AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint condition...AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function(PROMIS~? PF) computerized adaptive test(CAT), hip disability and osteoarthritis outcome score for joint reconstruction(HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction(KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchorbased and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.RESULTS There were 2226 patients who participated with a mean age of 61.16(SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS~? PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS~? PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.CONCLUSION This is the first comprehensive study providing a wide range of MCIDs for the PROMIS? PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments.展开更多
目的探讨关节镜下半月板成形术治疗膝关节半月板损伤患者的效果及对Lysholm评分、关节生理功能的影响。方法选取2017年9月—2020年2月在本院行关节镜下治疗的膝关节半月板损伤106例患者,据治疗方法不同分为观察组及对照组各53例,观察组...目的探讨关节镜下半月板成形术治疗膝关节半月板损伤患者的效果及对Lysholm评分、关节生理功能的影响。方法选取2017年9月—2020年2月在本院行关节镜下治疗的膝关节半月板损伤106例患者,据治疗方法不同分为观察组及对照组各53例,观察组采用关节镜下半月板成形术治疗,对照组采用关节镜下半月板切除术治疗。比较2组术后临床疗效和手术前后疼痛程度、关节活动度、膝关节功能及生活质量改善情况;术后随访6个月,了解2组术后并发症发生情况。结果术后观察组总有效率显著高于对照组(P<0.05);术后,2组视觉模拟评分法(visual analogue score,VAS)评分明显降低,关节活动度及Lysholm评分、国际膝关节评分委员会(international knee documentation committee,IKDC)膝关节主观功能评分明显升高,且术后观察组VAS评分下降程度、关节活动度及Lysholm评分、IKDC膝关节主观功能评分升高程度均大于对照组,差异均有统计学意义(P<0.05或P<0.01);观察组术后改良美国特种外科医院膝关节总评分明显高于对照组(P<0.01);术后,2组世界卫生组织生存质量测定量表简表(World Health Organization quality of life scale-brief form questionnaire,WHOQOL-BREF)社会功能、物质生活、躯体功能、心理功能评分均明显升高,且观察组术后WHOQOL-BREF量表各领域评分均显著高于对照组,差异均有统计学意义(P<0.05或P<0.01);随访期间2组均未发现明显并发症。结论对膝关节半月板损伤患者行关节镜下半月板成形术治疗,具有令人满意的临床效果,并且可以有效改善患者疼痛程度,促进患膝关节生理功能恢复,提高患者生活质量。展开更多
基金National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health,No.U01AR067138.
文摘AIM To establish minimum clinically important difference(MCID) for measurements in an orthopaedic patient population with joint disorders.METHODS Adult patients aged 18 years and older seeking care for joint conditions at an orthopaedic clinic took the Patient-Reported Outcomes Measurement Information System Physical Function(PROMIS~? PF) computerized adaptive test(CAT), hip disability and osteoarthritis outcome score for joint reconstruction(HOOS JR), and the knee injury and osteoarthritis outcome score for joint reconstruction(KOOS JR) from February 2014 to April 2017. MCIDs were calculated using anchorbased and distribution-based methods. Patient reports of meaningful change in function since their first clinic encounter were used as an anchor.RESULTS There were 2226 patients who participated with a mean age of 61.16(SD = 12.84) years, 41.6% male, and 89.7% Caucasian. Mean change ranged from 7.29 to 8.41 for the PROMIS~? PF CAT, from 14.81 to 19.68 for the HOOS JR, and from 14.51 to 18.85 for the KOOS JR. ROC cut-offs ranged from 1.97-8.18 for the PF CAT, 6.33-43.36 for the HOOS JR, and 2.21-8.16 for the KOOS JR. Distribution-based methods estimated MCID values ranging from 2.45 to 21.55 for the PROMIS~? PF CAT; from 3.90 to 43.61 for the HOOS JR, and from 3.98 to 40.67 for the KOOS JR. The median MCID value in the range was similar to the mean change score for each measure and was 7.9 for the PF CAT, 18.0 for the HOOS JR, and 15.1 for the KOOS JR.CONCLUSION This is the first comprehensive study providing a wide range of MCIDs for the PROMIS? PF, HOOS JR, and KOOS JR in orthopaedic patients with joint ailments.
文摘目的探讨关节镜下半月板成形术治疗膝关节半月板损伤患者的效果及对Lysholm评分、关节生理功能的影响。方法选取2017年9月—2020年2月在本院行关节镜下治疗的膝关节半月板损伤106例患者,据治疗方法不同分为观察组及对照组各53例,观察组采用关节镜下半月板成形术治疗,对照组采用关节镜下半月板切除术治疗。比较2组术后临床疗效和手术前后疼痛程度、关节活动度、膝关节功能及生活质量改善情况;术后随访6个月,了解2组术后并发症发生情况。结果术后观察组总有效率显著高于对照组(P<0.05);术后,2组视觉模拟评分法(visual analogue score,VAS)评分明显降低,关节活动度及Lysholm评分、国际膝关节评分委员会(international knee documentation committee,IKDC)膝关节主观功能评分明显升高,且术后观察组VAS评分下降程度、关节活动度及Lysholm评分、IKDC膝关节主观功能评分升高程度均大于对照组,差异均有统计学意义(P<0.05或P<0.01);观察组术后改良美国特种外科医院膝关节总评分明显高于对照组(P<0.01);术后,2组世界卫生组织生存质量测定量表简表(World Health Organization quality of life scale-brief form questionnaire,WHOQOL-BREF)社会功能、物质生活、躯体功能、心理功能评分均明显升高,且观察组术后WHOQOL-BREF量表各领域评分均显著高于对照组,差异均有统计学意义(P<0.05或P<0.01);随访期间2组均未发现明显并发症。结论对膝关节半月板损伤患者行关节镜下半月板成形术治疗,具有令人满意的临床效果,并且可以有效改善患者疼痛程度,促进患膝关节生理功能恢复,提高患者生活质量。
