Proactive Semantic Interference (PSI) and failure to recover from PSI (frPSI), are novel constructs assessed by the LASSI-L. These measures are sensitive to cognitive changes in early Mild Cognitive Impairment (MCI) a...Proactive Semantic Interference (PSI) and failure to recover from PSI (frPSI), are novel constructs assessed by the LASSI-L. These measures are sensitive to cognitive changes in early Mild Cognitive Impairment (MCI) and preclinical AD determined by Aβ load using PET. The goal of this study was to compare a new computerized version of the LASSI-L (LASSI-Brief Computerized) to the standard paper-and-pencil version of the test. In this study, we examined 110 cognitively unimpaired (CU) older adults and 79 with amnestic MCI (aMCI) who were administered the paper-and-pencil form of the LASSI-L. Their performance was compared with 62 CU older adults and 52 aMCI participants examined using the LASSI-BC. After adjustment for covariates (degree of initial learning, sex, education, and language of evaluation) both the standard and computerized versions distinguished between aMCI and CU participants. The performance of CU and aMCI groups using either form was relatively commensurate. Importantly, an optimal combination of Cued B2 recall and Cued B1 intrusions on the LASSI-BC yielded an area under the ROC curve of .927, a sensitivity of 92.3% and specificity of 88.1%, relative to an area under the ROC curve of .815, a sensitivity of 72.5%, and a specificity of 79.1% obtained for the paper-and-pencil LASSI-L. Overall, the LASSI-BC was comparable, and in some ways, superior to the paper-and-pencil LASSI-L. Advantages of the LASSI-BC include a more standardized administration, suitability for remote assessment, and an automated scoring mechanism that can be verified by a built-in audio recording of responses.展开更多
高中生学习策略量表(Learning and Study Strategies Inventory for High School Version,LASSI-HS)是Weinstein等在其1987年编制的大学生学习策略量表(LASSI)基础上针对高中生学习特点修订而成的一套学习策略测评工具,目前在国外已被...高中生学习策略量表(Learning and Study Strategies Inventory for High School Version,LASSI-HS)是Weinstein等在其1987年编制的大学生学习策略量表(LASSI)基础上针对高中生学习特点修订而成的一套学习策略测评工具,目前在国外已被广泛使用。该工具有助于教师具体了解学生现用的学习策略,或者帮助学生了解自己的学习策略,旨在为学生学习策略的改进提供依据。鉴于目前尚缺乏一套经过严格测量学属性检验的LASSI-HS中文修订版,本研究对LASSI-HS进行修订并考察其测量学属性,遵循标准的量表修订程序,最终修订出含有28个项目的中文版本的高中生学习策略量表(Learning and Study Strategies Inventory for High School, Chinese Version, LASSI-HS-CV)。结果表明:该量表具有良好的心理测量属性,可用于高中生学习策略的评测。展开更多
During the prodromal stage of Alzheimer’s disease (AD), neurodegenerative changes can be identified by measuring volumetric loss in AD-prone brain regions on MRI. Cognitive assessments that are sensitive enough to me...During the prodromal stage of Alzheimer’s disease (AD), neurodegenerative changes can be identified by measuring volumetric loss in AD-prone brain regions on MRI. Cognitive assessments that are sensitive enough to measure the early brain-behavior manifestations of AD and that correlate with biomarkers of neurodegeneration are needed to identify and monitor individuals at risk for dementia. Weak sensitivity to early cognitive change has been a major limitation of traditional cognitive assessments. In this study, we focused on expanding our previous work by determining whether a digitized cognitive stress test, the Loewenstein-Acevedo Scales for Semantic Interference and Learning, Brief Computerized Version (LASSI-BC) could differentiate between Cognitively Unimpaired (CU) and amnestic Mild Cognitive Impairment (aMCI) groups. A second focus was to correlate LASSI-BC performance to volumetric reductions in AD-prone brain regions. Data was gathered from 111 older adults who were comprehensively evaluated and administered the LASSI-BC. Eighty-seven of these participants (51 CU;36 aMCI) underwent MR imaging. The volumes of 12 AD-prone brain regions were related to LASSI-BC and other memory tests correcting for False Discovery Rate (FDR). Results indicated that, even after adjusting for initial learning ability, the failure to recover from proactive semantic interference (frPSI) on the LASSI-BC differentiated between CU and aMCI groups. An optimal combination of frPSI and initial learning strength on the LASSI-BC yielded an area under the ROC curve of 0.876 (76.1% sensitivity, 82.7% specificity). Further, frPSI on the LASSI-BC was associated with volumetric reductions in the hippocampus, amygdala, inferior temporal lobes, precuneus, and posterior cingulate.展开更多
1.Iassie(苏格兰和新英格兰英语)少女;少妇Scotland has been famed for its breathtakingscenery,but it seems now they have a new attraction-Scott lassies.苏格兰一向以优美的风光。现如今,妩媚动人的苏格兰少女又是一道亮丽的风...1.Iassie(苏格兰和新英格兰英语)少女;少妇Scotland has been famed for its breathtakingscenery,but it seems now they have a new attraction-Scott lassies.苏格兰一向以优美的风光。现如今,妩媚动人的苏格兰少女又是一道亮丽的风景线。2.colleen(多用于爱尔兰)少女All-hotel.tom found that Irish colleens werepreferred to sexy Scandinavians.全球酒店网站调查发现;相对于一贯以性感著称的斯堪的纳维亚佳丽,爱尔兰少女更受青睐。展开更多
文摘Proactive Semantic Interference (PSI) and failure to recover from PSI (frPSI), are novel constructs assessed by the LASSI-L. These measures are sensitive to cognitive changes in early Mild Cognitive Impairment (MCI) and preclinical AD determined by Aβ load using PET. The goal of this study was to compare a new computerized version of the LASSI-L (LASSI-Brief Computerized) to the standard paper-and-pencil version of the test. In this study, we examined 110 cognitively unimpaired (CU) older adults and 79 with amnestic MCI (aMCI) who were administered the paper-and-pencil form of the LASSI-L. Their performance was compared with 62 CU older adults and 52 aMCI participants examined using the LASSI-BC. After adjustment for covariates (degree of initial learning, sex, education, and language of evaluation) both the standard and computerized versions distinguished between aMCI and CU participants. The performance of CU and aMCI groups using either form was relatively commensurate. Importantly, an optimal combination of Cued B2 recall and Cued B1 intrusions on the LASSI-BC yielded an area under the ROC curve of .927, a sensitivity of 92.3% and specificity of 88.1%, relative to an area under the ROC curve of .815, a sensitivity of 72.5%, and a specificity of 79.1% obtained for the paper-and-pencil LASSI-L. Overall, the LASSI-BC was comparable, and in some ways, superior to the paper-and-pencil LASSI-L. Advantages of the LASSI-BC include a more standardized administration, suitability for remote assessment, and an automated scoring mechanism that can be verified by a built-in audio recording of responses.
文摘高中生学习策略量表(Learning and Study Strategies Inventory for High School Version,LASSI-HS)是Weinstein等在其1987年编制的大学生学习策略量表(LASSI)基础上针对高中生学习特点修订而成的一套学习策略测评工具,目前在国外已被广泛使用。该工具有助于教师具体了解学生现用的学习策略,或者帮助学生了解自己的学习策略,旨在为学生学习策略的改进提供依据。鉴于目前尚缺乏一套经过严格测量学属性检验的LASSI-HS中文修订版,本研究对LASSI-HS进行修订并考察其测量学属性,遵循标准的量表修订程序,最终修订出含有28个项目的中文版本的高中生学习策略量表(Learning and Study Strategies Inventory for High School, Chinese Version, LASSI-HS-CV)。结果表明:该量表具有良好的心理测量属性,可用于高中生学习策略的评测。
文摘During the prodromal stage of Alzheimer’s disease (AD), neurodegenerative changes can be identified by measuring volumetric loss in AD-prone brain regions on MRI. Cognitive assessments that are sensitive enough to measure the early brain-behavior manifestations of AD and that correlate with biomarkers of neurodegeneration are needed to identify and monitor individuals at risk for dementia. Weak sensitivity to early cognitive change has been a major limitation of traditional cognitive assessments. In this study, we focused on expanding our previous work by determining whether a digitized cognitive stress test, the Loewenstein-Acevedo Scales for Semantic Interference and Learning, Brief Computerized Version (LASSI-BC) could differentiate between Cognitively Unimpaired (CU) and amnestic Mild Cognitive Impairment (aMCI) groups. A second focus was to correlate LASSI-BC performance to volumetric reductions in AD-prone brain regions. Data was gathered from 111 older adults who were comprehensively evaluated and administered the LASSI-BC. Eighty-seven of these participants (51 CU;36 aMCI) underwent MR imaging. The volumes of 12 AD-prone brain regions were related to LASSI-BC and other memory tests correcting for False Discovery Rate (FDR). Results indicated that, even after adjusting for initial learning ability, the failure to recover from proactive semantic interference (frPSI) on the LASSI-BC differentiated between CU and aMCI groups. An optimal combination of frPSI and initial learning strength on the LASSI-BC yielded an area under the ROC curve of 0.876 (76.1% sensitivity, 82.7% specificity). Further, frPSI on the LASSI-BC was associated with volumetric reductions in the hippocampus, amygdala, inferior temporal lobes, precuneus, and posterior cingulate.
文摘1.Iassie(苏格兰和新英格兰英语)少女;少妇Scotland has been famed for its breathtakingscenery,but it seems now they have a new attraction-Scott lassies.苏格兰一向以优美的风光。现如今,妩媚动人的苏格兰少女又是一道亮丽的风景线。2.colleen(多用于爱尔兰)少女All-hotel.tom found that Irish colleens werepreferred to sexy Scandinavians.全球酒店网站调查发现;相对于一贯以性感著称的斯堪的纳维亚佳丽,爱尔兰少女更受青睐。
