砂轮磨削振动对工件表面形貌特征的影响研究

砂轮振动将会使得光学元件表面产生周期性波动,从而降低后续抛光工序的加工效率,增加光学元件表面的中频误差成分,影响光学元件的使用性能。本文针对平行磨削方式,研究了砂轮周期性强迫振动下的工件表面形貌特征,分析了砂轮与工件表面的干涉现象,以及加工参数对加工表面波纹度特征的影响。研究结果表明:加工参数满足一定的条件下,工件表面振纹小于砂轮本身振动振幅,通过合理选择加工参数有利于改善工件表面波纹度,提高加工表面质量。

用驻极体技术改进脂质体包封血红蛋白制备的实验研究

为改进脂质体包封血红蛋白（ＬＥＨ，即人工红细胞）制备技术，获得可输入实验动物体内的ＬＥＨ，以生物驻极体理论为指导，应用驻极体技术对ＬＥＨ进行极化处理，调整其驻极体特性，使其与生物体环境相适应。本研究制备四种经不同极化处理的ＬＥＨ。首先对四种ＬＥＨ应用热释电技术测试了它们的驻极体性能，表明将正极化后的Ｈｂ包封制成ＬＥＨ再行负极化得到的４号ＬＥＨ驻极体性能最好。其次对该种ＬＥＨ粘度及聚集性的观察，发现其粘度与人血相类似，而抗聚性要强于人红细胞。再次，观察了血液与４号ＬＥＨ不同配比对体外血栓形成的影响，结果表明血液中４号ＬＥＨ浓度为２０％，抑制血栓形成效果最优。最后依此浓度，观察了四种ＬＥＨ对体外血栓形成的影响，发现具有不同驻极体特性的ＬＥＨ对血栓形成影响各异。比天然人红细胞驻极体性能弱的１、２号ＬＥＨ，可促进体外血栓形成，表现出与人体血液驻极体性能的不匹配性。比天然人红细胞驻极体性能强的的ＬＥＨ可抑制体外血栓形成，表现出与人体血液驻极体性能良好的相容性，本项研究提示：（１）运用驻极体技术对ＬＥＨ进行调整，使其更适应生物体的生理环境，完善了ＬＥＨ制备技术，为进一步ＬＥＨ输注动物体内研究奠定了材料基础。（２）ＬＥＨ?

Progress in octahedral spherical hohlraum study

In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility.

脂质体包封血红蛋白体外对血液流变性影响的研究

本文对脂质体包封血红蛋白（LEH）体外对血液流变性影响进行初步研究。观察了几种不同磷脂组成和配比的脂质体与 LEH对体外血栓形成、血液粘度和红细胞聚集指数的影响。研究发现，ＬＥＨ能使血液粘度降低，并可改善红细胞聚集指数，ＬＥＨ加入到血液中不会导致血栓形成，尚有轻微减缓体外血栓形成作用。

驻极体技术改进的脂质体包封血红蛋白及其对体外血液流变学性能的影响

为了研究脂质体包封血红蛋白 (L iposom e Encapsulated Hemoglobin,L EH)的不同带电性能对体外血液流变性的影响 ,用驻极体技术制备了四种不同带电性能的 L EH。利用热刺激去极化电流法 (Therm ally Stimulat-ed Depolarization Current,TSDC)对它们的驻极体性能进行了测试 ,发现 4#L EH (主峰温度 Tα=12℃ ,主峰电流Iα=- 5 .6× 10 - 9A)的性能最好 ,而且体外血栓成形实验结果表明 ,添加 4#L EH形成血栓重量最小。可见 ,利用驻极体技术对 L EH的表面电性能进行合理的改进 ,就能改善红细胞及血液的流变性能 。

印度Leh地区沙棘叶中脂肪酸的含量

本文用气相色谱仪分析了印度Leh地区沙棘叶油中种脂肪酸的含量,结果显示:该地区沙棘叶油中富含硬脂酸,其值可以达到13.853%,山嵛酸13.938%,亚油酸7.579%,掬焦油酸6.638%,十八稀酸4.622%。

Geotechnical Investigation of Slopes along the National Highway (NH-1D) from Kargil to Leh, Jammu and Kashmir (India)

The national highways are always considered as the economic backbone of the country and have often assisted development work all along their routes. The National Highway (NH-1D) is the most strategic and the only all weather surface link between the two districts of Ladakh region (Kargil and Leh). The area under investigation experiences high vehicular traffic, particularly between March and August, as in the remaining months the Kargil and Leh districts?remain cutoff?from each other due to bad weather. In recent years, frequent occurrences of slope failures along the highway primarily affect the smooth functioning of the traffic movement which severely affects the life of the people of the area. Strategically, this road network is very important and plays a significant role in transportation and other activities. In order to ensure the stability of road network in the area, it becomes extremely important to understand the triggering mechanism of these failures. The present study made an attempt in this direction and the Slope Mass Rating (SMR) method has been used for slope stability analysis at different locations. The stability of the slopes was also assessed using kinematic analysis conjointly with SMR to identify the types of failure and its potential failure directions associated with each slope. The result obtained after calculating RMR from the selected facets ranges from 11 to 89 with lower values indicating presence of potentially unstable areas. Results have shown that in a total of 20 facets, 65.28% belong to wedge failure, 22.26%?belong to toppling failure and 12.45% belong to plane failure.

猪LEH异源输注猫的研究

在小动物临床急救医学中,输血疗法是很重要的一种不可替代的治疗方法,但因动物血型较多、血型鉴定和配血试验费时费力,且有效储存期短,目前国内尚无储存血源供应,以上因素均限制了该治疗方法的应用。脂质体是一种利用天然材料磷脂和胆固醇制备的类似细胞膜的生物制品,具有良好的生物相容性和靶向性,利用脂质体包裹血红蛋白,其具有可控制大小,同时脂质体可屏蔽无基质血红蛋白的毒副作用,且延长血红蛋白的血浆半衰期,无红细胞表面的抗原决定簇。猪源血红蛋白脂质体是制备动物通用红细胞的一个比较有前景的方法,可克服动物血型多、产生的输血反应和同源输血导致动物疾病的传播等妨碍动物临床输血发展的难题。