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肝癌干细胞标志物最新进展 被引量:3
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作者 吴超 张金玲 +1 位作者 杨盛力 赵志辉 《肝胆外科杂志》 2013年第4期309-311,共3页
1肿瘤干细胞理论 肿瘤干细胞理论认为,在肿瘤组织中存在有一种或几种具有干细胞特性的细胞亚群,即肿瘤干细胞(cancerstemcells,CSC),和正常干细胞一样,CSC具有自我复制和定向分化能力,只有CSC才有无限增殖和形成新生肿瘤的能... 1肿瘤干细胞理论 肿瘤干细胞理论认为,在肿瘤组织中存在有一种或几种具有干细胞特性的细胞亚群,即肿瘤干细胞(cancerstemcells,CSC),和正常干细胞一样,CSC具有自我复制和定向分化能力,只有CSC才有无限增殖和形成新生肿瘤的能力,肿瘤中占绝大多数的分化肿瘤细胞不能形成肿瘤,CSC是肿瘤生长、复发和转移的根源。CSC是一种“状态”,并非是一个固定的细胞群体,CSC和非CSC之间是一种动态变化的关系,可以互相转化, 展开更多
关键词 肝癌 干细胞 lcscs 标志物 肿瘤
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Experimental and theoretical study on the break phenomenon of self-pulsation for liquid-centered swirl coaxial injectors 被引量:3
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作者 Peng-jin CAO Xiao BAI +1 位作者 Qing-lian LI Peng CHENG 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2022年第2期140-155,共16页
Experimental observations together with theoretical analysis were conducted to investigate the break phenomenon and the corresponding mechanisms of self-pulsation for a liquid-centered swirl coaxial injector with rece... Experimental observations together with theoretical analysis were conducted to investigate the break phenomenon and the corresponding mechanisms of self-pulsation for a liquid-centered swirl coaxial injector with recess number of RN=1.Instantaneous spray images were obtained based on background light imaging technology with a high-speed camera.By dynamic analysis of the flow process of the liquid sheet in the recess chamber,a 1D self-pulsation theoretical model was established,and the self-sustaining mechanisms of self-pulsation were analyzed in depth.The results show that the increase of the momentum flux ratio will lead to the occurrence of the break phenomenon of self-pulsation for the injector with a larger recess length,and the frequency and intensity of self-pulsation before and after the break phenomenon differ significantly.The flow dynamics in the recess chamber sequentially transform from a periodic expansion-dominated flow to a stable flow,and then develop to a periodic contraction-dominated flow during the break process of self-pulsation.With the occurrence of self-pulsation before the break phenomenon,the liquid sheet has little effect on the pressure disturbance in the recess chamber.In contrast,with the occurrence of self-pulsation after the break phenomenon,the pressure disturbance is obviously affected by the liquid sheet.Based on the theoretical analysis model of self-pulsation,the self-pulsation frequency can be predicted.Furthermore,the self-sustaining mechanism of self-pulsation before and after the break phenomenon is preliminarily confirmed.The energy transfer between the gas-and liquid-phase is an important factor for maintaining the self-pulsation process. 展开更多
关键词 Break phenomenon Theoretical model of self-pulsation Pressure oscillation characteristics RECESS Liquid-centered swirl coaxial(LCSC)injector
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