓毒症患者预后的价值。方法:选取2022年4月至2023年6月新余北湖医院收治的102例老年脓毒症患者,根据APACHE... 目的:探讨血清中枢神经特异性蛋白β(S-100β)、血尿素氮(BUN)联合急性生理学及慢性健康状况评分系统Ⅱ(APACHEⅡ)评分评估老年脓毒症患者预后的价值。方法:选取2022年4月至2023年6月新余北湖医院收治的102例老年脓毒症患者,根据APACHE Ⅱ评分将其分为轻、中、重3组,按改良Rankin量表将患者分为预后良好组与预后不良组,比较各组S-100β、BUN、APACHE Ⅱ评分的差异,并分析S-100β、BUN与APACHE Ⅱ评分的相关性,以及三者评估老年脓毒症患者预后的价值。结果:重度组的S-100β、BUN、APACHE Ⅱ评分高于中、轻度组,预后不良组的S-100β、BUN、APACHE Ⅱ评分高于预后良好组(P<0.05);S-100β、BUN与APACHE Ⅱ评分呈正相关(r=0.458、0.479,P<0.05);ROC曲线分析显示,S-100β、BUN联合APACHEⅡ评分评估老年脓毒症患者预后的曲线下面积为0.928,高于三者单独评估。结论:S-100β、BUN联合APACHEⅡ评分对老年脓毒症患者预后有较高的评估价值。 展开更多
关键词 老年脓毒症 s-100Β BUN APACHEⅡ评分 预后
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Altman’s Z-Score模型在企业风险管理中的应用研究 被引量:23
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作者 徐秀渠 《经济经纬》 CSSCI 北大核心 2010年第4期103-106,共4页
随着市场竞争的加剧,信息化、高科技化进程的加快,企业决策难度、经营成本和收益的波动增大,企业风险管理彰显出重要性。笔者通过对沪、深证券交易所2007年~2009年暂停上市或终止上市的32家公司的Z值分析,认为用Altman’s Z-Score模型... 随着市场竞争的加剧,信息化、高科技化进程的加快,企业决策难度、经营成本和收益的波动增大,企业风险管理彰显出重要性。笔者通过对沪、深证券交易所2007年~2009年暂停上市或终止上市的32家公司的Z值分析,认为用Altman’s Z-Score模型预测企业风险是有效的。根据对Altman’s Z-Score模型组成变量的比较分析,笔者提出了企业防范风险的有关措施。 展开更多
关键词 Altman's Z-score模型 暂停上市 终止上市 风险管理
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An Analysis of Interpersonal Function of the Dialogues in the Film The King's Speech
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作者 杨越森 《海外英语》 2015年第6期236-240,252,共6页
Based on the framework of Halliday's theory of interpersonal function, this study intends to analyze the dialogues in the film The King's Speech from the three aspects of mood type, modal operator and vocative... Based on the framework of Halliday's theory of interpersonal function, this study intends to analyze the dialogues in the film The King's Speech from the three aspects of mood type, modal operator and vocative address by adopting both quantitative and qualitative methods. The significances of successful realizations of interpersonal function to the role characterization, plot development and thematic construction in the film are also demonstrated, thus deepening the understanding and appreciation of the film. 展开更多
关键词 INTERPERsONAL function The king’s sPEECH MOOD type MODAL operator vocative ADDREss
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Sequential organ failure assessment score is superior to other prognostic indices in acute pancreatitis 被引量:12
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作者 Thomas Zheng Jie Teng Jun Kiat Thaddaeus Tan +5 位作者 Samantha Baey Sivaraj K Gunasekaran Sameer P Junnarkar Jee Keem Low Cheong Wei Terence Huey Vishal G Shelat 《World Journal of Critical Care Medicine》 2021年第6期355-368,共14页
BACKGROUND Acute pancreatitis(AP)is a common surgical condition,with severe AP(SAP)potentially lethal.Many prognostic indices,including;acute physiology and chronic health evaluation II score(APACHE II),bedside index ... BACKGROUND Acute pancreatitis(AP)is a common surgical condition,with severe AP(SAP)potentially lethal.Many prognostic indices,including;acute physiology and chronic health evaluation II score(APACHE II),bedside index of severity in acute pancreatitis(BISAP),Glasgow score,harmless acute pancreatitis score(HAPS),Ranson’s score,and sequential organ failure assessment(SOFA)evaluate AP severity and predict mortality.AIM To evaluate these indices'utility in predicting severity,intensive care unit(ICU)admission,and mortality.METHODS A retrospective analysis of 653 patients with AP from July 2009 to September 2016 was performed.The demographic,clinical profile,and patient outcomes were collected.SAP was defined as per the revised Atlanta classification.Values for APACHE II score,BISAP,HAPS,and SOFA within 24 h of admission were retrospectively obtained based on laboratory results and patient evaluation recorded on a secure hospital-based online electronic platform.Data with<10%missing data was imputed via mean substitution.Other patient information such as demographics,disease etiology,and patient outcomes were also derived from electronic medical records.RESULTS The mean age was 58.7±17.5 years,with 58.7%males.Gallstones(n=404,61.9%),alcohol(n=38,5.8%),and hypertriglyceridemia(n=19,2.9%)were more common aetiologies.81(12.4%)patients developed SAP,20(3.1%)required ICU admission,and 12(1.8%)deaths were attributed to SAP.Ranson’s score and APACHE-II demonstrated the highest sensitivity in predicting SAP(92.6%,80.2%respectively),ICU admission(100%),and mortality(100%).While SOFA and BISAP demonstrated lowest sensitivity in predicting SAP(13.6%,24.7%respectively),ICU admission(40.0%,25.0%respectively)and mortality(50.0%,25.5%respectively).However,SOFA demonstrated the highest specificity in predicting SAP(99.7%),ICU admission(99.2%),and mortality(98.9%).SOFA demonstrated the highest positive predictive value,positive likelihood ratio,diagnostic odds ratio,and overall accuracy in predicting SAP,ICU admission,and mortality.SOFA and Ranson’s score demonstrated the highest area under receiver-operator curves at 48 h in predicting SAP(0.966,0.857 respectively),ICU admission(0.943,0.946 respectively),and mortality(0.968,0.917 respectively).CONCLUSION The SOFA and 48-h Ranson’s scores accurately predict severity,ICU admission,and mortality in AP,with more favorable statistics for the SOFA score. 展开更多
关键词 PANCREATITIs severity scoring Intensive care unit Mortality sequential Organ Failure Assessment score Ranson’s score
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基于King达标理论的心理干预结合亲情干预模式对BPH患者行PKEP术后恢复情况及GQOLI-74、IPSS评分的影响 被引量:77
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作者 蒋文华 施晓萍 +2 位作者 黄静 李洁鸣 郭晓 《中国医药导报》 CAS 2020年第5期164-168,共5页
目的研究基于King达标理论的心理干预结合亲情干预模式对前列腺增生(BPH)患者行经尿道双极等离子前列腺剜除术(PKEP)术后恢复情况及生活质量综合评定问卷(GQOLI-74)、国际前列腺症状评分(IPSS)的影响。方法选择2017年8月~2019年2月浙江... 目的研究基于King达标理论的心理干预结合亲情干预模式对前列腺增生(BPH)患者行经尿道双极等离子前列腺剜除术(PKEP)术后恢复情况及生活质量综合评定问卷(GQOLI-74)、国际前列腺症状评分(IPSS)的影响。方法选择2017年8月~2019年2月浙江省嘉兴市第二医院收治的BPH患者120例作为研究对象,采用随机数字表法将其分为对照组和观察组,每组60例.两组患者均采取PKEP治疗,手术治疗后,对照组患者采取常规护理措施,观察组患者采取基于King达标理论的心理干预结合亲情干预模式,两组患者的护理时间均为4周。比较两组患者的围术期指标、症状改善情况、并发症、生命质量以及依从性之间的差异。结果两组IPSS评分、最大尿流速(Qmax)、残余尿量(RUV)组内治疗前后比较,差异均有统计学意义(均P<0.05),治疗后两组手术时间、术中出血量、切除组织量、IPSS评分、Qmax、RUV之间比较,差异均无统计学意义(P>0.05);治疗后,两组患者的生命质量评分均升高,且观察组患者的生命质量评分均显著高于对照组,差异有统计学意义(P<0.05),两组患者的遵医嘱服药行为以及不良服药行为、日常生活管理行为、烟酒嗜好管理行为、依从性总分均高于治疗前,且观察组各项评分均高于对照组,差异均有统计学意义(P<0.05)。结论通过对BPH患者基于King达标理论的心理干预结合亲情干预模式护理,患者GQOLI-74、IPSS评分显著改善,患者的并发症显著下降,对患者的治疗具有积极的意义。 展开更多
关键词 前列腺增生 依从性 生命质量 king达标理论的心理干预 亲情护理干预
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Short-term efficacy of robotic and laparoscopic spleen-preserving splenic hilar lymphadenectomy via Huang’s three-step maneuver for advanced upper gastric cancer: Results from a propensity scorematched study 被引量:2
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作者 Jia-Bin Wang Zhi-Yu Liu +14 位作者 Qi-Yue Chen Qing Zhong Jian-Wei Xie Jian-Xian Lin Jun Lu Long-Long Cao Mi Lin Ru-Hong Tu Ze-Ning Huang Ju-Li Lin Hua-Long Zheng Si-Jin Que Chao-Hui Zheng Chang-Ming Huang Ping Li 《World Journal of Gastroenterology》 SCIE CAS 2019年第37期5641-5654,共14页
BACKGROUND Robotic surgery has been considered to be significantly better than laparoscopic surgery for complicated procedures.AIM To explore the short-term effect of robotic and laparoscopic spleen-preserving splenic... BACKGROUND Robotic surgery has been considered to be significantly better than laparoscopic surgery for complicated procedures.AIM To explore the short-term effect of robotic and laparoscopic spleen-preserving splenic hilar lymphadenectomy(SPSHL)for advanced gastric cancer(GC)by Huang’s three-step maneuver.METHODS A total of 643 patients who underwent SPSHL were recruited from April 2012 to July 2017,including 35 patients who underwent robotic SPSHL(RSPSHL)and 608 who underwent laparoscopic SPSHL(LSPSHL).One-to-four propensity score matching was used to analyze the differences in clinical data between patients who underwent robotic SPSHL and those who underwent laparoscopic SPSHL.RESULTS In all,175 patients were matched,including 35 patients who underwent RSPSHL and 140 who underwent LSPSHL.After matching,there were no significant differences detected in the baseline characteristics between the two groups.Significant differences in total operative time,estimated blood loss(EBL),splenic hilar blood loss(SHBL),splenic hilar dissection time(SHDT),and splenic trunk dissection time were evident between these groups(P<0.05).Furthermore,no significant differences were observed between the two groups in the overall noncompliance rate of lymph node(LN)dissection(62.9%vs 60%,P=0.757),number of retrieved No.10 LNs(3.1±1.4 vs 3.3±2.5,P=0.650),total number of examined LNs(37.8±13.1 vs 40.6±13.6,P=0.274),and postoperative complications(14.3%vs 17.9%,P=0.616).A stratified analysis that divided the patients receiving RSPSHL into an early group(EG)and a late group(LG)revealed that the LG experienced obvious improvements in SHDT and length of stay compared with the EG(P<0.05).Logistic regression showed that robotic surgery was a significantly protective factor against both SHBL and SHDT(P<0.05).CONCLUSION RSPSHL is safe and feasible,especially after overcoming the early learning curve,as this procedure results in a radical curative effect equivalent to that of LSPSHL. 展开更多
关键词 Advanced gastric cancer ROBOTIC surgery LAPAROsCOPIC surgery Dissection of sPLENIC HILAR lymph node Propensity score matching Huang’s three-step MANEUVER
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Short-term and long-term outcomes of laparoscopic vs open ileocolic resection in patients with Crohn's disease: Propensityscore matching analysis 被引量:1
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作者 Shin Jeong Pak Young Il Kim +3 位作者 Yong Sik Yoon Jong Lyul Lee Jung Bok Lee Chang Sik Yu 《World Journal of Gastroenterology》 SCIE CAS 2021年第41期7159-7172,共14页
BACKGROUND Laparoscopic ileocolic resection(LICR)is the preferred surgical approach for primary ileocolic Crohn’s disease(CD)because it has greater recovery benefits than open ICR(OICR).AIM To compare short-and long-... BACKGROUND Laparoscopic ileocolic resection(LICR)is the preferred surgical approach for primary ileocolic Crohn’s disease(CD)because it has greater recovery benefits than open ICR(OICR).AIM To compare short-and long-term outcomes in patients who underwent LICR and OICR.METHODS Patients who underwent ICR for primary CD from 2006 to 2017 at a single tertiary center specializing in CD were included.Patients who underwent LICR and OICR were subjected to propensity-score matching analysis.Patients were propensityscore matched 1:1 by factors potentially associated with 30-d perioperative morbidity.These included demographic characteristics and disease-and treatment-related variables.Factors were compared using univariate and multivariate analyses.Long-term surgical recurrence-free survival(SRFS)in the two groups was determined by the Kaplan-Meier method and compared by the log-rank test.RESULTS During the study period,348 patients underwent ICR,211 by the open approach and 137 laparoscopically.Propensity-score matching yielded 102 pairs of patients.The rate of postoperative complication was significantly lower(14%versus 32%,P=0.003),postoperative hospital stay significantly shorter(8 d versus 13 d,P=0.003),and postoperative pain on day 7 significantly lower(1.4 versus 2.3,P<0.001)in propensity-score matched patients who underwent LICR than in those who underwent OICR.Multivariate analysis showed that postoperative complications were significantly associated with preoperative treatment with biologics[odds ratio(OR):3.14,P=0.01]and an open approach to surgery(OR:2.86,P=0.005).The 5-and 10-year SRFS rates in the matched pairs were 92.9%and 83.3%,respectively,with SRFS rates not differing significantly between the OICR and LICR groups.The performance of additional procedures was an independent risk factor for surgical recurrence[hazard ratio(HR):3.28,P=0.02].CONCLUSION LICR yielded better short-term outcomes and postoperative recovery than OICR,with no differences in long-term outcomes.LICR may provide greater benefits in selected patients with primary CD. 展开更多
关键词 Crohn’s disease LAPAROsCOPIC sURGERY Postoperative complications RECURRENCE Propensity score Retrospective study
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Ishii评分在养老机构老年人肌少症筛查中的应用 被引量:3
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作者 黄姣玲 华楠 +2 位作者 姚雪梅 李玉华 王秀华 《护理学杂志》 CSCD 北大核心 2023年第4期100-103,共4页
目的评价Ishii评分在养老机构老年人肌少症筛查中的准确性,为养老机构老年人肌少症筛查提供适用性工具。方法对养老机构386名老年人应用Ishii评分进行肌少症筛查,以亚洲肌少症工作组推荐的肌少症诊断标准为参考,使用灵敏度、特异度及RO... 目的评价Ishii评分在养老机构老年人肌少症筛查中的准确性,为养老机构老年人肌少症筛查提供适用性工具。方法对养老机构386名老年人应用Ishii评分进行肌少症筛查,以亚洲肌少症工作组推荐的肌少症诊断标准为参考,使用灵敏度、特异度及ROC曲线下面积等指标评价Ishii评分肌少症筛查效应。结果肌少症检出率为49.7%,其中男91人,女101人;男性Ishii评分ROC曲线下面积为0.844,95%CI为0.786~0.902,女性Ishii评分ROC曲线下面积为0.806,95%CI为0.748~0.863;男性和女性分别在以137和161分为截断值时,约登指数达到最高水平。结论Ishii评分对于养老机构老年人肌少症筛查具有较高的筛检价值。 展开更多
关键词 老年人 肌少症 养老机构 Ishii评分 筛查工具 灵敏度 特异度
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Multi-locus genetic risk score predicts risk for Crohn's disease in Slovenian population
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作者 Katarina Zupancic Kristijan Skok +3 位作者 Katja Repnik Rinse K Weersma Uros Potocnik Pavel Skok 《World Journal of Gastroenterology》 SCIE CAS 2016年第14期3777-3784,共8页
AIM: To develop a risk model for Crohn's disease(CD) based on homogeneous population.METHODS: In our study were included 160 CD patients and 209 healthy individuals from Slovenia. The association study was perform... AIM: To develop a risk model for Crohn's disease(CD) based on homogeneous population.METHODS: In our study were included 160 CD patients and 209 healthy individuals from Slovenia. The association study was performed for 112 single nucleotide polymorphisms(SNPs). We generated genetic risk scores(GRS) based on the number of risk alleles using weighted additive model. Discriminatory accuracy was measured by area under ROC curve(AUC). For risk evaluation, we divided individuals according to positive and negative likelihood ratios(LR) of a test, with LR > 5 for high risk group and LR < 0.20 for low risk group.RESULTS: The highest accuracy, AUC of 0.78 was achieved with GRS combining 33 SNPs with optimal sensitivity and specificity of 75.0% and 72.7%, respectively. Individuals with the highest risk(GRS >5.54) showed significantly increased odds of developing CD(OR = 26.65, 95%CI: 11.25-63.15) compared to the individuals with the lowest risk(GRS < 4.57) which is a considerably greater risk captured than in one SNP with the highest effect size(OR = 3.24). When more than 33 SNPs were included in GRS, discriminatory ability was not improved significantly; AUC of all 74 SNPs was 0.76.CONCLUSION: The authors proved the possibility of building accurate genetic risk score based on 33 risk variants on Slovenian CD patients which may serve as a screening tool in the targeted population. 展开更多
关键词 Inflammatory BOWEL DIsEAsE Crohn’s DIsEAsE discriminatory accuracy Genetic RIsK score single nucleot
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Histopathological assessment of the microscopic activity in inflammatory bowel diseases:What are we looking for?
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作者 Ondrej Fabian Lukas Bajer 《World Journal of Gastroenterology》 SCIE CAS 2022年第36期5300-5312,共13页
Advances in diagnostics of inflammatory bowel diseases(IBD)and improved treatment strategies allowed the establishment of new therapeutic endpoints.Currently,it is desirable not only to cease clinical symptoms,but mai... Advances in diagnostics of inflammatory bowel diseases(IBD)and improved treatment strategies allowed the establishment of new therapeutic endpoints.Currently,it is desirable not only to cease clinical symptoms,but mainly to achieve endoscopic remission,a macroscopic normalization of the bowel mucosa.However,up to one-third of IBD patients in remission exhibit persisting microscopic activity of the disease.The evidence suggests a better predictive value of histology for the development of clinical complications such as clinical relapse,surgical intervention,need for therapy escalation,or development of colorectal cancer.The proper assessment of microscopic inflammatory activity thus became an important part of the overall histopathological evaluation of colonic biopsies and many histopathological scoring indices have been established.Nonetheless,a majority of them have not been validated and no scoring index became a part of the routine bioptic practice.This review summarizes a predictive value of microscopic disease activity assessment for the subsequent clinical course of IBD,describes the most commonly used scoring indices for Crohn's disease and ulcerative colitis,and comments on current limitations and unresolved issues. 展开更多
关键词 Crohn’s disease Microscopy PREDICTOR score Ulcerative colitis
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改良aEEG评分联合S-100β和GFAP对儿童癫痫性脑病早期诊断价值的分析
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作者 王君 罗琼 张美 《中国妇幼健康研究》 2023年第5期25-29,共5页
目的 探讨改良振幅整合脑电图(aEEG)评分联合中枢神经特异蛋白S100β(S-100β)和神经胶质纤维酸性蛋白(GFAP)对儿童癫痫性脑病早期诊断的价值。方法 选择2018年1月至2020年12月在新疆医科大学第一附属医院小儿神经内科就诊的癫痫持续状... 目的 探讨改良振幅整合脑电图(aEEG)评分联合中枢神经特异蛋白S100β(S-100β)和神经胶质纤维酸性蛋白(GFAP)对儿童癫痫性脑病早期诊断的价值。方法 选择2018年1月至2020年12月在新疆医科大学第一附属医院小儿神经内科就诊的癫痫持续状态患儿92例为研究对象。收集患儿的临床资料,在入院1~3d内行aEEG检查,入院24h内抽取空腹外周静脉血2mL检测S-100β和GFAP水平。根据有无癫痫性脑病将患儿分为癫痫性脑病组(34例)与非癫痫性脑病组(58例),比较两组的改良aEEG评分及S-100β、GFAP水平,并采用受试者工作特征(ROC)曲线评估各指标单独检测与联合检测对癫痫持续状态患儿癫痫性脑病的早期诊断价值。结果 在92例癫痫持续状态患儿中,有34例诊断为癫痫性脑病。癫痫性脑病组患儿的改良aEEG评分显著高于非癫痫性脑病组,S-100β和GFAP水平也显著高于非癫痫性脑病组,差异均有统计学意义(t值分别为3.411、7.261、6.579,P<0.05)。ROC曲线分析显示,改良aEEG评分及S-100β、GFAP水平对癫痫持续状态患儿癫痫性脑病早期诊断的截断值分别为8.10分、1.16μg/L、4.61ng/L,曲线下面积(AUC)分别为0.751、0.876、0.809,三者联合诊断的AUC为0.908,联合诊断效能均高于单独指标的检测(Z值分别为4.821、5.013、3.961,P<0.05)。结论 儿童癫痫性脑病可引起改良aEEG评分及S-100β、GFAP水平的改变,其均可作为儿童癫痫性脑病早期诊断指标,三者联合检测可提高诊断效能。 展开更多
关键词 改良aEEG评分 中枢神经特异蛋白s100β 神经胶质纤维酸性蛋白 儿童 癫痫性脑病
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TRUE KINGLY HONOUR IN SHAKESPEARE′S HENRY IV PART I
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作者 黄必康 《外语教学》 CSSCI 北大核心 1991年第4期25-30,共6页
Honour, one of the eternal themes in Shakespeare, is again in the spotlightin Henry IV Part I. In this play, the rivalry between Prince Hal and Hotspuremerges actually out of their cravings for the title of royal hono... Honour, one of the eternal themes in Shakespeare, is again in the spotlightin Henry IV Part I. In this play, the rivalry between Prince Hal and Hotspuremerges actually out of their cravings for the title of royal honour and valour.Hotspur appears to be formidable, courageous and energetic. He is exactly 展开更多
关键词 TRUE kingLY HONOUR IN sHAKEsPEARE s HENRY IV PART I IV
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Midnight Salivary Cortisol and Other Effective Factors in the Graduation of Clinical Suspect of Cushing Syndrome: Is There Any Reasonable Clinical Score?
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作者 Meral Mert Refik Tanakol +4 位作者 Hande Karpuzoglu Semra Abbasoglu Sema Yarman Harika Boztepe Faruk Alagol 《Open Journal of Endocrine and Metabolic Diseases》 2013年第1期52-54,共3页
Background: Diagnosis of Cushing’s Syndrome (CS) at the right time and with the right method is getting more important for the patients and clinicians due to high mortality rate. The most appropriate laboratory test ... Background: Diagnosis of Cushing’s Syndrome (CS) at the right time and with the right method is getting more important for the patients and clinicians due to high mortality rate. The most appropriate laboratory test will provide great benefits in terms of cost-effectiveness in the well-chosen group of patients. Selection of the high risk group is of crucial importance for the true diagnosis and treatment on time. Aim: The aim of this study was to evaluate the worth of the midnight salivary cortisol and to establish other effective factors in the graduation of clinical suspect of CS. Material and Methods: 115 patients were evaluated in weight, height, body mass index (BMI), waist/hip ratio, systolic, diastolic blood pressures, hirsutism, weight gain, purple-stria, plethore, buffalo-hump, supraclavicular fullness, temporal fat cushion, acnea, moonface, proximal muscle weakness, lower limb edema, ecchymosis, loss of libido, depression, diabetes mellitus, hypertension, allopecia of all patients were noted in the evaluation forms (23 findings). Patients were grouped according to clinical scores, low (16). Results: When we compare the groups in terms of midnight salivary cortisol, morning salivary cortisol after overnight dexamethasone suppression test, we found statistically significant relationship between the low and high clinical score groups, as well as between medium and high score groups (p: 0.0001). Urinary free cortisol was statistically significant only between low and high clinical score groups (p: 0.0001). Conclusion: This clinical scoring system which includes clinical signs and laboratory findings both, can be used for selection of the high risk group. 展开更多
关键词 sALIVARY Cortsiol CLINICAL sUsPECT CLINICAL score Cushing’s syndrome
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Nutech functional score: A novel scoring system to assess spinal cord injury patients
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作者 Geeta Shroff Jitendra Kumar Barthakur 《World Journal of Methodology》 2017年第2期68-72,共5页
AIM To develop a new scoring system, nutech functional scores(NFS) for assessing the patients with spinal cord injury(SCI).METHODS The conventional scale, American Spinal Injury Association's(ASIA) impairment scal... AIM To develop a new scoring system, nutech functional scores(NFS) for assessing the patients with spinal cord injury(SCI).METHODS The conventional scale, American Spinal Injury Association's(ASIA) impairment scale is a measure which precisely describes the severity of the SCI.However, it has various limitations which lead to incomplete assessment of SCI patients.We have developed a 63 point scoring system, i.e., NFS for patients suffering with SCI.A list of symptoms either common or rare that were found to be associated with SCI was recorded for each patient.On the basis of these lists, we have developed NFS.RESULTS These lists served as a base to prepare NFS, a 63 point positional(each symptom is sub-graded and get points based on position) and directional(moves in direction BAD → GOOD) scoring system.For non-progressive diseases, 1, 2, 3, 4, 5 denote worst, bad, moderate, good and best(normal), respectively.NFS for SCI has been divided into different groups based on the affected part of the body being assessed, i.e., motor assessment(shoulders, elbow, wrist, fingers-grasp, fingers-release, hip, knee, ankle and toe), sensory assessment, autonomic assessment, bed sore assessment and general assessment.As probability based studies required a range of(-1, 1) or at least the range of(0, 1) to be useful for real world analysis, the grades were converted to respective numeric values.CONCLUSION NFS can be considered as a unique tool to assess the improvement in patients with SCI as it overcomes the limitations of ASIA impairment scale. 展开更多
关键词 spinal cord injury American spinal Injury Association’s Impairment scale Nutech functional score Comparison of assessment Positional scoring system
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Assessing gestational age of babies: Performance of obstetric ultrasound scan compared to that from the combination of Naegle’s rule and Dubowitz score in the 21st century
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作者 Baba Usman Ahmadu 《Natural Science》 2013年第8期32-35,共4页
Background: Some researchers have suggested that when Naegle’s rule (NR) and Dubowitz score (DS) are combined, it could out-perform obstetric ultrasound scan (USS). Others still believe that obstetric USS alone is st... Background: Some researchers have suggested that when Naegle’s rule (NR) and Dubowitz score (DS) are combined, it could out-perform obstetric ultrasound scan (USS). Others still believe that obstetric USS alone is still effective relative to the combination of NR rule and DS in assessing the gestational age (GA) of babies. Objectives: To determine and compare the GA of babies using obstetric USS, NR and DS;and to provide relevant public health information on obstetric USS in the 21st century. Methods: Subjects were selected using systematic random sampling and the GA of babies was determined using obstetric USS, NR, and DS. Statistical package for social science (SPSS) statistical software version 16, Illinois, Chicago USA was used for all data analysis. Results: Eightyfive mother-baby pairs were studied. Forty-four babies (52%) were males and 41 (48%) females. Sixty four (75%) were term with a mean (SD) BW of 3.02 (0.59) at 95%CI (2.89 -?3.14) kg. The overall mean GA of the babies was 38.49 (2.89) at 95%CI (38.14 -?38.85) weeks. The mean GA using obstetric USS, NR and DS were 38.52 (1.98) at 95%CI (38.14 -?38.99), 38.09 (4.13) at 95%CI (37.20-?38.99) and 38.82 (2.02) at 95%CI (38.39 -?39.26), but comparison of these means was not significant (p = 0.256). Combined mean GA by NR and DS was 38.46 (3.26) at 95%CI (37.96 -?38.95). Comparing this mean with mean GA obtained by obstetric USS was also not significant (p = 0.885). Conclusion: The GA assessments by Obstetric USS, NR and DS were all reliable, and Obstetric USS performed effectively relative to combined NR and DS. 展开更多
关键词 GEsTATIONAL Age Babies OBsTETRIC Ultrasound sCAN Naegle’s RULE Dubowitz score Maiduguri NIGERIA
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Re-Formulation of Mean King’s Problem Using Shannon’s Entropy
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作者 Masakazu Yoshida Hideki Imai 《Journal of Quantum Information Science》 2013年第1期6-9,共4页
Mean King’s problem is formulated as a retrodiction problem among noncommutative observables. In this paper, we reformulate Mean King’s problem using Shannon’s entropy as a first step of introducing quantum uncerta... Mean King’s problem is formulated as a retrodiction problem among noncommutative observables. In this paper, we reformulate Mean King’s problem using Shannon’s entropy as a first step of introducing quantum uncertainty relation with delayed classical information. As a result, we give informational and statistical meanings to the estimation on Mean King problem. As its application, we give an alternative proof of nonexistence of solutions of Mean King’s problem for qubit system without using entanglement. 展开更多
关键词 Mean king’s PROBLEM QUANTUM Retrodiction PROBLEM QUANTUM Estimation PROBLEM shannon’s ENTROPY
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TCL——King Brand Colour TV Rivals the World's Famous Brands
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《China's Foreign Trade》 1996年第2期44-44,共1页
World famous colour TVs,such asSony,National and Toshiba,usedto monopolize China’s large-screencolour TV market.But recently the KingBrand colour TV made by the TCL ElectronicsGroup has begun to challenge them.In1995... World famous colour TVs,such asSony,National and Toshiba,usedto monopolize China’s large-screencolour TV market.But recently the KingBrand colour TV made by the TCL ElectronicsGroup has begun to challenge them.In1995,the TCL King Brand colour TV notonly ranked first for its sales volume on theChinese market among the domestically-produced TVs of its kind,but also 展开更多
关键词 TCL king Brand Colour TV Rivals the World’s Famous Brands TV World
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