利用计算流体力学商业软件FLUENT,建立了含采砂坑明渠立面的二维数学模型,其中,封闭方程采用标准k~ε模型的紊流方程,自由表面采用Volume of Fluid（VOF）方法模拟.在与明渠水流实验数据对比的基础上,研究了不同矩形采砂坑长度、深度和...利用计算流体力学商业软件FLUENT,建立了含采砂坑明渠立面的二维数学模型,其中,封闭方程采用标准k~ε模型的紊流方程,自由表面采用Volume of Fluid（VOF）方法模拟.在与明渠水流实验数据对比的基础上,研究了不同矩形采砂坑长度、深度和面积对明渠水位降低的影响.结果表明：当采砂坑面积相同时,长深比越大,水位降落越明显,长度的增加对水位跌落影响较大;随着采砂坑深度、长度增大,水位降落呈现缓慢增加、急剧增大和再平缓增大3个阶段,对应的单位坑深、局部水头损失呈现急剧上升、急剧下降、缓慢下降3个阶段.展开更多
In this paper,various aspects of the 2D and 3D nonlinear liquid sloshing problems in vertically excited containers have been studied numerically along with the help of a modified-transformation.Based on this new numer...In this paper,various aspects of the 2D and 3D nonlinear liquid sloshing problems in vertically excited containers have been studied numerically along with the help of a modified-transformation.Based on this new numerical algorithm,a numerical study on a regularly and randomly excited container in vertical direction was conducted utilizing four different cases： The first case was performed utilizing a 2D container with regular excitations.The next case examined a regularly excited 3D container with two different initial conditions for the liquid free surface,and finally,3D container with random excitation in the vertical direction.A grid independence study was performed along with a series of validation tests.An iteration error estimation method was used to stop the iterative solver（used for solving the discretized governing equations in the computational domain） upon reaching steady state of results at each time step.In the present case,this method was found to produce quite accurate results and to be more time efficient as compared to other conventional stopping procedures for iterative solvers.The results were validated with benchmark results.The wave elevation time history,phase plane diagram and surface plots represent the wave nonlinearity during its motion.展开更多
The proprietary Chinese medicine preparation Kaiyu Granule is made of bupleurum, nutgrass ga- lingale rhizome, szechwan Iovage rhizome, turmeric root tuber, white peony alba, cape jasmine fruit fried semen ziziphi juj...The proprietary Chinese medicine preparation Kaiyu Granule is made of bupleurum, nutgrass ga- lingale rhizome, szechwan Iovage rhizome, turmeric root tuber, white peony alba, cape jasmine fruit fried semen ziziphi jujubae, and prepared liquorice root. It is a common recipe for the clinical treatment of depression in China. In this study, after 21 days of unpredictable stress exposure, Wistar rats exhibited similar behavioral changes to patients with depression. Moreover, G-protein-coupled inwardly rectifying K＋ channel 1 mRNA and protein expression were significantly reduced in rat hippocampal CA1 and CA3 regions. However, G-protein-coupled inwardly rectifying K＋ channel 1 mRNA, protein expression, and rat behavior were clearly better after administration of 12, 8, or 4 g/kg of Kaiyu Granule when depression model rats underwent stress. 12 g/kg of Kaiyu Granule had the most obvious effects on the increased expression of G-protein-coupled inwardly rectifying K＋ channel 1 mRNA and protein in rat hippocampal CA1 and CA3 regions. These results suggested that Kaiyu Granule improved depression by affecting G-protein-coupled inwardly recti- fying K＋ channel 1 expression in the rat hippocampus.展开更多
Abstract： The shortest path problem in a network G is to find shortest paths between some specified source vertices and terminal vertices when the lengths of edges are given. The structure of the optimal solutions se...Abstract： The shortest path problem in a network G is to find shortest paths between some specified source vertices and terminal vertices when the lengths of edges are given. The structure of the optimal solutions set on the shortest paths is studied in this paper. First, the conditions of having unique shortest path between two distinguished vertices 8 and t in a network G are discussed; Second, the structural properties of 2-transformation ^-G graph G on the shortest-paths for G are presented heavily.展开更多
A total synthesis of (E,E)-3,7-dimethyl-2,6-decadiene-1,10-diol, using 1,3-transformation of 2, 3-epoxy alcohol and Claisen rearrangement of allyl vinyl ether as key steps, is described.
文摘利用计算流体力学商业软件FLUENT,建立了含采砂坑明渠立面的二维数学模型,其中,封闭方程采用标准k~ε模型的紊流方程,自由表面采用Volume of Fluid（VOF）方法模拟.在与明渠水流实验数据对比的基础上,研究了不同矩形采砂坑长度、深度和面积对明渠水位降低的影响.结果表明：当采砂坑面积相同时,长深比越大,水位降落越明显,长度的增加对水位跌落影响较大;随着采砂坑深度、长度增大,水位降落呈现缓慢增加、急剧增大和再平缓增大3个阶段,对应的单位坑深、局部水头损失呈现急剧上升、急剧下降、缓慢下降3个阶段.
文摘In this paper,various aspects of the 2D and 3D nonlinear liquid sloshing problems in vertically excited containers have been studied numerically along with the help of a modified-transformation.Based on this new numerical algorithm,a numerical study on a regularly and randomly excited container in vertical direction was conducted utilizing four different cases： The first case was performed utilizing a 2D container with regular excitations.The next case examined a regularly excited 3D container with two different initial conditions for the liquid free surface,and finally,3D container with random excitation in the vertical direction.A grid independence study was performed along with a series of validation tests.An iteration error estimation method was used to stop the iterative solver（used for solving the discretized governing equations in the computational domain） upon reaching steady state of results at each time step.In the present case,this method was found to produce quite accurate results and to be more time efficient as compared to other conventional stopping procedures for iterative solvers.The results were validated with benchmark results.The wave elevation time history,phase plane diagram and surface plots represent the wave nonlinearity during its motion.
基金supported by the New Drug Development Special-Purpose Foundation of State Administration of Traditional Chinese Medicine,No.2005 DIX027A
文摘The proprietary Chinese medicine preparation Kaiyu Granule is made of bupleurum, nutgrass ga- lingale rhizome, szechwan Iovage rhizome, turmeric root tuber, white peony alba, cape jasmine fruit fried semen ziziphi jujubae, and prepared liquorice root. It is a common recipe for the clinical treatment of depression in China. In this study, after 21 days of unpredictable stress exposure, Wistar rats exhibited similar behavioral changes to patients with depression. Moreover, G-protein-coupled inwardly rectifying K＋ channel 1 mRNA and protein expression were significantly reduced in rat hippocampal CA1 and CA3 regions. However, G-protein-coupled inwardly rectifying K＋ channel 1 mRNA, protein expression, and rat behavior were clearly better after administration of 12, 8, or 4 g/kg of Kaiyu Granule when depression model rats underwent stress. 12 g/kg of Kaiyu Granule had the most obvious effects on the increased expression of G-protein-coupled inwardly rectifying K＋ channel 1 mRNA and protein in rat hippocampal CA1 and CA3 regions. These results suggested that Kaiyu Granule improved depression by affecting G-protein-coupled inwardly recti- fying K＋ channel 1 expression in the rat hippocampus.
文摘Abstract： The shortest path problem in a network G is to find shortest paths between some specified source vertices and terminal vertices when the lengths of edges are given. The structure of the optimal solutions set on the shortest paths is studied in this paper. First, the conditions of having unique shortest path between two distinguished vertices 8 and t in a network G are discussed; Second, the structural properties of 2-transformation ^-G graph G on the shortest-paths for G are presented heavily.
文摘A total synthesis of (E,E)-3,7-dimethyl-2,6-decadiene-1,10-diol, using 1,3-transformation of 2, 3-epoxy alcohol and Claisen rearrangement of allyl vinyl ether as key steps, is described.
