A novel chiral bonded stationary phase(CBSP) for ligand exchange chromatography was prepared by bonding ( S ) 1,2,3,4 tetrahydro 3 isoquinoline carboxylic acid prepared from L Phe to YWG 80 silica gel via 3 glycidylox...A novel chiral bonded stationary phase(CBSP) for ligand exchange chromatography was prepared by bonding ( S ) 1,2,3,4 tetrahydro 3 isoquinoline carboxylic acid prepared from L Phe to YWG 80 silica gel via 3 glycidyloxypropyltrimethoxysilane as a coupling agent. Chromatographic resolutions of some DL amino acids were achieved on the CBSP by using an aqueous solution of 2 mmol/L N(C 2H 5) 3, 2 mmol/L HAc and 0 2 mmol/L Cu(Ac) 2 as the mobile phase with a flow rate 1 0 mL/min, column temperature 50 ℃ and detection at 254 nm. The enantioselectivity α of the DL amino acids on the CBSP was found to be between 1 11 and 1 51. The elution order of D isomer before L isomer on the CBSP was observed for all the DL amino acids resolved except DL Val. For DL Pro, DL Val and DL Leu the elution order through the CBSP was different from that through the chiral ligand exchange phases prepared from L Pro or L hydroxyl proline with a five\|membered ring structure. [WT5HZ]展开更多
complex[Ni(La) 2 ](NO 3 )2 (1)with bidentate racemic1,2,2-trimethylcyclopentane-1,3-diamine lig-and has been synthesized and characterized by IR,EA,ES-MS,and its X-ray diffracti on study reveals that the nickel (Ⅱ)ab...complex[Ni(La) 2 ](NO 3 )2 (1)with bidentate racemic1,2,2-trimethylcyclopentane-1,3-diamine lig-and has been synthesized and characterized by IR,EA,ES-MS,and its X-ray diffracti on study reveals that the nickel (Ⅱ)abstract: center is tetra-coordinated by one D-and one L-diamine ligands,and a thre e-dimensional hydrogen-bond-sustained network is formed in the solid state by means of the eight-membered N-H...O hydrogen bond cy-cle.This compound also su pplies a good comparison to the chiral complex[Ni(L b )2 ]Cl 2 ·2H 2 O(2)(L b =D-(+)abstract:-1,2,2-trimethylcyclopentane-1,3-diamine)abstract:.CCDC:218122.展开更多
文摘A novel chiral bonded stationary phase(CBSP) for ligand exchange chromatography was prepared by bonding ( S ) 1,2,3,4 tetrahydro 3 isoquinoline carboxylic acid prepared from L Phe to YWG 80 silica gel via 3 glycidyloxypropyltrimethoxysilane as a coupling agent. Chromatographic resolutions of some DL amino acids were achieved on the CBSP by using an aqueous solution of 2 mmol/L N(C 2H 5) 3, 2 mmol/L HAc and 0 2 mmol/L Cu(Ac) 2 as the mobile phase with a flow rate 1 0 mL/min, column temperature 50 ℃ and detection at 254 nm. The enantioselectivity α of the DL amino acids on the CBSP was found to be between 1 11 and 1 51. The elution order of D isomer before L isomer on the CBSP was observed for all the DL amino acids resolved except DL Val. For DL Pro, DL Val and DL Leu the elution order through the CBSP was different from that through the chiral ligand exchange phases prepared from L Pro or L hydroxyl proline with a five\|membered ring structure. [WT5HZ]
文摘complex[Ni(La) 2 ](NO 3 )2 (1)with bidentate racemic1,2,2-trimethylcyclopentane-1,3-diamine lig-and has been synthesized and characterized by IR,EA,ES-MS,and its X-ray diffracti on study reveals that the nickel (Ⅱ)abstract: center is tetra-coordinated by one D-and one L-diamine ligands,and a thre e-dimensional hydrogen-bond-sustained network is formed in the solid state by means of the eight-membered N-H...O hydrogen bond cy-cle.This compound also su pplies a good comparison to the chiral complex[Ni(L b )2 ]Cl 2 ·2H 2 O(2)(L b =D-(+)abstract:-1,2,2-trimethylcyclopentane-1,3-diamine)abstract:.CCDC:218122.
