Objectives: Peripheral neuropathy (PN) is a significant contributor to disability in the elderly. It is also one of the most prevalent complications of type 2 diabetes, prediabetes and metabolic syndrome. PN is common...Objectives: Peripheral neuropathy (PN) is a significant contributor to disability in the elderly. It is also one of the most prevalent complications of type 2 diabetes, prediabetes and metabolic syndrome. PN is commonly associated with pain, numbness, tingling, burning, and cramping in the feet and legs. Current treatment options are limited to controlling pain, seizures and use of antidepressant medications. These treatments have undesirable side effects and don’t stop PN progression. Here we utilized a combination of individual-specific modalities to improve local circulation and relieve PN symptoms. Methods: We conducted an open-label, multicenter pilot trial with 34 subjects (19 males and 15 females ranging from 40 - 85 years of age). All of the participants were diagnosed with peripheral neuropathy and had bilateral symptoms in their feet, and many reported the same symptoms (pain, numbness, tingling, burning, and cramping) in their lower legs. The duration of symptoms ranged from four months to over six years. On Day 0, subjects were given a 90-day supply of the oral supplement with dosing instructions and a LED light therapy device. They also received three platelet-rich plasma (PRP) injections in their lower extremities. Subjects also received an extracorporeal shockwave therapy (ESWT) treatment for each foot and subsequently twice per week for the first six weeks, then once weekly for the duration of the study. Subjects filled out the Brief Pain Index (BPI) at weekly intervals. On Day 90, subjects completed the Patient Global Impression of Change (PGIC) survey. Results: There were significant responses to pain, as evidenced by BPI scores at weeks 8, 9, 10 and 11 (p = 0.02, 0.01, 0.02, and 0.003, respectively). Analysis of the final day PGIC survey showed a favorable outcome for 73% of participants (p = 0.003), with the majority reporting Very Much Improved. Conclusions: By utilizing a multi-modality treatment protocol that includes PRP, LED light therapy, ESWT and an oral dietary supplement, we observed significant reductions in BPI scores. Quality of life and their overall impression of change (PGIC) were significantly improved, and there were no significant side effects.展开更多
Significantly enhanced electroluminescence performance and stability of all-inorganic perovskite light-emitting devices(PeLEDs) have been achieved by adding triton X-100 into the perovskite precursors.The small perovs...Significantly enhanced electroluminescence performance and stability of all-inorganic perovskite light-emitting devices(PeLEDs) have been achieved by adding triton X-100 into the perovskite precursors.The small perovskite grains arranged tightly and formed large grains as the triton X-100 were introduced.Thus the nonradiative defects originated from Pb atoms at the grain boundaries were highly passivated by triton X-100 and resulted in the promotion of PeLED performance,including a turn-on voltage of 3.2 V,a brightness of 63500 cd/m^(2),a current efficiency of 17.4 cd/A,and a prolonged lifetime of 2 h in air.展开更多
A set of novel red phosphors Li_(8)CaLa_(2)Ta_(2)O_(13):Eu^(3+)(LCLTO:xEu^(3+))were successfully prepared using a solid-state reaction method.The properties of the prepared samples,including phase purity,elemental com...A set of novel red phosphors Li_(8)CaLa_(2)Ta_(2)O_(13):Eu^(3+)(LCLTO:xEu^(3+))were successfully prepared using a solid-state reaction method.The properties of the prepared samples,including phase purity,elemental composition,and morphology,were systematically investigated using X-ray diffraction,scanning electron microscopy,and diffuse reflectance spectroscopy analyses.The 610 nm maximum emission peak is attributed to the^(5)D_(0)→^(7)F_(2)transition of Eu^(3+)ion under 394 nm irradiation.Among all the LCLTO:xEu^(3+)phosphors,LCLTO:0.6Eu^(3+)showed the strongest emission intensity because of the concentration quenching effect of the electric dipole-dipole in-teraction among the Eu^(3+)ions,which was also demonstrated by the decay curves.Remarkably,the emission intensity of the optimal LCLTO:0.6Eu^(3+)phosphor,which exhibited a high internal quantum efficiency of 49.30%and excellent color purity of 96.79%,was approximately 2.29 times higher than that of commercial Y203:Eu^(3+)red phosphors.The thermal stability of the LCLTO:0.6Eu^(3+)sample with good color stability was meticulously inves-tigated.The fabricated white-light-emitting diode(WLED)exhibited a superior color-rendering index of Ra=82 and chromaticity coordinates of(0.3260,0.3639),suggesting that LCLTO:0.6Eu^(3+)has potential applicability in developing efficient and high-quality WLEDs.Moreover,the prepared LCLTO:0.6Eu^(3+)/PDMS composite film demonstrated exceptional flexural resistance and chemical stability,indicating considerable promise for practical anti-counterfeitingapplications.展开更多
The magnetic improvised explosive devices (IEDs), also commonly known as a type of a sticky bomb, is simply constructed devices yet very lethal. This paper puts forward the idea of an electronic compass that is capa...The magnetic improvised explosive devices (IEDs), also commonly known as a type of a sticky bomb, is simply constructed devices yet very lethal. This paper puts forward the idea of an electronic compass that is capable of sensing the change of a magnetic field generated by a magnet and translating it into interpretable data, which could act as the base for the further studies and assist in developing a greener automated system for detecting this device. The electronic compass is specifically chosen for reducing power consumption of systems in addition to the fact that it is available at a low cost.展开更多
A nonlinearity measurement of the charge-coupled device(CCD) array spectrometer using flux addition and comparison method is described. The light with various colors from the colorful light emitting diode(LED) light s...A nonlinearity measurement of the charge-coupled device(CCD) array spectrometer using flux addition and comparison method is described. The light with various colors from the colorful light emitting diode(LED) light source is applied to measure the nonlinearity of the spectrometer at different wavelengths, respectively. An high-end CCD array spectrometer is tested. For colorful LED light sources, the nonlinearity factors of the CCD array spectrometer(absolute value) are as follows: k<0.8% for white light, k <1.1% for red light, k <2.2% for green light and k<4.7% for blue light. By using those quasi-monochromatic light sources, it is shown that the nonlinearity depends on the wavelength. It is important to be wariness about the spectral nonlinearity and related uncertainty evaluation when the narrow-band light source is tested.展开更多
All-inorganic perovskites are rapidly emerging as novel optoelectronic functional materials owing to their flu-orescence properties.However,the stability of these materials has always been the biggest challenge for th...All-inorganic perovskites are rapidly emerging as novel optoelectronic functional materials owing to their flu-orescence properties.However,the stability of these materials has always been the biggest challenge for their applications in photoelectric devices.Therefore,this study focuses on developing phosphor-aluminosilicate-based CsPbX_(3)(X=Cl,Br,and I)glass with a low reaction temperature by adding CsCO_(3),PbX_(2),and NaX to the raw materials in order to improve the stabilities.The glass network intermediates of SiO_(2) and Al_(2)O_(3) doping in the raw material enhanced the stability of the pure phosphate glass network structure and devitrification while decreas-ing the melting temperature.Full chromatographic CsPbX 3 quantum dots(QDs)encapsulated in phosphate-based glass were found to increase the fluorescence properties and quantum efficiency(>59%).Notably,the high water stability of CsPbX_(3) QDs glasses,with the maintenance of 90% luminous intensity,emerged when soaked in water.In addition,the excellent thermal stability and anti-ion exchange properties of the CsPbX_(3) QDs glasses were re-vealed.Benefiting from the above,multicolor light-emitting diode(LED)devices were assembled with a mixture of phosphors of CsPbX_(3) QDs glasses and commercial red-emission K 2 SiF 6:Mn 4+phosphor spread on an InGaN chip,demonstrating bright light with superior luminous properties.Phosphor-aluminosilicate-based CsPbX_(3) QDs glass with high stability and low formation temperature would provide new methods for applications in lighting and displays.展开更多
A series of new oxyapatite red phosphors Ca_(3) Y_(7)(BO_(4)) (SiO_(4))_(5) O doped with different concentrations of Eu^(3+)were successfully synthesized by high temperature solid state method.The X-ray diffraction(XR...A series of new oxyapatite red phosphors Ca_(3) Y_(7)(BO_(4)) (SiO_(4))_(5) O doped with different concentrations of Eu^(3+)were successfully synthesized by high temperature solid state method.The X-ray diffraction(XRD)Rietveld refinement results show that the structure of the phosphor belongs to space group P6_(3)/m and Eu^(3+)ion replaces Y^(3+)ion.The emission spectrum consists of the characteristic emission peaks corresponding to Eu^(3+)under the excitation of 274 nm and the dominant emission peak is at 614 nm(^(5)D_(0)→^(7)F_(2) of Eu^(3+)).The concentration quenching effect occurs and the optimized Eu^(3+)concentration is 4.0 mol%.The energy level diagram for luminous mechanism is also given and the non-radiative energy transfer mechanism between Eu^(3+)is mainly exchange interaction.The CIE coordinate is close to the ideal red light and the color purity is higher than 99.79%.Moreover,the phosphor exhibits moderate thermal stability because the photoluminescence intensity at 423 K is still maintained at higher than 78.97%of that at room temperature.The internal quantum efficiency of Ca_(3) Y_(7)(BO_(4)) (SiO_(4))_(5) O:4.0 mol%Eu^(3+)phosphor is 58.2%.A red light emitting diode(LED)device based on it can emit bright red light.The CCT values of the device are basically unchanged when driven by various bias current.The results show that Ca_(3) Y_(7)(BO_(4)) (SiO_(4))_(5) O:Eu^(3+)is a new type of oxyapatite red fluorescent material with good comprehensive performances.展开更多
The two-dimensional(2D)materials have been widely developed recently in material characteristics with advanced optical and electrical properties,and they have been extensively studied as candidates for the next genera...The two-dimensional(2D)materials have been widely developed recently in material characteristics with advanced optical and electrical properties,and they have been extensively studied as candidates for the next generation of optoelectronic devices.This review will mainly focus on the preparation methods and the light emitting applications of 2D transition metal dichalcogenides(TMDs),2D black phosphorene(BP)and 2D perovskites.The review will first introduce the preparation methods for TMDs and BP.Due to the variations of band structure,exciton binding energies and light-matter interaction in TMDs and BP,the different light emitting devices(LEDs)designs based on TMDs and BP will be discussed and summarized.Then the review will turn the focus to 2D perovskites,starting with a description of the preparation methods for the different structural perovskites.In order to review and summarize the achievements of 2D perovskites-based LEDs,the high efficiency perovskites LEDs are discussed.Finally,the review will present challenges,opportunities,and outlook for the future development of 2D materials-based light emitting applications.展开更多
文摘Objectives: Peripheral neuropathy (PN) is a significant contributor to disability in the elderly. It is also one of the most prevalent complications of type 2 diabetes, prediabetes and metabolic syndrome. PN is commonly associated with pain, numbness, tingling, burning, and cramping in the feet and legs. Current treatment options are limited to controlling pain, seizures and use of antidepressant medications. These treatments have undesirable side effects and don’t stop PN progression. Here we utilized a combination of individual-specific modalities to improve local circulation and relieve PN symptoms. Methods: We conducted an open-label, multicenter pilot trial with 34 subjects (19 males and 15 females ranging from 40 - 85 years of age). All of the participants were diagnosed with peripheral neuropathy and had bilateral symptoms in their feet, and many reported the same symptoms (pain, numbness, tingling, burning, and cramping) in their lower legs. The duration of symptoms ranged from four months to over six years. On Day 0, subjects were given a 90-day supply of the oral supplement with dosing instructions and a LED light therapy device. They also received three platelet-rich plasma (PRP) injections in their lower extremities. Subjects also received an extracorporeal shockwave therapy (ESWT) treatment for each foot and subsequently twice per week for the first six weeks, then once weekly for the duration of the study. Subjects filled out the Brief Pain Index (BPI) at weekly intervals. On Day 90, subjects completed the Patient Global Impression of Change (PGIC) survey. Results: There were significant responses to pain, as evidenced by BPI scores at weeks 8, 9, 10 and 11 (p = 0.02, 0.01, 0.02, and 0.003, respectively). Analysis of the final day PGIC survey showed a favorable outcome for 73% of participants (p = 0.003), with the majority reporting Very Much Improved. Conclusions: By utilizing a multi-modality treatment protocol that includes PRP, LED light therapy, ESWT and an oral dietary supplement, we observed significant reductions in BPI scores. Quality of life and their overall impression of change (PGIC) were significantly improved, and there were no significant side effects.
基金Project supported by the National Key Research and Development Program of China(Grant Nos.2018YFA0305900 and 2016YFA0300404)the National Natural Science Foundation of China(Grant Nos.11874172,11374120,11634004,and 51320105007)the Science and Technology Innovative Research Project of Jilin University,China(Grant No.2017TD-01)。
文摘Significantly enhanced electroluminescence performance and stability of all-inorganic perovskite light-emitting devices(PeLEDs) have been achieved by adding triton X-100 into the perovskite precursors.The small perovskite grains arranged tightly and formed large grains as the triton X-100 were introduced.Thus the nonradiative defects originated from Pb atoms at the grain boundaries were highly passivated by triton X-100 and resulted in the promotion of PeLED performance,including a turn-on voltage of 3.2 V,a brightness of 63500 cd/m^(2),a current efficiency of 17.4 cd/A,and a prolonged lifetime of 2 h in air.
基金supported by the Foundation of Fujian Province(No.2021J011149)the financial support of Innovative Research Team of Ningde Normal University(No.2023T03)Fujian Provincial Department of Education(No.JAT210469).
文摘A set of novel red phosphors Li_(8)CaLa_(2)Ta_(2)O_(13):Eu^(3+)(LCLTO:xEu^(3+))were successfully prepared using a solid-state reaction method.The properties of the prepared samples,including phase purity,elemental composition,and morphology,were systematically investigated using X-ray diffraction,scanning electron microscopy,and diffuse reflectance spectroscopy analyses.The 610 nm maximum emission peak is attributed to the^(5)D_(0)→^(7)F_(2)transition of Eu^(3+)ion under 394 nm irradiation.Among all the LCLTO:xEu^(3+)phosphors,LCLTO:0.6Eu^(3+)showed the strongest emission intensity because of the concentration quenching effect of the electric dipole-dipole in-teraction among the Eu^(3+)ions,which was also demonstrated by the decay curves.Remarkably,the emission intensity of the optimal LCLTO:0.6Eu^(3+)phosphor,which exhibited a high internal quantum efficiency of 49.30%and excellent color purity of 96.79%,was approximately 2.29 times higher than that of commercial Y203:Eu^(3+)red phosphors.The thermal stability of the LCLTO:0.6Eu^(3+)sample with good color stability was meticulously inves-tigated.The fabricated white-light-emitting diode(WLED)exhibited a superior color-rendering index of Ra=82 and chromaticity coordinates of(0.3260,0.3639),suggesting that LCLTO:0.6Eu^(3+)has potential applicability in developing efficient and high-quality WLEDs.Moreover,the prepared LCLTO:0.6Eu^(3+)/PDMS composite film demonstrated exceptional flexural resistance and chemical stability,indicating considerable promise for practical anti-counterfeitingapplications.
基金supported by the Malaysia Ministry of Higher Education under FRGS Grant No.6071306
文摘The magnetic improvised explosive devices (IEDs), also commonly known as a type of a sticky bomb, is simply constructed devices yet very lethal. This paper puts forward the idea of an electronic compass that is capable of sensing the change of a magnetic field generated by a magnet and translating it into interpretable data, which could act as the base for the further studies and assist in developing a greener automated system for detecting this device. The electronic compass is specifically chosen for reducing power consumption of systems in addition to the fact that it is available at a low cost.
基金supported by the National Natural Science Foundation of China(No.61505191)
文摘A nonlinearity measurement of the charge-coupled device(CCD) array spectrometer using flux addition and comparison method is described. The light with various colors from the colorful light emitting diode(LED) light source is applied to measure the nonlinearity of the spectrometer at different wavelengths, respectively. An high-end CCD array spectrometer is tested. For colorful LED light sources, the nonlinearity factors of the CCD array spectrometer(absolute value) are as follows: k<0.8% for white light, k <1.1% for red light, k <2.2% for green light and k<4.7% for blue light. By using those quasi-monochromatic light sources, it is shown that the nonlinearity depends on the wavelength. It is important to be wariness about the spectral nonlinearity and related uncertainty evaluation when the narrow-band light source is tested.
基金This work was supported in part by the China Postdoctoral Science Foundation(No.2022M711438)'the Natural Science Foundation of Shandong Province(ZR2020ME045 and ZR2020ME046)'the“New Universities 20”Foundation of Jinan(Grant No.2021GXRC099).
文摘All-inorganic perovskites are rapidly emerging as novel optoelectronic functional materials owing to their flu-orescence properties.However,the stability of these materials has always been the biggest challenge for their applications in photoelectric devices.Therefore,this study focuses on developing phosphor-aluminosilicate-based CsPbX_(3)(X=Cl,Br,and I)glass with a low reaction temperature by adding CsCO_(3),PbX_(2),and NaX to the raw materials in order to improve the stabilities.The glass network intermediates of SiO_(2) and Al_(2)O_(3) doping in the raw material enhanced the stability of the pure phosphate glass network structure and devitrification while decreas-ing the melting temperature.Full chromatographic CsPbX 3 quantum dots(QDs)encapsulated in phosphate-based glass were found to increase the fluorescence properties and quantum efficiency(>59%).Notably,the high water stability of CsPbX_(3) QDs glasses,with the maintenance of 90% luminous intensity,emerged when soaked in water.In addition,the excellent thermal stability and anti-ion exchange properties of the CsPbX_(3) QDs glasses were re-vealed.Benefiting from the above,multicolor light-emitting diode(LED)devices were assembled with a mixture of phosphors of CsPbX_(3) QDs glasses and commercial red-emission K 2 SiF 6:Mn 4+phosphor spread on an InGaN chip,demonstrating bright light with superior luminous properties.Phosphor-aluminosilicate-based CsPbX_(3) QDs glass with high stability and low formation temperature would provide new methods for applications in lighting and displays.
基金Project supported by the National Natural Science Foundation of China(51972213,61605116,51972208,51802196).
文摘A series of new oxyapatite red phosphors Ca_(3) Y_(7)(BO_(4)) (SiO_(4))_(5) O doped with different concentrations of Eu^(3+)were successfully synthesized by high temperature solid state method.The X-ray diffraction(XRD)Rietveld refinement results show that the structure of the phosphor belongs to space group P6_(3)/m and Eu^(3+)ion replaces Y^(3+)ion.The emission spectrum consists of the characteristic emission peaks corresponding to Eu^(3+)under the excitation of 274 nm and the dominant emission peak is at 614 nm(^(5)D_(0)→^(7)F_(2) of Eu^(3+)).The concentration quenching effect occurs and the optimized Eu^(3+)concentration is 4.0 mol%.The energy level diagram for luminous mechanism is also given and the non-radiative energy transfer mechanism between Eu^(3+)is mainly exchange interaction.The CIE coordinate is close to the ideal red light and the color purity is higher than 99.79%.Moreover,the phosphor exhibits moderate thermal stability because the photoluminescence intensity at 423 K is still maintained at higher than 78.97%of that at room temperature.The internal quantum efficiency of Ca_(3) Y_(7)(BO_(4)) (SiO_(4))_(5) O:4.0 mol%Eu^(3+)phosphor is 58.2%.A red light emitting diode(LED)device based on it can emit bright red light.The CCT values of the device are basically unchanged when driven by various bias current.The results show that Ca_(3) Y_(7)(BO_(4)) (SiO_(4))_(5) O:Eu^(3+)is a new type of oxyapatite red fluorescent material with good comprehensive performances.
文摘The two-dimensional(2D)materials have been widely developed recently in material characteristics with advanced optical and electrical properties,and they have been extensively studied as candidates for the next generation of optoelectronic devices.This review will mainly focus on the preparation methods and the light emitting applications of 2D transition metal dichalcogenides(TMDs),2D black phosphorene(BP)and 2D perovskites.The review will first introduce the preparation methods for TMDs and BP.Due to the variations of band structure,exciton binding energies and light-matter interaction in TMDs and BP,the different light emitting devices(LEDs)designs based on TMDs and BP will be discussed and summarized.Then the review will turn the focus to 2D perovskites,starting with a description of the preparation methods for the different structural perovskites.In order to review and summarize the achievements of 2D perovskites-based LEDs,the high efficiency perovskites LEDs are discussed.Finally,the review will present challenges,opportunities,and outlook for the future development of 2D materials-based light emitting applications.